scholarly journals Combatting Antibiotic Resistance Together: How Can We Enlist the Help of Industry?

Antibiotics ◽  
2018 ◽  
Vol 7 (4) ◽  
pp. 111 ◽  
Author(s):  
Suzanne Edwards ◽  
Chantal Morel ◽  
Reinhard Busse ◽  
Stephan Harbarth

The development of antibiotics needs to be supported through new financial stimuli, including help from the public sector. In exchange for public support, industry should be asked to do what is in their power to help curb the inappropriate use of antibiotics. This work discusses key areas through which industry has an important influence on antibiotic consumption and where agreements can be made alongside financial incentives, even those intended to stimulate very early research. As long as the traditional unit sale-based business model for antibiotics remains in place, profit-making incentives will likely undermine efforts to sell and utilize antibiotics in a sustainable manner. In the short-term, while we try to come to a consensus on how best to fix the market, we need measures to prevent major over-selling and inappropriate promotion—especially for new, badly needed antibiotics that reach the market. This paper explores ways in which the pharmaceutical industry could help buttress sustainable antibiotic use while we search for more long-term, constructive, mutually-beneficial ways to organize the market.

2017 ◽  
Vol 9 (1) ◽  
pp. 168
Author(s):  
Md Mostafizur Rahman ◽  
Mahmud Uz Zaman

Pharmaceuticals agglomerations consistently use their brand image and versatile product portfolios to consolidate their position in the financial sector, which is evident in their continuous profit making and expansion in market share. This paper explores the short-term and long-term investment attractiveness through ‘consumer centric decision’ approach in two selected pharmaceutical companies, Renata Limited and Orion Pharma Limited, of Bangladesh over the last three years’ period. This research adopts a systematic approach which primarily addresses the various concerns of investors to illustrate the decision-making process of the existing and future investors. Using primarily domestic transaction data, this study explores how the leading pharmaceuticals companies of Bangladesh effectively use the wide array of drug portfolios mix with appropriate branding techniques to increase their financial profit and market share simultaneously. Both SWOT analysis and Porters Five Forces Model explore the business analysis of Renata Limited in compare to Orion Pharma Limited that provides a conclusion regarding investors’ decision to invest in Renata Limited. Considering the financial analysis, Renata’s financial liquidity is not very satisfactory and could have been improved further if management is prudent on financial strategy settings. Findings of the business analysis indicate that Renata Limited would be a good investment choice for existing and prospective shareholders based on its opportunities for long term and short term growth and further expansion in developing the market. The results suggest that even lower liquidity coupled with higher interest borrowings can be balanced by posing positive picture to the public shareholders by returning the positive dividend to them.


2018 ◽  
Vol 17 (2) ◽  
pp. 783-810
Author(s):  
Angélica Pott de Medeiros ◽  
Giulia Xisto de Oliveira ◽  
Reisoli Bender Filho

Resumo: O cenário de instabilidade política, a recessão econômica e as mudanças nas regras de concessão de crédito pautaram o objetivo de examinar o relacionamento do crédito consignado, por segmento de concessão, com variáveis macroeconômicas, caso do consumo, da produção industrial e do produto agregado, na última década (2007-2017). Os resultados foram obtidos por meio da estimação do vetor de correção de erros, funções de impulso-resposta e decomposição da variância, possibilitando a análise das relações de curto e de longo prazo entre as séries temporais e indicaram que as diferentes modalidades do crédito consignado implicam efeitos distintos sobre as variáveis econômicas em curto prazo. O segmento de aposentados e pensionistas impacta positivamente ambas as variáveis analisadas, com destaque para os bens de consumo das famílias. Já a concessão ao setor privado, embora represente a menor parcela do crédito consignado concedido, mostrou elevada sensibilidade a alterações na oferta dessa modalidade de crédito, enquanto que o crédito ao setor público, de maior participação, apresentou efeitos reduzidos e de curta duração.Palavras-chave: Crédito consignado. Segmentos. Economia brasileira. Payroll loans: segments and economic effects Abstract: The environment of political instability, economic recession and changes in the rules of granting credit were guiders to aim to examine the payroll loans relationship, by concession segment, with macroeconomic variables, case of consumption, industrial production and aggregate product, in the last decade (2007-2017). The results obtained by error correction vector estimation, and functions of impulse-response and variance decomposition, making it possible to analyze the short- and long-term relationships between the time series and indicated that the different modalities of payroll loans imply different effects on economic short-term variables. With retirees and pensioners segment positively impact on both analyzed variables, highlighting the household consumption goods. The concession to the private sector, although it represents the smallest portion of payroll loans granted, it showed high sensitivity to the changes of this modality. About credit to the public sector, which has the biggest portion, it showed reduced and short-term effects.Keywords: Payroll loans. Segments. Brazilian economy.


2017 ◽  
Vol 7 (1) ◽  
pp. 1
Author(s):  
Agus Saiful Abib ◽  
Efi Yulistyowati ◽  
Amri Panahatan Sihotang

<p>Tahun 2016, pemerintah mengeluarkan kembali kebijakan <em>Tax</em> <em>Amnesty </em>yang dituangkan dalam Undang-Undang Nomor 11 Tahun 2016 tentang Pengampunan Pajak. Pengampunan Pajak (<em>Tax</em> <em>Amnesty)</em> ini diharapkan dapat meningkatkan penerimaan pajak dalam jangka pendek melalui pembayaran uang tebusan, meningkatkan penerimaan pajak dalam jangka panjang melalui perluasan basis data pemajakan, meningkatkan kepatuhan Wajib Pajak, transisi ke sistem perpajakan baru yang lebih kuat dan adil, dan mendorong rekonsiliasi perpajakan nasional. Sehubungan dengan hal tersebut, untuk mengetahui apakah program <em>Tax</em> <em>Amnesty</em> Indonesia Tahun 2016 berhasil atau tidak, khususnya dalam meningkatkan kepatuhan wajib pajak, maka perlu dilakukan penelitian tentang : “Implikasi Penerapan Undang-Undang Nomor 11 Tahun 2016 tentang Pengampunan Pajak (<em>Tax</em> <em>Amnesty</em>) dalam Meningkatkan Kepatuhan Wajib Pajak”. Adapun permasalahan yang akan dibahas adalah bagaimana implikasi penerapan Undang-Undang Nomor 11 Tahun 2016 tentang Pengampunan Pajak<em> (Tax</em> <em>Amnesty)</em> dalam meningkatkan kepatuhan Wajib Pajak ? Berdasarkan implikasi tersebut, maka bagaimana sebaiknya pengaturan perpajakan yang akan datang ? Berdasarkan permasalahan tersebut jenis penelitian ini adalah yuridis normatif yang akan dikaji dengan pendekatan perundang-undangan, spesifikasi penelitiannya diskriptif analitis, data yang dipergunakan data sekunder, yang dianalisis secara kualitatif. Hasil penelitian menunjukkan bahwa implikasi penerapan Undang-Undang Nomor 11 Tahun 2016 tentang Pengampunan Pajak<em> (Tax</em> <em>Amnesty)</em> dapat meningkatkan kepatuhan Wajib Pajak, dan berdasarkan implikasi tersebut SE Dirjen Pajak No. SE - 06/PJ/2017 seharusnya tidak hanya untuk tahun pajak 2017 saja, tetapi juga untuk tahun-tahun yang akan datang. Di samping itu perlu ada peraturan yang mengatur tentang pengawasan terhadap pelaksanaan hak Wajib Pajak.</p><pre>In 2016, the government re-issue the Tax Amnesty policy as outlined in Law Number 11 Year 2016 on Tax Amnesty. The Tax Amnesty is expected to increase tax revenue in the short term through ransom payments, increase tax revenues over the long term through the expansion of taxation databases, increase taxpayer compliance, transition to a stronger and more just tax system, and encourage national tax reconciliation. In relation to this matter, to find out whether the program of Tax Amnesty Indonesia Year 2016 succeed or not, especially in increasing taxpayer compliance, it is necessary to do research on: "Implications Implementation of Law Number 11 Year 2016 on Tax Amnesty in Improving Taxpayer Compliance ". The problem to be discussed is how the implications of the implementation of Law Number 11 Year 2016 on Tax Amendment (Tax Amnesty) in improving taxpayer compliance? Based on these implications, then how should the taxation arrangements to come? Based on the problem, this type of research is normative juridical which will be studied with the approach of legislation, the analytical descriptive research specification, the data used secondary data, which analyzed qualitatively. The result of the research shows that the implication of the implementation of Law Number 11 Year 2016 on Tax Amnesty can improve Taxpayer compliance, and based on the implication of SE Dirjen Pajak No. SE - 06 / PJ / 2017 should not only be for the fiscal year 2017 alone, but also for the years to come. In addition, there should be a regulation that regulates the supervision of the implementation of taxpayers' rights.</pre>


2021 ◽  
Vol 4 (2) ◽  
Author(s):  
Sanchayan Banerjee ◽  
Manu Savani ◽  
Ganga Shreedhar

This article reviews the literature on public support for ‘soft’ versus ‘hard’ policy instruments for behaviour change, and the factors that drive such preferences. Soft policies typically include ‘moral suasion’ and educational campaigns, and more recently behavioural public policy approaches like nudges. Hard policy instruments, such as laws and taxes, restrict choices and alter financial incentives. In contrast to the public support evidenced for hard policy instruments during COVID-19, prior academic literature pointed to support for softer policy instruments. We investigate and synthesise the evidence on when people prefer one type of policy instrument over another. Drawing on multi-disciplinary evidence, we identify perceived effectiveness, trust, personal experience and self-interest as important determinants of policy instrument preferences, along with broader factors including the choice and country context. We further identify various gaps in our understanding that informs and organise a future research agenda around three themes. Specifically, we propose new directions for research on what drives public support for hard versus soft behavioural public policies, highlighting the value of investigating the role of individual versus contextual factors (especially the role of behavioural biases); how preferences evolve over time; and whether and how preferences spillovers across different policy domains.


2018 ◽  
Author(s):  
Robinson Hordoir ◽  
Lars Axell ◽  
Anders Höglund ◽  
Christian Dieterich ◽  
Filippa Fransner ◽  
...  

Abstract. We present Nemo-Nordic, a Baltic &amp; North Sea model based on the NEMO ocean engine. Surrounded by highly industrialised countries, the Baltic and North seas, and their assets associated with shipping, fishing and tourism; are vulnerable to anthropogenic pressure and climate change. Ocean models providing reliable forecasts, and enabling climatic studies, are important tools for the shipping infrastructure and to get a better understanding of effects of climate change on the marine ecosystems. Nemo-Nordic is intended to come as a tool for both short term and long term simulations, and to be used for ocean forecasting as well as process and climatic studies. Here, the scientific and technical choices within Nemo-Nordic are introduced, and the reasons behind the design of the model and its domain, and the inclusions of the two seas, are explained. The model's ability to represent barotropic and baroclinic dynamics, as well as the vertical structure of the water column, is presented. Biases are shown and discussed. The short term capabilities of the model are presented, and especially its capabilities to represent sea level on an hourly timescale with a high degree of accuracy. We also show that the model can represent longer time scale, with a focus on the Major Baltic Inflows and the variability of deep water salinity in the Baltic Sea.


2019 ◽  
Vol 374 (1788) ◽  
pp. 20190220 ◽  
Author(s):  
Ana S. L. Rodrigues ◽  
Sophie Monsarrat ◽  
Anne Charpentier ◽  
Thomas M. Brooks ◽  
Michael Hoffmann ◽  
...  

Ecological baselines—reference states of species' distributions and abundances—are key to the scientific arguments underpinning many conservation and management interventions, as well as to the public support to such interventions. Yet societal as well as scientific perceptions of these baselines are often based on ecosystems that have been deeply transformed by human actions. Despite increased awareness about the pervasiveness and implications of this shifting baseline syndrome, ongoing global assessments of the state of biodiversity do not take into account the long-term, cumulative, anthropogenic impacts on biodiversity. Here, we propose a new framework for documenting such impacts, by classifying populations according to the extent to which they deviate from a baseline in the absence of human actions. We apply this framework to the bowhead whale ( Balaena mysticetus ) to illustrate how it can be used to assess populations with different geographies and timelines of known or suspected impacts. Through other examples, we discuss how the framework can be applied to populations for which there is a wide diversity of existing knowledge, by making the best use of the available ecological, historical and archaeological data. Combined across multiple populations, this framework provides a standard for assessing cumulative anthropogenic impacts on biodiversity. This article is part of a discussion meeting issue ‘The past is a foreign country: how much can the fossil record actually inform conservation?’


2019 ◽  
Vol 75 (1) ◽  
pp. 14-29 ◽  
Author(s):  
Jane Mingjie Lim ◽  
Shweta Rajkumar Singh ◽  
Minh Cam Duong ◽  
Helena Legido-Quigley ◽  
Li Yang Hsu ◽  
...  

Abstract Background Global recognition of antimicrobial resistance (AMR) as an urgent public health problem has galvanized national and international efforts. Chief among these are interventions to curb the overuse and misuse of antibiotics. However, the impact of these initiatives is not fully understood, making it difficult to assess the expected effectiveness and sustainability of further policy interventions. We conducted a systematic review to summarize existing evidence for the impact of nationally enforced interventions to reduce inappropriate antibiotic use in humans. Methods We searched seven databases and examined reference lists of retrieved articles. To be included, articles had to evaluate the impact of national responsible use initiatives. We excluded studies that only described policy implementations. Results We identified 34 articles detailing interventions in 21 high- and upper-middle-income countries. Interventions addressing inappropriate antibiotic access included antibiotic committees, clinical guidelines and prescribing restrictions. There was consistent evidence that these were effective at reducing antibiotic consumption and prescription. Interventions targeting inappropriate antibiotic demand consisted of education campaigns for healthcare professionals and the general public. Evidence for this was mixed, with several studies showing no impact on overall antibiotic consumption. Conclusions National-level interventions to reduce inappropriate access to antibiotics can be effective. However, evidence is limited to high- and upper-middle-income countries, and more evidence is needed on the long-term sustained impact of interventions. There should also be a simultaneous push towards standardized outcome measures to enable comparisons of interventions in different settings.


2016 ◽  
Vol 8 (3) ◽  
pp. 55 ◽  
Author(s):  
Lionel Effiom ◽  
Peter Ubi

<p>It is common knowledge that Nigeria’s road infrastructure, and indeed the general infrastructure of sub-Saharan Africa, is in a most despicable condition. This paper formalises this observation by providing current data to support the hypothesis. By deploying descriptive and theoretical methodological approaches, it demonstrates that road infrastructure is not only deteriorating but also suffers from a twin evil of deficit and deprioritisation in the public sector’s preferential scale–a state of indifference of sorts. Long and short term policy choices have to be made to urgently address the issue. In the short term, infrastructure concessions, public private partnerships (PPP), pension funds, sovereign wealth fund, savings from reduction in fuel subsidies, leveraging on the Africa Growth and Opportunity Act (AGOA) mechanism–are part of the portfolio of choices that government can readily choose from. In the long term however, the paper recommends increase in the statutory allocation to the states and local governments which would ensure that component units of the federation control more resources to deploy and develop infrastructure in their immediate domain.</p>


Author(s):  
Thomas R. Hughes ◽  
Frank D. Davidson

Even though conflict is increasingly finding its way into school settings, there is evidence that school leaders do not view themselves as being adequately equipped to meet the growing challenges. Training on short-term approaches to dealing with immediate issues may be available to practitioners through professional development offerings, but there is more involved in successfully and sustainably dealing with conflict than getting through a tense moment. School leaders need to be able to understand the causes and complexities—as well as navigate time elements—associated with ongoing conflict that can take place at the personal as well as organizational levels. Beyond understanding these concepts, administrators themselves need to increase the capacity of their staff and their organizations to assist in their development. In addition to learning how to recognize patterns and underlying causes advancing adversity, administrators would do well to invest in long-term conflict diminishing approaches such as building trust and improving interpersonal and organizational capacity as ways to increase credibility within and outside of the school itself. Finding people who can think critically and work adaptively to solve problems could prove to be a real advantage for educational leaders who strive to reduce the stress of the workplace and create a more collegial climate within the schools they serve. Building trust and the ability to “come through” capably for others even in tough situations increases the credibility of leaders. Leading through conflict with this credibility in turn helps to sustain a positive climate in schools.


2020 ◽  
Vol 12 (3) ◽  
pp. 1230
Author(s):  
Fabricio Casarejos

The main objective of this work is to foster long-term and regenerative perspectives on global sustainability. In pursuing this goal, this study encompasses a critical analysis and synthesis of insights from the fields of systems and resilience thinking, a conceptual framework for modeling and envisioning socio-ecological systems, and the proposition of the “flourishing within boundaries” archetype, which is conceived to provide meaningful insights regarding the essential conditions that would enable global society to flourish not just safely but also fairly. Through systems dynamics modeling, portrayed scenarios emphasize that the higher the regenerative societal change achieved, the greater the exponential behavior of the system’s speed towards promising socio-ecological outcomes. Especially for longer time horizons, the overall results reveal that the pace of the transitions associated with the societal action is inherently higher than those associated with the limiting social and ecological factors. Actions taken by individuals in the local realm and short-term time horizon may not only have immediate local effects but also a variety of innumerous ones that radiate out for years, decades, and even centuries to come. Finally, the pursuit of flourishing within boundaries relies on thinking rationally, globally, and above all, through a long-term and regenerative perspective.


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