scholarly journals Decreased Gray-Matter Volume in Insular Cortex as a Correlate of Singers’ Enhanced Sensorimotor Control of Vocal Production

2019 ◽  
Vol 13 ◽  
Author(s):  
Wenda Wang ◽  
Lirao Wei ◽  
Na Chen ◽  
Jeffery A. Jones ◽  
Gaolang Gong ◽  
...  
Keyword(s):  
Gray Matter ◽  
Gray Matter Volume ◽  
Insular Cortex ◽  
Sensorimotor Control ◽  
Vocal Production ◽  
Matter Volume

Gray matter volume of the anterior insular cortex and social networking

2018 ◽  
Vol 526 (7) ◽  
pp. 1183-1194 ◽  
Author(s):  
Alfredo Spagna ◽  
Alexander J. Dufford ◽  
Qiong Wu ◽  
Tingting Wu ◽  
Weihao Zheng ◽  
...  
Keyword(s):  
Social Networking ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Insular Cortex ◽  
Matter Volume ◽  
Anterior Insular Cortex

Contralesional macrostructural plasticity of the insular cortex in patients with glioma

Neurology ◽  
2018 ◽  
Vol 91 (20) ◽  
pp. e1902-e1908 ◽  
Author(s):  
Fabien Almairac ◽  
Hugues Duffau ◽  
Guillaume Herbet
Keyword(s):  
Gray Matter ◽  
Gray Matter Volume ◽  
Region Of Interest ◽  
Insular Cortex ◽  
Low Grade ◽  
Healthy Controls ◽  
Matter Volume ◽  
Patient Groups ◽  
The Right ◽  
High Level

ObjectiveTo assess the homotopic structural plasticity in case of unilateral damage of the insula.MethodsTo detect changes in gray matter volumes of the contralesional insula from structural MRIs, we used voxel-based morphometry (VBM) in a sample of 84 patients with a diffuse low-grade glioma invading the left insula (insL group; n = 47) or the right insula (insR group; n = 37).ResultsThe region of interest–based VBM analysis highlighted a large cluster of voxels with gray matter volume increase in the contralesional insula in both patient groups (k = 2,214 voxels for insL and k = 879 voxels for insR, p < 0.05, family-wise error corrected) compared with 24 age-matched healthy controls. Gray matter volume was increased for the entire insula (t69 = 3.63, p = 0.0016 for insL; t59 = 3.54, p = 0.0024 for insR, Bonferroni corrected), whereas no significant changes were found in 2 control regions for both patient groups. Furthermore, an increase of 24.6% and 31.6% in the gray matter volume was observed in the insula-related VBM cluster for insL and insR patients, respectively, compared with healthy controls (t69 = 7.39, p = 2.59 × 10−10 and t59 = 7.51, p = 3.61 × 10−10).ConclusionsThe reported results demonstrate that slow-growing but massive lesion infiltration of the insula induces marked increase of gray matter volume in the contralateral one. Our findings give support for a homotopic reorganization that might be a physiologic basis for the high level of functional compensation observed in patients with glioma.

scholarly journals Parental Praise Correlates with Posterior Insular Cortex Gray Matter Volume in Children and Adolescents

PLoS ONE ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. e0154220 ◽  
Author(s):  
Izumi Matsudaira ◽  
Susumu Yokota ◽  
Teruo Hashimoto ◽  
Hikaru Takeuchi ◽  
Kohei Asano ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Insular Cortex ◽  
Matter Volume

Gray matter volume reduction reflects chronic pain in trigeminal neuralgia

2012 ◽  
Vol 43 (01) ◽  
Author(s):  
M Obermann ◽  
R Rodriguez-Raecke ◽  
S Nägel ◽  
D Holle ◽  
N Theysohn ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Trigeminal Neuralgia ◽  
Gray Matter ◽  
Gray Matter Volume ◽  
Volume Reduction ◽  
Matter Volume

scholarly journals Topographic patterns of white matter hyperintensities are associated with multimodal neuroimaging biomarkers of Alzheimer’s disease

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Malo Gaubert ◽  
Catharina Lange ◽  
Antoine Garnier-Crussard ◽  
Theresa Köbe ◽  
Salma Bougacha ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
White Matter ◽  
Glucose Metabolism ◽  
Corpus Callosum ◽  
Gray Matter ◽  
Fdg Pet ◽  
White Matter Hyperintensities ◽  
Gray Matter Volume ◽  
Matter Volume

Abstract Background White matter hyperintensities (WMH) are frequently found in Alzheimer’s disease (AD). Commonly considered as a marker of cerebrovascular disease, regional WMH may be related to pathological hallmarks of AD, including beta-amyloid (Aβ) plaques and neurodegeneration. The aim of this study was to examine the regional distribution of WMH associated with Aβ burden, glucose hypometabolism, and gray matter volume reduction. Methods In a total of 155 participants (IMAP+ cohort) across the cognitive continuum from normal cognition to AD dementia, FLAIR MRI, AV45-PET, FDG-PET, and T1 MRI were acquired. WMH were automatically segmented from FLAIR images. Mean levels of neocortical Aβ deposition (AV45-PET), temporo-parietal glucose metabolism (FDG-PET), and medial-temporal gray matter volume (GMV) were extracted from processed images using established AD meta-signature templates. Associations between AD brain biomarkers and WMH, as assessed in region-of-interest and voxel-wise, were examined, adjusting for age, sex, education, and systolic blood pressure. Results There were no significant associations between global Aβ burden and region-specific WMH. Voxel-wise WMH in the splenium of the corpus callosum correlated with greater Aβ deposition at a more liberal threshold. Region- and voxel-based WMH in the posterior corpus callosum, along with parietal, occipital, and frontal areas, were associated with lower temporo-parietal glucose metabolism. Similarly, lower medial-temporal GMV correlated with WMH in the posterior corpus callosum in addition to parietal, occipital, and fontal areas. Conclusions This study demonstrates that local white matter damage is correlated with multimodal brain biomarkers of AD. Our results highlight modality-specific topographic patterns of WMH, which converged in the posterior white matter. Overall, these cross-sectional findings corroborate associations of regional WMH with AD-typical Aß deposition and neurodegeneration.

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