scholarly journals suPAR, a Circulating Kidney Disease Factor

2021 ◽  
Vol 8 ◽  
Author(s):  
Changli Wei ◽  
Ryan Spear ◽  
Eunsil Hahm ◽  
Jochen Reiser
Keyword(s):  
Kidney Disease ◽  
Plasminogen Activator ◽  
Blood Circulation ◽  
Urokinase Plasminogen Activator ◽  
Protein Release ◽  
Urokinase Plasminogen Activator Receptor ◽  
Disease States ◽  
Plasminogen Activator Receptor ◽  
Domain Protein ◽  
Disease Factor

Urokinase plasminogen activator receptor (uPAR) is a multifaceted, GPI-anchored three-domain protein. Release of the receptor results in variable levels of soluble uPAR (suPAR) in the blood circulation. suPAR levels have been linked to many disease states. In this mini-review, we discuss suPAR as a key circulating molecule mediating kidney disease with a particular focus on differently spliced isoforms.

scholarly journals Molecular imaging of the urokinase plasminogen activator receptor: opportunities beyond cancer

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
V. M. Baart ◽  
R. D. Houvast ◽  
L. F. de Geus-Oei ◽  
P. H. A. Quax ◽  
P. J. K. Kuppen ◽  
...  
Keyword(s):  
Molecular Imaging ◽  
Plasminogen Activator ◽  
Urokinase Plasminogen Activator ◽  
Urokinase Plasminogen Activator Receptor ◽  
Plasminogen Activator Receptor
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