scholarly journals A Novel Active Rehabilitation Model for Stroke Patients Using Electroencephalography Signals and Deep Learning Technology

2021 ◽  
Vol 15 ◽  
Author(s):  
Ming Gao ◽  
Jie Mao

The main clinical manifestations of stroke are motor, language, sensory, and mental disorders. After treatment, in addition to being conscious, other symptoms will still remain in varying degrees. This is the sequelae of stroke, including numbness, facial paralysis, central paralysis, and central paralysis. If the sequelae of stroke are not treated effectively, they can easily develop into permanent sequelae. Most of the affected people have sequelae, and most of them have symptoms of upper limb paralysis. Therefore, it is of great significance to study how to carry out effective rehabilitation training for stroke patients to reduce the disease and even restore their motor function. Based on this background, this research aims to use deep learning technology to design a stroke rehabilitation model based on electroencephalography (EEG) signals. First, the patient’s EEG signal will be preprocessed. Then, an improved deep neural network model (IDNN) is used to get the EEG classification results. The traditional DNN model construction process is simple and suitable for scenarios where there is no special requirement for the data format, but the generalization of a single DNN model is usually poor. Large margin support vector machine (LM_SVM) is an extension method of support vector machine (SVM), suitable for any occasion. By optimizing the edge distribution, better generalization performance can be obtained. Taking into account the advantages of DNN and LM_SVM and the high aliasing characteristics of stroke data, an improved DNN model is proposed. Finally, based on the EEG recognition result of the model, the rehabilitation equipment is controlled to assist the patient in rehabilitation treatment. The experimental results verify the superiority of the EEG classification model used, and further prove that this research has good practical value.

2019 ◽  
Vol 40 (1) ◽  
pp. 91-100 ◽  
Author(s):  
Toyohiro Hamaguchi ◽  
Takeshi Saito ◽  
Makoto Suzuki ◽  
Toshiyuki Ishioka ◽  
Yamato Tomisawa ◽  
...  

Abstract Purpose Traditionally, clinical evaluation of motor paralysis following stroke has been of value to physicians and therapists because it allows for immediate pathophysiological assessment without the need for specialized tools. However, current clinical methods do not provide objective quantification of movement; therefore, they are of limited use to physicians and therapists when assessing responses to rehabilitation. The present study aimed to create a support vector machine (SVM)-based classifier to analyze and validate finger kinematics using the leap motion controller. Results were compared with those of 24 stroke patients assessed by therapists. Methods A non-linear SVM was used to classify data according to the Brunnstrom recovery stages of finger movements by focusing on peak angle and peak velocity patterns during finger flexion and extension. One thousand bootstrap data values were generated by randomly drawing a series of sample data from the actual normalized kinematics-related data. Bootstrap data values were randomly classified into training (940) and testing (60) datasets. After establishing an SVM classification model by training with the normalized kinematics-related parameters of peak angle and peak velocity, the testing dataset was assigned to predict classification of paralytic movements. Results High separation accuracy was obtained (mean 0.863; 95% confidence interval 0.857–0.869; p = 0.006). Conclusion This study highlights the ability of artificial intelligence to assist physicians and therapists evaluating hand movement recovery of stroke patients.


Author(s):  
Mohamed Abdelmoneim Elshafey ◽  
Tarek Elsaid Ghoniemy

Among the cancer diseases, breast cancer is considered one of the most prevalent threats requiring early detection for a higher recovery rate. Meanwhile, the manual evaluation of malignant tissue regions in histopathology images is a critical and challenging task. Nowadays, deep learning becomes a leading technology for automatic tumor feature extraction and classification as malignant or benign. This paper presents a proposed hybrid deep learning-based approach, for reliable breast cancer detection, in three consecutive stages: 1) fine-tuning the pre-trained Xception-based classification model, 2) merging the extracted features with the predictions of a two-layer stacked LSTM-based regression model, and finally, 3) applying the support vector machine, in the classification phase, to the merged features. For the three stages of the proposed approach, training and testing phases are performed on the BreakHis dataset with nine adopted different augmentation techniques to ensure generalization of the proposed approach. A comprehensive performance evaluation of the proposed approach, with diverse metrics, shows that employing the LSTM-based regression model improves accuracy and precision metrics of the fine-tuned Xception-based model by 10.65% and 11.6%, respectively. Additionally, as a classifier, implementing the support vector machine further boosts the model by 3.43% and 5.22% for both metrics, respectively. Experimental results exploit the efficiency of the proposed approach with outstanding reliability in comparison with the recent state-of-the-art approaches.


2020 ◽  
Vol 15 ◽  
Author(s):  
Chun Qiu ◽  
Sai Li ◽  
Shenghui Yang ◽  
Lin Wang ◽  
Aihui Zeng ◽  
...  

Aim: To search the genes related to the mechanisms of the occurrence of glioma and to try to build a prediction model for glioblastomas. Background: The morbidity and mortality of glioblastomas are very high, which seriously endangers human health. At present, the goals of many investigations on gliomas are mainly to understand the cause and mechanism of these tumors at the molecular level and to explore clinical diagnosis and treatment methods. However, there is no effective early diagnosis method for this disease, and there are no effective prevention, diagnosis or treatment measures. Methods: First, the gene expression profiles derived from GEO were downloaded. Then, differentially expressed genes (DEGs) in the disease samples and the control samples were identified. After that, GO and KEGG enrichment analyses of DEGs were performed by DAVID. Furthermore, the correlation-based feature subset (CFS) method was applied to the selection of key DEGs. In addition, the classification model between the glioblastoma samples and the controls was built by an Support Vector Machine (SVM) based on selected key genes. Results and Discussion: Thirty-six DEGs, including 17 upregulated and 19 downregulated genes, were selected as the feature genes to build the classification model between the glioma samples and the control samples by the CFS method. The accuracy of the classification model by using a 10-fold cross-validation test and independent set test was 76.25% and 70.3%, respectively. In addition, PPP2R2B and CYBB can also be found in the top 5 hub genes screened by the protein– protein interaction (PPI) network. Conclusions: This study indicated that the CFS method is a useful tool to identify key genes in glioblastomas. In addition, we also predicted that genes such as PPP2R2B and CYBB might be potential biomarkers for the diagnosis of glioblastomas.


Molecules ◽  
2012 ◽  
Vol 17 (4) ◽  
pp. 4560-4582 ◽  
Author(s):  
Khac-Minh Thai ◽  
Thuy-Quyen Nguyen ◽  
Trieu-Du Ngo ◽  
Thanh-Dao Tran ◽  
Thi-Ngoc-Phuong Huynh

2021 ◽  
Vol 16 ◽  
Author(s):  
Farida Alaaeldin Mostafa ◽  
Yasmine Mohamed Afify ◽  
Rasha Mohamed Ismail ◽  
Nagwa Lotfy Badr

Background: Protein sequence analysis helps in the prediction of protein functions. As the number of proteins increases, it gives the bioinformaticians a challenge to analyze and study the similarity between them. Most of the existing protein analysis methods use Support Vector Machine. Deep learning did not receive much attention regarding protein analysis as it is noted that little work focused on studying the protein diseases classification. Objective: The contribution of this paper is to present a deep learning approach that classifies protein diseases based on protein descriptors. Methods: Different protein descriptors are used and decomposed into modified feature descriptors. Uniquely, we introduce using Convolutional Neural Network model to learn and classify protein diseases. The modified feature descriptors are fed to the Convolutional Neural Network model on a dataset of 1563 protein sequences classified into 3 different disease classes: Aids, Tumor suppressor, and Proto oncogene. Results: The usage of the modified feature descriptors shows a significant increase in the performance of the Convolutional Neural Network model over Support Vector Machine using different kernel functions. One modified feature descriptor improved by 19.8%, 27.9%, 17.6%, 21.5%, 17.3%, and 22% for evaluation metrics: Area Under the Curve, Matthews Correlation Coefficient, Accuracy, F1-score, Recall, and Precision, respectively. Conclusion: Results show that the prediction of the proposed modified feature descriptors significantly surpasses that of Support Vector Machine model.


2020 ◽  
Vol 5 (2) ◽  
pp. 212
Author(s):  
Hamdi Ahmad Zuhri ◽  
Nur Ulfa Maulidevi

Review ranking is useful to give users a better experience. Review ranking studies commonly use upvote value, which does not represent urgency, and it causes problems in prediction. In contrast, manual labeling as wide as the upvote value range provides a high bias and inconsistency. The proposed solution is to use a classification approach to rank the review where the labels are ordinal urgency class. The experiment involved shallow learning models (Logistic Regression, Naïve Bayesian, Support Vector Machine, and Random Forest), and deep learning models (LSTM and CNN). In constructing a classification model, the problem is broken down into several binary classifications that predict tendencies of urgency depending on the separation of classes. The result shows that deep learning models outperform other models in classification dan ranking evaluation. In addition, the review data used tend to contain vocabulary of certain product domains, so further research is needed on data with more diverse vocabulary.


2021 ◽  
Vol 9 ◽  
Author(s):  
Ashwini K ◽  
P. M. Durai Raj Vincent ◽  
Kathiravan Srinivasan ◽  
Chuan-Yu Chang

Neonatal infants communicate with us through cries. The infant cry signals have distinct patterns depending on the purpose of the cries. Preprocessing, feature extraction, and feature selection need expert attention and take much effort in audio signals in recent days. In deep learning techniques, it automatically extracts and selects the most important features. For this, it requires an enormous amount of data for effective classification. This work mainly discriminates the neonatal cries into pain, hunger, and sleepiness. The neonatal cry auditory signals are transformed into a spectrogram image by utilizing the short-time Fourier transform (STFT) technique. The deep convolutional neural network (DCNN) technique takes the spectrogram images for input. The features are obtained from the convolutional neural network and are passed to the support vector machine (SVM) classifier. Machine learning technique classifies neonatal cries. This work combines the advantages of machine learning and deep learning techniques to get the best results even with a moderate number of data samples. The experimental result shows that CNN-based feature extraction and SVM classifier provides promising results. While comparing the SVM-based kernel techniques, namely radial basis function (RBF), linear and polynomial, it is found that SVM-RBF provides the highest accuracy of kernel-based infant cry classification system provides 88.89% accuracy.


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