scholarly journals Crosstalk between Existential Phenomenological Psychotherapy and Neurological Sciences in Mood and Anxiety Disorders

Biomedicines ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 340
Author(s):  
Lehel Balogh ◽  
Masaru Tanaka ◽  
Nóra Török ◽  
László Vécsei ◽  
Shigeru Taguchi

Psychotherapy is a comprehensive biological treatment modifying complex underlying cognitive, emotional, behavioral, and regulatory responses in the brain, leading patients with mental illness to a new interpretation of the sense of self and others. Psychotherapy is an art of science integrated with psychology and/or philosophy. Neurological sciences study the neurological basis of cognition, memory, and behavior as well as the impact of neurological damage and disease on these functions, and their treatment. Both psychotherapy and neurological sciences deal with the brain; nevertheless, they continue to stay polarized. Existential phenomenological psychotherapy (EPP) has been in the forefront of meaning-centered counseling for almost a century. The phenomenological approach in psychotherapy originated in the works of Martin Heidegger, Ludwig Binswanger, Medard Boss, and Viktor Frankl, and it has been committed to accounting for the existential possibilities and limitations of one’s life. EPP provides philosophically rich interpretations and empowers counseling techniques to assist mentally suffering individuals by finding meaning and purpose to life. The approach has proven to be effective in treating mood and anxiety disorders. This narrative review article demonstrates the development of EPP, the therapeutic methodology, evidence-based accounts of its curative techniques, current understanding of mood and anxiety disorders in neurological sciences, and a possible converging path to translate and integrate meaning-centered psychotherapy and neuroscience, concluding that the EPP may potentially play a synergistic role with the currently prevailing medication-based approaches for the treatment of mood and anxiety disorders.

Author(s):  
Lehel Balogh ◽  
Masaru Tanaka ◽  
Nóra Török ◽  
László Vécsei ◽  
Shigeru Taguchi

Psychotherapy is a comprehensive biological treatment modifying complex underlying cognitive, emotional, behavioral, and regulatory responses in the brain, leading patients with mental illness to a new interpretation of the sense of self and others. Psychotherapy is an art of science integrated with psychology and/or philosophy. Neurological science studies the neurological basis of cognition, memory, and behavior as well as the impact of neurological damage and disease on the functions, and their treatment. Both psychotherapy and neurological science deal with the brain; nevertheless, they continue to stay polarized far. Existential phenomenological psychotherapy (EPP) has been in the forefront of meaning-centered counseling for almost a century. The phenomenological approach in psychotherapy originated in the works of Martin Heidegger, Ludwig Binswanger, Medard Boss and Viktor Frankl, and it has been committed to account for the existential possibilities and limitations of one’s life. EPP provides philosophically rich interpretations and empowers counseling techniques to assist mentally suffering individuals by finding meaning and purpose of life. The approach has proven to be effective in treating mood and anxiety disorders. This narrative review article demonstrates the development of EPP, the therapeutic methodology, evidence-based accounts of its curative techniques, current understanding of mood and anxiety disorders in neurological science, and a possible converging path to translate and integrate meaning-centered psychotherapy and neurological science, concluding that the existential phenomenological psychotherapy potently plays a synergistic role with the currently prevailing medication-based approaches for the treatment of mood and anxiety disorders.


Author(s):  
Lehel Balogh ◽  
Masaru Tanaka ◽  
Nóra Török ◽  
László Vécsei ◽  
Shigeru Taguchi

Psychotherapy is a comprehensive biological treatment modifying complex underlying cognitive, emotional, behavioral, and regulatory responses in the brain, leading patients with mental illness to a new interpretation of the sense of self and others. Psychotherapy is an art of science integrated with psychology and/or philosophy. Neurological science studies the neurological basis of cognition, memory, and behavior as well as the impact of neurological damage and disease on the functions, and their treatment. Both psychotherapy and neurological science deal with the brain; nevertheless, they continue to stay polarized far. Existential phenomenological psychotherapy (EPP) has been in the forefront of meaning-centered counseling for almost a century. The phenomenological approach in psychotherapy originated in the works of Martin Heidegger, Ludwig Binswanger, Medard Boss and Viktor Frankl, and it has been committed to account for the existential possibilities and limitations of one’s life. EPP provides philosophically rich interpretations and empowers counseling techniques to assist mentally suffering individuals by finding meaning and purpose of life. The approach has proven to be effective in treating mood and anxiety disorders. This narrative review article demonstrates the development of EPP, the therapeutic methodology, evidence-based accounts of its curative techniques, current understanding of mood and anxiety disorders in neurological science, and a possible converging path to translate and integrate meaning-centered psychotherapy and neuroscience, concluding that the existential phenomenological psychotherapy potently plays a synergistic role with the currently prevailing medication-based approaches for the treatment of mood and anxiety disorders.


Author(s):  
Lehel Balogh ◽  
Masaru Tanaka ◽  
Nóra Török ◽  
László Vécsei ◽  
Shigeru Taguchi

Psychotherapy is a comprehensive biological treatment modifying complex underlying cognitive, emotional, behavioral, and regulatory responses in the brain, leading patients with mental illness to a new interpretation of the sense of self and others. Psychotherapy is an art of science integrated with psychology and/or philosophy. Neuroscience is a multidisciplinary science of the neuron, the glial cells including oligodendrocytes, ependymal cells, and astrocytes and the neural circuits to understand learning, memory, behavior, perception, and consciousness. Both psychotherapy and neuroscience deal with the brain; nevertheless, they continue to stay polarized far. Existential phenomenological psychotherapy (EPP) has been in the forefront of meaning-centered counseling for almost a century. The phenomenological approach in psychotherapy originated in the works of Martin Heidegger, Ludwig Binswanger, Medard Boss and Viktor Frankl, and it has been committed to account for the existential possibilities and limitations of one’s life. EPP provides philosophically rich interpretations and empowers counseling techniques to assist mentally suffering individuals by finding meaning and purpose of life. The approach has proven to be effective in treating mood and anxiety disorders. This review article demonstrates the development of EPP, the therapeutic methodology, evidence-based accounts of its curative techniques, current understanding of mood and anxiety disorders in neuroscience, and a possible converging path to translate and integrate meaning-centered psychotherapy and neuroscience, concluding that the existential phenomenological approach in psychotherapy is a viable and potent alternative to the currently prevailing medication-based approaches.


2011 ◽  
Vol 91 (3) ◽  
pp. 1009-1022 ◽  
Author(s):  
Mansi Vithlani ◽  
Miho Terunuma ◽  
Stephen J. Moss

Inhibition in the adult mammalian central nervous system (CNS) is mediated by γ-aminobutyric acid (GABA). The fast inhibitory actions of GABA are mediated by GABA type A receptors (GABAARs); they mediate both phasic and tonic inhibition in the brain and are the principle sites of action for anticonvulsant, anxiolytic, and sedative-hypnotic agents that include benzodiazepines, barbiturates, neurosteroids, and some general anesthetics. GABAARs are heteropentameric ligand-gated ion channels that are found concentrated at inhibitory postsynaptic sites where they mediate phasic inhibition and at extrasynaptic sites where they mediate tonic inhibition. The efficacy of inhibition and thus neuronal excitability is critically dependent on the accumulation of specific GABAAR subtypes at inhibitory synapses. Here we evaluate how neurons control the number of GABAARs on the neuronal plasma membrane together with their selective stabilization at synaptic sites. We then go on to examine the impact that these processes have on the strength of synaptic inhibition and behavior.


Author(s):  
Jelena Stojanov ◽  
Miodrag Stankovic ◽  
Olivera Zikic ◽  
Matija Stankovic ◽  
Aleksandar Stojanov

Objective The coronavirus disease 2019 (COVID-19) appears to be the largest pandemic of our times. The aim was to recognize the risk factors for nonpsychotic postpartum mood and anxiety disorders (NPMADs) in women during the pandemic and state of emergency police lockdown in Serbia. Methods We assessed 108 postpartum women who completed the Edinburgh Postnatal Depression Scale (EPDS) and an additional survey constructed for this study. We also used the additional, previously mentioned survey, in 67 healthy age-matched women with children who were ≥2 years of age. The additional survey allowed us to gain insight into the impact of the pandemic as well as postpartum period on the risk of NPMADs. Results In 16 (14.8%) subjects we found a score ≥10 on EPDS. Higher rates on the EPDS were noticed in elderly, single, and unemployed, women who lost their jobs due to the pandemic, or women who were dissatisfied with their household income (p < 0.05). The risk of NPMADs was linked significantly to quarantine, and social isolation, the absence of social support, as well as having emotional problems. Postpartum women, compared to non-postpartum women, were more anxious and had feelings of helplessness during social isolation. Conclusion Understanding the factors that increase the risk of NPMADs during the pandemic could help prevent mental disorders during a possible future pandemic.


2014 ◽  
Vol 21 (9) ◽  
pp. 721-730 ◽  
Author(s):  
Gyöngyvér Dallos ◽  
Mónika Miklósi ◽  
Ágnes Keresztény ◽  
Szabina Velő ◽  
Dóra Szentiványi ◽  
...  

Objective: Our aim was to evaluate the Quality of Life (QoL) of treatment naïve children with ADHD. Method: Data from 178 parent–child dyads were analyzed using multiple regression to assess the relationships between QoL, and characteristics of ADHD and comorbid psychopathology. Results: Lower self-reported QoL was associated with female gender, higher age, more symptoms of anxiety and trauma-related disorders in dimensional approach, and with the comorbid diagnoses of trauma-related disorders and oppositional defiant disorder (ODD)/conduct disorder (CD) in categorical approach. Lower parent-reported QoL was related to older age and increasing number of symptoms of mood and anxiety disorders on one hand, and any diagnosis of mood and anxiety disorders and ODD/CD on the other. Conclusion: Our results draw the attention to the importance of taking into account age, gender, and both self- and parent reports when measuring QoL of children with ADHD and both dimensional and categorical approaches should be used.


2015 ◽  
pp. S275-S282 ◽  
Author(s):  
M. DUŠKOVÁ ◽  
M. HILL ◽  
M. BIČÍKOVÁ ◽  
M. ŠRÁMKOVÁ ◽  
D. ŘÍPOVÁ ◽  
...  

The mood and behavior of individuals result from an orchestra of many factors. Among them steroids play an important role; however, only several common hormones have been investigated in this respect. It has been demonstrated that some steroid metabolites long considered merely the products of steroid hormone metabolism in fact possess considerable activity in the CNS. For this reason we studied the steroid metabolome including 50 analytes in 20 men with depression, 20 men with anxiety and 30 healthy controls. Significant differences were found not only between controls and men with either depression or anxiety, but also between men with depression and anxiety. Particularly striking were those steroids until now not generally associated with depression or anxiety, namely conjugated steroid forms, especially sulfates.


Author(s):  
Oliver J Robinson ◽  
Rebecca Bond ◽  
Jonathan P Roiser

Stress can precipitate the onset of mood and anxiety disorders. This may occur, at least in part, via a modulatory effect of stress on decision-making. Some individuals are, however, more resilient to the effects of stress than others. The mechanisms underlying such vulnerability differences are nevertheless unknown. In this study we attempted to begin quantifying individual differences in vulnerability by exploring the effect of experimentally induced stress on decision-making. Threat of unpredictable shock was used to induce stress in healthy volunteers (N=47) using a within-subjects, within-session design, and its impact on a financial decision-making task (the Iowa Gambling Task) was assessed alongside anxious and depressive symptomatology. As expected, participants learned to select advantageous decks and avoid disadvantageous decks. Importantly, we found that stress provoked a pattern of harm-avoidant behaviour (decreased selection of disadvantageous decks) in individuals with low levels of trait anxiety. By contrast, individuals with high trait anxiety demonstrated the opposite pattern: stress-induced risk-seeking (increased selection of disadvantageous decks). These contrasting influences of stress depending on mood and anxiety symptoms might provide insight into vulnerability to common mental illness. In particular, we speculate that those who adopt a more harm-avoidant strategy may be better able to regulate their exposure to further environmental stress, reducing their susceptibility to mood and anxiety disorders. The threat of shock paradigm we employed might therefore hold promise as a ‘stress-test’ for determining individual vulnerability to mood and anxiety disorders.


2017 ◽  
Author(s):  
Jessica Aylward ◽  
Claire Hales ◽  
Emma Robinson ◽  
Oliver J Robinson

AbstractBackgroundMood and anxiety disorders are ubiquitous but current treatment options are ineffective for large numbers of sufferers. Moreover, recent years have seen a number of promising pre-clinical interventions fail to translate into clinical efficacy in humans. Improved treatments are unlikely without better animal-human translational pipelines. Here, we directly adapt–i.e. back-translate - a rodent measure of negative affective bias into humans, and explore its relationship with a)pathological mood and anxiety symptoms (study one) and b)transient induced anxiety (study two).MethodParticipants who met criteria for mood or anxiety disorder symptomatology according to a face-to-face neuropsychiatric interview were included in the symptomatic group. N = 77(47 asymptomatic; Female = 21; 30 symptomatic; Female = 25) participants completed study one and N = 47 asymptomatic participants (25 female) completed study two. Outcome measures were choice ratios, reaction times and parameters recovered from a computational model of reaction time; the drift diffusion model (DDM).ResultsSymptomatic individuals demonstrated increased negative affective bias relative to asymptomatic individuals (proportion high reward = 0.42(SD = 0.14), and 0.53(SD = 0.17), respectively) as well as reduced DDM drift rate (p = 0.004). No significant effects were observed for the within-subjects anxiety-induction in study 2.ConclusionHumans with pathological anxiety symptoms directly mimic rodents undergoing anxiogenic manipulation. The lack of sensitivity to transient anxiety suggests the paradigm may, moreover, be primarily sensitive to clinically relevant symptoms. Our results establish a direct translational pipeline (and candidate therapeutics screen) from negative affective bias in rodents to pathological mood and anxiety symptoms in humans, and link it to a computational model of reaction time.


Author(s):  
Nieves Gomis Selva ◽  
Carolina Gonzálvez Maciá ◽  
María Vicent Juan ◽  
Mª Isabel Gómez Núñez ◽  
Nelly Lagos San Martín

Abstract.Just the existence of school refusal associated with stress and anxiety disorders in child age should make us think about the responsibility we have as adults (families, teachers, educators, etc.) to promote healthy, safe and balanced contexts help to: a) prevent these disorders by promoting a comprehensive and harmonious development of children and/or, b) minimize the impact of adverse experiences or contexts may have on the child. This study seeks to highlight the potential benefits of training strategies, joint participation and school-family collaboration based on the Multiple Intelligences’s theory to prevent and/or minimize the stress and anxiety experienced by many children with symptoms of school refusal. The conclusions are based on studies that show the existence of different profiles of intelligence from an early age (Ballester, 2004; Gomis, 2007; Valero, 2007) and are based and complemented from the data study provided by 144 families about the strengths and weaknesses of their children as much in school and at home activities, as well as activities or personality traits that manifest children outside school hours and that could affect performance and behavior in the school environment. The results provide valuable information about the expectations of parents and perceptions of child characteristics that may cause school refusal. Similarly, the study of the application of theory in educational contexts (Del Pozo, 2005, 2009, 2013) shows proposals for action from the school setting mechanisms, procedures and operational standards to work from the center in collaboration with the families to prevent and/or minimize school refusal.Keywords: school refusal, family perception, multiple intelligences.Resumen.El simple hecho de plantear la existencia de rechazo escolar asociado a trastornos de estrés y ansiedad en edad infantil tiene que hacernos reflexionar sobre la responsabilidad que tenemos todos los adultos (familias, docentes, educadores, etc.) de favorecer contextos sanos, seguros y equilibrados que ayuden a: a) prevenir dichos trastornos favoreciendo un desarrollo global y armónico de la infancia y/o, b) minimizar el impacto que vivencias o contextos desfavorables puedan tener en el niño y la niña. Esta comunicación pretende dar a conocer los beneficios que pueden aportar estrategias de formación, participación y colaboración conjunta escuela-familia basadas en la teoría de las Inteligencias Múltiples para prevenir y/o minimizar el estrés o la ansiedad que sufren muchos niños y niñas que presentan síntomas de rechazo escolar. Las conclusiones parten de investigaciones que evidencian la existencia de perfiles de inteligencia diferenciados desde edades tempranas (Ballester, 2004; Gomis, 2007; Valero, 2007) y se fundamentan y complementan a partir del estudio de datos aportados por 144 familias sobre las potencialidades y debilidades de sus hijos e hijas tanto en actividades escolares como en el hogar así como actividades o rasgos de personalidad que los niños y niñas manifiestan fuera del horario escolar y que pueden influir en su rendimiento y conducta en el ambiente escolar. Los resultados obtenidos aportan información muy valiosa sobre las expectativas que tienen los padres así como percepciones sobre características del niño o niña que puedan ser causa de rechazo escolar. Del mismo modo, el estudio de la aplicación de la teoría en contextos educativos (Del Pozo, 2005, 2009, 2013) plantea propuestas de actuación desde la escuela estableciendo mecanismos, procedimientos y pautas de actuación para trabajar desde el centro y en colaboración con las familias para prevenir y/o minimizar el rechazo escolar.Palabras clave: rechazo escolar, percepción familiar, inteligencias múltiples.


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