Prevalence and Predictors of Osteoporosis Among the Chinese Population in Klang Valley, Malaysia

The prevalence of osteoporosis is forecasted to escalate in Malaysia with an increasing elderly population. This study aimed to analyze the prevalence and the risk factors of osteoporosis among middle-aged and elderly Chinese Malaysians. Three hundred sixty seven Malaysian Chinese aged ≥40 years in Klang Valley, Malaysia, were recruited. All subjects completed a structured questionnaire comprised of demographic details, medical history, diet, and lifestyle practices. Body anthropometry and bone mineral density measurements were also performed. The relationship between bone health status and risk factors was determined using multivariate logistic regression. Fifteen-point-three percent of the overall study population and 32.6% of those aged ≥71 years had osteoporosis. The prevalence of osteoporosis among women (18.9%) was higher than men (11.5%). The significant predictors of osteoporosis were age, body weight, and low monthly income. Lean mass, low education level, and being underweight predicted osteoporosis in women. Lean mass was the only significant predictor of osteoporosis in men. Overall, 15.3% of the Malaysian Chinese aged ≥40 years from Klang Valley, Malaysia, had osteoporosis. Osteoporosis was associated positively with increased age and low monthly income and negatively with body weight. Therefore, osteoporosis preventive strategies targeting Chinese elderly from a low socioeconomic background is necessary.

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Development of Osteoporosis Screening Algorithm for Population Aged 50 Years and above in Klang Valley, Malaysia

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph17072526 ◽

2020 ◽

Vol 17 (7) ◽

pp. 2526 ◽

Cited By ~ 1

Author(s):

Shaanthana Subramaniam ◽

Chin-Yi Chan ◽

Ima-Nirwana Soelaiman ◽

Norazlina Mohamed ◽

Norliza Muhammad ◽

...

Keyword(s):

Risk Factors ◽

Body Weight ◽

Low Income ◽

Operating Characteristics ◽

Osteoporosis Screening ◽

Malaysian Population ◽

Reduced Body ◽

Income Status ◽

Screening Algorithm ◽

Klang Valley

Background: The current osteoporosis screening instruments are not optimized to be used among the Malaysian population. This study aimed to develop an osteoporosis screening algorithm based on risk factors for Malaysians. Methods: Malaysians aged ≥50 years (n = 607) from Klang Valley, Malaysia were interviewed and their bone health status was assessed using a dual-energy X-ray absorptiometry device. The algorithm was constructed based on osteoporosis risk factors using multivariate logistic regression and its performance was assessed using receiver operating characteristics analysis. Results: Increased age, reduced body weight and being less physically active significantly predicted osteoporosis in men, while in women, increased age, lower body weight and low-income status significantly predicted osteoporosis. These factors were included in the final algorithm and the optimal cut-offs to identify subjects with osteoporosis was 0.00120 for men [sensitivity 73.3% (95% confidence interval (CI) = 54.1%–87.7%), specificity 67.8% (95% CI = 62.7%–85.5%), area under curve (AUC) 0.705 (95% CI = 0.608–0.803), p < 0.001] and 0.161 for women [sensitivity 75.4% (95% CI = 61.9%–73.3%), specificity 74.5% (95% CI = 68.5%–79.8%), AUC 0.749 (95% CI = 0.679–0.820), p < 0.001]. Conclusion: The new algorithm performed satisfactorily in identifying the risk of osteoporosis among the Malaysian population ≥50 years. Further validation studies are required before applying this algorithm for screening of osteoporosis in public.

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Abstract P111: A Cluster Randomized Controlled Trial to Examine the Effects of Tai Chi and Walking Exercises on Weight Loss, Metabolic Syndrome Parameters, and Bone Mineral Density

Circulation ◽

10.1161/circ.131.suppl_1.p111 ◽

2015 ◽

Vol 131 (suppl_1) ◽

Author(s):

Yao Jie Xie ◽

Stanley Sai-chuen Hui ◽

Timothy Chi-yui Kwok ◽

Jean Woo

Keyword(s):

Bone Mineral Density ◽

Blood Pressure ◽

Metabolic Syndrome ◽

Weight Loss ◽

Body Weight ◽

Waist Circumference ◽

Lean Mass ◽

Tai Chi ◽

Density Lipoprotein ◽

Mineral Density

Introduction: Tai Chi and walking are both moderate-intensity physical activity (PA) that can be easily practiced in daily life. The purpose of this study was to better understand that after practicing these two types of PAs in a relative short term and keeping the stable dietary intake in this period, how much body weight would be reduced and what extent the metabolic syndrome parameters would be improved; and if a significant weight loss was observed, whether this exercise-induced weight loss had adverse effect on bone mineral density (BMD). Methods: Three-hundred seventy-four healthy and physically inactive adults (45.8±5.3 years) from 9 geographic areas in Hong Kong were randomized to 12 weeks training (45 minutes per day, 5 days per week) of Tai Chi (n=124) or self-paced walking (n=121), or control group (n=129) at area level. Body weight, fat and lean mass, waist circumference, blood pressure and regional BMD, as well as the fasting blood samples were obtained at the beginning and end of trial. Fasting blood glucose (FBG), total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and triglycerides were analyzed. Results: On average, Tai Chi and walking groups lost 0.50 and 0.76 kg of body weight, 0.47 and 0.59 kg of fat mass, respectively (all p<0.001). No significant changes were observed for lean mass and BMD. Two intervention groups had significant improvements in waist circumference and FBG. The between-group difference of waist circumference and FBG was -3.7 cm and -0.18 mmol/L for Tai Chi vs. control; and -4.1 cm and -0.22 mmol/L for walking vs. control (all p<0.001). No significant differences were observed regarding blood pressure, total cholesterol, HDL-C, LDL-C and triglycerides compared to control (all p>0.05). The effects on all outcomes between Tai Chi and walking were similar (all p>0.05). Among intervention groups, change in lean mass, not fat mass or total weight loss, was significantly correlated to the change in BMD. Conclusions: 12-week Tai Chi and walking exercises can produce moderate weight loss and improve the waist circumference and FBG in middle-aged Hong Kong Chinese people, with no additional effects on BMD.

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Prevalence of osteoporosis in patients with severe peripheral artery disease

Orvosi Hetilap ◽

10.1556/oh.2013.29532 ◽

2013 ◽

Vol 154 (10) ◽

pp. 369-375 ◽

Cited By ~ 2

Author(s):

Mátyás Fehérvári ◽

Miklós Krepuska ◽

Csaba Csobay-Novák ◽

Péter Lakatos ◽

Zoltán Oláh ◽

...

Keyword(s):

Risk Factors ◽

Bone Mineral Density ◽

Bone Mineral ◽

Limb Ischemia ◽

Cross Sectional Study ◽

Serum Markers ◽

Mineral Density ◽

Cross Sectional ◽

Severe Atherosclerosis ◽

Prevalence Of Osteoporosis

Introduction: Recent studies highlighted a significant association between bone mineral density and atherosclerosis. Cardiovascular disease is the main cause of death in Western countries, while the prevalence of osteoporosis reached 9% in Hungary. Aim: The aim of this study was to investigate the prevalence of osteoporosis among patients with peripheral vascular disease. Methods: In a cross-sectional study bone mineral density using dual-energy X-ray absorptiometry in 172 patients with lower limb ischemia was investigated. According to previous medical history and blood tests, risk factors of atherosclerosis were also assessed and serum markers of bone turnover and other factors that could influence osteoporosis were evaluated. Results: Prior to bone mineral density screening, osteoporosis was known in 9% of patients. Based on osteodensitometric evaluation, 37% of the patients were diagnosed as having osteopenia and 31% as having osteoporosis. According to risk factors, different patient groups were created. Significantly more female than male patients had osteoporosis, while smoking, age and body mass index failed to affect the prevalence of osteoporosis. Conclusion: These results suggest that patients with severe atherosclerosis need to be regularly screened and, if necessary, treated for osteoporosis. Orv. Hetil., 2013, 154, 369–375.

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Prevalence and Risk Factors of Osteoporosis in Women Referring to the Bone Densitometry Academic Center in Urmia, Iran

Global Journal of Health Science ◽

10.5539/gjhs.v8n7p135 ◽

2015 ◽

Vol 8 (7) ◽

pp. 135 ◽

Cited By ~ 4

Author(s):

Marzieh Saei Ghare Naz ◽

Giti Ozgoli ◽

Mir Amir Aghdashi ◽

Fatemeh Salmani

Keyword(s):

Risk Factors ◽

Bone Mineral Density ◽

Bone Mineral ◽

Bone Fracture ◽

Significant Risk ◽

The Body ◽

Mineral Density ◽

Total Prevalence ◽

History Of ◽

Prevalence Of Osteoporosis

BACKGROUND: Osteoporosis is one of the fastest growing health problems around the world. Several factors can affect this silent disease. The current study aimed to determine the prevalence and risk factors of osteoporosis in women in Urmia, a city in northwestern Iran.METHODS: This cross‑sectional study was performed on 360 non-pregnant women over the age of 15 who referred for bone density testing to the Urmia Imam Khomeini Academic Hospital. Data were collected by questionnaire, and bone mineral density of the femoral neck and lumbar spines L1- L4 was evaluated by dual X-ray absorptiometry.RESULTS: The total prevalence of osteoporosis in this study was 42.2%; prevalence of osteoporosis among women 45 years old or less was 14.3% and over the age of 45 years was 50.7%. The factors such as level of education, history of bone fracture, disease history (rheumatoid arthritis, diabetes, high blood pressure), gravidity and parity values, duration of lactation (p<0.001), nutrition dimension of lifestyle (p=0.03), and green tea consumption (p=002) showed a statistically significant association with the bone mineral density. According to the regression model, age (OR=1.081), history of bone fracture (OR=2.75), and gravidity (OR=1.14) were identified as significant risk factors for osteoporosis, while the body mass index (OR=0.94) was identified as a protector against osteoporosis.CONCLUSION: The prevalence of osteoporosis in this study was high, and findings showed that the advancement of age, lifestyle, and reproductive factors (especially gravidity and duration of lactation) were determining factors for osteoporosis .Appropriate educational programs and interventions could help to increase the women’s peak bone mass therefore reducing their risk of developing osteoporosis.

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Signalment differences in bone mineral content and bone mineral density in canine appendicular bones

Veterinary and Comparative Orthopaedics and Traumatology ◽

10.3415/vcot-07-01-0009 ◽

2008 ◽

Vol 21 (02) ◽

pp. 147-151 ◽

Cited By ~ 9

Author(s):

S. Loebcke ◽

M. Skalicky ◽

S. Grampp ◽

D. Lorinson ◽

K. Lorinson

Keyword(s):

Risk Factors ◽

Bone Mineral Density ◽

Body Weight ◽

Bone Mineral Content ◽

Bone Mineral ◽

Mineral Content ◽

Regions Of Interest ◽

Middle Aged ◽

Mineral Density ◽

Fracture Development

SummaryThe objective was to determine signalment-related differences in bone mineral content (BMC) and bone mineral density (BMD) in dogs. Unilateral appendicular bones were harvested from 62 canine cadavers. Middiaphyseal regions of interest (ROIs) were scanned using a Hologic® DXA device Braincon, Vienna, Austria). BMC and BMD were calculated within this region. Middle-aged dogs (3 . 10 years) revealed the highest BMC and BMD levels. Mean BMC and BMD were higher in males compared to females. Furthermore, bodyweight of the male dogs was significantly higher compared to the females (P<0.0001). Body weight and bone length were significantly associated with BMC and BMD (P.0.023) in all bones but the radius. These data suggest that BMC and BMD appear to be highest in male large-breed dogs with a body weight greater than 30 kg. These results may help determine risk factors in fracture development and healing.

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AB0901 PREVALENCE OF OSTEOPOROSIS IN ITALIAN POSTMENOPAUSAL WOMEN ACCORDING TO DEFRA ALGORITHM

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2020-eular.3821 ◽

2020 ◽

Vol 79 (Suppl 1) ◽

pp. 1754.1-1754

Author(s):

A. M. Lurati ◽

A. Laria ◽

L. Castelnovo ◽

P. Faggioli ◽

A. Tamburello ◽

...

Keyword(s):

Risk Factors ◽

Fracture Risk ◽

Postmenopausal Women ◽

Prevention Strategies ◽

Mineral Density ◽

Common Risk Factor ◽

Previous Fracture ◽

Menopausal Women ◽

Post Menopausal ◽

Prevalence Of Osteoporosis

Background:Osteoporosis is a recognized health problem and the burden of the disease is mostly associated with the occurrence of hip and vertebral fracture.Objectives:This study was aimed at evaluating the prevalence of osteoporosis in Italian postmenopausal women, defined by DeFRA calculation as a 10 years fracture risk equal or higher than 20%.Methods:This is a monocenter cohort study evaluating 1850 post-menopausal women aged 50 years and older. All the participants were evaluated as far as anthropometrics. Defra questionnaire was administered and calculated with bone mineral density (DXA) measured at lumbar spine and femoral neck.Results:The prevalence of osteoporosis as assessed by DeFRA was 29.8% in the whole population, according to literature. The frequency of a risk fracture equal or higher than 20% varied from 7.9% in the group aged 50-59 years to 35% in subjects aged >80. Among clinical risk factors for fracture, the presence of a previous fracture (spine primarily) was the most commonly observed.Conclusion:Our data showed that about one third of post-menopausal women aged 50 and older in Italy has osteoporosis on the basis of DeFRA algorithm, with a high 10 years fracture risk. A previous fracture is the most common risk factor. The data should be considered in relation to the need to increase prevention strategies and therapeutic intervention.Disclosure of Interests:None declared

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Risk Factors for Acute Chest Syndrome in Patients From Low Socioeconomic Background

Journal of Pediatric Hematology/Oncology ◽

10.1097/mph.0b013e31821ed2f0 ◽

2011 ◽

Vol 33 (7) ◽

pp. 484-486 ◽

Cited By ~ 3

Author(s):

Jerônimo Gonçalves Araújo ◽

Carlos André Araújo-Melo ◽

Osvaldo Alves de Menezes-Neto ◽

Diego Fernandes Chagas da Silveira ◽

Jailson Barros Correia ◽

...

Keyword(s):

Risk Factors ◽

Socioeconomic Background ◽

Acute Chest Syndrome ◽

Low Socioeconomic

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Prevalence of Osteoporosis and Its Risk Factors in Men with COPD in Qazvin

International Journal of Chronic Diseases ◽

10.1155/2016/4038530 ◽

2016 ◽

Vol 2016 ◽

pp. 1-6 ◽

Cited By ~ 3

Author(s):

Mahnaz Abbasi ◽

Mohammadali Zohal ◽

Banafsheh Atapour ◽

Zohreh Yazdi

Keyword(s):

Risk Factors ◽

Bone Mineral ◽

Systemic Adverse Effect ◽

Chronic Obstructive ◽

Mineral Density ◽

Obstructive Pulmonary Disease ◽

Copd Patients ◽

Bone Mineral Densitometry ◽

Proper Diagnosis ◽

Prevalence Of Osteoporosis

Introduction. Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Proper diagnosis of osteoporosis as a systemic adverse effect of COPD is of significant importance. The present study aimed at evaluating the prevalence of osteoporosis and its risk factors in men suffering from COPD in Qazvin (2014).Methods. This descriptive-analytical study was conducted on 90 patients with COPD using random sampling. Anthropometric data and results from physical examination were collected. Pulmonary function test and bone mineral densitometry were done for all participants as well.Results.The prevalence of osteopenia and osteoporosis in COPD patients was 31.5 and 52.8 percent, respectively. Bone mineral density (BMD) at the femoral neck was associated significantly with body mass index (BMI), increased severity of COPD, and use of oral corticosteroid (P<0.05).Conclusion.The results showed that patients’ BMI and severity of COPD are two valuable risk factors for osteoporosis screening in COPD patients.

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