scholarly journals Evaluation of Gestational Diabetes Mellitus Risk in South Indian Women Based on MTHFR (C677T) and FVL (G1691A) Mutations

2015 ◽  
Vol 3 ◽  
Author(s):  
Imran Ali Khan ◽  
Noor Ahmad Shaik ◽  
Vasundhara Kamineni ◽  
Parveen Jahan ◽  
Qurratulain Hasan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Mthfr C677t ◽  
Indian Women ◽  
South Indian ◽  
Diabetes Mellitus Risk

scholarly journals Peri-conceptional diet patterns and risk of gestational diabetes mellitus in South Indian women

2021 ◽  
Vol 80 (OCE5) ◽  
Author(s):  
A. Mahendra ◽  
S.H. Kehoe ◽  
S.R. Crozier ◽  
K. Kumaran ◽  
G.V. Krishnaveni ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Indian Women ◽  
Diet Patterns ◽  
South Indian

scholarly journals Prevalence and associated risk factors of gestational diabetes mellitus

2021 ◽  
Vol 10 (5) ◽  
pp. 2135
Author(s):  
Irkm Sivasarupa ◽  
Sivankumar Kumarapillai
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
South Asian ◽  
Significant Risk ◽  
Cross Sectional ◽  
Indian Women ◽  
South Indian ◽  
Associated Risk Factors

Gracelyn et al conducted a cross-sectional hospital-based study regarding the prevalence and significant risk factors of gestational diabetes mellitus in South Indian women.1 This study is important at this time because of the high frequency of gestational diabetes in South Asian ethnic groups especially in South Indian women.

scholarly journals Prevalence of pregnancy induced thyroid disorders, diabetes and hypertension in a tertiary care teaching hospital: an observational study

2019 ◽  
Vol 8 (8) ◽  
pp. 3201
Author(s):  
Gowthami Mummalaneni ◽  
Tamaraba Narasingarao ◽  
Krishna Kumari Myneni
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Gestational Hypertension ◽  
Tertiary Care ◽  
Thyroid Disorders ◽  
Gestational Period ◽  
South Indian ◽  
Wide Range ◽  
Study Population

Background: Pregnancy induced thyroid disorders, gestational diabetes mellitus (GDM) and gestational hypertension are common problems in women with gestational period. Published literate shows wide range of prevalence in pregnancy induced disorders in other states of India, and as of now the exact prevalence in our study population is not studied. Hence, there present study was aimed to know the prevalence of pregnancy induced disorders in pregnant women in South Indian population.Methods: A total of 120 subjects were followed-up at the time of recruitment to entire gestational period. Standard guidelines were followed for the assessment of thyroid hormone levels, glucose tolerance test (OGTT) and blood pressure values at different intervals and positions. Apart from detailed clinical history has been taken and routine basic and obstetrical investigations were done.Results: Prevalence of thyroid dysfunction (15.0%), gestational diabetes mellitus (11.7%) and gestational hypertension (9.2%) was reported in the present study population. Subclinical hypothyroidism was highest prevalence amount thyroid disorders. Gestational diabetes subjects have mean blood glucose levels of 230.68±17.48 mg/dL with OGTT test. Gestational hypertensive patients had SBP of 152.4±10.8 and DBP of 96.6±6.4; pre-hypertensive subjects had SBP of 134.2±5.48 and DBP of 6.8±4.6 respectively.Conclusions: Our study findings were slightly higher than normal prevalence’s which are reported earlier by various authors. We suggested that early screening, diagnosis and treatment are warranted for the prevention of maternal and fetal complications in Indian population. 

scholarly journals A1C in Gestational Diabetes Mellitus in Asian Indian Women

Diabetes Care ◽  
2007 ◽  
Vol 30 (7) ◽  
pp. 1865-1867 ◽  
Author(s):  
V. Balaji ◽  
B. S. Madhuri ◽  
S. Ashalatha ◽  
S. Sheela ◽  
S. S ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Asian Indian ◽  
Indian Women ◽  
Asian Indian Women

scholarly journals Association between functional genetic variants in retinoid X receptor-α/γ and gestational diabetes mellitus risk in a southern Chinese population

2021 ◽  
Author(s):  
Xiang-yuan Yu ◽  
Liping Song ◽  
Hui-ting Zheng ◽  
Shu-dan Wei ◽  
Xiao-lan Wen ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Genetic Variants ◽  
Multiple Testing ◽  
Genetic Model ◽  
Normal Glucose Tolerance ◽  
Retinoid X Receptor ◽  
Southern Chinese ◽  
Diabetes Mellitus Risk

To clarify the effect of retinoid X receptor-a/g (RXR-α/γ) genes functional genetic variants (RXR-α rs4842194 G>A, RXR-γ rs100537 A>G and rs2134095 T>C) on the risk of gestational diabetes mellitus (GDM), a case-control study with 573 GDM patients and 740 pregnant women with normal glucose tolerance was performed in Guangxi area of China. An odds ratio (OR) with its corresponding 95%CI was used to assess the strengths of the association between genetic variation and GDM. After adjustment of age and pre-BMI, the logistic regression analysis showed that the rs2134095 was significantly associated with GDM risk (CC vs. TT/TC: adjusted OR=0.71, 95%CI=0.56~0.90) in all subjects, and this result remained highly significant after Bonferroni’s correction for multiple testing (P=0.004). The stratified analysis showed that rs2134095 was significantly associated with the risk of GDM among age>30 years (adjusted OR=0.61, 95%CI=0.39~0.97), BMI>22 kg/m2 (adjusted OR=0.46, 95%CI= 0.30~0.70), SBP>120mmHg (adjusted OR=1.96, 95%CI= 1.14~3.36), HbA1c<6.5%(adjusted OR=1.41, 95%CI=1.11~1.78), TG≤1.7mmol/L(adjusted OR=2.57,95%CI=1.45~4.53), TC≤ 5.18mmol/L (adjusted OR=1.58, 95%CI=1.13~2.22), HDL-c≤1.5mmol/L(adjusted OR=1.70, 95%CI= 1.16~2.49) and LDL-c> 3.12 mmol/L(adjusted OR= 1.47, 95%CI= 1.08~2.00) subjects, under the recessive genetic model. We also found that rs2134095 interacted with age (Pinteraction=0.039), pre-BMI (Pinteraction=0.040) and TG (Pinteraction=0.025) influencing individual's genetic susceptibility to GDM. The rs2134095 T>C is significantly associated with the risk of GDM by effect of a single locus and / or complex joint gene-gene and gene-environment interactions. Larger sample-size and different population studies are required to confirm the findings.

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