Magnetic device for closing skin wounds

The attempt to repair skin wounds dates back many years. We have observed bone fragments for making needles, hair, fibers, and animal tissues as sutures and even applying sensors to accelerate the healing process throughout history. Despite all the developments, the need for a qualified professional and prior local anesthesia to perform the suture still represent obstacles. The present study aimed to create 3D printing pieces containing N42 neodymium magnets to be fixed to the skin with adhesive tape to promote skin wounds' closure without the need for anesthesia. A descriptive, experimental study was carried out, divided into the Patent search, Ideation and creation, 3D Modeling, 3D printing of structural parts, Assembly, and Testing on artificial skin. ABSplus® plastic parts were created through 3D printing that received N42 neodymium magnets and the application of a double-sided adhesive to attach to the skin. A perilesional arrangement was simulated with the pieces created using an artificial skin model (EasySuture® Standart) after making the incision. After applying the pieces containing N42 neodymium, there was a perfect coaptation of the lesion's edges without detecting interspersed spaces in the longitudinal axis of the incision. The research resulted in creating a prototype that needs improvements and industrial adaptations for viable use in surgical practice.

Download Full-text

Evaluation of the Ability to Accurately Produce Angular Details by 3D Printing of Plastic Parts

Machines ◽

10.3390/machines9080150 ◽

2021 ◽

Vol 9 (8) ◽

pp. 150

Author(s):

Andrei Marius Mihalache ◽

Gheorghe Nagîț ◽

Laurențiu Slătineanu ◽

Adelina Hrițuc ◽

Angelos Markopoulos ◽

...

Keyword(s):

3D Printing ◽

Point Of View ◽

Vertex Angle ◽

Function Type ◽

Constant Height ◽

3D Printers ◽

3D Printed ◽

Mathematical Processing ◽

Plastic Parts

3D printing is a process that has become widely used in recent years, allowing the production of parts with relatively complicated shapes from metallic and non-metallic materials. In some cases, it is challenging to evaluate the ability of 3D printers to make fine details of parts. For such an assessment, the printing of samples showing intersections of surfaces with low angle values was considered. An experimental plan was designed and materialized to highlight the influence of different factors, such as the thickness of the deposited material layer, the printing speed, the cooling and filling conditions of the 3D-printed part, and the thickness of the sample. Samples using areas in the form of isosceles triangles with constant height or bases with the same length, respectively, were used. The mathematical processing of the experimental results allowed the determination of empirical mathematical models of the power-function type. It allowed the detection of both the direction of actions and the intensity of the influence exerted by the input factors. It is concluded that the strongest influence on the printer’s ability to produce fine detail, from the point of view addressed in the paper, is exerted by the vertex angle, whose reduction leads to a decrease in printing accuracy.

Download Full-text

Topological design for 3D-printing of carbon fibre reinforced composite structural parts

Composites Science and Technology ◽

10.1016/j.compscitech.2020.108644 ◽

2021 ◽

Vol 204 ◽

pp. 108644

Author(s):

Yuan Chen ◽

Lin Ye

Keyword(s):

3D Printing ◽

Carbon Fibre ◽

Topological Design ◽

Reinforced Composite ◽

Structural Parts

Download Full-text

3D Printing of Artificial Skin Patches with Bioactive and Optically Active Polymer Materials for Anti-Infection and Augmenting Wound Repair

Materials Horizons ◽

10.1039/d1mh00508a ◽

2021 ◽

Author(s):

Hao Zhao ◽

Jingwen Xu ◽

Haitao Yuan ◽

Endong Zhang ◽

Nan Dai ◽

...

Keyword(s):

3D Printing ◽

Human Skin ◽

Wound Repair ◽

Optically Active ◽

The Body ◽

Polymer Materials ◽

Artificial Skin ◽

Optically Active Polymer ◽

Cell Affinity

Inspired by the skin biofunction of protecting the body from microorganism invasion, artificially manufacturing human skin in vitro with promising antibacterial capability and cell affinity is urgently required in wound...

Download Full-text

Efficiency of Enzymatic Debridement in the Healing Process of Chronic Wounds in Small Animal Practice

Folia Veterinaria ◽

10.1515/fv-2017-0006 ◽

2017 ◽

Vol 61 (1) ◽

pp. 38-42 ◽

Cited By ~ 1

Author(s):

L. Hamilton ◽

M. Kožár

Keyword(s):

Chronic Wounds ◽

Healing Process ◽

Small Animal ◽

Skin Defect ◽

Skin Wounds ◽

Macroscopic Appearance ◽

Enzyme Preparations ◽

Chronic Skin ◽

The Individual ◽

Enzymatic Debridement

Abstract Skin wounds are a common presentation in small animal practice. These wounds may be acute or chronic with a complicated healing process. An important aspect of the healing of wounds is debridement which may be carried out by surgical, autolytic, mechanical or enzymatic methods. The debridement method is chosen according to the individual skin defect and influenced by factors such as wound size and location, the age of the wound, and the presence of infection or exudate. Enzymatic debridement is a method that is not commonly used in veterinary practice, and involves the use of enzyme preparations to remove necrotic tissue from a wound. The aim of this study was to investigate the effects of the enzymatic ointment collagenase as a method of debridement, and its effect on the macroscopic appearance of chronic skin wounds in cats and dogs. We observed that the application of Iruxol Mono directly to the wound changes the progress of the healing process, with no obvious adverse effects. The time of healing of chronic wounds was decreased and healthy granulation tissue was developed within a couple of days after application of the ointment. Enzymatic debridement appears to be a promising method of debridement for use in chronic wounds, and should be considered in cases where more conventional methods of debridement are ineffective or unsuitable.

Download Full-text

Experimental skin wound treatment with Copaifera langsdorffii Desf Kuntze (Leguminosae) extract and oil-resin in horses

Brazilian Journal of Veterinary Research and Animal Science ◽

10.11606/issn.1678-4456.bjvras.2020.166095 ◽

2020 ◽

Vol 57 (3) ◽

pp. e166095

Author(s):

Débora Perrone Kauer ◽

Juliana de Moura Alonso ◽

Lucas Fernando Sergio Gushiken ◽

Marivane Lemos ◽

Carlos Roberto Padovani ◽

...

Keyword(s):

Wound Healing ◽

Small Area ◽

Healing Process ◽

Skin Lesions ◽

Lumbar Region ◽

Skin Wounds ◽

Native Plant ◽

Chronic Inflammatory Response ◽

Significant Difference ◽

Copaifera Langsdorffii

Copaifera langsdorffii is a Brazilian native plant that is used for wound healing or as an anti-inflammatory agent. Non-healing wounds are an important health problem, particularly in horses, because they can cause the animal invalidity or even lead to death. In addition, horses respond to skin wounds with chronic inflammatory response and intense wound granulation, thereby delaying the healing process. By this way, our aim was to evaluate the healing potential of Copaifera langsdorffii hydroalcoholic extract (HE) and oil-resin creams (OR) in horse skin wounds. Four wounds were performed bilaterally in the lumbar region of six horses with a 2 cm punch and treated daily with the respective treatments: saline solution, vehicle, 10% HE creams or 10% OR cream. Daily planimetry analyses were performed to measure the wound area and clinical parameters. In four different experimental periods (3, 7, 14 and 21 d), wound biopsies were removed and used for microscopic analyses. SS wounds presented a significant small area at day 3 and 7, OR wounds presented significant small area in comparison with HE at 14 d, and no significant difference was observed between treatments at 21 d. A better microscopic and clinical healing activity of HE and OR was identified in comparison with the controls. The OR group showed better healing quality, specifically after 7 d of treatment. Therefore, Copaifera langsdorffii formulations demonstrated their wound healing potential in horse skin lesions, exhibiting an improvement of the macro- and microscopic parameters.

Download Full-text

Analysis of the healing process in superficial skin wounds irradiated with a blue-LED photocoagulator

2014 Fotonica AEIT Italian Conference on Photonics Technologies ◽

10.1109/fotonica.2014.6843965 ◽

2014 ◽

Author(s):

Francesca Rossi ◽

Francesca Tatini ◽

Roberto Pini ◽

Riccardo Cicchi ◽

Francesco S. Pavone ◽

...

Keyword(s):

Healing Process ◽

Skin Wounds ◽

Blue Led ◽

Superficial Skin

Download Full-text

Epoxy-Pin External Skeletal Fixation for Management of Open Bone Fractures in Calves and Foals: A Review of 32 Cases

Veterinary and Comparative Orthopaedics and Traumatology ◽

10.1055/s-0039-1678736 ◽

2019 ◽

Vol 32 (03) ◽

pp. 257-268

Author(s):

Hari Aithal ◽

Prakash Kinjavdekar ◽

Abhijit Pawde ◽

Prasoon Dubey ◽

Rohit Kumar ◽

...

Keyword(s):

Bone Fractures ◽

Weight Bearing ◽

Fracture Site ◽

Open Fractures ◽

Adhesive Tape ◽

Stable Fixation ◽

Early Weight Bearing ◽

Pin Fixation ◽

Bone Fragments ◽

The Subject

Objective The aim of this study was to evaluate epoxy-pin external skeletal fixation technique for the treatment of open fractures in calves and foals. Study Design Twenty-eight calves and four foals (weighing 45–105 kg) with fractures distal to the stifle or elbow made the subject for the retrospective study. The pins (2.0–3.0-mm Kirschner wires, crossed at 60–90°) were fixed at least at two locations in both proximal and distal bone fragments as per the case situation. The pins in the same plane were bent (∼2 cm from the skin) towards the fracture site or joint and were joined using an adhesive tape (additional pins used when required) to make a temporary scaffold of connecting bars or rings. Thoroughly mixed epoxy putty was applied along the pin scaffold (the epoxy columns were 20–25 mm diameter) and allowed to set for 45 to 60 minutes. All animals were evaluated based on various clinical and radiographic observations made at regular intervals. Results The epoxy-pin fixation was easy to apply and provided stable fixation of bone as indicated by early weight bearing, and fracture healing within 45 to 60 days (17/32 cases). The functional recovery was good to very good in 14 animals and satisfactory in nine cases by 12 months after removal of the fixator. Conclusions The multiplanar epoxy-pin external skeletal fixation provides stable fixation of unstable open fractures distal to the stifle or elbow joint; hence, it can be used to treat a variety of fractures in calves and foals weighing up to approximately 100 kg, especially open infected fractures of lower limb, which are difficult to treat by conventional techniques.

Download Full-text

Verapamil, a Calcium-Channel Blocker, Improves the Wound Healing Process in Rats with Excisional Full-Thickness Skin Wounds Based on Stereological Parameters

Advances in Skin & Wound Care ◽

10.1097/01.asw.0000488666.03896.e6 ◽

2016 ◽

Vol 29 (8) ◽

pp. 371-374 ◽

Cited By ~ 5

Author(s):

Soheil Ashkani-Esfahani ◽

Omid Koohi Hosseinabadi ◽

Parinaz Moezzi ◽

Yalda Moafpourian ◽

Sina Kardeh ◽

...

Keyword(s):

Wound Healing ◽

Calcium Channel ◽

Calcium Channel Blocker ◽

Channel Blocker ◽

Healing Process ◽

Wound Healing Process ◽

Skin Wounds ◽

Full Thickness ◽

Full Thickness Skin ◽

Thickness Skin

Download Full-text

Algorithm for Detecting and Solving the Problem of Under-Filled Pointed Ends Based on 3D Printing Plastic Droplet Generation

Volume 2A: Advanced Manufacturing ◽

10.1115/imece2014-36573 ◽

2014 ◽

Cited By ~ 1

Author(s):

Jelena Prša ◽

Franz Irlinger ◽

Tim C. Lueth

Keyword(s):

3D Printing ◽

Droplet Generation ◽

Generation Process ◽

Critical Area ◽

Final Shape ◽

Angle Bisector ◽

Critical Areas ◽

3D Printed ◽

Plastic Parts ◽

Initial Geometry

In this paper the problem of under-filled pointed ends is introduced and mathematically defined. To tackle this problem, we present a new algorithm that detects and fills the critical areas, which arise at the 3D printed plastic parts. While printing the contours and/or infill lines, due to the limitations based on the width of the extruded material, narrow edges and pointed ends remain improperly filled. This eventually results in 3D printed objects with the final geometry that differs greatly from the initial geometry. This paper presents the fundamentals for solving the problem of 3D printing of geometries which contain narrow pointed ends. The critical area of the pointed ends is mathematically defined and, depending on the angle, the formulae for the calculation of under-filled and over-filled areas are given. The newly developed algorithm, based on the 3D Printing plastic droplet generation process, assures that the droplets of the repeating contours are placed at the edges of the contour-segments and by that minimises the potential under-fills. Furthermore, an additional number of droplets is defined, that are either printed in or removed from the under-filled areas in the angle bisector. The proposed algorithm is applied on parts, whose geometry describes pointed ends. The final 3D printed parts are very appealing and their shape resembles the original geometry more than the final shape of the parts without applying the algorithm.

Download Full-text