Evaluation of Breast Lumps by Ultrasound and Correlation with Histological Findings

2020 ◽  
Vol 23 (1) ◽  
pp. 10-12
Author(s):  
Nelema Jahan ◽  
Md. Mamunur Rahman ◽  
Mohammad Shahidul Alam ◽  
Md Saiful Islam
Keyword(s):  
Histopathological Examination ◽  
Breast Diseases ◽  
Histopathological Study ◽  
Common Symptom ◽  
Breast Lump ◽  
Histopathological Findings ◽  
Malignant Breast ◽  
Breast Lumps ◽  
One Year ◽  
A Prospective Study

Background: A breast lump is the most common symptom associated with both benign and malignant breast diseases. Therefore, a distinction of benign from malignant lump is of importance for proper management. Though a definitive diagnosis is possible with imaging for all the lesions, histopathological study is proven essential for confirming the diagnosis. Objective: The objective of this study was to evaluate the role of USG and histopathological findings of different breast lump in diagnosis and their comparison. Methods: A prospective study was conducted over a period of one year from January 2017 to December 2017. A total of 116 patients were included in this study. All breast lumps underwent surgery and the ultrasound findings of these lumps were compared with the histopathological findings. Data were collected from these patients by a preformed questionnaire and finally the data were analyzed. Results: Out of 116 patients only 21 cases were reported as malignant in ultrasound report but histopathology revealed 31 malignant patients. On histopathological examination 10 benign cases turned out to be malignant. Conclusion: The present study was undertaken to evaluate in diagnosing breast mass lesions individually by ultrasound and compared with histopathology for definitive management of a patient. Journal of Surgical Sciences (2019) Vol. 23 (1) : 10-12

scholarly journals Histopathological study of benign breast lesions

2021 ◽  
Vol 6 (4) ◽  
pp. 295-300
Author(s):  
M Janaki ◽  
R Poojasree ◽  
M Anil Kumar ◽  
A Hareesh Kumar ◽  
T Nagachandana
Keyword(s):  
Histopathological Examination ◽  
Nipple Discharge ◽  
Breast Diseases ◽  
Histopathological Study ◽  
Breast Lesions ◽  
Young Females ◽  
Benign Breast Diseases ◽  
Different Types ◽  
Benign Breast Lesions ◽  
Breast Lumps

Benign breast lesions are common in young females and are painless. Fibroadenoma is the commonest lesion among all the breast lesions and occurs in any age.1:To study the age and sex wise distribution of benign breast lesions; 2: To study the clinicopathological changes of benign breast diseases; 3: To study different types of benign breast lesions; 4. To study the histomorphological changes of benign breast lesions with clinical correlation.A prospective study of two years was done to evaluate the different types, patterns of benign breast lesions in females in relation to age, clinical and radiological features.A total of 140 benign breast diseases were studied. Fibroadenoma (76; 54.2%) was the most common lesion noted in younger females (18-24yrs) followed by fibrocystic disease (25; 17.8%) & benign phyllodes (14; 10%).FNAC followed by histopathological examination were the diagnostic criteria used for confirmation of the lesions.Benign breast lesions were common in young females, presented with painless, mobile breast lumps. Mastalgia and nipple discharge were other symptoms.

scholarly journals Assessment of clinical significance of serum uric acid, serum bilirubin and serum creatinine in patients with breast lump

2021 ◽  
Vol 8 (11) ◽  
pp. 3312
Author(s):  
Shoranki Pardhan ◽  
Anuradha Chaudhary ◽  
Rahul Shivhare ◽  
Sonveer Gautam
Keyword(s):  
Uric Acid ◽  
Serum Creatinine ◽  
Serum Uric Acid ◽  
Serum Bilirubin ◽  
Histopathological Examination ◽  
Initial Assessment ◽  
Normal Range ◽  
Breast Lump ◽  
Malignant Breast ◽  
Breast Lumps

Background: Breast cancer is the most common cancer in females, approximately a quarter of all cancers. Several tumor markers are being studied now a days like α feto protein, carcinoembryonic antigen, and human chorionic gonadotropin but, the cost of these analytical methods is very high. This study is directed to assess prognostic value of serum uric acid, serum bilirubin and serum creatinine in breast lump cases. And to compare variation in benign and malignant breast lumps in relation to serum uric acid, serum bilirubin and serum creatinine values.Methods: Observational and prospective study conducted in Hamidia Hospital, Bhopal from November 2018-July 2020 included 100 patients. 50 patients were having benign breast lumps and other 50 patients malignant. Categorization of the patients done on the basis of histopathological examination. Autoanalyzer was used for estimation of serum uric acid, serum bilirubin and serum creatinine.Results: High serum uric acid level may anticipate poor prognosis in carcinoma breast, and it may perform a promising role in the management of the same. The level of serum bilirubin was slightly more or within normal range. The level of serum creatinine was within normal range in absence of any renal impairment by other etiology.Conclusions: The evaluation of serum uric acid and serum bilirubin may be useful for predicting prognosis in females with malignant breast lump and can provide help in making diagnosis during the initial assessment of the patient presenting with breast lump.

scholarly journals Study of clinical, imaging and pathological assessment of breast lumps: an observational study

2020 ◽  
Vol 7 (5) ◽  
pp. 1452
Author(s):  
Sumedha Laul ◽  
Divish Saxena ◽  
Nitin Wasnik
Keyword(s):  
Final Diagnosis ◽  
Needle Aspiration ◽  
Age Group ◽  
Breast Lump ◽  
Aspiration Cytology ◽  
Malignant Breast ◽  
Palpable Breast ◽  
Needle Aspiration Cytology ◽  
Breast Lumps

Background: A palpable lump in a woman’s breast could be benign or malignant and it requires prompt evaluation to confirm or exclude cancer. This study aims to establish the correlation between clinical and radiological parameters for provisional diagnosis of breast lumps and the role of histopathology for final diagnosis of these breast lumps.Methods: Total 275 female patients with palpable breast lumps were included in the study, where a detailed history was recorded and clinical examination was done. All patients underwent ultrasonography of the breast along with fine needle aspiration cytology or histopathology, wherever indicated.Results: Benign breast lumps were found more commonly in 18-30 years of age group whereas malignant breast lumps were seen more commonly in the 41-60 years age group and the incidence increased with age. Fixity to skin was present in 5.1% and fixity to chest wall was present in 5.8% respectively, and all of these cases turned out to be malignant.Conclusions: Attributing factors for suspicion of malignant lumps are advanced age, fixity to surrounding structures, presence of ulceration and peau’d orange breast skin appearance. Although for confirmation of malignancy from a suspected breast lump requires either cytology or histopathology of the excised specimen.

scholarly journals Clinicopathological study of leiomyomas in hysterectomy specimens

2018 ◽  
Vol 7 (4) ◽  
pp. 1509 ◽  
Author(s):  
Manpreet Kaur ◽  
Rajiv Kamal Gupta ◽  
Simrat Jit Kaur ◽  
Panchampreet Kaur
Keyword(s):  
Histopathological Examination ◽  
Reproductive Age ◽  
Benign Tumors ◽  
Histopathological Study ◽  
Histopathological Diagnosis ◽  
Age Group ◽  
Diagnosis And Prognosis ◽  
Common Complaint ◽  
A Prospective Study ◽  
Reproductive Age Group

Background: Leiomyomas are benign tumors of smooth muscle cells commonly encountered in women of reproductive age group. Aim of this study was to conduct a histopathological study of leiomyomas in hysterectomy specimens and to correlate them with clinical findings.Methods: A prospective study was done on 130 hysterectomy specimens clinically diagnosed as leiomyoma. The specimens were subjected to histopathological examination.Results: In this study, the most common age group was 31-50 years (87.69%). Most common complaint was menorrhagia (51.54%). In endometrium, the most common histopathological diagnosis was proliferative phase (46.15%) followed by endometrial hyperplasia (19.23%). The most common secondary change was hyalinization and the most common site was intramural (62.9%).Conclusions: Hysterectomy is a commonly performed procedure in the management of uterine leiomyomas. The ultimate diagnosis and prognosis depends on the histopathological examination; therefore, every operated specimen must be subjected to histopathology. 

scholarly journals Frequency of benign breast diseases in female patients presenting with breast lumps - a study at Sir Ganga Ram Hospital, Lahore

2016 ◽  
Vol 11 (4) ◽  
Author(s):  
Kamran Ali ◽  
Muhammad Hassan Abbas ◽  
Sadia Aslam ◽  
Muhammad Aslam ◽  
Khalid Javed Abid ◽  
...  
Keyword(s):  
Breast Imaging ◽  
Final Diagnosis ◽  
Breast Diseases ◽  
Fibrocystic Disease ◽  
Female Patients ◽  
Benign Breast Diseases ◽  
Fibrocystic Change ◽  
Breast Lumps ◽  
One Year ◽  
Age Range

Objective: To determine the frequency of benign breast diseases in female patients in our setup. Design: Prospective descriptive study. Place and duration of study: The study was carried on female patients presenting at surgical out door of Sir Ganga Ram Hospital, Lahore during one year i.e. January 2001 to January 2002. Patients and methods: Two hundred female patients presenting with breast lumps at surgical out door of Sir Ganga Ram Hospital, Lahore during one year were studied. All the patients were examined clinically with special emphasis on breast, axilla and supra clavicular fossae. Basic laboratory investigations including blood complete examination, urine complete examination and chest X -ray were done for all the patients. Breast imaging and FNAC of lumps were also done. Final diagnosis was based upon histological examination of the tissues biopsied from the lump. After collecting data, written in proforma, window SPSS software was used to analyze the results. Results: This study shows a high f requency of fibroadenoma (45%) in Pakistani females. Fibrocystic disease is second in frequency and accounts for 36% patients.8% patients had intraductal papilloma and three percent suffered from duct ectasia.5% patients had other conditions related to breast including two patients presenting with pre histological diagnosis of fibrocystic disease who turned out to be malignant after histopathology. Most of the patients had age range of 20-29 years. Conclusion: Fibroadenoma is the commonest of all benign breast diseases in Pakistani women. Fibrocystic change is the second in this regard. Benign lesions of the breast can resemble its carcinoma on clinical examination.

scholarly journals A prospective study of cases of urolithiasis with reference to risk factors, surgery and outcomes

2018 ◽  
Vol 5 (12) ◽  
pp. 3826
Author(s):  
Ramalinga Reddy Rachamalla ◽  
Rajasekhar Konduru
Keyword(s):  
Demographic Data ◽  
Renal Calculi ◽  
Good Alternative ◽  
Urinary Stone ◽  
Stone Disease ◽  
P Value ◽  
Common Symptom ◽  
Ethical Committee Approval ◽  
One Year ◽  
A Prospective Study

Background: Urinary stone disease or Urolithiasis is on a surge of increase with an incidence of 6.3% among men and 4.1% among women. The site of development of the calculi is variable and dependable on various factors. The aim of study was to identify the various predisposing and causative factors, with clinical presentations and complications and to identify identifying various modalities of treatment.Methods: A prospective observational study was conducted for a period of one year after ethical committee approval. All the cases of Urolithiasis confirmed by ultra-sonogram was included and socio demographic data, clinical and laboratory investigations were performed on all the cases and the data was entered in Microsoft excel and analyzed. Surgical approach to all the cases were recorded.Results: 150 cases with 64% males and 36% females were included in the study and mean age was 38.21 years. Pain abdomen was the most common symptom. Calculus was most common on right side with upper pole of the kidney being most common site of calculus in the study. Mean size of calculus in the study was 12.5mm. Statistically significant association was found with Diabetes mellitus, Obesity and low water intake (P value <0.05) in the study. Ureteroscopy (URS) was performed in 36 cases (24%), PCNL in 22 cases (14.67%), ECSWL in 46 (30.67%), cystolithotomy in 34 (22.67%) and urethral extraction in 12 cases (8%).Conclusions: For renal calculi, PCNL is the best treatment modality as of now, but it is associated with greater post-operative morbidity. For stone less than 1cm size, ECSWL is a good alternative to PCNL, but has poor clearance rate and thus greater need for auxiliary procedure. For ureteral calculi, both ECSWL and ureteroscopy have given good results but ECSWL is better tolerated by the patients.

scholarly journals Spectrum of breast diseases in a rural himalayan region of Western Nepal: a hospital based study

2020 ◽  
Vol 10 (3) ◽  
pp. 95-97
Author(s):  
Harihar Devkota ◽  
Suryaman Menyangbo ◽  
Kapil Amgain
Keyword(s):  
Health Sciences ◽  
Breast Diseases ◽  
Age Group ◽  
Breast Abscess ◽  
Fibrocystic Disease ◽  
Benign Diseases ◽  
The Third ◽  
Malignant Breast ◽  
One Year ◽  
Benign Disorders

Background: Breast diseases, among the most common diseases in females occur in various pat­terns from benign to malignant. Their identification is crucial as some of the benign disorders pose threat to turn into malignancy. This study was aimed to determine the spectrum of breast diseases. Methods: This was a hospital based retrospective study among all the patients in General Surgery OPD of Karnali Academy of Health Sciences, Teaching Hospital, diagnosed with breast diseases during one year period from August 2019 to July 2020 AD. Data were extracted and entered in SPSS version 16 for further analysis. Results: Out of 110 cases, only 4 (3.96%) were male. Almost half 54 (49.09%) of the cases were in the age group of 21-30 years. Fibrocystic disease, Breast Abscess and fibroadenoma, and cracked nipple were 39 (35.45%), 38 (34.54%, 15 (13.63%) and 8 (7.28%) respectively. The benign diseases were seen mostly in the younger population while malignant breast diseases were seen in the older population. Mastalgia was mostly seen in the twenties (17.3%) and the thirties (10%) while Breast abscess was commonly encountered in the twenties (16.4%) and the teens (11.8%). The gynaecomastia were seen only in four males. Conclusions: Fibrocystic breast diseases, Mastitis with or without abscess, fibroadenoma and cracked nipples were the first four most common breast diseases in females. The younger popula­tion had predilection towards the benign diseases which occurred most frequently in the third decade while the malignant occurred in sixth and seventh decade.

Evaluation and comparison of type I tympanoplasty efficacy and histopathological changes to the tympanic membrane in dry and wet ear: a prospective study

2015 ◽  
Vol 129 (10) ◽  
pp. 945-949 ◽  
Author(s):  
R Shankar ◽  
R S Virk ◽  
K Gupta ◽  
A K Gupta ◽  
A Bal ◽  
...  
Keyword(s):  
Prospective Study ◽  
Success Rate ◽  
Tympanic Membrane ◽  
Histopathological Examination ◽  
Chronic Otitis Media ◽  
Type I ◽  
Significant Difference ◽  
Type I Tympanoplasty ◽  
One Year ◽  
A Prospective Study

AbstractObjective:This study aimed to compare the success rate of type I tympanoplasty in active (wet) and inactive (dry) mucosal chronic otitis media.Methods:A prospective study was performed of 35 patients each with dry ear and wet ear undergoing type I tympanoplasty in the Otolaryngology Department, Postgraduate Institute of Medical Education and Research, India. All patients underwent type I tympanoplasty between January 2010 and June 2011 by the post-auricular approach. Samples of the remnant tympanic membrane were sent for histopathological examination.Results:After a minimum follow up of one year, the success rate was 88.6 per cent for dry ears and 80 per cent for wet ears. Neither the type (p = 0.526) nor the presence (p = 0.324) of discharge influenced the success rate. Histopathological examination of the tympanic membrane margins was performed for 46 patients: of these, 19 showed evidence of vascularity and 27 did not. There was no significant difference in success rate between groups (p = 0.115).Conclusion:The success rate was not influenced by the presence of ear discharge at the time of surgery, and tympanic membrane vascularity did not influence graft uptake.

scholarly journals Neuronal hyperplasia in clinically diagnosed acute appendicitis: A histopathological study in tertiary care centre

2021 ◽  
Vol 11 (1) ◽  
pp. 1864-1867
Author(s):  
Riddhi A Parmar ◽  
Riti P Dixit ◽  
Keval Arvindbhai Patel ◽  
Bhawana S Sharma ◽  
Jigna Dave
Keyword(s):  
Acute Appendicitis ◽  
Inflammatory Responses ◽  
Histopathological Examination ◽  
Tertiary Care ◽  
Histopathological Study ◽  
Tertiary Care Centre ◽  
S 100 ◽  
One Year ◽  
Haematoxylin And Eosin Stain ◽  
Neuronal Hyperplasia

Background: Acute appendicitis is one of the most common general surgical emergencies. Around 20-25% of patients who have an appendectomy done are found not to have acute appendicitis on histopathological examination. There is increasing evidence of the involvement of the enteric nervous system, in the immune regulation and monitoring the inflammatory responses. The present study was done to elucidate if neuronal changes in the appendix could be the cause of clinical acute.Materials and methods: Hospital records of 60 cases who were diagnosed as acute appendicitis clinically and who underwent appendectomy either laparoscopic or open, were reviewed. Histopathological records of these resected appendices submitted to the department of histopathology, GAIMS, G.K. General Hospital Bhuj were reviewed for one year for the presence or absence of acute appendicitis or neuronal hyperplasia. Routine Haematoxylin and Eosin stain and S-100 protein staining was done on all these 60 cases.Results: Out of these 60 specimens of appendices received, histopathological examination revealed neuronal hyperplasia in the submucosa and muscularis layer on all the 60 cases. Grading of neuronal hyperplasia was done in all the cases. Out of these 60 specimens of appendices, histopathological examination revealed 48 cases of histopathologically positive acute appendicitis and 12 cases of histopathologically negative acute appendicitis.Conclusions: Neuronal hyperplasia has an important role in the pathogenesis of appendiceal colic in patients with both histopathologically positive acute appendicitis and histopathologically negative acute appendicitis

scholarly journals ANTERIOR TRIANGLE NECK SWELLINGS- RELATIVE INCIDENCE OF VARIOUS CLINICAL CAUSES

2020 ◽  
pp. 1-2
Author(s):  
Saima Tabassum ◽  
Chandpreet Kour ◽  
Sajid Iqbal
Keyword(s):  
Histopathological Examination ◽  
Clinical History ◽  
Needle Aspiration ◽  
Lateral Neck ◽  
Neck Swelling ◽  
Duct Cyst ◽  
Submandibular Region ◽  
Magnetic Resonance Imaging Mri ◽  
One Year ◽  
A Prospective Study

Aims and objectives- The intented aim of our study was to find out the cause of various benign anterior triangle neck swellings. Material And Methods- A prospective study was carried out at ENT department of MMIMSR for a period one year from June 2017 to May 2018. The sample size consist of 50 patients. All patients attending the ENT OPD with neck swelling were included in this study. These patients were evaluated based on clinical history and examinations. Pathological investigations like FNAC (Fine needle aspiration cytology) & histopathological examination (HPE) along with radiological examination such as Ultrasounography (USG), X-ray, Magnetic resonance imaging (MRI), Computed tonnography (CT Scan) was carried out wherever it was required. Result – Out of 50 patients, 46 percent were male patients (n=23) and 54 percent were female patients (n=27). Patients with the age from 5 years to 70 years were affected with the mean age of 42years. Midline neck neck swellings were more common than lateral neck swellings (Anterior triangle). Among the midline neck swelling ,thyroid gland pathology was commonest with 72.4% of cases (n=21), followed by Thyroglossal duct cyst with 24% cases(n=7). Thyroglossal cyst was the most common congenital swelling seen in our study. In the lateral neck, salivary gland pathology was the commonest cause of neck swelling with 52.3% cases (n=11) followed by branchial cyst with 23.8% cases (n=5). 14.3% of cases (n=3) with tubercular lymphadenopathy were found in submandibular region

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