scholarly journals Chemical Composition and Cytotoxicity Assessment of the Green Seaweed Caulerpa racemosa from Algerian West Coast

2020 ◽  
Author(s):  
Louiza Belkacemi
Keyword(s):  
Chemical Composition ◽  
West Coast ◽  
Caulerpa Racemosa ◽  
Green Seaweed ◽  
Cytotoxicity Assessment

Sulfated polysaccharides isolated from the green seaweed Caulerpa racemosa plays antinociceptive and anti-inflammatory activities in a way dependent on HO-1 pathway activation

2014 ◽  
Vol 63 (7) ◽  
pp. 569-580 ◽  
Author(s):  
Natássia Albuquerque Ribeiro ◽  
Ticiana Monteiro Abreu ◽  
Hellíada Vasconcelos Chaves ◽  
Mirna Marques Bezerra ◽  
Helena Serra Azul Monteiro ◽  
...  
Keyword(s):  
Sulfated Polysaccharides ◽  
Caulerpa Racemosa ◽  
Pathway Activation ◽  
Green Seaweed ◽  
Anti Inflammatory

scholarly journals Fighting SARS-CoV-2 with green seaweed Ulva sp. extract: extraction protocol predetermines crude ulvan extract anti-SARS-CoV-2 inhibition properties in in vitro Vero-E6 cells assay

PeerJ ◽  
2021 ◽  
Vol 9 ◽  
pp. e12398
Author(s):  
Shai Shefer ◽  
Arthur Robin ◽  
Alexander Chemodanov ◽  
Mario Lebendiker ◽  
Robert Bostwick ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Chemical Composition ◽  
Antiviral Activity ◽  
Cytopathic Effect ◽  
Average Molecular Weight ◽  
Ammonium Oxalate ◽  
Extraction Protocol ◽  
Reduction Assay ◽  
Green Seaweed

Due to the global COVID-19 pandemic, there is a need to screen for novel compounds with antiviral activity against SARS-COV-2. Here we compared chemical composition and the in vitro anti- SARS-COV-2 activity of two different Ulva sp. crude ulvan extracts: one obtained by an HCl-based and another one by ammonium oxalate-based (AOx) extraction protocols. The composition of the crude extracts was analyzed and their antiviral activity was assessed in a cytopathic effect reduction assay using Vero E6 cells. We show that the extraction protocols have a significant impact on the chemical composition, anti- SARS-COV-2 activity, and cytotoxicity of these ulvan extracts. The ulvan extract based on the AOx protocol had a higher average molecular weight, higher charge, and 11.3-fold higher antiviral activity than HCl-based extract. Our results strongly suggest that further bioassay-guided investigation into bioactivity of compounds found in Ulva sp. ulvan extracts could lead to the discovery of novel anti-SARS-CoV-2 antivirals.

scholarly journals Pengaruh Penyimpanan Beku terhadap Karakteristik Kimia dan Fisik Caulerpa racemosa, Drip, dan Filtratnya

2021 ◽  
Vol 16 (2) ◽  
pp. 131
Author(s):  
Nurhayati Nurhayati ◽  
Dina Fransiska ◽  
Agusman Agusman
Keyword(s):  
Cold Storage ◽  
Salt Content ◽  
Frozen Storage ◽  
Freezing Temperature ◽  
High Moisture ◽  
Caulerpa Racemosa ◽  
Final Sample ◽  
Test Parameters ◽  
Green Seaweed ◽  
Physical And Chemical

Caulerpa racemosa merupakan rumput laut hijau dengan kandungan air yang tinggi sehingga mudah mengalami kerusakan. Penyimpanan dalam suhu beku merupakan salah satu cara untuk memperpanjang masa simpan suatu produk. Namun, pembekuan produk juga dapat menyebabkan terjadinya berbagai perubahan yang tidak dikehendaki. Penelitian ini bertujuan untuk menganalisis pengaruh penyimpanan pada suhu beku terhadap karakteristik kimia dan fisik C. racemosa, drip, dan filtrat yang dihasilkan. Sampel berupa C. rasemosa disimpan dalam ruangan penyimpan beku (cold storage) dan diamati setiap minggunya hingga minggu ke-4. Parameter uji yang diamati meliputi rendemen, komposisi proksimat, kadar garam, uji warna (L*, a*, b*), dan viskositas, masing-masing pada C. racemosa yang ditiriskan, drip, dan filtrat C. racemosa. Hasil penelitian menunjukkan bahwa penyimpanan beku C. racemosa dapat mengurangi berat pada sampel akhir karena sebagian besar drip keluar setelah pelelehan/thawing, yaitu sekitar 77,88-84,81%. Karakteristik fisik maupun kimia C. racemosa yang disimpan selama 1 hingga 4 minggu tidak berbeda nyata antar waktu penyimpanan, namun berbeda nyata pada C. racemosa tanpa disimpan beku, yaitu pada kadar air, abu, dan garam.ABSTRACTCaulerpa racemosa is a green seaweed that has a high moisture content, so it is easily damaged. Frozen storage is one way to extend the shelf life of a product. However, freezing the product can cause various undesirable changes to occur. This study was aimed to analyze the effect of storage at freezing temperature on the chemical and physical characteristics of C. racemosa, drip, and the resulting filtrate. C. racemosa samples were stored in cold storage and observed every week until the 4th week. The test parameters observed were yield, proximate composition, salt content, color (L*, a*, b*), and viscosity on drained C. racemosa, drip, and C. racemosa filtrate. The results showed that frozen storage of C. racemosa could cause weight loss in the final sample because most of the drip came out after thawing, which was around 77.88 - 84.81%. Physical and chemical characteristics of C. racemosa stored for 1 to 4 weeks were not significantly different from unfrozen C. racemosa, i.e. water, ash, and salt content.

scholarly journals Chemical composition and immunostimulatory properties of green alga Caulerpa racemosa var peltata

2019 ◽  
Vol 30 (1) ◽  
pp. 937-954 ◽  
Author(s):  
Huili Hao ◽  
Manqin Fu ◽  
Ru Yan ◽  
Baolin He ◽  
Meiying Li ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Green Alga ◽  
Caulerpa Racemosa

scholarly journals Bioprospecting Cultivated Tropical Green Algae, Caulerpa racemosa (Forsskal) J. Agardh: A Perspective on Nutritional Properties, Antioxidative Capacity and Anti-Diabetic Potential

Foods ◽  
2020 ◽  
Vol 9 (9) ◽  
pp. 1313
Author(s):  
Abdul Qudus B Aroyehun ◽  
Shariza Abdul Razak ◽  
Kishneth Palaniveloo ◽  
Thilahgavani Nagappan ◽  
Nur Suraiza Nabila Rahmah ◽  
...  
Keyword(s):  
Ethyl Acetate ◽  
Protein Quality ◽  
Ethyl Acetate Extract ◽  
Folk Medicine ◽  
Dry Weight ◽  
Positive Control ◽  
Total Phenolic ◽  
Caulerpa Racemosa ◽  
Glucose Levels ◽  
Green Seaweed

Caulerpa racemosa (Forsskal) J. Agardh is a green seaweed used as food and folk medicine since ancient times in the Indo-Pacific region, particularly in southeast Asia. In this study, the proximate nutrient composition, phytochemical, anti-oxidant and anti-diabetic properties of sea grape C. racemosa collected from culture fishponds in Johor, Malaysia were analysed. The contents (dry weight basis) of carbohydrate, crude protein, crude lipids, ash and caloric value obtained were 33.42 ± 1.34%, 20.27 ± 0.14%, 4.20 ± 0.32%, 28.25 ± 0.27% and 2544.67 ± 7.04 cal g−1, respectively. The amino acid score (AAs) and biological protein value (213.43 mg g−1) indicated that C. racemosa presented a better protein quality. The most abundant fatty acids were C16:0 (palmitic acid: 63.27%), followed by C18:1 (oleic acid: 5.80%), and C18:2 ῳ6 (linoleic acid: 5.33%). The analysis of the ash content indicated that essential minerals and trace elements, such as Ca, Fe, and Mn, were present in the seaweed. The total phenolic content (TPC) and total flavonoid content (TFC) observed in the ethyl acetate extract were 17.88 ± 0.78 mg GAE g−1 and 59.43 ± 2.45 mg QE g−1, respectively. The ethyl acetate extract of C. racemosa demonstrated notable anti-diabetic activity in diabetic induced rats. The low (100 mg kg−1) and high (200 mg kg−1) doses of cultivated C. racemosa extract exhibited a significant decrease (p < 0.05) in blood glucose levels while preventing weight loss, reducing plasma AST, ALT levels as a sign of hepatoprotective effect and recording albumin levels similar to positive control in diabetic induced rats. The results support the usefulness of cultivated C. racemosa as a potential functional food.

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