ILEOSCOPY

Colonoscopy is one of the most important modalities to investigate complaintsrelated to lower gastrointestinal tract. Terminal ileum is an essential part of the completecolonoscopic examination. Objectives: To observe the diagnostic yield of ileoscopy in patientsundergoing colonoscopy. Design: Retrospective and observational study. Period: January 2010to May 2014. Setting: Liaquat National Hospital and Medical College. Patients and methods:Patients undergoing colonoscopy fulfilling inclusion and exclusion criteria were enrolled.Terminal ileum was examined and biopsies taken if abnormality present. Statistical analysiswas done by SPSS- 18. Result: A total of 1296 patients were included, 884 (68.2%) were maleand 412 (31.8%) were female. Age ranged from 15-90 years. The commonest indication wasbleeding per rectum (35.6%).1133(87.4%) patients had normal mucosa and 163 (12.6%) hadabnormal mucosa on ileoscopy. Of these 163 patients, 68 had ulcers, 56 had inflammation, 29had nodular mucosa and 10 had polyp. Histopathological examination showed non-specificinflammation in 139 patients; granulomatous inflammation in 7; reactive lymphoid hyperplasiain 8; 3 had normal result; biopsies were not taken in remaining 6 patients. By using chi-squaretest we found a significant statistical relationship between macroscopic abnormality of terminalileum mucosa and age of patients, weight loss, chronic diarrhoea, and abdominal pain. Onlogistic regression, age group, chronic diarrhoea and weight loss retained strong relationshipwith macroscopic abnormality of terminal ileum mucosa. Conclusions: Though a large numberof patients (12.6%) had abnormal terminal ileum mucosa, histopathological analysis did notshow any significant yield of ileoscopy. Terminal ileal abnormality was more common in youngand middle aged patients and in patients presenting primarily with chronic diarrhoea andweight loss.

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Routine Histopathological Analysis of Pediatric and Adult Tonsils

Otorhinolaryngology Clinics - An International Journal ◽

10.5005/jp-journals-10003-1216 ◽

2016 ◽

Vol 8 (1) ◽

pp. 11-12

Author(s):

K Shoba ◽

B Harikumar ◽

P Jayaganesh ◽

K Srinivasan

Keyword(s):

Risk Factors ◽

Histological Examination ◽

Epidermoid Cyst ◽

Histopathological Examination ◽

Lymphoid Hyperplasia ◽

Reactive Lymphoid Hyperplasia ◽

Histopathological Analysis ◽

Adult Group ◽

Medical College ◽

Adult Tonsillectomy

ABSTRACT Introduction Making a protocol is a must to overcome the controversy of doing routine histopathological examination of tonsillectomy specimen. Materials and methods Histopathological report of 100 consecutive tonsillectomy specimens that reached the pathology department of Saveetha Medical College was analyzed. Results Histological examination of the 154 pediatric tonsils showed reactive lymphoid hyperplasia in all the patients. One specimen had a small cartilaginous choristoma. In the 46 adult tonsils, there were two lymphoma, one extensive osteocartilaginous choristoma, and one epidermoid cyst of tonsil. Discussion As the histopathological examination in the pediatric group did not reveal any finding, it can be done only in patients with risk factors. The adult group showed two cases of Hodgkins lymphoma, one epidermoid cyst of tonsil and one osteocartilaginous choristoma tonsil. Hence, we suggest to continue the practice of routine histopathological analysis in adults. Conclusion We suggest continuing the practice of routine histopathological examination of all adult tonsillectomy specimens. How to cite this article Shoba K, Harikumar B, Jayaganesh P, Srinivasan K. Routine Histopathological Analysis of Pediatric and Adult Tonsils. Int J Otorhinolaryngol Clin 2016;8(1):11-12.

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Pleural biopsy in the diagnosis of lymphocytic exudative pleural effusion

Annals of King Edward Medical University ◽

10.21649/akemu.v11i4.1116 ◽

2016 ◽

Vol 11 (4) ◽

Author(s):

Javed Asghar Magsi ◽

Saulat Ullah Khan ◽

Shamshad Rasul Awan

Keyword(s):

Pleural Effusion ◽

Histopathological Examination ◽

Granulomatous Inflammation ◽

Clinical Problem ◽

Pleural Biopsy ◽

Medical College ◽

Fluid Analysis ◽

Common Diagnosis ◽

Common Causes ◽

Exudative Pleural Effusion

Pleural effusion is a common clinical problem in developed as well as developing countries. Tuberculosis and malignancy are common causes of exudative pleural effusion with lymphocytic predominance`. It is very difficult to diagnose the underlying cause by clinical, radiological or even pleural fluid analysis. These cases usually require pleural biopsy for definitive diagnosis2. Pleural biopsy is a safe ad reliable procedure ad is recomended to perform in all cases of exudative pleural effusion. Objective of this study was to list the frequency of patients with lymphocytic exudative pleural effusion diagnosed on pleural biopsy. This study was conducted at the Institute of Chest Medicine Mayo Hospital Lahore. A total of 50 patients, who fulfilled the criteria, were included in this study and underwent closed pleural biopsy. These were then investigated by histopathology. Histopathological examination of pleural biopsy was performed by department of pathology King Edwerd Medical College Lahore. A total of 5 0 patients underwent; closed pleural biopsy. Adequate pleural tissue was obtained in 30 patients (60% of cases) the most common diagnosis made was granulomatous inflammation most likely tuberculosis. Histopathological evaluation of pleural biopsy specimens can lead to diagnosis in 46% of patients with exudative lymphocytic pleural effusion.

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Unusual location of tuberculosis: laryngeal form

Biomedical and Translational Science ◽

10.33425/2768-4911.1001 ◽

2021 ◽

Vol 1 (1) ◽

Author(s):

Mouna Lyoubi ◽

Bushra Abdulhakeem ◽

Hicham Lyoubi ◽

Sanaa mellouk ◽

Youssef Oukessou ◽

...

Keyword(s):

Weight Loss ◽

Direct Laryngoscopy ◽

Histopathological Examination ◽

Granulomatous Inflammation ◽

Acid Fast Bacillus ◽

Common Symptom ◽

Multiple Biopsies ◽

Lymph Node Tuberculosis ◽

The Right ◽

Laryngeal Tuberculosis

Introduction: Tuberculosis is a specific infectious disease caused by a mycobacterium: Koch's bacillus. In Morocco, the lung’s lesion is the most common site 52%, however lymph node tuberculosis is the most frequent extrapulmonary form. Laryngeal tuberculosis is rare. We present the case of a young man with a laryngeal location. Presentation of case: A 25-years-old young man, with 10-years history of alcohol and smoking consumption, was presented to our ENT department with a permanent dysphonia and dyspnea on exertion, the patient had fever and weight loss estimated to 15 kg. Clinical examination found a cachectic patient with a 38.5 ° C of temperature, without any palpable cervical mass or lymphadenopathy. A nasofibroscopy was performed showing a right vocal cord’s lesion. We performed a cervical CT scan revealing a process of the glottic and supraglottic level. Direct laryngoscopy was performed, objectifying ulcerative mass budding from the right vocal cord. Histopathological examination revealed a tuberculoid granuloma without caseating necrosis. Discussion and conclusion: Laryngeal tuberculosis is a rare and frequently under-recognized disease. It typically affects adults in the fifth decade. Literature reports dysphonia to be the most common symptom, followed by weight loss, cough, dysphagia, and odynophagia. Direct laryngoscopy allows direct visualization of the endolaryngeal lesions and performing multiple biopsies. Histopathological examination may identify granulomatous inflammation, caseating granulomas, and acid fast bacillus. However, the presence of pseudoepitheliomatous hyperplasia, which mimics squamous cell carcinoma, can make the diagnosis difficult. The pharmacologic treatment is the same as for the pulmonary forms, and results are generally excellent. Surgical intervention is reserved for those cases of airway compromise.

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Clinical profile of rhinosporidiosis in a tertiary care center of an endemic area

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20181382 ◽

2018 ◽

Vol 4 (3) ◽

pp. 659 ◽

Cited By ~ 2

Author(s):

Suneer R. ◽

Sivasankari L.

Keyword(s):

Tamil Nadu ◽

Endemic Area ◽

Histopathological Examination ◽

Care Center ◽

Tertiary Care ◽

Granulomatous Inflammation ◽

Clinical Profile ◽

Medical College ◽

Male Preponderance ◽

A Prospective Study

Background: Rhinosporidiosis is a chronic granulomatous inflammation caused by Rhinosporidium seeberi. It is water borne disease endemic in Kanyakumari district of South India. The objective of the study was to study the clinical profile of rhinosporidiosis in an endemic area of Kanyakumari districtMethods: This is a prospective study of 50 surgically treated cases of rhinosporidiosis carried out in the department of ENT, Kanyakumari Government Medical College from January 2016 to December 2017. All were diagnosed on clinical basis and were treated by excision and electrocautery of the base. The specimens were sent for histopathological examination. Results: The cases in this study were in the age group between 6 to 70 years. Of these 38 were males and 12 were females indicating a male preponderance. The main presenting symptom was epistaxis in about 80% cases. Nose is the common site involved. Extra nasal spread is common in recurrent cases.Conclusions: The study reflects the endemicity of this disease in Kanyakumari district of Tamil Nadu. High incidence is noted in those bathing in ponds. Extra nasal spread is common in recurrent cases and raising health awareness will go a long way in decreasing its incidence.

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Medicolegal Autopsy: Histopathological Examination of Medicolegal Autopsy Cases and Its Correlation with Causes of Death

10.53350/pjmhs211551495 ◽

2021 ◽

Vol 15 (5) ◽

pp. 1495-1497

Author(s):

S. S. A. Naqvi ◽

Gulshad . ◽

K. Sheikh ◽

I. Wagan ◽

A. Maher ◽

...

Keyword(s):

Cause Of Death ◽

Traffic Accidents ◽

Causes Of Death ◽

Histopathological Examination ◽

Histopathological Analysis ◽

Common Cause ◽

Medical College ◽

Medicolegal Autopsy ◽

The Brain ◽

Keywords Histopathology

Objective: The aim of this study is to determine the histopathological examination of medicolegal autopsy cases and its correlation with causes of death. Study Design: Retrospective/observational Place and Duration: This study was conducted at department of Pathology, Khairpur Medical College Khairpur Mir's for duration of eight months from 15thMay, 2020 to 15thJanuary, 2021. Methods: Hundred cases of both genders were presented in this study. Cases were aged between 15-75 years. Cases detailed demographics age, sex and body mass index were calculated after taking informed written consent from authorities. Autopsy laboratory was used to take medicolegal autopsies of enrolled cases. 10% formalin solution was used for histopathological examination of all the specimens. In the course of the post-mortem investigation we examined the histopathology results for five major organs, such as the brain, heart, lung, liver and kidneys and compared them with gross anatomical results. Complete data was analyzed by SPSS 24.0 version. Results: 62 (62%) cases were males and 38 (38%) patients were females. Mean age of the participants were 30.52±13.17 years with mean BMI 24.52±16.21kg/m2. Most of the participants 40 (40%) were aged between 25-35 years of age followed by 27 (27%) were aged between 36-45 years. Most of the participants 70 (70%) were from urban area and the rest were 30 (30%) from rural area. Instant death was the most common cause found in 35 (35%) cases, followed by traffic accidents 24 (24%) cases. Most frequent effected organs were lung 29%, heart 26%, liver 21% and brain 18%. In lungs pneumonia was the most common effected pathology among 20 (68.97%) and in heart atherosclerosis was the most common effected pathology among 21 (80.77%). Conclusion: In medicolegal autopsy cases, histopathological analysis may be regarded as a useful method. The most common organ in these cases were the heart, liver and lungs. In certain cases, the histopathological exam of these bodies has been useful in identifying the cause of death. Often pathological results included pneumonia, atherosclerosis and congestion. Keywords: Histopathology, Medicolegal, Cause of death, Autopsy

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Clinical and histopathological analysis of the patients undergoing appendectomy

Journal of Pathology of Nepal ◽

10.3126/jpn.v8i2.20862 ◽

2018 ◽

Vol 8 (2) ◽

pp. 1337-1340

Author(s):

Kamal Koirala ◽

Shiva Raj KC ◽

Ganesh Simkhada ◽

Rupesh Mukhiya ◽

Nisheem Pokharel ◽

...

Keyword(s):

Acute Appendicitis ◽

Histopathological Examination ◽

Diagnostic Tools ◽

Histopathological Analysis ◽

Negative Appendectomy ◽

Alvarado Score ◽

Female Ratio ◽

Medical College ◽

Clinical Scoring ◽

Modified Alvarado Score

Background: Acute appendicitis is one of the most common surgical emergencies, but the diagnosis is difficult even with the sophisticated diagnostic tools. The aim of this study is to analyze the clinical and histopathological features of acute appendicitis and to see how reliable the clinical scoring system modified Alvarado score in our setup.Materials and Methods: This was a retrospective observational study of patients who underwent appendectomy at KIST Medical College and Teaching Hospital during two years. The clinical characteristics of the patients in terms of modified Alvarado scoring were outlined. The diagnosis of acute appendicitis was confirmed by histopathological examination. The data were tabulated in MS-Excel and statistically analyzed using SPSS statistics software, version 21.Results: Among 118 patients, who underwent appendectomy, 69 were male and 49 were female with male to female ratio of 1.41:1 and mean age of 27.46±12.724 years.The clinical diagnosis of acute appendicitis was more likely (MAS 7-9) in 56 patients, less likely (4–6) in 44 patients and unlikely (MAS 1-3) in 18 patients. The highest incidence of acute appendicitis was observed in 19-40 years and the lowest incidence in 61 years or above. After histopathological examination, 52 patients out of 56 in the more likely group had acute appendicitis and 4 patients had non-inflamed appendices. 7 patients out of 62 in the less likely and unlikely groups had acute appendicitis and 55 patients had non-inflamed appendices. The overall negative appendectomy rate was 9.32 percent.Conclusion: Our clinical practice of using modified Alvarado score in the diagnosis of acute appendicitis is effective, easy and non-invasive.

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Acute Spontaneous Multiple Ileal Tuberculosis Perforation: A Case Report

Bangladesh Journal of Infectious Diseases ◽

10.3329/bjid.v3i2.33835 ◽

2017 ◽

Vol 3 (2) ◽

pp. 52-54

Author(s):

Md Aminullah ◽

Fahmida Akter Rima ◽

Jamal Abdul Naser ◽

Farzana Kabir ◽

Waliullah Fuad ◽

...

Keyword(s):

Lymph Node ◽

Terminal Ileum ◽

Histopathological Examination ◽

Good Condition ◽

Intestinal Tuberculosis ◽

Granulomatous Inflammation ◽

Exploratory Laparotomy ◽

Excisional Biopsy ◽

Free Perforation ◽

Diffuse Abdominal Pain

A 18 years old boy presented with severe diffuse abdominal pain, constipation, abdominal distention, fever and diagnosed as a case of perforation as free gas noted under both dome of the diaphragm. After resuscitation, exploratory laparotomy was done and diagnosed as a case of multiple spontaneous leaky perforations of jejunum and ileum 25 to 30 cm from duodeno-Jejunal flexure (DJ) up to terminal ileum. Peritoneal toileting and excisional biopsy of the mesenteric lymph node were done. Operative and postoperative period were uneventful. Histopathological examination of the resected lymph node revealed granulomatous inflammation compatible with tuberculosis. Anti-tubercular therapy was started and continued for 6 months. Patient was discharged on the 12th postoperative day in a good condition. At 3 months of follow up the patient was asymptomatic and thriving well. Free perforation is one of the most feared complications of the intestinal tuberculosis. The terminal ileum is the most common site of perforation, while the majority of (90%) perforations are solitary. Bangladesh Journal of Infectious Diseases 2016;3(2):52-54

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Primary Cutaneous Granulomatous Phlebitis of the External Jugular Vein

Phlebology The Journal of Venous Disease ◽

10.1177/026835550201600309 ◽

2002 ◽

Vol 16 (3) ◽

pp. 125-127

Author(s):

S. Shetty ◽

S. Gupta ◽

P. Makhija ◽

S. Hasan

Keyword(s):

Jugular Vein ◽

Inflammatory Diseases ◽

Histopathological Examination ◽

Granulomatous Inflammation ◽

Neck Surgery ◽

Neck Mass ◽

External Jugular Vein ◽

College Hospital ◽

Medical College ◽

The Right

Design: Case report. Setting: Department of Otolaryngology and Head and Neck Surgery, St. John's Medical College Hospital, India. Patient: A 22-year-old man with a cord-like neck mass of 6 months' duration. Investigations and intervention: Investigations included Doppler ultrasound of the neck, which showed thrombosis of the right external jugular vein. Wedge biopsy revealed a granulomatous inflammation with focal necrosis completely replacing the vessel. Serological testing for vasculitides was negative. Transcervical excision of the vein was carried out after identifying normal vessel distally and proximally. Histopathological examination of the vein proved the lesion consistent with primary cutaneous granulomatous phlebitis (PCGP). Conclusion: Isolated venous inflammatory diseases with neither identifiable active vasculitis nor arteritis are rarely seen. PCGP is distinctly unusual. We report a case of PCGP of the external jugular vein presenting as an elongated cord-like nodular lesion in the lateral neck of insidious onset.

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Spectrum of Lesions in the Fallopian Tubes – A Histopathogical Study

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i57b34059 ◽

2021 ◽

pp. 297-301

Author(s):

Maanasa Palani ◽

Volga Harikrishnan

Keyword(s):

Fallopian Tube ◽

Histopathological Examination ◽

Reproductive Age ◽

Histopathological Analysis ◽

Clinical Parameters ◽

Age Group ◽

Fallopian Tubes ◽

Pathological Lesions ◽

Medical College ◽

Reproductive Age Group

Introduction: The Fallopian tubes are a pair of narrow tubular structures connecting the ovary and the uterus. It is usually the site of fertilization and plays a very important role in the fusion of the sperm and ovary and helps in movement of the fertilized zygote to the uterus. Even though being an organ of very small size the importance of the variety of lesions occurring in the fallopian tubes is often not considered. Biopsies of the fallopian tubes are taken to show the different lesions found in the tubes. Aim: The main aim of the study is to study the spectrum of lesions occurring in the fallopian tubes and correlation of these findings with its clinical parameters. Study Design: This is a retrospective descriptive study Place and Duration of Study: Department of Pathology, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences, Thandalam, Chennai between June 2019- December 2019. Methodology: A retrospective study of all the fallopian tube specimens sent for routine histopathological analysis over a period of 6 months was carried out. The different pathological lesions were observed from the relevant clinical data and the correlation with its clinical parameters was done. Results: A sample size of 77 specimens was collected among which the commonest age group which was found to have the highest number of lesions was between 26-30 years. This was found to be in correlation to the reproductive age group of women. The most common form of pathological lesion observed was ectopic pregnancy (about 46% of total pathological lesions), followed by Paratubal cysts (23%), Hydrosalpinx (15%) and Hematosalpinx (8%). Cystadenoma was the only benign tumor observed in this study and constituted 8% of the total pathological lesions. Conclusion: This study shows the importance of histopathological examination of all fallopian tube specimens with or without abnormal findings.

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TO FIND OUT ELECTRO-CARDIOGRAPHIC CHANGES & ECHO CHANGES IN ALUMINIUM PHOSPHIDE AND ETHYLENE DIBROMIDE POISONING

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v4i10.1465 ◽

2020 ◽

Vol 4 (10) ◽

Author(s):

Hemant Nargawe ◽

Sumeet Sisodiya

Keyword(s):

Biochemical Analysis ◽

Histopathological Examination ◽

Common Finding ◽

Histopathological Changes ◽

Ethylene Dibromide ◽

Medical College ◽

Aluminium Phosphide ◽

Urine Examination ◽

Cardiovascular Involvement ◽

Careful Clinical Examination

Background & Method: The study was conducted in the Department of Medicine Shyam Shah Medical College and Associated Sanjay Gandhi Memorial Hospital, Rewa (M.P). History was followed by a careful clinical examination i.e. cardiovascular, respiratory and gastrointestinal and nervous system. Investigations had done included routine haematological examination, Biochemical analysis, urine examination, ECG, 2 D. Echo & Histopathological examination was done. Result: ST-T changes were most common finding in Aluminium phosphide poisoning in relation to mortality. However hyperkalemia was the most ominous finding associated with 100% mortality, ECG finding in EDB was normal ECG. The most ominous finding was arrhythmia which was associated with 100% mortality. Survivors of ethylene dibromide poisoning echocardiography was normal in 11 (84.61%) followed by pericardial effusion in 2 (15.38%) patients. Conclusion: Noteworthy finding was absence of correlation between cardiovascular involvement, histopathological changes and ECG findings. It was seen that even if ECG showed normal pattern there were significant histopathological changes in heart. Keywords: electro-cardiographic, Aluminium phosphide, ethylene dibromide & poisoning.

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