scholarly journals Unusual location of tuberculosis: laryngeal form

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Mouna Lyoubi ◽  
Bushra Abdulhakeem ◽  
Hicham Lyoubi ◽  
Sanaa mellouk ◽  
Youssef Oukessou ◽  
...  
Keyword(s):  
Weight Loss ◽  
Direct Laryngoscopy ◽  
Histopathological Examination ◽  
Granulomatous Inflammation ◽  
Acid Fast Bacillus ◽  
Common Symptom ◽  
Multiple Biopsies ◽  
Lymph Node Tuberculosis ◽  
The Right ◽  
Laryngeal Tuberculosis

Introduction: Tuberculosis is a specific infectious disease caused by a mycobacterium: Koch's bacillus. In Morocco, the lung’s lesion is the most common site 52%, however lymph node tuberculosis is the most frequent extrapulmonary form. Laryngeal tuberculosis is rare. We present the case of a young man with a laryngeal location. Presentation of case: A 25-years-old young man, with 10-years history of alcohol and smoking consumption, was presented to our ENT department with a permanent dysphonia and dyspnea on exertion, the patient had fever and weight loss estimated to 15 kg. Clinical examination found a cachectic patient with a 38.5 ° C of temperature, without any palpable cervical mass or lymphadenopathy. A nasofibroscopy was performed showing a right vocal cord’s lesion. We performed a cervical CT scan revealing a process of the glottic and supraglottic level. Direct laryngoscopy was performed, objectifying ulcerative mass budding from the right vocal cord. Histopathological examination revealed a tuberculoid granuloma without caseating necrosis. Discussion and conclusion: Laryngeal tuberculosis is a rare and frequently under-recognized disease. It typically affects adults in the fifth decade. Literature reports dysphonia to be the most common symptom, followed by weight loss, cough, dysphagia, and odynophagia. Direct laryngoscopy allows direct visualization of the endolaryngeal lesions and performing multiple biopsies. Histopathological examination may identify granulomatous inflammation, caseating granulomas, and acid fast bacillus. However, the presence of pseudoepitheliomatous hyperplasia, which mimics squamous cell carcinoma, can make the diagnosis difficult. The pharmacologic treatment is the same as for the pulmonary forms, and results are generally excellent. Surgical intervention is reserved for those cases of airway compromise.

scholarly journals Testicular pain as an atypical presentation of sarcoidosis

2019 ◽  
Vol 101 (4) ◽  
pp. e99-e101
Author(s):  
F Chierigo ◽  
HM Alnajjar ◽  
A Haider ◽  
M Walkden ◽  
T Shaikh ◽  
...  
Keyword(s):  
Small Volume ◽  
Histopathological Examination ◽  
Granulomatous Inflammation ◽  
Middle Lobe ◽  
Atypical Presentation ◽  
Ultrasound Guided ◽  
Testicular Pain ◽  
Tract Involvement ◽  
Testicular Lesions ◽  
The Right

Sarcoidosis is a systemic granulomatous disease, with genitourinary tract involvement being very rare (0.2% of all sarcoidosis cases). Genitourinary sarcoidosis may present with a scrotal mass with or without testicular pain, often mimicking epididymo-orchitis or malignancy. Only 8 cases of genitourinary sarcoidosis have been reported in the literature in the last 14 years. We describe the case of a 25-year-old man who was referred with testicular pain. Scrotal ultrasonography demonstrated multiple bilateral hypoechoic testicular lesions that were of similar size and distributed unusually throughout the testicular parenchyma. Computed tomography detected a nodule in the middle lobe of the right lung, multiple small volume nodes in the retrocaval and left para-aortic regions, and enlarged bilateral external iliac and inguinal nodes, similar to those found in metastatic testicular cancer. Following ultrasound guided excision of one of the lesions, histopathological examination confirmed granulomatous inflammation consistent with sarcoidosis.

scholarly journals ILEOSCOPY

2015 ◽  
Vol 22 (03) ◽  
pp. 327-332
Author(s):  
Muhammad Mansoor ul Haq ◽  
Ayesha Khalil ◽  
Hafeezullah Shaikh ◽  
Shahid Mahmood ◽  
Kailash Makhijani
Keyword(s):  
Weight Loss ◽  
Terminal Ileum ◽  
Histopathological Examination ◽  
Diagnostic Yield ◽  
Granulomatous Inflammation ◽  
Normal Mucosa ◽  
Chronic Diarrhoea ◽  
Histopathological Analysis ◽  
Aged Patients ◽  
Medical College

Colonoscopy is one of the most important modalities to investigate complaintsrelated to lower gastrointestinal tract. Terminal ileum is an essential part of the completecolonoscopic examination. Objectives: To observe the diagnostic yield of ileoscopy in patientsundergoing colonoscopy. Design: Retrospective and observational study. Period: January 2010to May 2014. Setting: Liaquat National Hospital and Medical College. Patients and methods:Patients undergoing colonoscopy fulfilling inclusion and exclusion criteria were enrolled.Terminal ileum was examined and biopsies taken if abnormality present. Statistical analysiswas done by SPSS- 18. Result: A total of 1296 patients were included, 884 (68.2%) were maleand 412 (31.8%) were female. Age ranged from 15-90 years. The commonest indication wasbleeding per rectum (35.6%).1133(87.4%) patients had normal mucosa and 163 (12.6%) hadabnormal mucosa on ileoscopy. Of these 163 patients, 68 had ulcers, 56 had inflammation, 29had nodular mucosa and 10 had polyp. Histopathological examination showed non-specificinflammation in 139 patients; granulomatous inflammation in 7; reactive lymphoid hyperplasiain 8; 3 had normal result; biopsies were not taken in remaining 6 patients. By using chi-squaretest we found a significant statistical relationship between macroscopic abnormality of terminalileum mucosa and age of patients, weight loss, chronic diarrhoea, and abdominal pain. Onlogistic regression, age group, chronic diarrhoea and weight loss retained strong relationshipwith macroscopic abnormality of terminal ileum mucosa. Conclusions: Though a large numberof patients (12.6%) had abnormal terminal ileum mucosa, histopathological analysis did notshow any significant yield of ileoscopy. Terminal ileal abnormality was more common in youngand middle aged patients and in patients presenting primarily with chronic diarrhoea andweight loss.

scholarly journals A common symptom with an uncommon diagnosis

2021 ◽  
Vol 37 (1) ◽  
Author(s):  
Prabu Velayutham ◽  
Prem Davis ◽  
Nishanth Savery ◽  
Ramprasath Vaigundavasan
Keyword(s):  
Nasopharyngeal Carcinoma ◽  
Rare Disease ◽  
Histopathological Examination ◽  
Common Symptom ◽  
Computerised Tomography ◽  
Case Presentation ◽  
Contrast Enhanced ◽  
Life Threatening ◽  
The Right ◽  
Undifferentiated Nasopharyngeal Carcinoma

Abstract Background Nasopharyngeal carcinoma is one of the uncommon tumours and the most difficult tumour to diagnose at an earlier stage due to the clandestine and deceptive nature. The incidence is more common in men with a peak incidence of 50 to 60 years. The suspicion of tumour at the earliest stage is very helpful in reducing morbidity and mortality. Case presentation A 45-year-old female presented with right hemi cranial headache for 2years without any comorbidities for that she consulted many hospitals and got symptomatic and empherical treatment in which her symptoms resolved temporarily and recurred. We did diagnostic nasal endoscopy and found a smooth globular mass in the right nasopharynx with contrast enhanced computerised tomography mass extending into the muscle plane which was found with the confirmation of diagnosis as undifferentiated nasopharyngeal carcinoma by histopathological examination and treated accordingly. Conclusion Although the diagnosis of the nasopharyngeal carcinoma in the earlier stage is difficult, it is an imperative one because the prognosis depends upon the stage of the disease in which it has been diagnosed. The clinicians always should have a suspicion of the rare disease for a day-to-day unresolved symptom, because the earlier diagnosis and appropriate management helps in the prevention of the life-threatening complications of any disease.

scholarly journals Fish Tank Granuloma – a Case Report

2017 ◽  
Vol 9 (4) ◽  
pp. 154-158
Author(s):  
Tijana Boljević ◽  
Željko Mijušković ◽  
Lidija Kandolf Sekulović ◽  
Biserka Vukomanović-Đurđević
Keyword(s):  
Histopathological Examination ◽  
Salt Water ◽  
Parasitic Infection ◽  
Granulomatous Inflammation ◽  
Atypical Mycobacterium ◽  
Dorsal Aspect ◽  
History Of ◽  
Fish Tank ◽  
The Right ◽  
Fish Tank Granuloma

Abstract Swimming-pool granuloma and fish tank granuloma refer to the infections caused by Mycobacterium marinum. After having been discovered in salt water fish in Philadelphia Aquarium and described in 1926, this skin infection was first reported in humans in 1951. It developed in people who had swum in contaminated swimming pools. M. marinum is a non-tuberculous, atypical mycobacterium, which is found on plants, soil and fish in freshwater and salt water worldwide. Humans become infected usually after trauma and contact with an aquatic environment. Infection is limited to the skin and usually occurs in healthy individuals, but in immunocompromised patients the infection may disseminate or spread to the subcutis and bone. The lesions usually appear as solitary nodules or plaques that may lead to suppurative ulcers after 2-3 weeks of incubation. Occasionally, there may be sporotrichoid spread along lymphatics. Its diagnosis is frequently delayed, probably because the infection is very rare and a history of aquatic exposure, which is present in the majority of cases, is often overlooked. Common misdiagnoses include fungal and parasitic infection, cellulitis, verrucous tuberculosis of the skin, gout, rheumatoid arthritis, a foreign body and a skin tumour. We present a case of a 39-year-old Caucasian male with a 12-month history of a single erythematous tender nodule on the right dorsal aspect of the right hand. Histopathological examination revealed longstanding suppurated granulomatous inflammation. The infection was not responsive to several courses of antibiotics until we introduced doxycycline capsules as monotherapy which led to complete remission after 5 months.

scholarly journals Tuberculosis of the Larynx: A Review of Two Cases

2017 ◽  
Vol 7 (1) ◽  
pp. 27-30
Author(s):  
Kamalika P Roy ◽  
Dhruba J Datta ◽  
Srikanth Madam ◽  
Praneeth K Koduru
Keyword(s):  
Weight Loss ◽  
Histopathological Examination ◽  
Early Recognition ◽  
Case Reports ◽  
Vocal Cords ◽  
Desirable Outcome ◽  
History Of ◽  
Microlaryngeal Surgery ◽  
Subepithelial Layer ◽  
Laryngeal Tuberculosis

ABSTRACT Aim To investigate the changes in the vibratory function of the vocal cords in two diagnosed cases of tuberculosis during and after completion of treatment. Background Laryngeal tuberculosis is one of the most common granulomatous diseases of the larynx. Patients present with hoarseness, irritation in throat, dysphagia, and breathlessness. The hoarseness occurs due to the granulomatous reaction involving the subepithelial layer of the vocal cords, which heal with fibrosis. Case reports A 56-year-old male presented with a 2-month history of cough, hoarseness allegedly precipitated by vocal abuse, dysphagia, weight loss, and evening rise of temperature. There was associated history of tobacco and betel nut intake. A 50-year-old female patient presented with complaints of hoarseness of 3 months duration not associated with any cough, dysphagia, fever, weight loss, or breathlessness. Clinical examination showed whitish lesions in the vocal cords. Microlaryngeal surgery done in both cases for collecting biopsy specimen showed a chronic inflammatory process with granuloma. Antitubercular treatment consisting of Isoniazid, Rifampicin, Pyrazinamide, and Ethambutol was given for a period of 6 months. The patients were assessed at the end of 2 and 6 months of treatment symptomatically and clinically with fiber-optic laryngoscopy and stroboscopy. Significant improvement in the vibratory pattern of vocal cords and voice quality was noted in both the patients. Conclusion Early recognition of the disease and initiation of treatment are necessary for a desirable outcome of vibratory function of the vocal cords. Clinical significance As patients present with nonspecific symptoms, an accurate diagnosis of laryngeal tuberculosis can be made by a proper histopathological examination and acid-fast staining of specimen obtained by microlaryngeal surgery. Early initiation of treatment is the key to better outcome. How to cite this article Roy KP, Datta DJ, Madam S, Koduru PK. Tuberculosis of the Larynx: A Review of Two Cases. Int J Phonosurg Laryngol 2017;7(1):27-30.

Primary Cutaneous Granulomatous Phlebitis of the External Jugular Vein

2002 ◽  
Vol 16 (3) ◽  
pp. 125-127
Author(s):  
S. Shetty ◽  
S. Gupta ◽  
P. Makhija ◽  
S. Hasan
Keyword(s):  
Jugular Vein ◽  
Inflammatory Diseases ◽  
Histopathological Examination ◽  
Granulomatous Inflammation ◽  
Neck Surgery ◽  
Neck Mass ◽  
External Jugular Vein ◽  
College Hospital ◽  
Medical College ◽  
The Right

Design: Case report. Setting: Department of Otolaryngology and Head and Neck Surgery, St. John's Medical College Hospital, India. Patient: A 22-year-old man with a cord-like neck mass of 6 months' duration. Investigations and intervention: Investigations included Doppler ultrasound of the neck, which showed thrombosis of the right external jugular vein. Wedge biopsy revealed a granulomatous inflammation with focal necrosis completely replacing the vessel. Serological testing for vasculitides was negative. Transcervical excision of the vein was carried out after identifying normal vessel distally and proximally. Histopathological examination of the vein proved the lesion consistent with primary cutaneous granulomatous phlebitis (PCGP). Conclusion: Isolated venous inflammatory diseases with neither identifiable active vasculitis nor arteritis are rarely seen. PCGP is distinctly unusual. We report a case of PCGP of the external jugular vein presenting as an elongated cord-like nodular lesion in the lateral neck of insidious onset.

scholarly journals The Detection of Proximal Colon Polyps and Its Importance in Screening Colonoscopy

2017 ◽  
Vol 2 (3) ◽  
pp. 219-223
Author(s):  
Răzvan Opaschi ◽  
Simona Bățagă ◽  
Ioan Macarie ◽  
Imola Török ◽  
Anca Negovan ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Sigmoid Colon ◽  
Histopathological Examination ◽  
Proximal Colon ◽  
Screening Colonoscopy ◽  
Colon Polyps ◽  
Tubular Adenoma ◽  
Right Colon ◽  
Multiple Biopsies ◽  
The Right

Abstract Background: Colon polyps are precursors of colorectal cancer (CRC), therefore their endoscopic detection is very important. A shift of in the localization of colorectal polyps toward the proximal colon has been recently observed in Western countries. Aim: The aim of this paper was to establish the most important clinical and endoscopic aspects of right colon polyps and to correlate them with their histopathological types, with an emphasis on sessile serrated adenomas/polyps (SSA/Ps). Material and method: We perfomed a retrospective study on a series of consecutive patients who underwent colonoscopy in the Gastroenterology and Endoscopy Unit of the County Emergency Clinical Hospital of Tîrgu Mureș between January 1, 2010 – December 31, 2014, comparing the results with those of patients who underwent colonoscopy between January 1, 2005 – December 31, 2009. In all cases with abnormal aspects at endoscopy, multiple biopsies were taken for histopathological examination. Only cases where the diagnosis of colon polyp was confirmed by the Histopathology Department were included in the study. Results: In the 2010–2014 period there were 871 patients diagnosed with colon polyps (1,038 polyps), with a mean age of 62.28 years. The most frequent histopathological form was tubular adenoma in 55.97% of cases (n = 581). SSA/Ps were found in 66 patients (75 polyps). Considering all polyps, the most frequent localization was in the sigmoid colon in 32.36% of cases (n = 336), but for SSA/Ps the most common localization was the ascending colon in 24% of cases (n = 18), followed by the sigmoid colon in 21.33% of cases (n = 16). Compared with patients investigated between 2005 and 2009, we found an increasing localization in the right colon, from 10.43% (n = 67) in 2005–2009 to 15.41% (n = 160) in 2010–2014. SSA/Ps were found in the right colon in 5.97% of cases (n = 4) in the first period compared with 11.25% of cases (n = 18) in the second period. Conclusions: In the last years we found an increasing localization of colon polyps in the right colon. These findings underscore the importance of high quality colonoscopy to maximize protection against colorectal cancer.

Popliteal artery thrombosis secondary to a tibial osteochondroma

VASA ◽  
2011 ◽  
Vol 40 (3) ◽  
pp. 251-255 ◽  
Author(s):  
Gruber-Szydlo ◽  
Poreba ◽  
Belowska-Bien ◽  
Derkacz ◽  
Badowski ◽  
...  
Keyword(s):  
Case Report ◽  
Magnetic Resonance Angiography ◽  
Popliteal Artery ◽  
Doppler Ultrasonography ◽  
Histopathological Examination ◽  
Previous History ◽  
Plain Radiography ◽  
Artery Thrombosis ◽  
History Of ◽  
The Right

Popliteal artery thrombosis may present as a complication of an osteochondroma located in the vicinity of the knee joint. This is a case report of a 26-year-old man with symptoms of the right lower extremity ischaemia without a previous history of vascular disease or trauma. Plain radiography, magnetic resonance angiography and Doppler ultrasonography documented the presence of an osteochondrous structure of the proximal tibial metaphysis, which displaced and compressed the popliteal artery, causing its occlusion due to intraluminal thrombosis..The patient was operated and histopathological examination confirmed the diagnosis of osteochondroma.

Evaluation of Breast Lumps by Ultrasound and Correlation with Histological Findings

2020 ◽  
Vol 23 (1) ◽  
pp. 10-12
Author(s):  
Nelema Jahan ◽  
Md. Mamunur Rahman ◽  
Mohammad Shahidul Alam ◽  
Md Saiful Islam
Keyword(s):  
Histopathological Examination ◽  
Breast Diseases ◽  
Histopathological Study ◽  
Common Symptom ◽  
Breast Lump ◽  
Histopathological Findings ◽  
Malignant Breast ◽  
Breast Lumps ◽  
One Year ◽  
A Prospective Study

Background: A breast lump is the most common symptom associated with both benign and malignant breast diseases. Therefore, a distinction of benign from malignant lump is of importance for proper management. Though a definitive diagnosis is possible with imaging for all the lesions, histopathological study is proven essential for confirming the diagnosis. Objective: The objective of this study was to evaluate the role of USG and histopathological findings of different breast lump in diagnosis and their comparison. Methods: A prospective study was conducted over a period of one year from January 2017 to December 2017. A total of 116 patients were included in this study. All breast lumps underwent surgery and the ultrasound findings of these lumps were compared with the histopathological findings. Data were collected from these patients by a preformed questionnaire and finally the data were analyzed. Results: Out of 116 patients only 21 cases were reported as malignant in ultrasound report but histopathology revealed 31 malignant patients. On histopathological examination 10 benign cases turned out to be malignant. Conclusion: The present study was undertaken to evaluate in diagnosing breast mass lesions individually by ultrasound and compared with histopathology for definitive management of a patient. Journal of Surgical Sciences (2019) Vol. 23 (1) : 10-12

Successful Control of a Co-Infection Caused by Candida albicans and Pseudomonas aeruginosa in Keratitis

2020 ◽  
Vol 20 ◽  
Author(s):  
Debarati Paul ◽  
Suman Saha ◽  
Neelam Singh ◽  
Jayansgu Sengupta ◽  
Santi M. Mandal
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Candida Albicans ◽  
Histopathological Examination ◽  
Specific Interaction ◽  
Major Threat ◽  
Effective Combination ◽  
Male Farmer ◽  
Successful Control ◽  
The Right ◽  
Corneal Button

Introduction: Nowadays, co-infection by interspecific organisms is major threat in infection control. To identify the effective combination of drugs to control the keratitis caused by Candida albicans with Pseudomonas aeruginosa are attributed in this study. Materilas and Methods: The patient of a 47 years old male farmer with infection in the right eye which showed redness and watering was treated with fortified cefazolin and fortified tobramycin before referral. No pigmentation or vascularisation was noted. The excised corneal button was also subjected to microbiological and histopathological examination. Results: A rare case of keratitis caused by co-infection of Candida albicans with Pseudomonas aeruginosa was identified. Results confirmed the inter-specific interaction of the two microorganisms. Conclusion: Cases of co-infection by Candida and Pseudomonas are not abundantly reported and difficult to treat. In this case, treatment involved Amphotercin-B and ciprofloxacin, effectively eradicated the infection. This therapy may be successfully implied for such cases of co-infection in future.

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