scholarly journals Case Report: Concurrent Resistance and Aerobic Training Regulate Adiponectin Expression and Disease Severity in Multiple Sclerosis: A Case Study

2020 ◽  
Vol 14 ◽  
Author(s):  
Elisa Grazioli ◽  
Ersilia Nigro ◽  
Claudia Cerulli ◽  
Giovanna Borriello ◽  
Annamaria Mancini ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Disease Severity ◽  
Biological Effects ◽  
Moderate Intensity ◽  
Total Serum ◽  
Total Adiponectin ◽  
Starting Point ◽  
The Relationship

Adapted exercise is an effective non-pharmacological tool to improve functional, cognitive, and psychological parameters in multiple sclerosis (MS), in association with increased quality of life (QoL) and decreased disease severity. Adipose tissue, through the production of different adipokines, is involved in regulating energy metabolism and inflammation. Adiponectin, increased in MS, circulates as oligomers of low (LMW), medium (MMW), and high molecular weight (HMW), the latter mediating the main biological effects. The aim of study was to evaluate the effects of 4 months training at moderate intensity [65% heart rate reserve (HRR)] on BMI, adiponectin, and QoL in a volunteer with secondary progressive MS. The parameters were evaluated before (T0), after 4 months training (T1), and 6 months after the end of training (T2); total serum adiponectin and its oligomeric profile were evaluated. We found a reduction in BMI (−0.9%) and FAT (−2.6%), an improvement in perceived QoL and a reduced expression of total adiponectin and HMW oligomers together with decreased MS disability level at T1 measured by EDSS. Despite the limitations of a case study, this represent a starting point to understand the influence of exercise in MS and the relationship with adiponectin expression.

scholarly journals Quality of Life Model in Multiple Sclerosis: Personality, Mood Disturbance, Catastrophizing and Disease Severity

2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Afsaneh Akhani ◽  
Mojtaba Habibi ◽  
Zahra Izadikhah ◽  
Mani B. Monajemi ◽  
Nina Jamshinejad
Keyword(s):  
Quality Of Life ◽  
Multiple Sclerosis ◽  
Disease Severity ◽  
Illness Perception ◽  
Type D Personality ◽  
Mood Disturbance ◽  
Equation Modeling ◽  
Type D ◽  
The Relationship

Objective: The aim of current study was to investigate the interaction between factors such as personality, catastrophizing, mood disturbance and disease severity, which may affect the quality of life in patients with multiple sclerosis. The result of this study can identify the factors that have an impact on quality of life among these patients and hopefully it may lead to improve the services provided for these patients. Design: One hundred and thirteen participants with multiple sclerosis completed the following questionnaires: Type D Personality (DS-14), Hospital Anxiety and Depression (HADS), Illness Perception (Brief-IPQ) and Quality of Life (SF-36). The Expanded Disability Statue Scale (EDSS) assessed disease severity. Main Outcome Measures: Data was analyzed in structural equation modeling. Results: Type D personality was associated with quality of life and the relationship was mediated by disease severity, catastrophizing and mood status. Conclusion: Results showed a significant relationship between Type D personality and QOL. However, when the variables were added to the model, the relationship ceased to exist. These results suggest that personality traits are indirectly associated with QOL, mediated by another variable.

scholarly journals Does Tenure Security Reduce Disaster Risk? A Comparative Study of the Nairobi Settlements of Kibera and Kawangware

2021 ◽  
Author(s):  
Rónán McDermott ◽  
Pat Gibbons ◽  
Dalmas Ochieng ◽  
Charles Owuor Olungah ◽  
Desire Mpanje
Keyword(s):  
Structural Integrity ◽  
Disaster Risk ◽  
Comparative Case Study ◽  
Complex Relationship ◽  
Tenure Security ◽  
Household Level ◽  
Urban Informal Settlements ◽  
The Relationship

AbstractWhile scholarship suggests that improving tenure security and housing significantly reduces disaster risk at the household level within urban settings, this assertion has not been adequately tested. Tenure security can be conceived as being composed of three interrelated and overlapping forms: tenure security as determined by legal systems; de facto tenure security; and tenure security as perceived by residents. This article traces the relationship between tenure security, the quality of housing, and disaster risk on the basis of a mixed methods comparative case study of the settlements of Kawangware and Kibera in Nairobi. Although the findings suggest that owner-occupancy is associated with the structural integrity of dwellings to a greater extent than tenantship, no association was found between the length of occupancy by households and the structural integrity of the dwelling. Moreover, tenantship is not found to be closely associated with fires and flooding affecting the dwelling as extant scholarship would suggest. Formal ownership is linked with greater investment and upgrading of property with significant implications for disaster risk. Our findings highlight the complex relationship between tenure security and disaster risk in urban informal settlements and provide impetus for further investigation.

AN EXPLORATION OF THE RELATIONSHIP BETWEEN THE QUALITY OF PUBLIC GOVERNANCE AND INCOME INEQUALITY: A CASE STUDY OF VIETNAM

2021 ◽  
pp. 1-15
Author(s):  
PHUC VAN PHAN
Keyword(s):  
Income Inequality ◽  
Local Governance ◽  
Low Cost ◽  
Generalized Method Of Moments ◽  
Dynamic Panel Data ◽  
Living Standard ◽  
Public Governance ◽  
The Relationship

Public governance and income inequality relationship is complex and debatable. This paper examines the extent to which the quality of local governance affects inequality in Vietnam spanning the 2006–2016 period. I apply a generalized method of moments (GMM) estimators to a dynamic panel data extracted from the Vietnam’s provincial competitiveness index and the Vietnam household living standard surveys. The findings are that there is a positive inequality — corruption link but no statistically significant correlation coefficient between the overall level of governance and income disparity. The study, therefore, suggests that the Vietnamese Government at all levels should consider both more effective legal practices and economic low-cost solutions to mitigate corruption.

The model of HRM-trust-commitment relationships

2015 ◽  
Vol 115 (8) ◽  
pp. 1457-1480 ◽  
Author(s):  
Dagmara Lewicka ◽  
Katarzyna Krot
Keyword(s):  
Structural Equation ◽  
Affective Commitment ◽  
Content Type ◽  
Calculative Commitment ◽  
Starting Point ◽  
Research Findings ◽  
Organisational Trust ◽  
The Impact ◽  
The Relationship

Purpose – It is worth focusing on the examination of factors influencing the quality of the work environment. The purpose of this paper is to verify the influence of the HRM system and organisational trust on employee commitment. Design/methodology/approach – The survey was conducted in Poland among 370 employees in organisations from two sectors of the economy: services and industry. The verification of the theoretical model was performed based on structural equation modelling. Findings – Research findings made it possible to successfully verify the model of the relationship between the HRM system (practices, process), organisational trust and commitment. The starting point for trust in an organisation followed by commitment is the HRM system. It seems that the impact of the HRM process on creating organisational trust is higher. Research findings have also confirmed a relationship between each type of organisational trust and calculative commitment based on benefits, which is a strong determinant of affective commitment. Organisational trust is, therefore, an intermediary factor because the organisation must build trust in employees first before they become affectively committed. Originality/value – Current studies have not examined the issue of a mutual relationship between three constructs: perceived HRM practices and process, organisational trust and commitment. What is more, previous research was confined to the constructs analysed holistically without considering their complexity (different types of trust and commitment). In addition, the authors attempted to enrich Allen and Mayer’s (1991) model with a new aspect of the commitment – calculative, which is linked to the benefits received by employees. The authors also identified the mediating influence of the trust and calculative commitment onto the affective commitment.

scholarly journals PRM115 Modelling the Relationship Between Disease Severity and Utility in Multiple Sclerosis

2012 ◽  
Vol 15 (7) ◽  
pp. A481
Author(s):  
E. Fogarty ◽  
C. Walsh ◽  
S. Grehan ◽  
S. Schmitz ◽  
C. McGuigan ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Disease Severity ◽  
The Relationship

scholarly journals Manajemen Mutu Input Kelompok Bimbingan Ibadah Haji Indonesia

2017 ◽  
Vol 11 (2) ◽  
pp. 277-292
Author(s):  
Aep Kusnawan ◽  
Arif Rahman ◽  
Dede Lukman ◽  
Encep Dulwahab
Keyword(s):  
Quality Assurance ◽  
Quality Management ◽  
Qualitative Approach ◽  
One Dimension ◽  
Management Standard ◽  
Quality Assurance Process ◽  
Starting Point ◽  
Assurance Process

Hajj guidance group (KBIH) in Indonesia, still limited to quantity and have been not yet met the quality. One indication of the lack of quality of the KBIH is the quality management of inputs, namely the applied inputs and inputs of expectation. With good input and good, it can produce an out put that as expected. This study aims to determine the quality management of pilgrimage inputs by KBIH in Indonesia, represented by three regions, West Java, DKI Jakarta and South Sumatra. The method used in this research is case study with qualitative approach. This study shows that quality management for one dimension of input, especially in KBIH has not met the quality management standard. Implementation and embodiment is still limited to ideas, wishful thinking, and not conceptualized well. The results of this study have an impact on how the quality management of KBIH input in Indonesia should be implemented, so that with good input in KBIH, KBIH can improve the quality of Hajj in Indonesia. Input is a starting point in a quality assurance process, not to be ignored, underestimated, and considered not one of the important parts of quality management of its existence.Kelompok Bimbingan Ibadah Haji (KBIH) yang banyak berdiri di Indonesia, masih sebatas kuantitas belum memenuhi kualitas. Salah satu indikasi melihat kurangnya kualitas KBIH ialah pada manajemen mutu input, yaitu input terapan maupun input harapan. Dengan input yang baik dan bagus, maka bisa menghasilkan out put yang sesuai harapan. Penelitian ini bertujuan untuk mengetahui manajemen mutu input penyelenggaraan haji oleh KBIH di Indonesia, yang diwakili tiga wilayah, Jawa Barat, DKI Jakarta dan Sumatera Selatan. Metode yang digunakan dalam penelitian ini adalah studi kasus dengan pendekatan kualitatif. Penelitian ini memperlihatkan bahwa manajemen mutu untuk satu dimensi input, khususnya di KBIH belum memenuhi standar manajemen mutu. Pelaksanaan dan perwujudannya masih sebatas ide, angan-angan, dan belum terkonsep dengan baik. Hasil penelitian ini berdampak pada bagaimana manajemen mutu input KBIH di Indonesia seharusnya diimplementasikan, sehingga dengan input yang baik dalam KBIH, KBIH bisa meningkatkan kualitas penyelenggaraan ibadah haji di Indonesia. Input merupakan starting point dalam sebuah proses jaminan mutu, jangan sampai diabaikan, disepelekan, dan dianggap bukan salah satu bagian manajemen mutu yang penting keberadaannya.

scholarly journals Where the Wild Things Are

2003 ◽  
Vol 48 (1-2) ◽  
pp. 128-141 ◽  
Author(s):  
Riitta Oittinen
Keyword(s):  
Picture Books ◽  
English Language ◽  
Picture Book ◽  
Target Language ◽  
Visual Images ◽  
Forthcoming Book ◽  
Starting Point ◽  
The Relationship ◽  
Classical Picture

Abstract Translating picture books is a many-splendored thing: it includes not only the relationship between the verbal and the visual (images and other elements) but also issues like reading aloud and child images. In the following, while mainly concentrating on the visual, I will deal with the other questions as well, as they all interact and influence each other. My starting point is translating as rewriting for target-language audiences – we always need to ask the crucial question: “For whom?” Hence, while writing children’s books is writing for children, translating children’s literature is translating for children. (See Hunt 1990:1, 60-64 and Oittinen 2000.) The reasons why I take such a special interest in translating picture books are twofold: cultural and national as well as individual. In Finland, we translate a lot: 70-80% of all the books published for children annually are translations. From the perspective of picture books, the number may be even higher (and 90% of the translations come from the English language; see Rättyä 2002:18-23). Moreover, being an artist and translator of picture books makes me especially keen on the visual as a translation scholar as well. As a case study, I have chosen Maurice Sendak’s classical picture book Where the Wild Things Are and its translations into German, Swedish and Finnish. At the background of my article is my book Translating for Children (2000) as well as my forthcoming book Kuvakirja kääntäjän kädessä on translating picture books. Due to copyright reasons, I only have picture examples from illustrations of my own.

scholarly journals Cognitive Impairment in Multiple Sclerosis

Folia Medica ◽  
2016 ◽  
Vol 58 (3) ◽  
pp. 157-163 ◽  
Author(s):  
Anastasiya G. Trenova ◽  
Georgi S. Slavov ◽  
Maria G. Manova ◽  
Jana B. Aksentieva ◽  
Lyuba D. Miteva ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Cognitive Impairment ◽  
Cognitive Disorders ◽  
Social Burden ◽  
Immune Mediated ◽  
The Social ◽  
The Central Nervous System ◽  
Axonal Transection ◽  
The Relationship

Abstract Multiple sclerosis (MS) is a socially significant immune-mediated disease, characterized by demyelination, axonal transection and oligodendropathy in the central nervous system. Inflammatory demyelination and neurodegeneration lead to brain atrophy and cognitive deficit in up to 75% of the patients. Cognitive dysfunctions impact significantly patients’ quality of life, independently from the course and phase of the disease. The relationship between pathological brain findings and cognitive impairment is a subject of intensive research. Summarizing recent data about prevalence, clinical specificity and treatment of cognitive disorders in MS, this review aims to motivate the necessity of early diagnosis and complex therapeutic approach to these disturbances in order to reduce the social burden of the disease.

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