scholarly journals Evaluation of antioxidant and chemopreventive effect of Cocos nucifera L.

2018 ◽  
Vol 6 (2) ◽  
pp. 47-58
Author(s):  
Shrabanti Dev ◽  
Anha Afrin Shefa ◽  
Archana Mandal ◽  
Projit Roy Gayen ◽  
Kaniz Asma ◽  
...  
Keyword(s):  
Cocos Nucifera ◽  
Ethanolic Extract ◽  
Natural Antioxidants ◽  
Anticancer Activities ◽  
Initiation And Propagation ◽  
Ic50 Value ◽  
Activity Marker ◽  
Cocos Nucifera L ◽  
Preventive Role ◽  
Different Doses

This study revealed the antioxidant and anticancer activities of the ethanolic extract of the tender fruits of Cocos nucifera. In antioxidant screening, IC50 value was found to be 7.71μg/mlfor ascorbic acid and44.67 μg/ml for C. nucifera fruits. The phenolic content, total flavonoid and total tannin content were 537.89 mg GAE/100 gm, 40.69mg of QE/100 gm and 44.61 mg of GAE/100 gm of dry powder of C. nucifera respectively. In DMBA and croton oil-induced skin cancer in model mice,the extract significantly decreased the number, size, yield and burden of tumor when compared with carcinogenic control. The extract increased the level of natural antioxidants like GSH, SOD and Catalase. Moreover, substantial decrease in SGPT, SGOT (liver activity marker) was observed at different doses ofthe crude extract. Lipid profile of mice treated with C. nucifera was brought back to normal level to some extent when compared to carcinogenic control. In conclusion,C. nucifera fruits have antioxidant activity as well as preventive role on cancer initiation and propagation without major toxicity.Jahangirnagar University J. Biol. Sci. 6(2): 47-58, 2017 (December)

scholarly journals Antioxidant Potential of Ethanol and Ethyl Acetat Extract of Ganoderma sp. Mycelium

2018 ◽  
Vol 10 (1) ◽  
pp. 87-94
Author(s):  
Nuniek Ina Ratnaningtyas ◽  
Purnomowati Purnomowati ◽  
Endang Sri Purwati ◽  
Aisyah Tri Septiana ◽  
Nuraeni Ekowati ◽  
...  
Keyword(s):  
Ethyl Acetate ◽  
Research Result ◽  
Ethanolic Extract ◽  
Natural Antioxidants ◽  
Antioxidant Potential ◽  
Complete Medium ◽  
Central Java ◽  
Local Resources ◽  
Ic50 Value ◽  
Better Than

Ganoderma sp. Banyumas 1 isolate that reffered as Ganoderma sp. is a new discovered isolate from Banyumas, Central Java, Indonesia expected to have a potential properties of antioxidant of medicinal mushroom. This study aimed to determine the antioxidant potential and the appropriate solvent for it’s extracting from Ganoderma sp. This research result showed that ethyl acetate was able to extract as many as 15.57%, while etanol was only able to extract 3.87% active compounds from dried 28 days old Ganoderma sp. mycelium cultivated in the Mushroom Complete Medium (MCM). Extract of ethyl acetate (non-polar) extraction of mycelium of Ganoderma sp. had a potential character as an antioxidant source and performed a better result than from ethanolic (polar) extraction as shown in the IC50 value. Extract from ethyl acetate extraction had an average IC50 value smaller than  from ethanolic extract (581.80 < 1285.67). Extract from ethyl acetate extraction resulted in a higher amount of phenol than that ethanolic extract 29.23 < 57.67. Inhibition percentage of both extracts at 65% was known to occur at concentration of 1000 ppm for ethyl acetate extract and 2000 ppm for ethanolic extract. An important finding was that ethyl acetate can be used as appropriate solvent for extracting antioxidant compound better than ethanolic. In conclusion, the mycelium extract of Ganoderma sp. extracted with ethyl acetate and ethanol as solvent is potential to be used as a source of natural antioxidants. This research result has benefit in developing potency of local resources as herbal resources.

Growth of Dracaena marginata and Spathiphyllum ‘Petite’ in Sphagnum Peat- and Coconut Coir Dust-based Growing Media

1999 ◽  
Vol 17 (1) ◽  
pp. 49-52 ◽  
Author(s):  
Robert H. Stamps ◽  
Michael R. Evans
Keyword(s):  
Growth Parameters ◽  
Cocos Nucifera ◽  
Greenhouse Production ◽  
Growing Media ◽  
Sphagnum Peat ◽  
Affected Plant ◽  
Coir Dust ◽  
Media Component ◽  
The Media ◽  
Cocos Nucifera L

Abstract A comparison was made of Canadian sphagnum peat (SP) and Philippine coconut (Cocos nucifera L.) coir dust (CD) as growing media components for greenhouse production of Dracaena marginata Bak. and Spathiphyllum Schott ‘Petite’. Three soilless foliage plant growing mixes (Cornell, Hybrid, University of Florida #2 [UF-2]) were prepared using either SP or CD and pine bark (PB), vermiculite (V), and/or perlite (P) in the following ratios (% by vol): Cornell = 50 CD or SP:25 V:25 P, Hybrid = 40 CD or SP:30 V:30 PB, UF-2 = 50 CD or SP: 50 PB. Dracaena root growth was not affected by treatments but there were significant mix × media component interactions that affected plant top growth parameters. In general, the growth and quality of D. marginata were reduced by using CD in Cornell, had no effect in Hybrid, and increased in UF-2. S. ‘Petite’ grew equally well in all growing mixes regardless of whether CD or SP was used; however, plants grew more in Cornell and Hybrid than in UF-2. S. ‘Petite’ roots, which were infested with Cylindrocladium spathiphylli, had higher grades when grown in CD than when the media contained SP.

UJI AKTIVITAS ANTIOKSIDAN FRAKSI N-HEKSAN DAUN AFRIKA (Vernonia amygdalina Del.) DENGAN METODE DPPH

2020 ◽  
Vol 5 (2) ◽  
pp. 250-257
Author(s):  
Nurul Fatimah ◽  
◽  
Reksi Sundu
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Activity ◽  
Free Radicals ◽  
Ethanolic Extract ◽  
Ethanol Extract ◽  
Hexane Fraction ◽  
Phytochemical Screening ◽  
Vernonia Amygdalina ◽  
Tropical Africa ◽  
Ic50 Value

Free radicals and reactive species are widely believed to contribute to the development of several diseases by causing oxidative stress and eventually oxidative. Vernonia amygdalina (Astereacea) is a small shrub or tree between 1 and 5m high growing throughout tropical Africa. Plants are generally known as bitter leaves is well cultivated and is a general market for merchandise in several countries. The purpose of this study was to determine the antioxidant activity of hexane fraction from ethanol extract od Frican leaves (Vernonia amygdalina Del.). The method used in this study was the DPPH (1,1-Diphenil-2-Picrylhydrazyl) method. The result of phytochemical screening showed that ethanolic extract of African leaves contained a composition of secondary metabolites of alkaloids, flavonoids, tannins, steroids/triterpenoids and saponins. The antioxidant activity of the extract of n-hexane fraction was classified as very weak with an IC50 value of 317.98 ppm.

Cocos nucifera Linn. (Palmae) Husk Fiber Ethanolic Extract: Antioxidant Capacity and Electrochemical Investigation

2013 ◽  
Vol 16 (2) ◽  
pp. 121-129
Author(s):  
Monika Bezerra dos Santos Oliveira ◽  
Iara Barros Valentim ◽  
Camila Calado de Vasconcelos ◽  
Cristhiane Maria Bazílio Omena ◽  
Etelvino José Henriques Bechara ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Cocos Nucifera ◽  
Ethanolic Extract ◽  
Electrochemical Investigation

Diversity in Mohachao Narel, a Sweet Endosperm Coconut (Cocos nucifera L.) Population from Maharashtra, India

2013 ◽  
Vol 36 (3) ◽  
pp. 319-330 ◽  
Author(s):  
K. Samsudeen ◽  
M. K. Rajesh ◽  
D. D. Nagwaker ◽  
Raghavan Reshmi ◽  
P. Ajith Kumar ◽  
...  
Keyword(s):  
Cocos Nucifera ◽  
Cocos Nucifera L

Synergistic action of propolis with levodopa in the management of Parkinsonism in Drosophila melanogaster

2020 ◽  
Vol 17 (3) ◽  
Author(s):  
Emmanuel Tiyo Ayikobua ◽  
Josephine Kasolo ◽  
Keneth Iceland Kasozi ◽  
Ejike Daniel Eze ◽  
Abass Safiriyu ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Drosophila Melanogaster ◽  
Side Effects ◽  
Motor Activity ◽  
Ethanolic Extract ◽  
Synergistic Action ◽  
Content Type ◽  
Treatment Groups ◽  
Ethanolic Extract Of Propolis ◽  
Different Doses

AbstractBackgroundThe Phosphatase and tensin-induced putative kinase 1 (PINK1B9) mutant for Drosophila melanogaster is a key tool that has been used in assessing the pathology of Parkinsonism and its possible remedy. This research was targeted toward determining the effects of ethanolic extract of propolis, with levodopa therapy in the management of Parkinsonism.MethodThe PINK1B9 flies were divided into groups and fed with the different treatment doses of ethanoic extract of propolis. The treatment groups were subjected to 21 days of administration of propolis and the levodopa at different doses after which percentage climbing index, antioxidant activity and lifespan studies were done.ResultsPropolis alone improved motor activity, antioxidant and lifespan in Drosophila melanogaster than in PINK1 flies. Propolis in combination with levodopa significantly (P<0.05) improved physiological parameters at higher than lower concentrations in Parkinsonism Drosophila melanogaster demonstrating its importance in managing side effects associated with levodopa.ConclusionPropolis is a novel candidate as an alternative and integrative medicinal option to use in the management of Parkinsonism in both animals and humans at higher concentrations.

Cocos nucifera L. oil alleviates lead acetate-induced reproductive toxicity in sexually-matured male Wistar rats

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Olugbemi T. Olaniyan ◽  
Olakunle A. Ojewale ◽  
Ayobami Dare ◽  
Olufemi Adebayo ◽  
Joseph E. Enyojo ◽  
...  
Keyword(s):  
Luteinizing Hormone ◽  
Lead Acetate ◽  
Wistar Rats ◽  
Histological Analysis ◽  
Cocos Nucifera ◽  
Reproductive Toxicity ◽  
Positive Control ◽  
Negative Control ◽  
Male Wistar Rats ◽  
Cocos Nucifera L

Abstract Objectives Lead primarily affects male reproductive functions via hormonal imbalance and morphological damage to the testicular tissue with significant alteration in sperm profile and oxidative markers. Though, different studies have reported that Cocos nucifera L. oil has a wide range of biological effects, this study aimed at investigating the effect of Cocos nucifera L. oil on lead acetate-induced reproductive toxicity in male Wistar rats. Methods Twenty (20) sexually matured male Wistar rats (55–65 days) were randomly distributed into four groups (n=5). Group I (negative control)—distilled water orally for 56 days, Group II (positive control)—5 mg/kg bwt lead acetate intraperitoneally (i.p.) for 14 days, Group III—6.7 mL/kg bwt Cocos nucifera L. oil orally for 56 days and Group IV—lead acetate intraperitoneally (i.p.) for 14 days and Cocos nucifera L. oil for orally for 56 days. Rats were sacrificed by diethyl ether, after which the serum, testis and epididymis were collected and used for semen analysis, biochemical and histological analysis. Results The lead acetate significantly increases (p<0.05) testicular and epididymal malondialdehyde (MDA) levels, while a significant reduction (p<0.05) in sperm parameters, organ weight, testosterone and luteinizing hormone was observed when compared with the negative control. The coadministration of Cocos nucifera oil with lead acetate significantly increases (p<0.05) testosterone, luteinizing hormone, sperm parameters and organ weight, with a significant decrease (p<0.05) in MDA levels compared with positive control. Histological analysis showed that lead acetate distorts testicular cytoarchitecture and germ cell integrity while this was normalized in the cotreated group. Conclusions Cocos nucifera oil attenuates the deleterious effects of lead acetate in male Wistar rats, which could be attributed to its polyphenol content and antioxidant properties.

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