scholarly journals Adherence Improvement in Glaucoma Patients: Effects of Educational Intervention Using an Eye Drop Chart

2021 ◽  
Vol 62 (12) ◽  
pp. 1617-1625
Author(s):  
Woo Seok Choi ◽  
Jong Heon Kim ◽  
Chang Hoon Lee ◽  
Chong Eun Lee ◽  
Sam Seo
Keyword(s):  
Intraocular Pressure ◽  
Educational Intervention ◽  
Pressure Control ◽  
Demographic Characteristics ◽  
Control Group ◽  
Eye Drops ◽  
Supplementary Education ◽  
Adherence Score ◽  
Education Group ◽  
Multicenter Prospective Study

Purpose: To evaluate the effects of an educational intervention using an eye drop chart and supplementary education on glaucoma patients’ adherence.Methods: In this multicenter prospective study, medically treated glaucoma patients were educated on the administration of eye drops using an eye drop chart. At the time of recruitment, all of the patients completed a questionnaire on demographic characteristics and adherence. Three months after the initial educational intervention, the patients were randomly divided into two groups: an education group and a control group. The education group received supplementary education. Immediately thereafter and at 6 months, all of the patients completed the questionnaire on adherence again. Changes in instillation behavior, the relationship between the adherence score and demographic characteristics, and factors contributing to an improvement in adherence and intraocular pressure were then analyzed.Results: The adherence scores were significantly higher in patients with fewer medications, a higher annual income and higher educational level, and an urban residence (p = 0.038, p = 0.033, p = 0.041 and p = 0.047, respectively). Education on the administration of eye drops and use of the eye drop chart improved adherence scores from 23.05 ± 3.52 to 21.30 ± 3.95 (p = 0.021) and significantly reduced the average intraocular pressure from 14.3 ± 2.9 to 12.4 ± 3.1 mmHg (p < 0.001). Working indoors (odds ratio [OR] = 5.47, p = 0.032) and supplementary education at 3 months (OR = 4.53, p = 0.030) were also correlated with improved adherence.Conclusions: An eye drop chart is an effective tool for improving adherence and intraocular pressure control in glaucoma patients. Improvement in adherence was especially notable in patients whose work predominantly involved indoor activity. The effectiveness of the eye drop chart was improved by supplementary education.

scholarly journals Topical Treatment of Elevated Intraocular Pressure in Patients with Graves’ Ophthalmopathy

2020 ◽  
Author(s):  
Magdalena Gumińska ◽  
Roman Goś ◽  
Janusz Śmigielski ◽  
Michał Szymon Nowak
Keyword(s):  
Intraocular Pressure ◽  
Corticosteroid Therapy ◽  
Topical Treatment ◽  
Final Visit ◽  
Control Group ◽  
Eye Drops ◽  
Systemic Corticosteroids ◽  
Subgroup Ii ◽  
Elevated Intraocular Pressure ◽  
Study Participants

Purpose: The evaluation of the efficacy of topical hypotensive treatment and/or systemic corticosteroids therapy in patients with elevated intraocular pressure and Graves&rsquo; orbitopathy (GO). Methods: 172 eyes in 86 individuals with duration of GO &ge; 3 months, intraocular pressure in either eye &ge; 25.0 mmHg and GO ranked &ge; 3 at least in one eye in modified CAS form, were included. The study subjects were divided into three treatment subgroups: subgroup I was administered latanoprost QD; subgroup II was administered a combined preparation of brimonidine and timolol BID; subgroup III was the control group, not receiving any topical hypotensive treatment. All the study participants received systemic treatment &ndash; intravenous corticosteroid therapy at the same dose, according to the EUGOGO guideline Results: On the final visit, the mean IOP value was significantly lower in all treatment subgroups comparing to the initial values. In both subgroups receiving topical treatment the IOP reduction was higher than in the control group receiving systemic corticosteroids only. However, the latanoprost eye drops decreased intraocular pressure more effectively than drops containing brimonidine and timolol. Conclusion: Topical ocular hypotensive treatment is effective in reducing intraocular pressure in GO and decreases intraocular pressure more effectively than systemic corticosteroid therapy alone.

Intraocular light scatter in patients on topical intraocular pressure–lowering medication

2018 ◽  
Vol 28 (6) ◽  
pp. 652-661
Author(s):  
Francisco Pérez-Bartolomé ◽  
Jose María Martínez de la Casa ◽  
Pedro Arriola-Villalobos ◽  
Cristina Fernández-Pérez ◽  
Julián García-Feijoó
Keyword(s):  
Intraocular Pressure ◽  
Light Scattering ◽  
Treatment Duration ◽  
Control Group ◽  
Eye Drops ◽  
Light Scatter ◽  
Non Invasive ◽  
Pressure Lowering ◽  
Breakup Time ◽  
Objective Scatter Index

Purpose: To quantify ocular light scattering in patients under treatment with intraocular pressure–lowering eye-drops. Methods: In this prospective, observational, cross-sectional case series study, 160 eyes of 160 patients with primary open angle glaucoma or primary ocular hypertension were consecutively recruited from our Glaucoma Department over 7 months. In total, 46 eyes of 46 healthy volunteers matched for age and sex served as the control group. The variables recorded in a single visit were as follows: drug and number of drops per day, treatment duration, OXFORD corneal staining grade, lower tear meniscus height as measured by spectral domain optical coherence tomography, ocular redness and non-invasive tear breakup time measured with the Oculus Keratograph 5M, ocular surface disease index questionnaire score and objective scatter index through a double-pass technique (Optical Analysis System II). Results: Objective scatter index was higher in the patient group (3.1, interquartile range = 1.8–5.47) than in the control group (1.95; interquartile range = 0.7–5; p = 0.017). In a multiple linear regression model, non-invasive tear breakup time was identified as the most influential variable on light scatter (mean ratio = −1.015; p = 0.003; 95% confidence interval = −1.025 to −1.005). No correlation with objective scatter index was observed for number of daily eye-drops, preservative concentration or treatment duration. Conclusion: Participants on anti-glaucoma medication showed a significantly higher objective scatter index than control group individuals. In the treated patient group, a lower non-invasive tear breakup time was associated with a higher objective scatter index. This suggests that lubricating eye-drops to improve tear breakup time could also improve vision quality in these patients by diminishing light scattering.

scholarly journals Topical Treatment of Elevated Intraocular Pressure in Patients with Graves’ Orbitopathy

2020 ◽  
Vol 17 (24) ◽  
pp. 9331
Author(s):  
Magdalena Gumińska ◽  
Roman Goś ◽  
Janusz Śmigielski ◽  
Michał S. Nowak
Keyword(s):  
Intraocular Pressure ◽  
Corticosteroid Therapy ◽  
Topical Treatment ◽  
Final Visit ◽  
Control Group ◽  
Eye Drops ◽  
Systemic Corticosteroids ◽  
Elevated Intraocular Pressure ◽  
Graves Orbitopathy ◽  
Study Participants

Purpose: In this study, we evaluated the efficacy of topical hypotensive treatment and/or systemic corticosteroids therapy in patients with elevated intraocular pressure and Graves’ orbitopathy (GO). Methods: We included 172 eyes in 86 individuals with duration of GO ≥ 3 months, intraocular pressure in either eye ≥ 25.0 mmHg, and GO ranked ≥ 3 at least in one eye in modified CAS form. The study subjects were divided into three treatment subgroups: subgroup I was administered latanoprost once a day; subgroup II was administered a combined preparation of brimonidine and timolol BID; subgroup III was the control group, not receiving any topical hypotensive treatment. All the study participants received systemic treatment, intravenous corticosteroid therapy at the same dose, according to the European Group of Graves’ Orbitopathy (EUGOGO) guideline. Results: On the final visit, the mean IOP value was significantly lower in all treatment subgroups compared to the initial values. In both subgroups receiving topical treatment, the IOP reduction was higher than in the control group receiving systemic corticosteroids only. However, the latanoprost eye drops decreased intraocular pressure more effectively than drops containing brimonidine and timolol. Conclusion: Topical ocular hypotensive treatment is effective in reducing intraocular pressure in GO and decreases intraocular pressure more effectively than systemic corticosteroid therapy alone.

scholarly journals Phacoemulsification after Trabeculectomy in Uveitis Associated with Vogt-Koyanagi-Harada Disease: Intermediate-Term Visual Outcome, IOP Control and Trabeculectomy Survival

2021 ◽  
Author(s):  
Faisal A. Almobarak ◽  
Ali Alharbi ◽  
Ibrahim Aljadaan ◽  
Hasan Aldhibi
Keyword(s):  
Visual Acuity ◽  
Intraocular Pressure ◽  
Cataract Surgery ◽  
Visual Outcome ◽  
Pressure Control ◽  
Control Group ◽  
Study Group ◽  
Safe Procedure ◽  
Patient Counselling ◽  
And Control

Abstract PurposeTo evaluate the visual outcome, intraocular pressure control and survival of trabeculectomy after phacoemulsification in eyes with prior trabeculectomy in uveitis associated with Vogt-Koyanagi-Harada disease (VKH).DesignRetrospective comparative study.MethodsEyes with uveitic glaucoma associated with VKH who underwent mitomycin C (MMC)-enhanced trabeculectomy were included. Eyes were divided into two groups: the first study group included eyes that later underwent cataract surgery in the form of phacoemulsification, and the second control group included eyes that did not have cataract surgery. The main outcome measures were changes in the visual acuity, intraocular pressure (IOP), the number of antiglaucoma medications, IOP control and trabeculectomy survival. ResultsThere were no significant differences in the final visual acuity (0.78 (±0.9) and 0.92 (±1.1), p=0.80)) nor IOP (14.21 mmHg (±5.8) and 12.16 mmHg (±6.1), p=0.29), but there was a difference in the antiglaucoma medications (1.58 (±1.5) and 0.53 (±1.0), p=0.02) between the study and control group, respectively. There was no difference in the overall trabeculectomy survival (p=0.381, Log Rank), but more eyes in the study group converted to qualified success after phacoemulsification and required more medications to control the IOP.ConclusionPhacoemulsification after trabeculectomy seems to be a safe procedure in eyes with combined vision threatening complications of VKH, although the visual improvement was limited. Nevertheless, more medications were required to control the IOP, thereby affecting IOP control; but such medication did not affect trabeculectomy survival. Therefore, patient counselling before surgery is essential.

Xen Gel Stent as a minimally invasive option for intraocular pressure control after DSAEK: A case study

2020 ◽  
pp. 112067212096033
Author(s):  
Myrta Lippera ◽  
Stefano Lippera ◽  
Piero Ferroni ◽  
Giuseppe Pallotta ◽  
Sabrina Morodei ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Minimally Invasive ◽  
Medical Treatment ◽  
Invasive Procedure ◽  
Pressure Control ◽  
Positive Outcome ◽  
Bullous Keratopathy ◽  
Corneal Transplant ◽  
Eye Drops

Purpose: This case study describes the implantation of a Xen45 Gel Stent in a patient that had previously undergone Descemet stripping automated endothelial keratoplasty (DSAEK). Glaucoma might worsen after corneal transplant, and while medical treatment is the first-line therapy to achieve intraocular pressure (IOP) control, a surgical approach is required when medication does not reach the target IOP. Methods: In 2017, the patient underwent treatment in both eyes with ocular hypotensive eye drops for pseudoexfoliative (PXF) glaucoma. In May 2017, DSAEK was performed on the right eye because of the presence of a pseudophakic bullous keratopathy. An increase in IOP, resistant to medical treatment, was observed after the corneal transplant. In November 2017, a Xen45 Gel Stent was implanted. Results: The patient had a positive outcome with a Xen45 Gel Stent implant in surgical glaucoma treatment after DSAEK. The case demonstrated excellent postoperative IOP control, stable vision and a healthy ocular graft at short-term and long-term follow-ups. Conclusion: Studies with larger numbers of patients in this particular form of therapy are required. Nevertheless, Xen45 Gel Stent implantation appears to be a promising option in preventing or limiting glaucoma in patients who have previously undergone DSAEK. It is a brief, minimally invasive procedure with reduced postoperative inflammation, faster visual recovery and a lower risk of graft damage or hypotony, even in the case of PXF glaucoma.

scholarly journals The Effect of Rebamipide on Ocular Surface Disorders Induced by Latanoprost and Timolol in Glaucoma Patients

2015 ◽  
Vol 2015 ◽  
pp. 1-5 ◽  
Author(s):  
Naoto Tokuda ◽  
Yasushi Kitaoka ◽  
Akiko Matsuzawa ◽  
Junsuke Miyamoto ◽  
Shinsuke Sakae ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Ocular Surface ◽  
Barrier Function ◽  
Epithelial Barrier ◽  
Control Group ◽  
Eye Drops ◽  
Drug Induced ◽  
Epithelial Barrier Function ◽  
Corneal Epithelial ◽  
Significant Difference

Purpose. To examine the efficacy of ophthalmic rebamipide suspensions on ocular surface disorders induced by antiglaucoma eye drops.Patients and Methods. Forty eyes of 40 patients receiving latanoprost (0.005%) and timolol (0.5%) were included in this randomized prospective study. The patients were randomly divided into two groups (n= 20): the rebamipide-treated group and control group. Changes in intraocular pressure, tear film break-up time (TBUT), and corneal epithelial barrier function were evaluated at baseline, 4 weeks, and 8 weeks after rebamipide administration. Furthermore, superficial punctate keratopathy severity was evaluated by scoring the lesion area and density.Results. There was no significant difference in intraocular pressure before and after rebamipide treatment. However, corneal epithelial barrier function improved significantly 4 and 8 weeks after rebamipide treatment. TBUT was partially, but significantly, increased (P= 0.02) 8 weeks after rebamipide treatment, whereas no significant change was observed at 4 weeks. Additionally, a significant decrease in area and density of keratopathy was observed 8 weeks after rebamipide treatment but not at 4 weeks. The control group showed no significant difference compared to baseline.Conclusions. Our data suggests that rebamipide treatment may reduce the occurrence of drug-induced ocular surface disorder.

scholarly journals Fixed combination bimatoprost-timolol in prevention of ocular hypertension after phacoemulsification of uncomplicated cataract

2016 ◽  
Vol 9 (2) ◽  
pp. 69-73
Author(s):  
Igor’ B Alekseev ◽  
Bella N Khatsukova ◽  
Marija M Soshina ◽  
Nadezhda I Samokhina ◽  
Julija A Nam ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Cataract Surgery ◽  
Ocular Hypertension ◽  
Postoperative Period ◽  
Fixed Combination ◽  
Corneal Edema ◽  
Main Group ◽  
Control Group ◽  
Surgical Trauma ◽  
Eye Drops

To date, cataract surgery development aims at minimizing surgical trauma in order to achieve a quicker rehabilitation. However, one of the severe complications of cataract surgery is increased intraocular pressure due to the inflammatory response, the so-called reactive syndrome that occurs in the early postoperative period. Aim of the study was to evaluate the efficacy of a fixed combination of bimatoprost and timolol (Ganfort) eye drops in prevention of ocular hypertension and corneal edema after ultrasonic phacoemulsification. Materials and methods. The study included 60 patients (60 eyes) with uncomplicated cataracts of varying maturity degree. All patients were divided into 2 groups. Patients in the main group (30 patients, 30 eyes, 20 female and 10 male) underwent pneumotonometry before surgery and received a single instillation of Ganfort, and pneumotonometry was performed again 30 minutes after instillation (before surgery), and then again after surgery. Patients in the control group (30 patients, 30 eyes, 19 female and 11 male) underwent pnemotonometry before and after surgery. Results. The postoperative period was similar in both groups. On the first day after surgery, mean intraocular pressure in patients of the main group was 12.9 mmHg while in the control group the mean intraocular pressure was 20.1 mmHg. In patients of the main group, intraocular pressure decreased by 1/3 with Ganfort therapy on the first day after surgery, and biomicroscopic corneal findings were less pronounced in the main group compared to the control group. Conclusion. The results of our study show that even uncomplicated cataract phacoemulsification with IOL implantation leads to a reactive postoperative increase of intraocular pressure from 17.5 to 20.1 mmHg. In our study, the use of Ganfort did not cause side effects or intolerability. Ganfort use may be considered as an effective prophylactics of ocular hypertension and corneal edema after ultrasonic phacoemulsification.

Clinical efficacy of osteopathic correction in the complex treatment of patients with unoperated open-angle glaucoma

2020 ◽  
pp. 97-105
Author(s):  
E. N. Simakova ◽  
O. V. Stenkova
Keyword(s):  
Intraocular Pressure ◽  
Drug Therapy ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Randomized Study ◽  
Main Group ◽  
Control Group ◽  
Open Angle ◽  
Complex Treatment ◽  
Hypotensive Drug

Introduction. Glaucoma is one of the most significant eye diseases. It is often diagnosed, not always amenable to therapy, and can lead to a complete loss of visual functions. In recent years, the method of osteopathic correction has become widespread as one of the effective methods of treatment and rehabilitation of patients with pathologies of various body systems. In the pathogenesis of glaucoma, it is customary to distinguish a dystrophic concept, which considers primary open-angle glaucoma as a result of dystrophic changes in the connective tissue, as well as in the endothelial lining of the trabeculae and Schlemm′s canal, especially destructive changes in mitochondria and the alteration of their functional activity. A vascular concept is also distinguished. According to this concept, the central link in the pathogenesis of glaucoma is circulatory disorder in the ciliary vessels, ocular artery, and major vessels of the head and neck, it can be assumed that osteopathic correction in the treatment of patients with open-angle glaucoma will be pathogenetically substantiated and will have a positive effect on intraocular pressure and trophicity of the optic nerve. The goal of research — to study the influence of in osteopathic correction on the nature of unoperated glaucoma (stage IIA) and to substantiate the possibility of using osteopathic correction in the complex treatment of patients with this pathology.Materials and methods. A prospective controlled randomized study was conducted at 52 city polyclinics, branch 3, Moscow, from January 2018 to January 2019. 40 patients (70 eyes) aged 50 to 75 years with primary open-angle glaucoma IIA stage were examined. At this stage of the disease, patients most often seek medical care and the issue of conservative management is primarily considered. All patients were divided into two groups of 20 people: the main group and the control group. The treatment in the main group included hypotensive drug therapy and osteopathic correction. Patients of the control group received only drug therapy. All patients underwent ophthalmic (visometry, tonometry, perimetry) and osteopathic examination twice: before the treatment and after 3 months.Results. For patients with primary open-angle IIA non-operated glaucoma, regional (most often regions of the head, neck, dura mater) and local (abdominal diaphragm, iliac bones, hip and knee joints) somatic dysfunctions were the most typical. In the main group a statistically significant decrease in the frequency and severity of dysfunctions at all levels was stated. Also, in patients receiving osteopathic correction, a significant decrease in the level of intraocular pressure and perimetric indices was noted. In patients of the control group, no reliable changes in these indicators were obtained.Conclusion. The results obtained indicate that osteopathic correction is clinically effective in the complex treatment of patients with primary open-angle II A glaucoma.

The Impact of the Theory-Based Training on Beliefs of Women towards Breast Cancer Screening Behaviors

2020 ◽  
Vol 16 (3) ◽  
pp. 229-235
Author(s):  
Alireza Didarloo ◽  
Leila Mokhtary ◽  
Hamid-Reza Khalkhali ◽  
Soheila Ahangarzadeh-Rezaei
Keyword(s):  
Breast Cancer ◽  
Cancer Screening ◽  
Breast Cancer Screening ◽  
Health Beliefs ◽  
Educational Intervention ◽  
Intervention Group ◽  
Health Belief ◽  
Control Group ◽  
Belief Model ◽  
Screening Behaviors

Background: Breast cancer is the most prevalent type of cancer among women that is fatal if not diagnosed and treated in due time. Health beliefs play an important role in people's willingness to engage in health-promoting behaviors. Objective: The aim of the study was to examine the effects of the health belief model (HBM)-based training intervention on women’s health beliefs towards breast cancer screening behaviors. Methods: The study of educational intervention was conducted on women referred to healthcare centers. The sample was selected by convenient sampling and randomly assigned to control and intervention groups of 50 subjects. The intervention group received the theory-based training intervention, but the control group received only the routine care. Champion’s Health Belief Model Scale (CHBMS) was used for collecting the study data. Data analysis was performed using independent t-test, paired t-test, Chi-squared test, and correlation coefficient in SPSS software version 16.00. Results: The mean age of the subjects for control and intervention groups was 39.06±9.78, 38.32±8.27, respectively. Overall, 38%, 12% and 13%of the subjects reported breast selfexamination behavior, mammography and clinical breast examinations, respectively. Before the intervention program, the overall mean score of health beliefs in groups of control and intervention was 160.82±23.28, and 159.14±20.61, respectively. After educational intervention, the overall mean score of beliefs in the intervention group changed from 159.14±20.61 to 195.26±24.42, and it was statistically significant (p<0.001). In the control group, after the intervention, no significant changes were observed in the mean score of total health beliefs and were not statistically significant (p>0.05). Among the variables of the HBM, women's perceived self-efficacy toward breast selfexamination experienced the most positive change after an educational intervention. Conclusion: Our results indicated that HBM-based training significantly improved women’s beliefs toward breast cancer screening behaviors. It is suggested that trainers in the healthcare system use these educational approaches to promote people’s beliefs toward breast cancer and its screening methods.

scholarly journals Feasibility Study of an Educational Intervention to Improve Water Intake in Adolescent Soccer Players: A Two-Arm, Non-Randomized Controlled Cluster Trial

2021 ◽  
Vol 18 (3) ◽  
pp. 1339
Author(s):  
Rubén Martín-Payo ◽  
María del Mar Fernández-Álvarez ◽  
Edurne Zabaleta-del-Olmo ◽  
Rebeca García-García ◽  
Xana González-Méndez ◽  
...  
Keyword(s):  
Educational Intervention ◽  
Water Consumption ◽  
Intervention Group ◽  
Soccer Players ◽  
Consumption Pattern ◽  
Control Group ◽  
Personal Factors ◽  
Cluster Trial ◽  
Randomized Controlled ◽  
Ad Libitum

This study aimed to assess the feasibility of an educational intervention on hydration behavior in adolescent soccer players. A pilot study of a two-arm, non-randomized controlled cluster trial was conducted. A total of 316 players aged 13–16 agreed to participate. The response variables were the players’ participation in the intervention, their perception of the knowledge acquired, the usefulness and the overall assessment of the intervention. Hydration patterns and acquisition of knowledge on hydration behavior were also assessed. The intervention involved two elements: posters and a web app. A total of 259 adolescents completed the study (intervention group (IG) = 131; control group (CG) = 128). 80.6% of the players responded to the survey assessing the feasibility of the intervention. The mean number of correct answers regarding behavior was significantly higher in the IG (3.54; SD = 1.162) than in the CG (2.64; SD = 1.174) (p < 0.001). The water consumption pattern at all the clubs was ad libitum. Of the players, 10% did not drink any water at all during the game. In conclusion, this intervention has been shown to be feasible for implementation with adolescent soccer players. It suggests that hydration guidelines should be informed by personal factors and that ad libitum water consumption should be avoided.

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