scholarly journals Cardiac Complications of Hyperthyroidism: Echocardiographic Evaluation of 69 Hyperthyroid Patients

1970 ◽  
Vol 17 (1) ◽  
pp. 6-9 ◽  
Author(s):  
SM Ansari ◽  
S Haider ◽  
MA Awal ◽  
N Khanam ◽  
AB Siddique
Keyword(s):  
Thyroid Hormones ◽  
Clinical Diagnosis ◽  
Chest Radiography ◽  
Cardiac Complications ◽  
Cardiac Pathology ◽  
Echocardiographic Evaluation ◽  
Different Types ◽  
Cardiac Evaluation ◽  
Hyperthyroid Patients

Echocardiography were done on 69 patients suffering from hyperthyroidism. All of them presented with palpitation and tremor. Clinical diagnosis was confirmed by radioimmunoassay of thyroid hormones. Echocardiography as well as Electrocardiography and chest radiography were done in all of them. Forty seven patients showed different types of cardiac pathology, results of which are demonstrated in details. We conclude that thorough cardiac evaluation is necessary in all hyperthyroid patients.   doi: 10.3329/taj.v17i1.3481 TAJ 2004; 17(1) : 6-9

The CSF p-tau181/Aβ42 Ratio Offers a Good Accuracy “In Vivo” in the Differential Diagnosis of Alzheimer’s Dementia

2019 ◽  
Vol 16 (7) ◽  
pp. 587-595 ◽  
Author(s):  
Roberto Santangelo ◽  
Alessandro Dell'Edera ◽  
Arianna Sala ◽  
Giordano Cecchetti ◽  
Federico Masserini ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Clinical Diagnosis ◽  
Fdg Pet ◽  
Amyloid Β ◽  
Cost Effective ◽  
Daily Clinical Practice ◽  
Different Types ◽  
Experimental Trials ◽  
Csf Findings

Background: The incoming disease-modifying therapies against Alzheimer’s disease (AD) require reliable diagnostic markers to correctly enroll patients all over the world. CSF AD biomarkers, namely amyloid-β 42 (Aβ42), total tau (t-tau), and tau phosphorylated at threonine 181 (p-tau181), showed good diagnostic accuracy in detecting AD pathology, but their real usefulness in daily clinical practice is still a matter of debate. Therefore, further validation in complex clinical settings, that is patients with different types of dementia, is needed to uphold their future worldwide adoption. Methods: We measured CSF AD biomarkers’ concentrations in a sample of 526 patients with a clinical diagnosis of dementia (277 with AD and 249 with Other Type of Dementia, OTD). Brain FDG-PET was also considered in a subsample of 54 patients with a mismatch between the clinical diagnosis and the CSF findings. Results: A p-tau181/Aβ42 ratio higher than 0.13 showed the best diagnostic performance in differentiating AD from OTD (86% accuracy index, 74% sensitivity, 81% specificity). In cases with a mismatch between clinical diagnosis and CSF findings, brain FDG-PET partially agreed with the p-tau181/Aβ42 ratio, thus determining an increase in CSF accuracy. Conclusions: The p-tau181/Aβ42 ratio alone might reliably detect AD pathology in heterogeneous samples of patients suffering from different types of dementia. It might constitute a simple, cost-effective and reproducible in vivo proxy of AD suitable to be adopted worldwide not only in daily clinical practice but also in future experimental trials, to avoid the enrolment of misdiagnosed AD patients.

Red-cell 2,3-diphosphoglycerate in patients with hyperthyroidism

1980 ◽  
Vol 93 (4) ◽  
pp. 424-429 ◽  
Author(s):  
J. L. Alvarez-Sala ◽  
M. A. Urbán ◽  
J. J. Sicilia ◽  
A. J. Diaz Fdez ◽  
F. Fdez Mendieta ◽  
...  
Keyword(s):  
Thyroid Hormones ◽  
Control Group ◽  
Red Cell ◽  
Oxygen Dissociation Curve ◽  
Dissociation Curve ◽  
Oxygen Dissociation ◽  
The Right ◽  
Serum Thyroid Hormones ◽  
Hyperthyroid Patients ◽  
2,3 Dpg

Abstract. In 21 hyperthyroid female patients studied on 29 occasions, high levels of red-cell 2,3-diphosphoglycerate (2,3-DPG) have been found (5.75 ± 0.7 mm) which, compared to a euthyroid control group (4.88 ± 0.4 mm), could not be accounted for by differences in haematocrit, haemoglobin or phosphataemia. A significant correlation was found (P < 0.05) between serum thyroid hormones and the 2,3-DPG concentration in the hyperthyroid patients. Eight of these patients were reexamined after treatment and normalization of thyroid function, showed a regression to normal 2,3-DPG values (4.81 ± 0.6 mm) which could not be attributed to variations in haematocrit, haemoglobin or phosphataemia either. We therefore deduce that the shift to the right in the haemoglobin oxygen dissociation curve observed in patients of this type may be due to an increase in the red-cell 2,3-DPG content.

scholarly journals Epidemiological Distribution and Subtype Analysis of Premenstrual Dysphoric Disorder Syndromes and Symptoms Based on TCM Theories

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Mingqi Qiao ◽  
Peng Sun ◽  
Haijun Wang ◽  
Yang Wang ◽  
Xianghong Zhan ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Clinical Diagnosis ◽  
Premenstrual Dysphoric Disorder ◽  
Diagnosis And Treatment ◽  
Epidemiological Investigation ◽  
Different Types

We performed an epidemiological investigation of subjects with premenstrual dysphoric disorder (PMDD) to identify the clinical distribution of the major syndromes and symptoms. The pathogenesis of PMDD mainly involves the dysfunction of liver conveyance and dispersion. Excessive liver conveyance and dispersion are associated with liver-qi invasion syndrome, while insufficient liver conveyance and dispersion are expressed as liver-qi depression syndrome. Additionally, a nonconditional logistic regression was performed to analyze the symptomatic features of liver-qi invasion and liver-qi depression. As a result of this analysis, two subtypes of PMDD are proposed, namely, excessive liver conveyance and dispersion (liver-qi invasion syndrome) and insufficient liver conveyance and dispersion (liver-qi depression syndrome). Our findings provide an epidemiological foundation for the clinical diagnosis and treatment of PMDD based on the identification of different types.

scholarly journals TSH Influences Serum Leptin Levels Independent of Thyroid Hormones in Hypothyroid and Hyperthyroid Patients

2005 ◽  
Vol 52 (2) ◽  
pp. 213-217 ◽  
Author(s):  
Aysin OGE ◽  
Firat BAYRAKTAR ◽  
Fusun SAYGILI ◽  
Engin GUNEY ◽  
Serap DEMIR
Keyword(s):  
Thyroid Hormones ◽  
Serum Leptin ◽  
Hyperthyroid Patients

To the problem of pregnant women's cholestasis

2021 ◽  
Vol 50 (2) ◽  
pp. 90-93
Author(s):  
T. V. Timofeeva ◽  
N. N. Petrishchev ◽  
M. S. Zainulina ◽  
I. N. Mukhina
Keyword(s):  
Liver Disease ◽  
Pregnant Women ◽  
Chronic Liver Disease ◽  
Clinical Diagnosis ◽  
Chronic Liver ◽  
Complex Concept ◽  
Different Types ◽  
Management Method ◽  
Pathological Pregnancy

Liver disease andpregnancy usually aggravates each other. Its rather difficult to differentiate pregnant womens cholestasis from gestosis accompanied with chronic liver disease preceding pregnancy. 60 pregnant women were examined, the first group with cholestatic hepatosis, the second group with gestosis and liver disease. The practical aim o f the study was to choose righttactics o f pregnancy management, method and date o f confinement.Pregnant womens hepatosis turned out to be a complex concept: it may embrace different types o f pathological pregnancy under the single clinical diagnosis.

scholarly journals Incidental Finding of Giant Coronary Artery Aneurysms Successfully Treated with Medical Therapy

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Rony Shammas ◽  
Prasanna Sengodan ◽  
Assad Movahed
Keyword(s):  
Coronary Artery ◽  
Medical Therapy ◽  
Chest Radiography ◽  
Incidental Finding ◽  
Lower Lobe ◽  
Signs And Symptoms ◽  
Coronary Artery Aneurysms ◽  
Coronary Aneurysms ◽  
Cardiac Evaluation

We report a case of a 30-year-old male who presented with signs and symptoms of respiratory infection with left lower lobe consolidation and cardiomegaly on a chest radiography. The presence of cardiomegaly lead to further cardiac evaluation revealing giant coronary aneurysms. The patient was treated conservatively with Coumadin and aspirin and has done well at four years of follow-up.

Liver Transplantation in Patients With Cardiac Disease

2017 ◽  
Vol 22 (2) ◽  
pp. 111-121 ◽  
Author(s):  
Christopher L. Wray
Keyword(s):  
Cardiovascular Disease ◽  
Liver Transplantation ◽  
Perioperative Period ◽  
Cardiovascular Complications ◽  
Adverse Outcomes ◽  
Treatment Modalities ◽  
Cardiac Complications ◽  
Major Step ◽  
Cardiac Evaluation ◽  
The Impact

Liver transplantation (LT) is a unique surgical procedure that has major hemodynamic and cardiovascular implications. Recently, there has been significant interest focused on cardiovascular issues that affect LT patients in all phases of the perioperative period. The preoperative cardiac evaluation is a major step in the selection of LT candidates. LT candidates are aging in concordance with the general population; cardiovascular disease and their risk factors are highly associated with older age. Underlying cardiovascular disease has the potential to affect outcomes in LT patients and has a major impact on candidate selection. The prolonged hemodynamic and metabolic instability during LT may contribute to adverse outcomes, especially in patients with underlying cardiovascular disease. Cardiovascular events are not unusual during LT; transplant anesthesiologists must be prepared for these events. Advanced cardiovascular monitoring techniques and treatment modalities are now routinely used during LT. Postoperative cardiovascular complications are common in both the early and late posttransplant periods. The impact of cardiac complications on posttransplant mortality is well recognized. Emerging knowledge regarding cardiovascular disease in LT patients and its impact on posttransplant outcomes will have an important role in guiding the future perioperative management of LT patients.

scholarly journals Plasma D-Dimer Level in Different Types of Acute Ischaemic Stroke Patients: Experience at a Tertiary Hospital in Dhaka City

2019 ◽  
Vol 5 (1) ◽  
pp. 13-17
Author(s):  
Paritosh Kumar Sarkar ◽  
Anwar Israil ◽  
Mohammad Sayeed Hassan ◽  
Abu Nayeem ◽  
Md Azharul Hoque ◽  
...  
Keyword(s):  
Internal Medicine ◽  
Ischemic Stroke ◽  
Ischaemic Stroke ◽  
Clinical Diagnosis ◽  
Acute Ischaemic Stroke ◽  
Stroke Patients ◽  
College Hospital ◽  
Medical College ◽  
Different Types ◽  
D Dimer

Background: Plasma D-Dimer is a biomarker of thrombo-embolism. Objective: The purpose of the present study was to see the plasma D-dimer level in different types of acute ischaemic stroke patients. Methodology: This cross-sectional study was conducted in the Department of Neurology & Department of Internal Medicine at Dhaka Medical College Hospital, Dhaka, Bangladesh from July 2010 to June 2012 for a period of two (02) years. Patients with ischemic stroke with history within 7 days attending in the stroke clinic of Department of Neurology or admitted in the Department of Neurology and Internal Medicine through the outpatient and emergency Department of Dhaka Medical College Hospital (DMCH) were selected as study population for this study. Analysis of plasma D-Dimer was done in the Department of Hematology of DMCH.b Result: A total of 50 cases were recruited for this study. There were 24.0% lacunar infarcts, 40.0% atherothrombotic and 36.0% embolic infarcts in the study group. Highest level of plasma D-Dimer was observed in embolic (1700±964 ηg/ml) followed by atherothrombotic group (536±234 ηg/ml). The plasma D-Dimer was lowest (100±0 ηg/ml) in lacunar group. Concentration of Plasma D-Dimer showed significant correlation with clinical diagnosis in different subtypes of ischemic stroke (r=0.902; p=0.001) and also with risk factors, example, diabetes (r=0.319; p=0.012) and valvular heart disease (r=0.281; p=0.024), but no significant correlation with age, hypertension, hyperlipidaemia and smoking. Conclusion: In conclusion plasma D-Dimer is an important bio-marker in the clinical diagnosis and subtypes of ischemic stroke patients. Journal of National Institute of Neurosciences Bangladesh, 2019;5(1): 13-17

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