Functional methods of investigation of respiratory system in asthma

Medical alphabet ◽

10.33667/2078-5631-2021-15-14-20 ◽

2021 ◽

pp. 14-20

Author(s):

O. I. Savushkina ◽

A. V. Cherniak ◽

E. V. Kryukov

Keyword(s):

Respiratory System ◽

Stress Testing ◽

Bronchial Hyperreactivity ◽

Impulse Oscillometry ◽

Body Plethysmography ◽

Provocative Test ◽

Functional Methods ◽

Test Stress

The article deals with the application of functional methods for the study of the respiratory system, such as spirometry, bronchodilatation test, stress testing to detect bronchial hyperreactivity, provocative test with metacholine, impulse oscillometry, body plethysmography for the diagnosis, following up and prediction of the course of asthma.

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Respiratory system impedance with impulse oscillometry in Parkinson's disease: Relation with disease severity

10.1183/13993003.congress-2016.pa2262 ◽

2016 ◽

Author(s):

Meghashree Sampath ◽

Anjana Talwar ◽

Ashok Jaryal ◽

Vinay Goyal ◽

Achal Srivastava ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Disease Severity ◽

Respiratory System ◽

Impulse Oscillometry

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Flow-Volume Parameters in COPD Related to Extended Measurements of Lung Volume, Diffusion, and Resistance

Pulmonary Medicine ◽

10.1155/2013/782052 ◽

2013 ◽

Vol 2013 ◽

pp. 1-10 ◽

Cited By ~ 19

Author(s):

Linnea Jarenbäck ◽

Jaro Ankerst ◽

Leif Bjermer ◽

Ellen Tufvesson

Keyword(s):

Lung Function ◽

Forced Expiratory Volume ◽

Flow Volume ◽

Impulse Oscillometry ◽

Body Plethysmography ◽

Additional Information ◽

Single Breath ◽

Gold Stage ◽

Copd Patients ◽

Helium Dilution

Classification of COPD into different GOLD stages is based on forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) but has shown to be of limited value. The aim of the study was to relate spirometry values to more advanced measures of lung function in COPD patients compared to healthy smokers. The lung function of 65 COPD patients and 34 healthy smokers was investigated using flow-volume spirometry, body plethysmography, single breath helium dilution with CO-diffusion, and impulse oscillometry. All lung function parameters, measured by body plethysmography, CO-diffusion, and impulse oscillometry, were increasingly affected through increasing GOLD stage but did not correlate with FEV1within any GOLD stage. In contrast, they correlated fairly well with FVC%p, FEV1/FVC, and inspiratory capacity. Residual volume (RV) measured by body plethysmography increased through GOLD stages, while RV measured by helium dilution decreased. The difference between these RV provided valuable additional information and correlated with most other lung function parameters measured by body plethysmography and CO-diffusion. Airway resistance measured by body plethysmography and impulse oscillometry correlated within COPD stages. Different lung function parameters are of importance in COPD, and a thorough patient characterization is important to understand the disease.

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Reference values for respiratory system impedance using impulse oscillometry in school-aged children in Korea

Korean Journal of Pediatrics ◽

10.3345/kjp.2007.50.9.862 ◽

2007 ◽

Vol 50 (9) ◽

pp. 862 ◽

Cited By ~ 2

Author(s):

Young Sun Wee ◽

Hyoung Yun Kim ◽

Da Wun Jung ◽

Hye Won Park ◽

Yoon Ho Shin ◽

...

Keyword(s):

Reference Values ◽

Respiratory System ◽

Impulse Oscillometry ◽

School Aged Children

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Within-Breath Oscillatory Mechanics in Horses Affected by Severe Equine Asthma in Exacerbation and in Remission of the Disease

Animals ◽

10.3390/ani12010004 ◽

2021 ◽

Vol 12 (1) ◽

pp. 4

Author(s):

Luca Stucchi ◽

Francesco Ferrucci ◽

Michela Bullone ◽

Raffaele L. Dellacà ◽

Jean Pierre Lavoie

Keyword(s):

Severe Asthma ◽

Respiratory System ◽

Clinical Remission ◽

Matched Control ◽

Flow Limitation ◽

Impulse Oscillometry ◽

Expiratory Flow Limitation ◽

The Mean ◽

The Difference ◽

And Control

Oscillometry is a technique that measures the resistance (R) and the reactance (X) of the respiratory system. In humans, analysis of inspiratory and expiratory R and X allows to identify the presence of tidal expiratory flow limitation (EFLt). The aim of this study was to describe inspiratory and expiratory R and X measured by impulse oscillometry system (IOS) in horses with severe asthma (SEA) when in clinical remission (n = 7) or in exacerbation (n = 7) of the condition. Seven healthy, age-matched control horses were also studied. Data at 3, 5, and 7 Hz with coherence > 0.85 at 3 Hz and >0.9 at 5 and 7 Hz were considered. The mean, inspiratory and expiratory R and X and the difference between inspiratory and expiratory X (ΔX) were calculated at each frequency. The data from the three groups were statistically compared. Results indicated that in horses during exacerbation of severe asthma, X during expiratory phase is more negative than during inspiration, such as in humans in presence of EFLt. The evaluation of X during inspiration is promising in discriminating between horses with SEA in remission and control horses.

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The Impulse oscillometry in the diagnosis of respiratory mechanics defects in elderly patients with lung cancer

MedAlliance ◽

10.36422/23076348-2020-8-1-69-74 ◽

2020 ◽

Vol 8 (1) ◽

pp. 69-74

Keyword(s):

Lung Cancer ◽

Elderly Patients ◽

Respiratory Mechanics ◽

Pulmonary Function Tests ◽

The Elderly ◽

Impulse Oscillometry ◽

Body Plethysmography ◽

Quiet Breathing ◽

Cross Sectional ◽

Lung Cancer Patients

Traditional pulmonary function tests (PFTs) (spirometry, body plethysmography, diffusion test) are quite time-consuming and difficult to perform methods, especially in the elderly patients. Impulse oscillometry (IOS) is advantageous in that all measurements are carried out with quiet breathing for 30–60 s and do not require the active participation of the patient. Objective: to compare IOS with traditional PFTs and to study its capabilities in the diagnosis of respiratory disorders in patients with lung cancer in the elderly patients. Materials and methods: an observational cross-sectional cohort study was performed. The study included 57 patients (55 (97%) male and 2 (3%) female, median age 69 (65–73) years). Smokers or ex-smokers accounted for 93% (39% and 54%, respectively), non-smokers — 7%. Central lung cancer was diagnosed in 22 (39%), peripheral lung cancer — in 35 (61%) patients. Results: ventilation disorders were detected in 54 (95%) patients, including 52 (96%) of obstructive, 1 — restrictive and 1 — mixed respiratory defects. Lung diffusion capacity was reduced in 30 (53%) patients. According to IOS data, deviations from the norm of R5, X5, AX (R5–R20) were detected in 43 (75%) patients. There was a statistically significant correlation between the parameters of the IOS with parameters of spirometry and most of the parameters of body plethysmography. Conclusion: IOS can be used to assess respiratory mechanics in elderly lung cancer patients.

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Reference values for respiratory system impedance by using impulse oscillometry in children aged 2-11 years

Clinical Physiology and Functional Imaging ◽

10.1111/j.1475-097x.2006.00682.x ◽

2006 ◽

Vol 26 (4) ◽

pp. 247-250 ◽

Cited By ~ 57

Author(s):

M. Dencker ◽

L. P. Malmberg ◽

S. Valind ◽

O. Thorsson ◽

M. K. Karlsson ◽

...

Keyword(s):

Reference Values ◽

Respiratory System ◽

Impulse Oscillometry

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Determining respiratory system resistance and reactance by impulse oscillometry in obese individuals

Jornal Brasileiro de Pneumologia ◽

10.1590/s1806-37132015000004517 ◽

2015 ◽

Vol 41 (5) ◽

pp. 422-426 ◽

Cited By ~ 9

Author(s):

Cláudio Gonçalves de Albuquerque ◽

Flávio Maciel Dias de Andrade ◽

Marcus Aurélio de Almeida Rocha ◽

Alina Farias França de Oliveira ◽

Waldemar Ladosky ◽

...

Keyword(s):

Body Mass Index ◽

Morbid Obesity ◽

Body Mass ◽

Respiratory System ◽

Severe Obesity ◽

Impulse Oscillometry ◽

Respiratory System Resistance ◽

The Difference

Objective: To evaluate peripheral respiratory system resistance and reactance (Rrs and Xrs, respectively) in obese individuals. Methods: We recruited 99 individuals, dividing them into four groups by body mass index (BMI): < 30.0 kg/m2 (control, n = 31); 30.0-39.9 kg/m2 (obesity, n = 13); 40.0-49.9 kg/m2 (severe obesity, n = 28); and ≥ 50.0 kg/m2 (morbid obesity, n = 13). Using impulse oscillometry, we measured total Rrs, central Rrs, and Xrs. Peripheral Rrs was calculated as the difference between total Rrs and central Rrs. All subjects also underwent spirometry. Results: Of the 99 individuals recruited, 14 were excluded because they failed to perform forced expiratory maneuvers correctly during spirometry. The individuals in the severe obesity and morbid obesity groups showed higher peripheral Rrs and lower Xrs in comparison with those in the two other groups. Conclusions: Having a BMI ≥ 40 kg/m2 was associated with a significant increase in peripheral Rrs and with a decrease in Xrs.

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Diagnosis of small airway dysfunction in patients with chronic obstructive pulmonary disease

Almanac of Clinical Medicine ◽

10.18786/2072-0505-2020-48-019 ◽

2020 ◽

Vol 48 (5) ◽

pp. 307-315

Author(s):

A. V. Cherniak ◽

O. I. Savushkina ◽

T. L. Pashkova ◽

E. V. Kryukov

Keyword(s):

Chronic Obstructive Pulmonary Disease ◽

Pulmonary Disease ◽

Vital Capacity ◽

Small Airway ◽

Diagnostic Methods ◽

Chronic Obstructive ◽

Impulse Oscillometry ◽

Body Plethysmography ◽

Obstructive Pulmonary Disease ◽

Copd Patients

Background: Small airway dysfunction (SAD) is a functional hallmark of chronic obstructive pulmonary disease (COPD). However, SAD prevalence and its role in COPD pathophysiology are not yet sufficiently studied.Background: Small airway dysfunction (SAD) is a functional hallmark of chronic obstructive pulmonary disease (COPD). However, SAD prevalence and its role in COPD pathophysiology are not yet sufficiently studied.Aim: To assess the prevalence of SAD in COPD patients by various functional diagnostic methods, such as spirometry, body plethysmography, and impulse oscillometry (IOS).Materials and methods: This was an cross-sectional study. Spirometry, body plethysmography and IOS were used in 132 COPD patients in remission under standard anti-COPD treatments. The presence of SAD was confirmed by at least one of the following criteria or their combination: 1) by spirometry: the difference between vital capacity (VC) and forced vital capacity (FVC) > 10%; 2) the presence of air trapping by body plethysmography; 3) identification of the frequency dependence of the resistive resistance at 5 to 20 Hz (R5 - R20 > 0.07 kPa x s/l), as assessed by IOS.Results: Mean forced expiratory volume in 1 s (FEV1) was 42.9% of predicted. Depending on the severity of the obstruction, the patients were divided into 4 groups: 7 patients (group 1) had the obstruction corresponding to GOLD 1 stage, 37 (group 2) to GOLD 2, 49 (group 3) to GOLD 3, and 39 (group 4) to GOLD 4. SAD was found in 96% of COPD patients, whereas in those with severe obstruction (GOLD 3-4), it was present in 100% of the cases. By spirometry, SAD was identified only in 67% of COPD patients, by body plethysmography in 75% of COPD patients (in those with severe obstruction (GOLD 3 and 4) in 88 and 97%, respectively). With IOS, it was possible to identify SAD in 94% of patients and in 100% of those with severe obstruction (GOLD 3-4).Conclusion: With deterioration of obstructive pulmonary ventilation abnormalities in COPD patients, there is a progressive increase in small airway dysfunction. Impulse oscillometry seems to be the most effective method for diagnosis of small airway dysfunction, as it helped to identify SAD in 94% of COPD patients and in 100% of those with severe and very severe obstruction.

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