scholarly journals Endoscopic Biopsies and Histopathological Findings in Diagnosing Chronic Gastrointestinal Disorders in Dogs and Cats

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Andrzej Rychlik ◽  
Ewa Kaczmar
Keyword(s):  
Gastrointestinal Tract ◽  
Diagnostic Tool ◽  
Histopathological Examination ◽  
Endoscopic Examination ◽  
Gastrointestinal Disorders ◽  
Mucosal Biopsy ◽  
Histopathological Findings ◽  
Biopsy Specimens ◽  
Guided Biopsy ◽  
Diagnostic Potential

Nowadays, endoscopic examination is a diagnostic tool gaining popularity in the management of gastrointestinal disorders in dogs and cats. Direct accessibility of the lumen of gastrointestinal tract combined with the mucosal biopsy provides a great diagnostic potential. Using endoscopy and endoscopically guided biopsy, one can conduct both macro- and microscopic assessment of lesions and perform many specialist adjunct examinations. Histopathological examination of mucosal biopsy specimens collected from the stomach and intestines allows us to distinguish between types of inflammations and to diagnose ulcerative, polypoid, and cancerous lesions.

Neoplastic lesions in the nasal cavities of dogs

2014 ◽  
Vol 17 (2) ◽  
pp. 375-377
Author(s):  
J. Spużak ◽  
M. Jankowski ◽  
K. Kubiak ◽  
K. Glińska-Suchocka ◽  
M. Grzegory ◽  
...  
Keyword(s):  
Nasal Cavity ◽  
Histopathological Examination ◽  
Endoscopic Examination ◽  
Nasal Cavities ◽  
Biopsy Specimens ◽  
Histopathological Evaluation ◽  
Neoplastic Lesions

Abstract This paper aims at evaluating the frequency of nasal cavity tumors in dogs as well as comparing an endoscopic examination with a histopathological evaluation of the collected biopsy specimens. The study was conducted on 68 dogs. During the endoscopic examination, proliferative lesions were recognized in 20 dogs. During the histopathological examination, neoplastic lesions were confirmed in 95% of the dogs in which proliferative lesions were identified in the endoscopic examination. Adenocarcinoma occurred most frequently in the population under study

scholarly journals Colposcopic evaluation of cervical erosion in symptomatic women

2017 ◽  
Vol 6 (6) ◽  
pp. 2207 ◽  
Author(s):  
Pooja Patil ◽  
Priyanka Sharma
Keyword(s):  
Diagnostic Tool ◽  
Pap Smear ◽  
Carcinoma Cervix ◽  
Histopathological Findings ◽  
Speculum Examination ◽  
Cin Iii ◽  
Pruritus Vulvae ◽  
Guided Biopsy ◽  
Menstrual Irregularities

Background: This study was carried out to find the colposcopic findings in the symptomatic patients with cervical erosion and correlate the findings with cytology and histopathology.Methods: All the patients coming to gynaecological OPD with symptoms of white discharge, pruritus vulvae, menstrual irregularities were examined by per speculum examination and all those who had cervical erosion were included in the study and pap smear and colposcopy both were done in all subjects. The colposcopic guided biopsy was done in women with abnormal findings on colposcopy (50 women) and reports were compared. Abnormal colposcopic findings were graded according to Reid’s colposcopic index (RCI).Results: Majority of patients came with the complaint of white discharge per vaginum (55%).Out of 120 patients, 85 women (70.9%) had inflammatory pap smear and 35 women (29.1%)had abnormal pap smear. All patients underwent colposcopic examination and out of 120 patients, 67(55.8%) showed normal colposcopic findings and 50 women (41.6%) had abnormal colposcopic finding and biopsy was taken. 3 women had unsatisfactory colposcopy. Histopathology confirmed 24 (48%) women with CIN I and 12 (24%) CIN II and 6 (12%) CIN III and 2 (4%) women with carcinoma cervix. The colposcopy findings and histopathology correlated in 88%.Conclusions: Colposcopy should be prescribed to all symptomatic patients with cervical erosion as it is a good diagnostic tool for pre-malignant conditions of cervix and correlates well with histopathological findings.

scholarly journals Histopathological Examination Profile of Biopsy Specimens in a Remote Tertiary Hospital

KYAMC Journal ◽  
2017 ◽  
Vol 5 (1) ◽  
pp. 449-452
Author(s):  
Md Mahbur Rashid Sarker ◽  
Md Shamim Farooq ◽  
M Mostaque H Ansari ◽  
Md Shahadat Hossain
Keyword(s):  
Histopathological Examination ◽  
Tertiary Hospital ◽  
Histopathological Findings ◽  
Medical College ◽  
Biopsy Specimens ◽  
The Mean

Examination of biopsy specimens is necessary to find out the diagnosis. To detect the spectrum of histopathological findings in surgically resected specimens sent in the department of Pathology, Khwaja Yunus Ali Medical College & Hospital (KYAMCH), a rural tertiary hospital in Bangladesh. A total of 1329 specimens from January 2013 to December 2013 were evaluated in this study. Among these, 444 (33.4%) were malignant, 226 (17.0%) were benign, 29 (2.2%) were precancerous, 481 (36.2%) were inflammatory, 14 (1.1%) were tuberculosis, 12 (.9%) were suppurative lesion and 25 (1.9%) were inadequate for diagnosis. The mean age±SE of patients was 42.28±1.68 years. Incidence of malignancy was higher in compare to previous study. It indicates the importance of histopathology for diagnosis and also to exclude malignancy. So any suspicious growth should be excised as early as possible and sent for histopathology. This will help to reduce patients' morbidity and mortality.KYAMC Journal Vol. 5, No.-1, Jul 2014, Page 449-452

scholarly journals Abdominal Ultrasonography in Cattle

2016 ◽  
Vol 60 (1) ◽  
pp. 34-40
Author(s):  
K. Munday ◽  
P. Mudron
Keyword(s):  
Gastrointestinal Tract ◽  
Wall Thickness ◽  
Diagnostic Tool ◽  
Abdominal Ultrasound ◽  
Intestinal Wall ◽  
Gastrointestinal Disorders ◽  
Abdominal Ultrasonography ◽  
Colon Wall ◽  
Non Invasive ◽  
Healthy Cattle

Abstract The main goal of this study was to design and propose specific abdominal zones that would contain the gastrointestinal organs in healthy cattle when scanned with trans-abdominal ultrasound. The second goal was to measure the intestinal wall thicknesses of the cranial duodenum, jejunum and colon and to compare healthy cattle intestinal wall thicknesses with pathological cases. All of the six healthy cattle had organs located in the zones proposed. Three of the four pathological cases had organs outside of the zones proposed. The six healthy cattle had an average cranial duodenum wall thickness of 2.45 mm, an average jejunum wall thickness of 1.90 mm and an average colon wall thickness of 3.02 mm. Of the pathological cases, three out of four had intestinal walls that were thicker than that of the average values for the healthy cattle. The thickest intestinal walls were found in the paratuberculosis positive cow. This cow had a cranial duodenum wall thickness of 9.5 mm, a jejunum wall thickness of 4.9 mm and a colon wall thickness of 10.0 mm. In conclusion, trans-abdominal ultrasonography has the potential to be an ideal diagnostic tool for the investigation of the bovine gastrointestinal tract and gastrointestinal disorders such as abscesses, peritonitis and displacement of the abomasum. Trans-abdominal ultrasound also has the potential to be a non-painful, non-invasive tool for the diagnosis of proliferative intestinal inflammations in cattle.

scholarly journals Crush cytology: an expeditious diagnostic tool for gastrointestinal tract malignancy

2021 ◽  
Vol 09 (05) ◽  
pp. E735-E740
Author(s):  
Pankaj Desai ◽  
Mayank Kabrawala ◽  
Chintan Patel ◽  
Priya Arora ◽  
Rajiv Mehta ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Diagnostic Accuracy ◽  
Predictive Value ◽  
Histopathological Examination ◽  
Malignant Lesion ◽  
Cost Effective ◽  
Endoscopic Examination ◽  
Cross Sectional ◽  
Gastrointestinal Malignancies ◽  
Malignant Lesions

Abstract Background and study aims Crush cytology is a simple and rapid method used for diagnosis of central nervous system lesions. We have evaluated the diagnostic accuracy of crush cytology for gastrointestinal tract lesions. Patients and methods This was a prospective, cross-sectional, single center study, conducted on the patients who had suspected malignant lesions between August 2018 and March 2020. The crush cytologic diagnoses were correlated with histology to determine the diagnostic accuracy. Results During the period of interest, a total of 451 patients (26.4 % esophagus & GE junction, 16.6 % stomach, 5.9 % ampulla & duodenum, and 50.9 % colorectal) had a suspected malignant lesion on endoscopic examination. Histology confirmed 92.9 % cases as malignant lesions and 7.1 % as nonmalignant. On crush cytology, 84.5 % were positive for malignancy, 8.9 % were negative for malignancy and 6.6 % were reported as suspicious for malignancy. The overall sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of crush cytology were 97.3 %, 90 %, 99.2 %, 72.5 % and 96.9 %, respectively. Conclusions Crush cytology is a highly sensitive, specific, rapid and cost effective technique to diagnose gastrointestinal malignancies in endoscopically suspected malignant lesions. However, it cannot entirely substitute histopathological examination for definite tumor typing, grading, confirming invasion and in cases in which cytology is suspicious. Crush cytology is an added asset to the histology to maximize diagnostic accuracy and accelerating decision making for the management of lesions.

Evaluation of Breast Lumps by Ultrasound and Correlation with Histological Findings

2020 ◽  
Vol 23 (1) ◽  
pp. 10-12
Author(s):  
Nelema Jahan ◽  
Md. Mamunur Rahman ◽  
Mohammad Shahidul Alam ◽  
Md Saiful Islam
Keyword(s):  
Histopathological Examination ◽  
Breast Diseases ◽  
Histopathological Study ◽  
Common Symptom ◽  
Breast Lump ◽  
Histopathological Findings ◽  
Malignant Breast ◽  
Breast Lumps ◽  
One Year ◽  
A Prospective Study

Background: A breast lump is the most common symptom associated with both benign and malignant breast diseases. Therefore, a distinction of benign from malignant lump is of importance for proper management. Though a definitive diagnosis is possible with imaging for all the lesions, histopathological study is proven essential for confirming the diagnosis. Objective: The objective of this study was to evaluate the role of USG and histopathological findings of different breast lump in diagnosis and their comparison. Methods: A prospective study was conducted over a period of one year from January 2017 to December 2017. A total of 116 patients were included in this study. All breast lumps underwent surgery and the ultrasound findings of these lumps were compared with the histopathological findings. Data were collected from these patients by a preformed questionnaire and finally the data were analyzed. Results: Out of 116 patients only 21 cases were reported as malignant in ultrasound report but histopathology revealed 31 malignant patients. On histopathological examination 10 benign cases turned out to be malignant. Conclusion: The present study was undertaken to evaluate in diagnosing breast mass lesions individually by ultrasound and compared with histopathology for definitive management of a patient. Journal of Surgical Sciences (2019) Vol. 23 (1) : 10-12

Esophageal Adenocarcinoma with Enteroblastic Differentiation Arising in Ectopic Gastric Mucosa in the Cervical Esophagus: a Case Report and Literature Review

2017 ◽  
Vol 26 (2) ◽  
pp. 193-197 ◽  
Author(s):  
Ryosuke Gushima ◽  
Rei Narita ◽  
Takashi Shono ◽  
Hideaki Naoe ◽  
Takashi Yao ◽  
...  
Keyword(s):  
Gastric Mucosa ◽  
Esophageal Adenocarcinoma ◽  
Histopathological Examination ◽  
Narrow Band Imaging ◽  
Carbohydrate Antigen ◽  
Endoscopic Examination ◽  
Ectopic Gastric Mucosa ◽  
Tubular Adenocarcinoma ◽  
Positron Emission ◽  
Elevated Lesion

Background: Adenocarcinoma with enteroblastic differentiation is a subtype of alpha-fetoprotein (AFP) producing adenocarcinoma. This type of tumor is associated with a poor prognosis and is prone to metastasize. Esophageal adenocarcinoma with enteroblastic differentiation is extremely rare.Case presentation: The patient was a 65-year-old woman who was referred to our hospital with dysphagia. Endoscopic examination revealed an elevated lesion 20mm in diameter at 17cm from the upper incisors. Endoscopic submucosa dissection (ESD) was performed and histopathological examination revealed tubular adenocarcinoma composed of cuboidal cells with clear cell cytoplasm. Immunohistochemical stain was diffusely positive for Sall-like protein 4 (SALL4) and weakly positive for AFP and glypican 3. From this result, we diagnosed esophageal adenocarcinoma with enteroblastic differentiation. The patient is still alive without recurrence of cancer 40 months after ESD.Conclusion: To our knowledge, this is the first report to undergo ESD for esophageal adenocarcinoma with enteroblastic differentiation arising from ectopic gastric mucosa in the esophagus.Abbreviations: AFP: alfa-fetoprotein; CA19-9: carbohydrate antigen 19-9; CEA: carcinoembryonic antigen; ESD: endoscopic submucosal dissection; EUS: endoscopic ultrasound; FDG-PET: [18F] fluorodeoxyglucose positron emission tomography; ME: magnifying endoscopy; NBI: narrow band imaging; SALL 4: Sall-like protein 4; SCC: squamous cell carcinoma antigen.

scholarly journals Polypoidal lesions of the gastrointestinal tract

2020 ◽  
Vol 10 (1) ◽  
pp. 1625-1629
Author(s):  
Palzum Sherpa ◽  
Abhimanyu Jha ◽  
Sudhamshu Koirala ◽  
Rojan Ghimire
Keyword(s):  
Gastrointestinal Tract ◽  
Large Intestine ◽  
Hyperplastic Polyp ◽  
Histopathological Examination ◽  
Biological Behavior ◽  
Research Centre ◽  
Chi Square ◽  
Neoplastic Lesions ◽  
Chi Square Test ◽  
Conventional Adenoma

Background: With increasing usage of endoscopic procedures, gastrointestinal polypoidal lesions are commonly encountered specimens. Histopathological examination is crucial as biological behavior is dependent on its pathological nature. Materials and Methods: A retrospective descriptive study performed in Pathology department, Om Hospital and Research Centre from January 2017 to June 2019. The study included lesions received as polyp or polypoidal lesions of gastrointestinal tract for histopathological examination. Data was analysed using SPSS version 17.0. Gender, number and site were analysed using Chi square test to evaluate its association with neoplastic nature. Correlation with age and size was tested with Pearson’s correlation coefficient. Results: Among 150 cases of gastrointestinal tract polypoidal lesions, 58% were seen in male and 42% in female. Hyperplastic polyp and conventional adenoma were the commonest non-neoplastic and neoplastic lesions respectively. The age of patients ranged from 7 to 84 years with a mean age of 50 years. Rectosigmoid region was the commonest site. 134 patients had single and 16 had multiple polypoidal lesions. Most polypoidal lesion had size <1 cm. Gender, age, number and size showed no correlation with neoplastic nature. A significant association was found with site with notably higher number of neoplastic lesions in large intestine. Conclusion: A spectrum of histological types of polypoidal lesions were found in Gastrointestinal tract, most frequently in colorectal region. Hyperplastic polyp and adenomatous polyp were the commonest non-neoplastic and neoplastic lesions respectively. A notably higher number of polypoidal lesions in the large intestine were found to be neoplastic in nature.

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