Histopathological Examination Profile of Biopsy Specimens in a Remote Tertiary Hospital

Examination of biopsy specimens is necessary to find out the diagnosis. To detect the spectrum of histopathological findings in surgically resected specimens sent in the department of Pathology, Khwaja Yunus Ali Medical College & Hospital (KYAMCH), a rural tertiary hospital in Bangladesh. A total of 1329 specimens from January 2013 to December 2013 were evaluated in this study. Among these, 444 (33.4%) were malignant, 226 (17.0%) were benign, 29 (2.2%) were precancerous, 481 (36.2%) were inflammatory, 14 (1.1%) were tuberculosis, 12 (.9%) were suppurative lesion and 25 (1.9%) were inadequate for diagnosis. The mean age±SE of patients was 42.28±1.68 years. Incidence of malignancy was higher in compare to previous study. It indicates the importance of histopathology for diagnosis and also to exclude malignancy. So any suspicious growth should be excised as early as possible and sent for histopathology. This will help to reduce patients' morbidity and mortality.KYAMC Journal Vol. 5, No.-1, Jul 2014, Page 449-452

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Pattern of upper GlT lesions diagnosed by histopathological examination of endoscopic biopsies in a rural tertiary hospital

KYAMC Journal ◽

10.3329/kyamcj.v9i1.36618 ◽

2018 ◽

Vol 9 (1) ◽

pp. 20-23

Author(s):

Md Mahbur Rashid Sarker ◽

Md Shamim Farooq ◽

Kazi Shihab Uddin ◽

Abu Sharif Mohammad Akramul Islam ◽

Md Zulfikar Ali

Keyword(s):

Histopathological Examination ◽

Tertiary Hospital ◽

Endoscopic Biopsy ◽

Medical College ◽

Biopsy Specimens ◽

Endoscopic Biopsies ◽

Frequent Site ◽

Malignant Lesions ◽

Upper Gastrointestinal ◽

Suspicious Lesions

Background: There are many benign and malignant lesions occur in upper gastrointestinal tract (GIT). Endoscopic biopsy followed by histopathological examination is the gold standard for the diagnosis of these lesions.Objectives: The aim of this study was to determine patterns of benign and malignant lesionsof upper GIT.Materials & Methods: This was a retrospective study carried out in the department of Pathology, Khwaja Yunus Ali Medical College & Hospital (KYAMCH), Sirajgonj from January 2014 to December 2016. All the upper GIT endoscopic biopsy specimens were included in the study.Results: A total of 344 endoscopic biopsies are studied, of which male cases were 234 (68.0%) and female were 110 (32.0%) with M: F of 2.1:1. The age (mean ± sd) of patients was 53.29 ± 15.33 years. Stomach was the most frequent site (77.9%) followed by oesophagus (16.8%) and duodenum (5.3%). The significant diagnostic findings showed malignancies 190(55.2%) followed by inflammation 73 (21.2%) and ulcer 33 (9.6%).Conclusion: For any suspicious lesions in upper GIT, endoscopy followed by histopathological examination should be done for early diagnosis as well as management.KYAMC Journal Vol. 9, No.-1, April 2018, Page 20-23

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Evaluation of Lymph Node Biopsies in a Peripheral Tertiary Hospital

KYAMC Journal ◽

10.3329/kyamcj.v8i1.33874 ◽

2017 ◽

Vol 8 (1) ◽

pp. 49-52

Author(s):

Md Mahbur Rashid Sarker ◽

Md Shamim Farooq ◽

Kazi Shihab Uddin ◽

Sharmin Rashid Tithy

Keyword(s):

Lymph Node ◽

Hodgkin Lymphoma ◽

Clinical Condition ◽

Histopathological Examination ◽

Tertiary Hospital ◽

Metastatic Carcinoma ◽

Medical College ◽

Non Hodgkin Lymphoma ◽

The Mean

Background: Lymphadenopathy is a common clinical condition in Bangladesh and histopathological examination is important for diagnosis.Objectives: The aim of this study was to detect pattern of benign and malignant conditions of lymphadenopathy.Methods: This study was done in the department of Pathology, Khwaja Yunus Ali Medical College & Hospital (KYAMCH), a rural tertiary hospital in Bangladesh. A total of 420 lymph node biopsies from January 2013 to December 2015 were included.Results: Among these, 208 (49.5%) were metastatic carcinoma, followed by non-specific lymphadenitis 116 (27.6%), non-hodgkin lymphoma 48 (11.4%) and tuberculosis 35 (8.3%). The mean age±SD of patients was 44.82±15.42 years. Incidence of malignancy was quite higher in compare to previous studies.Conclusion: In case of any suspicious lymphadenopathy, histopathology should be done for diagnosis and also to exclude malignancy that will help to reduce patients' morbidity and mortality.KYAMC Journal Vol. 8, No.-1, Jul 2017, Page 49-52

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Abnormal Uterine Bleeding in Perimenopausal Age: Different causes and its relation with histopathology

Bangladesh Journal of Medical Science ◽

10.3329/bjms.v13i2.18295 ◽

2014 ◽

Vol 13 (2) ◽

pp. 135-139 ◽

Cited By ~ 1

Author(s):

Nazlima Nargis ◽

Iqbal Karim ◽

Khondaker Bulbul Sarwar

Keyword(s):

Histopathological Examination ◽

Medical Science ◽

Abnormal Uterine Bleeding ◽

Uterine Bleeding ◽

Transvaginal Sonography ◽

Age Group ◽

Histopathological Findings ◽

Medical College ◽

Gynecology And Obstetrics ◽

Study Results

Background: Abnormal uterine bleeding (AUB) is the most common reason for gynecological visits for perimenopausal bleeding and may account for more than 25% of all hysterectomies. Objective: This study was aimed to review the causes of abnormal uterine bleeding in perimenopausal women establishing the correlation with ultrasonographic and histopathological examinations. Study Method: This descriptive study was conducted in the department of gynecology and obstetrics, Ibn Sina Medical College, Dhaka during January to December 2012. Two hundred and eleven women were selected for this study, who admitted into the hospital with abnormal uterine bleeding in perimenopausal age. The clinical, ultrasonographic and histopathological findings of these women were evaluated in this study. Results: Menorrhagia was the major symptom (52.6%) irrespective of age and parity. All these women underwent D&C followed by either medical management or hysterectomy depending upon the diagnosis. The histopathological findings of endometrium were analyzed and confirmed as fibroid uterus (58.28%) and DUB (17.58%) correlated well with transvaginal sonography (TVS) and histopathological examination. Hysterectomy conferred other uterine lesions as adenomyosis (18.71%), endometrial polyp (4.81%) and malignancy (1.06%). Conclusion: Abnormal uterine bleeding in perimenopausal age group is a common but ill-defined entity which needs proper evaluation. Accurate diagnosis of the causative factors of AUB in this age group is of utmost importance so that appropriate management can be established early that leads the minimization of the patients sufferings. DOI: http://dx.doi.org/10.3329/bjms.v13i2.18295 Bangladesh Journal of Medical Science Vol.13(2) 2014 p.135-139

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Endoscopic Biopsies and Histopathological Findings in Diagnosing Chronic Gastrointestinal Disorders in Dogs and Cats

Veterinary Medicine International ◽

10.1155/2020/8827538 ◽

2020 ◽

Vol 2020 ◽

pp. 1-8

Author(s):

Andrzej Rychlik ◽

Ewa Kaczmar

Keyword(s):

Gastrointestinal Tract ◽

Diagnostic Tool ◽

Histopathological Examination ◽

Endoscopic Examination ◽

Gastrointestinal Disorders ◽

Mucosal Biopsy ◽

Histopathological Findings ◽

Biopsy Specimens ◽

Guided Biopsy ◽

Diagnostic Potential

Nowadays, endoscopic examination is a diagnostic tool gaining popularity in the management of gastrointestinal disorders in dogs and cats. Direct accessibility of the lumen of gastrointestinal tract combined with the mucosal biopsy provides a great diagnostic potential. Using endoscopy and endoscopically guided biopsy, one can conduct both macro- and microscopic assessment of lesions and perform many specialist adjunct examinations. Histopathological examination of mucosal biopsy specimens collected from the stomach and intestines allows us to distinguish between types of inflammations and to diagnose ulcerative, polypoid, and cancerous lesions.

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Evaluation of risk of malignancy index in adnexal masses at a tertiary hospital: a prospective study

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20200491 ◽

2020 ◽

Vol 9 (3) ◽

pp. 922

Author(s):

Ritanjali Behera ◽

Paramita Pradhan ◽

Bharati Misra

Keyword(s):

Prospective Study ◽

Gold Standard ◽

Surgical Planning ◽

Tertiary Hospital ◽

Adnexal Masses ◽

Medical College ◽

Risk Of Malignancy ◽

Risk Of Malignancy Index ◽

The Mean ◽

A Prospective Study

Background: The discrimination between benign and malignant adnexal masses is important in deciding clinical management and optimal surgical planning. The aim of the study was to evaluate the effectiveness of risk of malignancy index (RMI) to identify cases with high potential of ovarian malignancy at a tertiary hospital.Methods: This prospective study was conducted over a period of two years from September 2017 to August 2019 at obstetrics and gynecology department of M. K. C. G. Medical College and Hospital, Berhampur. A total case of 130 patients with adnexal masses who underwent surgical treatment were included as histopathological report was taken as gold standard to calculate accuracy of RMI.Results: Of the total masses, 85 (65.4%) were benign and 45 (34.6%) were malignant. The mean age of patients was 41.03±14 years. The best cut off value for the RMI-3 was 225 with highest area under the ROC curve 87%, sensitivity of 75.55%, specificity of 98.82%, PPV of 97.14%, NPV of 88.42% and an accuracy of 90.76%.Conclusions: The present study demonstrated that RMI was a reliable method in detecting malignant ovarian tumors. The RMI is a simple and practically applicable tool in preoperative discrimination between benign and malignant adnexal masses in non-specialized gynecologic departments, particularly in developing countries.

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Patient satisfaction and out-patient services assessment in a tertiary hospital of South Odisha, India

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20171049 ◽

2017 ◽

Vol 4 (2) ◽

pp. 497

Author(s):

J. S. Kshatri ◽

Nivedita Karmee ◽

Sithun Kumar Patro ◽

R. M. Tripathy

Keyword(s):

Patient Satisfaction ◽

Waiting Time ◽

Economic Status ◽

Tertiary Hospital ◽

Medical College ◽

Obstetrics And Gynaecology ◽

The Mean ◽

Out Of Pocket Expenses ◽

First Time ◽

Repeat Visits

Background: The out-patient department of a hospital is for patients who do not require hospitalization but have come for their health needs, either for treatment or for diagnosis. The main objective of the study was to measure the satisfaction levels of the patients attending the OPDs of MKCG medical college.Methods: Data were collected from OPD patients through pre-structured questionnaires in the local languages at the OPD of MKCG Medical College. The data were analysed using SPSS.Results: Out of total 100 patients interviewed, 58 were males and 42 were females. 13% respondents were "highly unsatisfied" with the OPD services where as 65% were "unsatisfied", 15% were "satisfied" and only 7% "highly satisfied". 27% of the participants were from lower socio-economic status (SES), 70% were from middle class and the rest from upper class. 100% of those belonging to upper SES, 80% of middle SES and 70% of lower SES were highly unsatisfied or unsatisfied with OPD services. Most of the patients had come to attend the departments of Medicine (25%), Paediatrics (18%), Surgery (16%) and Obstetrics and Gynaecology (15%). 45% patients were visiting this facility for the first time. 11% of these new patients were Highly satisfied with the services while 31% of repeat patients were either satisfied or highly satisfied. The median waiting time between arrival and consultation was 1 hour. 84% participants had to incur out of pocket expenses. The mean amount spent was Rs. 350. 80% of those who had spent were of the opinion that they had to spend more than what was reasonable.Conclusions: Patient satisfaction was significantly associated with SES, repeat visits, and waiting time between arrival and consultation. Measures to reduce out of pocket expenditure and waiting time may increase satisfaction levels in patients.

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Actinomyces causing chronic tonsillitis: a retrospective study

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20211188 ◽

2021 ◽

Vol 7 (4) ◽

pp. 653

Author(s):

Ravishankara S. ◽

Madhumitha Srinivas ◽

Sreedevi N. T.

Keyword(s):

Retrospective Study ◽

Histopathological Examination ◽

Chronic Tonsillitis ◽

Common Condition ◽

Gram Stain ◽

Palatine Tonsils ◽

Biopsy Specimens ◽

The Mean ◽

Microscopy Examination ◽

Histopathological Evidence

Background: Actinomyces is often overlooked and hence reported as rare infection of palatine tonsils. It can often lead to chronic tonsillitis and can masquerade as oropharyngeal malignancy. Objectives were to estimate the proportion of actinomyces causing chronic tonsillitis using histopathological evidence and to describe the histopathology of tonsillectomy specimens.Methods: Total 33 patients had undergone tonsillectomy in the study period of June 2018 to September 2020. Tonsil biopsy specimens stained with haematoxylin-Eosin stain and gram Stain were evaluated by light microscopy examination for the presence of actinomyces. Results: Total 4 Patients (8 tonsillectomy specimens) had evidence of actinomycosis on histopathological examination constituting 12.12 % of the total specimens examined, the mean age was 17 years (ranging from 5 to 42 years). One of the specimens had unilateral tonsillar cyst which revealed colonies of actinomyces.Conclusions: Actinomycosis of tonsil is a common condition which is usually missed as routine histopathological examination of excised tonsils is not done. Hence, we recommend routine histopathological examination of all tonsillectomy specimens irrespective of age.

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A clinical study of endoscopic management of benign tumors of nasopharynx

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20190775 ◽

2019 ◽

Vol 5 (2) ◽

pp. 430

Author(s):

Devang P. Gupta ◽

Shreya Rai ◽

Shalu Gupta ◽

Nikita Ganvit ◽

Jaydeep Makwana

Keyword(s):

Histopathological Examination ◽

Treatment Options ◽

Surgical Excision ◽

Capillary Hemangioma ◽

Endoscopic Management ◽

Benign Tumors ◽

Nasopharyngeal Angiofibroma ◽

Medical College ◽

The Mean ◽

Benign Tumours

Background: Benign tumors of nasopharynx are extremely rare; seen predominantly in children and young adults. Patients usually present with seemingly innocuous symptoms and an error in judgment can be catastrophic. Aim of our study is to analyse the incidence of these lesions, common presenting features and outcomes of endoscopic management.Methods: This is a retrospective analysis of patients diagnosed to have benign tumours of nasopharynx by histopathological examination in our ENT department of civil hospital, B. J. Medical College, Ahmedabad. The period of study is from January 2016 to January 2018. Forty patients with complete clinical data were identified and included in the study. 33 patients out of 40 (83%) were males and 7 were females (17%). Following surgical excision patients were followed up for a mean period of 2 years. The Clinical profile, investigation modalities, treatment options are being analysed here. Results: Forty patients had undergone surgical excision for tumours arising from the nasopharynx. The mean age was 21.37 years (range 10–43). Thirty three patients were males and seven were females. Indications for resection were juvenile nasopharyngeal angiofibroma in thirty cases, lobular capillary hemangioma in four cases, paraganglioma in two cases, hemangiopericytoma in two cases, and neurofibroma in two cases. There were no significant post-operative complications. Recurrence due to residual lesion was seen in three cases. The mean follow up period was 2 years (range 1-3 years).Conclusions: It is important to note that patients with similar symptoms have varied pathology and thus need for radiological evaluation, JNA is commonest benign nasopharyngeal tumor and surgical approach depends on size and extent of tumor.

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Histopathological Findings in Sudden Cardiac Death: 5-years Autopsy Experience in a Tertiary Hospital in Bandung, Indonesia

Althea Medical Journal ◽

10.15850/amj.v8n2.2324 ◽

2021 ◽

Vol 8 (2) ◽

Author(s):

Gian Nugraha ◽

Nita Novita ◽

Hermin Aminah Usman

Keyword(s):

Sudden Cardiac Death ◽

Sudden Death ◽

Cardiac Death ◽

Coronary Atherosclerosis ◽

Gastrointestinal Disease ◽

Histopathological Examination ◽

Tertiary Hospital ◽

Unexpected Death ◽

Cross Sectional ◽

Histopathological Findings

Background: Sudden death (SD) is a sudden and unexpected death with an unknown cause. However, it has been assummed that the most common causes of sudden deaths are cardiovascular or non-cardiovascular causes such as gastrointestinal disease, respiratory disease, genitourinary disease, epilepsy, and trauma. This study aimed to portray histopathological findings and causes of sudden cardiac death (SCD) cases based on 5 year autopsy experience in a tertiary hospital in Bandung, Indonesia. Methods: This study was a descriptive cross-sectional study exploring causes of SCD from 2015 to 2019 at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia. All medical records with SCD and histopathology findings were retrieved from September to December 2020. Only cases with histopathological examination results were included.Results: SCD was found in 7 of 16 patients with sudden death. Coronary atherosclerosis was the most common (n=4), followed by myocardial infarction (n=2) and ruptured aortic aneurysm (n=1). Myocarditis and calcific aortic valve diseases were not found.Conclusions: In this study, the most common cause of SCD is coronary atherosclerosis, which is identified mainly in older and male patients.

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Prevalence of Adenomyosis in Hysterectomy Specimens Performed at a Tertiary Hospital of Kathmandu, Nepal

Nepal Medical College Journal ◽

10.3126/nmcj.v22i3.32629 ◽

2020 ◽

Vol 22 (3) ◽

pp. 118-122

Author(s):

Kricha Pande ◽

S Koirala ◽

A Giri

Keyword(s):

Incidental Finding ◽

Tertiary Hospital ◽

Cross Sectional Study ◽

Age Group ◽

Cross Sectional ◽

Medical College ◽

Intraepithelial Lesion ◽

The Mean ◽

One Year ◽

Serous Cyst Adenoma

Adenomyosis is a common condition, detected in 15-30% of hysterectomy specimens. It is characterized by the presence of endometrial glands and stroma within the myometrium. The data regarding incidence or incidental finding of adenomyosis in hysterectomy specimen is lacking despite this condition being common and bearing serious implications in symptomatology as well as in infertility. Adenomyosis can be incidental finding in hysterectomy done for other gynecologic pathology as well. Hence, this present study has established the prevalence of adenomyosis as well as it’s association with other uterine pathology in routine hysterectomy specimens. This was a cross sectional study conducted at Nepal Medical College and Teaching Hospital (NMCTH), Kathmandu for a duration of one year (March 2019 to February 2020). Total of 154 hysterectomies were included in the study, out of which 37 cases showed adenomyosis. The prevalence of adenomyosis was 24%. The age group for adenomyosis ranged from 36 years to 52 years with the mean age of 44 ± 4.4 years. The most common pathology other than adenomyosis was leiomyoma (19 cases) followed by two cases of endometriotic cyst, two cases of endometrial polyp, one case of high grade squamous intraepithelial lesion (HSIL), one case of hyperplasia of endometrium with atypia, and one case of serous cyst adenoma of ovary. Thus this study showed that the prevalence of adenomyosis was 24% and was seen higher in the age group of 35-50 years. The most frequent co-pathology in these adenomyosis cases was leiomyoma.

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