scholarly journals Role of Ultrasonography in The Differentiation of Solid Breast Mass

KYAMC Journal ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 204-207
Author(s):  
Fatama Sharmin ◽  
Nazif Sultana ◽  
Nazneen Akter ◽  
SM Mazharul Islam ◽  
Farhana Zaman

Background: Breast cancer is the major cause of cancer death in women. Breast ultrasound is of a great value in differentiating malignant from benign masses. Objective: To distinguish benign from malignant solid breast lesions by Ultrasonography (USG). Materials and Methods: This cross sectional study was performed in Radiology and Imaging department of Dhaka Community Medical College Hospital (DCMCH) in collaboration with the department of Pathology and Surgery, DCMCH from January 2017 to December 2017. The benign and malignant solid breast mass were differentiated by using USG and correlated these with histopathological findings. Results: Total 60 female with breast mass, aged 20 to 60 years, were studied. Out of 60 cases, 34 cases were solid breast mass on USG. Eleven cases were diagnosed as malignant and 23 cases as benign. Among the USG diagnosed 11 cases, 10 cases found truly malignant (true +ve) and 1 (one) case was benign (false+ve) whereas out of the 23 benign cases, 21 were benign (true -ve) and 2 (two) were found malignant(false-ve), and all were confirmed by histopathology.The sensitivity of USG for malignant breast mass was found 83.33% and specificity was 95.45%. The positive and negative predictive values of USG were 90.91% and 91.3% respectively. The diagnostic accuracy of USG in differentiating breast mass into malignant and benign was 91.318%. Conclusion: The USG is a very good diagnostic modality for differentiating benign and malignant breast mass. KYAMC Journal Vol. 11, No.-4, January 2021, Page 204-207

2016 ◽  
Vol 41 (2) ◽  
pp. 81-88
Author(s):  
Shyamal Kumar Roy ◽  
Sohely Sultana ◽  
Nazir Uddin Mollah ◽  
Tarana Yasmin ◽  
Asish Sarker ◽  
...  

This cross sectional study was carried enrolling 47 subjects with suspected solid liver mass, in the Department of Radiology and Imaging, Dhaka Medical College Hospital, Dhaka, over a period of twelve months. The aim of this study was to evaluate the diagnostic usefulness of transabdominal ultrasonography in the diagnosis of solid SOL in the liver. Majority of the respondents (42.55%) were found between 41-60 years of age. Five (10.63%) subjects were found below 20 years of age. There were 31 men (65.95%) and 16 women (34.05%). Majority of the metastasis were multiple (85%), hypoechoic (35%) and only 15% had internal calcifications. HCC was single lesion (61.53%) with hyperechoic (38.35%) echogenicity, with a central halo (76.92%) and 15.38% had internal calcifications. Majority of the cholangiocarcinoma were solitary (80%), hypoechoic (60%) and 60% had internal calcifications. Hepatoblastoma were solitary and had calcifications (60%) with mixed echogenicity (60%). Majority of the adenomas were solitary (80%), hypoechoic (60%) and only 20 % had internal calcifications. The validity of transabdominal sonography for the diagnosis of metastasis was confirmed by calculating sensitivity (100%), specificity (96.42%), accuracy (97.87%), positive (95%) and negative predictive (100%) values by using the standard formula given. The sensitivity, specificity, accuracy, positive and negative predictive values for HCC were 92.3%, 97.05%, 95.74%, 92.3% and 97.05% respectively. The sensitivity, specificity, accuracy, positive and negative predictive values for cholangiocarcinoma and hepatoblastoma were 80%, 97.61%, 95.74%, 80% and 97.61% respectively. Sensitivity, specificity, accuracy, positive and negative predictive values were 80%, 100%, 97.87%, 100% and 97.67% respectively for adenoma. From the study result it was concluded that transabdominal ultrasonography could be reliable, non-ionizing and relatively cheap procedure for diagnosis solid hepatic mass lesion.


2018 ◽  
Vol 4 (2) ◽  
pp. 53-57
Author(s):  
Lovely Yesmin ◽  
Rued Hossain ◽  
Bibekananda Haldar ◽  
Mohammad Sazzad Hossain ◽  
Sajida Nahid ◽  
...  

Background: Mammography is used for the detection of breast cancer.Objective: The purpose of the present study was to evaluate the diagnostic performance of Mammography in the diagnosis of benign and malignant breast mass.Methodology: This cross-sectional type of study was carried out in the Radiology & Imaging department of Sir Salimullah Medical College and Mitford Hospital, Dhaka, during July 2013 to June 2015. Patients clinically suspected as having breast mass, referred in the above mentioned hospitals and enrolled for surgical management were included in this study. Mammography were done in all these patients and they were followed up from the admission up to the post-operative tissue diagnosis of breast mass in respective pathology departments for histopathological correlation.Results: A total of 41 patients had mass among them, 3(7.3%) cases were malignant and 38(92.7%) cases were benign patients. Histopathological diagnosis of invasive ductal carcinoma, invasive lobular carcinoma and medullary carcinoma were 8(14. %), 4(7.00%) and 1(1.8%) respectively. Mammography malignant was found 14 cases out of which 10(76.9%) malignant and 4(9.1%) benign evaluated by histopathology. Mammography benign was found 43 cases out of which 3(23.1%) malignant and 40(90.9%) benign evaluated by histopathology. The sensitivity was 76.9%, specificity 90.9%, accuracy 87.7%, positive predictive values 71.4% and negative predictive values 93.0% in mammography.Conclusion:  Mammography is highly sensitive, specific, reliable and useful method in the differentiation of malignant and benign breast masses.Journal of Current and Advance Medical Research 2017;4(2):53-57


2015 ◽  
Vol 12 (1) ◽  
pp. 2-6
Author(s):  
Wahida Begum ◽  
Ahmed Hossain ◽  
Waziha A Jahan ◽  
Mahbuba Shirin ◽  
M Abdullah Yusuf ◽  
...  

Background: CT-scan is useful for the detection of hepatic mass. Objective: The purpose of the present study was to see the predictive values of CT scan in the diagnosis of malignant hepatic mass. Methodology: This cross sectional study was carried out in the Department of Radiology and Imaging at Mymensingh Medical College Hospital (MMCH), Mymensingh, Banghabandhu Sheikh Mujib Medical University (BSMMU), Dhaka and Dhaka Medical College Hospital (DMCH), Dhaka during the period of 1st January 2006 to 31st December 2007. Patients admitted in the Department of Medicine and Department of Hepatobiliary of MMCH, BSMMU, and DMCH with the clinical diagnosis of fever, abdominal pain, anorexia, nausea/vomiting, loss of appetite, jaundice, weight loss and ascites were selected as study population. CT scan and histopathology were performed to all the patients. Result: A total number of 50 patients were recruited for this study.. The sensitivity for multiplicity was 71.4%, specificity was 63.6%, accuracy was 68%, PPV was 71.4% and NPV was 63.6%. The sensitivity for hypodensity as a sign of malignancy was 60.7%, specificity was 18.2%, accuracy was 42.0%, PPV was 48.6% and NPV was 26.7%. The sensitivity, specificity, PPV, NPV and accuracy of contrast enhancement were 100.0%, 22.7%, 62.2%, 100.0% and 66.0% respectively. Again the sensitivity, specificity, PPV, NPV and accuracy of detection of pressure effect on biliary apparatus by CT-scan were 100.0%, 22.7%, 62.2%, 100.0% and 66.0% respectively. Again the sensitivity, specificity, PPV, NPV and accuracy of detection of Lymphadenopathy by CT-scan were 35.7%, 95.5%, 90.9%, 53.8% and 62.0% respectively. The sensitivity, specificity, PPV, NPV and accuracy of detection of Portal vein invasion by CT-scan were 14.3%, 100.0%, 100.0%, 47.8% and 52.0% respectively. The sensitivity, specificity, PPV, NPV and accuracy of detection of hepatic vein invasion by CT-scan were 10.7%, 100.0%, 100.0%, 46.8% and 50.0% respectively. The sensitivity, specificity, PPV, NPV and accuracy of detection of inferior vena cava (IVC) invasion by CT-scan were 7.1%, 100.0%, 100.0%, 45.8% and 48.0% respectively. Conclusion: CT is a useful diagnostic tool for the detection of malignant hepatic masses.Journal of Science Foundation, 2014;12(1):2-6


2015 ◽  
Vol 21 (1) ◽  
pp. 5-16
Author(s):  
Mohammad Obaidul Islam ◽  
Md Zakaria Sarker ◽  
Muddassir Mahmud ◽  
Mesbah Uddin Ahmed ◽  
Ashequr Rahman Bhuiyan ◽  
...  

Objective: To evaluate role of ultrasound guided FNAC for the diagnosis of parotid tumor.Methods: This cross sectional study was conducted in 39 patients with parotid tumor admitted in the ENT department of out door of Bangabandhu Sheikh Mujib Medical University, Dhaka Medical College Hospital, and Sir Salimullah Medical College and Mitford Hospital Dhaka, during July 2013 to June 2014 were enrolled for surgical management. Conventional FNAC and ultrasound guided FNAC were done in all these patients and they were followed up from the admission upto the post operative tissue diagnosis of parotid tumor in respective pathology departments for histopathological correlation.Results: The highest incidence of parotid tumor was in 4th decade and male to female ratio was almost 1:1. The main clinical feature were 27(69.2%) had firm, 6(15.4%) soft, 1(2.6%) hard and 5(12.8%) over the parotid tail. The validity of histopathology evaluation for pleomorphic in USG FNAC sensitivity 95.7%, specificity 100.0%, accuracy 97.4%, positive predictive values 100.0%, negative predictive values 94.1%. Evaluation for Meucoepidermoid sensitivity 80.0%, specificity 97.1%, accuracy 94.9%, positive predictive values 80.0%, negative predictive values 97.1% in USG FNAC. In USG FNAC for identification Warthin sensitivity 100.0%, specificity 100.0%, accuracy 100.0%, positive predictive values 100.0%, negative predictive values 100.0%. Evaluation for Adenocystic in USG FNAC sensitivity 100.0%, specificity 100.0%, accuracy 100.0%, positive predictive values 100.0%, negative predictive values 100.0%.Conclusion: It can be concluded that Ultrasound guided FNAC has definite value in the diagnosis of tumours and can be regarded as a sensitive and specific imaging modality for pre-operative discrimination of the benign and malignant parotid tumours.Bangladesh J Otorhinolaryngol; April 2015; 21(1): 5-16


2016 ◽  
Vol 4 (2) ◽  
pp. 26-31
Author(s):  
Mitheel Ibna Islam ◽  
Monowara Khatun ◽  
Md Shahidul Islam ◽  
Md Nurul Amin ◽  
Shitil Ibna Islam

Background and Objectives: Early diagnosis of clinical chorioamnionitis (ChAm) in patients with premature rupture of membrane (PROM) is essential for its prompt treatment with antibiotics. Amniocentesis may be used to detect subclinical infections in cases of PROM. But the procedure is an invasive one. The present study was undertaken to study the role of plasma C-reactive protein (CRP) in the prediction of clinical chorioamnionitis in case of PROM. Materials & Methods The cross-sectional study was carried out in the of Departments of Obstetrics & Gynaecology, Khulna Medical College Hospital, Khulna over a period 1 year from July 2014 to June 2015. A total of 90 clinically diagnosed cases of PROM (rupture of the membrane with release of the amniotic fluid more than 1 hour prior to the onset of labor) were consecutively included in the study based on predefined enrolment criteria. Clinical ChAm is defined by findings such as leukocytosis [WBC count, >15,000/µL, fetal tachycardia, maternal fever (temperature, >100.4°F), fundal or uterine tenderness, or foul-smelling amniotic fluid]. A CRP value of > 10 mg/L was considered as raised or positive CRP. The risk of developing clinical ChAm in patients with raised CRP was then estimated by computing the Odds ratio. Result: The mean age of the women with PROM was 23.9 years. The patients presented with fundal or uterine tenderness (10%), raised maternal temperature (8.9%), foetal tachycardia (10%), maternal tachycardia (13.3%), foul smelling amniotic fluid (6.7%). Over half (52.2%) of the patients were preterm PROM and the rest were term PROM. Positive CRP was found in 16.7% cases. Raised WBC count and raised ESR were found in 11.1 and 33.3% cases respectively. Over two-thirds (70%) who developed clinical chorioamnionitis had raised CRP as opposed to 10% of those who did not develop the condition. The risk of having raised CRP in patients who developed clinical chorioamnionitis was > 20-fold (4.5 - 97.7) higher than those who did not develop the condition (p < 0.001). The sensitivity and specificity of CRP in diagnosing and ruling out chorioamnionitis respectively in cases of PROM were 70% and 90% respectively. The positive and negative predictive values of the test are 46.7% and 96% respectively. Conclusion: The study concluded that a substantial proportion of the PROM cases with clinical chorioamnionitis is manifested with raised CRP compared to PROM cases without chorioamnionitis. However, CRP is moderately sensitive to diagnose chorioamnionitis and highly specific to rule out the condition in cases with PROM. Ibrahim Cardiac Med J 2014; 4(2): 26-31


2015 ◽  
Vol 22 (2) ◽  
pp. 167-172
Author(s):  
Mst Nazmun Nahar ◽  
Asifa Sattar ◽  
Husne Ara ◽  
Akanda Fazle Rabbi ◽  
Mahbuba Shirin ◽  
...  

The study was carried out to assess the diagnostic accuracy of transabdominal ultrasonography in the evaluation of clinically suspected ectopic pregnancy patients . This cross sectional study was carried out in the department of Radiology and Imaging, Dhaka Medical College Hospital, Dhaka, from July 2006 to June 2008. 50 patients were selected purposively and transabdominal ultrasonography was done in each patient by 3.5 MHz frequency curvilinearprobe. Findings of transabdominal ultrasonography were then compared with the peroperative findings. Transabdominal ultrasonography in the diagnosis of ectopic pregnancy showed a sensitivity of 79.5%, specificity of 83.3%, and accuracy of 80%. Positive predictive value was 97.2% and negativepredictive value was 55.6%. . This study shows thattransabdominal ultrasonographyis an effective modality in the evaluation of ectopic pregnancy and should be used as a routine first-step procedure in patients of suspected ectopic pregnancy. DOI: http://dx.doi.org/10.3329/jdmc.v22i2.21529 J Dhaka Medical College, Vol. 22, No.2, October, 2013, Page 167-172


2013 ◽  
Vol 20 (03) ◽  
pp. 381-384
Author(s):  
JAVED AHMED PHULPOTO

Diagnosing Tuberculous ascites is a challenge. Polymerase chain reaction (PCR) and adenosine deaminase activity(ADA) have come up as promising modalities to aid diagnosis of tuberculosis in body fluids. Objective: To find and compare theusefulness of ADA and PCR in ascitic fluid in diagnosis of peritoneal tuberculosis. Study Design: A cross-sectional study. Place of Study:Medical Unit-I, Ghulam Mohammad Mahar Medical College Hospital, Sukkur. Duration of Study: From January 2010 to July 2011.Methods: Fifty five patients of exudative ascites, were diagnosed as peritoneal tuberculosis by following criteria- clinical suspicion, PPD(Skin Tuberculin test) positive, suggestive bacteriological and/or imaging findings and ascitic fluid showing lymphocytosis withdecreased glucose and SAAG (Serum- Ascites albumin gradient) of <1.1 gm/ dL. PCR and ADA were performed in the ascitic fluid andpositivity rates determined and compared. Results: Out of 55 study subjects, 50 patients (90.9%) were PCR positive and 48 (87.3%)were ADA positive; both were equiefficacious (p=0.54). High agreement between PCR and ADA tests was noted. Conclusions: ADA andPCR are comparable as diagnostic modality for tuberculous peritonitis, however ADA scores over PCR because of easy availability, lowcost, less infrastructure requirement and less-time consuming.


2012 ◽  
Vol 6 (1) ◽  
pp. 11-13
Author(s):  
Sushmita Roy ◽  
S.M. Shamsuzzaman ◽  
K.Z. Mamun

Rotavirus is one of the leading causes of pediatric diarrhea globally. Accurate and rapid diagnosis of Rotavirus diarrhea should reduce unnecessary use of antibiotics and ultimately reduce drug resistance. Study was designed for rapid diagnosis of Rotavirus antigen in stool sample by ICT (Immunochromatographic test) as well as to observe the seasonal variation of rotavirus infection. This cross sectional study was carried out in the department of Microbiology, Dhaka Medical College from January 2011 to December 2011. Eighty stool samples were collected from Dhaka Shishu Hospital and Dhaka Medical College Hospital. All samples were tested for rotavirus antigen by ICT. Among 80 patients, 42 (52.5%) samples were positive for rotavirus antigen. Among these 42 positive samples, 30 (71.43%) were from 0-12 months of age group, 10 (23.81%) from 13 to 24 months of age group and rest 2 (4.76%) from 25 to 36 months of age group. Rotavirus Ag was detected in stool samples from January to April and another peak episode from October to December. Considering the importance of Rotavirus associated diarrhea, rapid detection of Rotavirus infection in human is substantially needed and should be routinely practiced.DOI: http://dx.doi.org/10.3329/bjmm.v6i1.19354 Bangladesh J Med Microbiol 2012; 06(01): 11-13


2021 ◽  
Vol 9 (2) ◽  
pp. 3-7
Author(s):  
Iffath Farooqui ◽  
Md Shamsul Islam ◽  
Rahat Amin Chowdhury ◽  
ATM Hasibul Hasan

The sexual assaults and its consequences are increasing along with socioeconomic development of the country. Rise of modern communication technology add fuel to the flame. This descriptive cross-sectional study aimed to evaluate the role of communication technology in sexual assaults in Bangladesh. There were 87 victims included in this study. All were female of 6 years to 40 years of age, mean age was 15.67 (± 6.69) year. Most of the victims were below 20 years of age and came from low income families. About 76% mobile used were smart phone. Among them 46% were owned by the victims herself, 26% gifted by the assailants to the victims. Talking through mobile (37%) was the main communication route between the assailants and the victims; followed by direct verbal (31%), mixed verbal and mobile talking (26%) and others (6%). Regarding methods of communication, they only talk in 42% cases and 36% cases used mixed method (talking, SMS and video chatting). The assailant paid all the costs in 62% cases. Mobile phone came as a blessing in communication, but inchoate use makes it a curse to our society. Parents should be cautious about their children's mobile usage (especially smart phone) daily. Government also should make some policy on using mobile technology by the younger citizens. CBMJ 2020 July: Vol. 09 No. 02 P: 03-07


2013 ◽  
Vol 3 (1) ◽  
pp. 29-31
Author(s):  
Swapna Bhattacharjee ◽  
Shekhar Bhattacharjee ◽  
Rukhsana Parvin

Background: Cough variant asthma (CVA) is a subset of asthma where the only symptom is chronic persistent cough. Many cases go unrecognized due to lack of proper evaluation. Response to asthma medication with features supportive of airway hypersensitivity helps in management of this disease. Objective: To find out the proportion of cough variant asthma among the patients attending medicine outpatient department of Enam Medical College, Savar, Dhaka. Materials and Methods: This cross sectional study was conducted in Enam Medical College Hospital, Savar, Dhaka over a period of two years from July 2009 to July 2011. Cough variant asthma was diagnosed mainly on clinical ground as chronic cough without wheezing, fever, weight loss, shortness of breath or sputum or any other apparent cause that persisted for more than eight weeks with absolutely normal physical examination of chest, normal chest radiography and blood count except raised eosinophil count and IgE level. Patients who met these criteria were given 2 weeks course of inhaler beclomethasone propionate and were assessed for improvement. Those who improved after steroid inhalation were categorised as having cough variant asthma. Results: Out of purposively selected 148 patients complaining only of chronic dry cough for more than eight weeks, 92 patients met the primary selection criteria for cough variant asthma. These 92 patients were given 2 weeks trial of 250 ìgm beclomethasone inhalation twice daily. Seventy nine patients reported almost complete recovery from chronic cough after 2 weeks and were categorized as having CVA. Thirteen patients did not improve and were not categorized as CVA. Conclusion: These findings suggest that cough variant asthma is the most common among the patients with chronic cough not due to any apparent cause. The efficacy of inhaled corticosteroid suggests that early intervention is effective in the treatment of this disease. DOI: http://dx.doi.org/10.3329/jemc.v3i1.13871 J Enam Med Col 2013; 3(1): 29-31


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