scholarly journals Immunosensing Based on Optical Fiber Technology: Recent Advances

Biosensors ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 305
Author(s):  
Maria Simone Soares ◽  
Miguel Vidal ◽  
Nuno F. Santos ◽  
Florinda M. Costa ◽  
Carlos Marques ◽  
...  

The evolution of optical fiber technology has revolutionized a variety of fields, from optical transmission to environmental monitoring and biomedicine, given their unique properties and versatility. For biosensing purposes, the light guided in the fiber core is exposed to the surrounding media where the analytes of interest are detected by different techniques, according to the optical fiber configuration and biofunctionalization strategy employed. These configurations differ in manufacturing complexity, cost and overall performance. The biofunctionalization strategies can be carried out directly on bare fibers or on coated fibers. The former relies on interactions between the evanescent wave (EW) of the fiber and the analyte of interest, whereas the latter can comprise plasmonic methods such as surface plasmon resonance (SPR) and localized SPR (LSPR), both originating from the interaction between light and metal surface electrons. This review presents the basics of optical fiber immunosensors for a broad audience as well as the more recent research trends on the topic. Several optical fiber configurations used for biosensing applications are highlighted, namely uncladded, U-shape, D-shape, tapered, end-face reflected, fiber gratings and special optical fibers, alongside practical application examples. Furthermore, EW, SPR, LSPR and biofunctionalization strategies, as well as the most recent advances and applications of immunosensors, are also covered. Finally, the main challenges and an outlook over the future direction of the field is presented.

2021 ◽  
Vol 11 (7) ◽  
pp. 3254
Author(s):  
Marco Pisco ◽  
Francesco Galeotti

The realization of advanced optical fiber probes demands the integration of materials and structures on optical fibers with micro- and nanoscale definition. Although researchers often choose complex nanofabrication tools to implement their designs, the migration from proof-of-principle devices to mass production lab-on-fiber devices requires the development of sustainable and reliable technology for cost-effective production. To make it possible, continuous efforts are devoted to applying bottom-up nanofabrication based on self-assembly to decorate the optical fiber with highly ordered photonic structures. The main challenges still pertain to “order” attainment and the limited number of implementable geometries. In this review, we try to shed light on the importance of self-assembled ordered patterns for lab-on-fiber technology. After a brief presentation of the light manipulation possibilities concerned with ordered structures, and of the new prospects offered by aperiodically ordered structures, we briefly recall how the bottom-up approach can be applied to create ordered patterns on the optical fiber. Then, we present un-attempted methodologies, which can enlarge the set of achievable structures, and can potentially improve the yielding rate in finely ordered self-assembled optical fiber probes by eliminating undesired defects and increasing the order by post-processing treatments. Finally, we discuss the available tools to quantify the degree of order in the obtained photonic structures, by suggesting the use of key performance figures of merit in order to systematically evaluate to what extent the pattern is really “ordered”. We hope such a collection of articles and discussion herein could inspire new directions and hint at best practices to fully exploit the benefits inherent to self-organization phenomena leading to ordered systems.


Fibers ◽  
2019 ◽  
Vol 7 (5) ◽  
pp. 50 ◽  
Author(s):  
Walter Belardi

The possibility of guiding light in air has fascinated optical scientists and engineers since the dawn of optical fiber technology [...]


2013 ◽  
Vol 823 ◽  
pp. 153-156
Author(s):  
Fei Wu ◽  
Rui Tao Li ◽  
Bo Pang ◽  
Cong Jun Li

Nowadays, as a new type of optical fiber devices, with flexible structure characteristic and steady frequency-selecting performance among the key support device areas of optic fiber technology, Fiber Bragg Grating (FBG) is rapidly developed as an very important basic device.Therefore, the study of phase mask plate which will be good for the mass production of the optical fiber gratings is becoming a central issue. The appearance of phase mask plate technology makes the industrialized production of fiber optical gratings with a stable wavelength possible. This paper based on the optical fiber gratings written online is mainly about the study of related servo control system. By the design of the servo control system of phase mask plate, we will get the ideal purposes that phase mask plate is precisely positioned, torque of plate is increased and the time of picking any plate is undifferentiated.


2005 ◽  
Author(s):  
Andrew D. Yablon

Several recent technological breakthroughs have led to a renaissance of interest in optical fibers, which are now widely used for applications as diverse as telecommunications, medicine, and sensing. Contemporary optical fiber technology is inherently multidisciplinary, inter-relating fields as diverse as glass science, mechanical engineering, and optics. This paper reviews several aspects of silica optical fiber technology in which thermal transport plays a critical role. Future research directions are discussed.


1987 ◽  
Vol 41 (5) ◽  
pp. 779-785 ◽  
Author(s):  
Brad Tenge ◽  
B. R. Buchanan ◽  
D. E. Honigs

Chemical sensing in remote, hostile environments is possible with optical fiber technology. Telecommunications optical fiber transmits light in the near-infrared region. The least amount of attenuation of transmitted power is between 1050 nm and 1600 nm. It is a natural step to apply near-infrared analysis techniques to data remotely collected over optical fibers. A feasibility study is conducted to see how well calibration techniques, Multiple Linear Regression with either Step-up search or All Possible Combinations search, perform in the fiber optic region of the near-infrared. Calibration in the 1131–1531 nm region is compared to calibration in the 1131–2531 nm region. The latter region is considered more information-rich than the former. In spite of this, examination of the predictive power of calibration models formed strictly from fiberoptic-region absorbance data indicates that this region contains useful analytical informaton.


2013 ◽  
Vol 59 (2) ◽  
pp. 131-140 ◽  
Author(s):  
Ryszard S. Romaniuk ◽  
Waldemar Wójcik

Abstract The Conference on Optical Fibers and Their Applications, Nałȩczów 2012, in its 14th edition, which has been organized since more than 35 years, has summarized the achievements of the local optical fiber technology community, for the last year and a half. The conference specializes in developments of optical fiber technology, glass and polymer, classical and microstructured, passive and active. The event gathered around 100 participants. There were shown 60 presentations of 20 research and application groups active in fiber photonics, originating from academia and industry. Topical tracks of the Conference were: photonic materials, planar waveguides, passive and active optical fibers, propagation theory in nonstandard optical fibers, and new constructions of optical fibers. A panel discussion concerned teaching in fiber photonics. The conference was accompanied by a school on Optical Fiber Technology. The paper summarizes the chosen main topical tracks of the conference on Optical Fibers and Their Applications, Nałȩczów 2012. The papers from the conference presentations will be published in Proc. SPIE, including a conference version of this paper. The next conference of this series is scheduled for January 2014 in Białowie˙za.


2021 ◽  
Vol 11 (2) ◽  
pp. 141-157
Author(s):  
Wei Jin ◽  
Haihong Bao ◽  
Pengcheng Zhao ◽  
Yan Zhao ◽  
Yun Qi ◽  
...  

AbstractWith micro- and nano-structured optical fibers, parts-per-million to parts-per-trillion level gas detection has been demonstrated for a range of gases such as methane, acetylene, ethane, carbon monoxide, hydrogen, and oxygen. We review the recent development in optical fiber gas cells and gas detection systems based on direct absorption, photothermal, photoacoustic, and stimulated Raman spectroscopies.


2020 ◽  
Vol 12 (1) ◽  
pp. 4
Author(s):  
Yuqing Li ◽  
Kuo Li ◽  
Guoyong Liu ◽  
Juan Tian ◽  
Yanchun Wang

Fiber Bragg grating (FBG) accelerometers using transverse forces have higher sensitivity but lower resonant frequency than ones using axial forces. By shortening the distance between the two fixed ends of the FBG, the resonant frequency can be improved without lowing the sensitivity. Here, a compact FBG accelerometer using transverse forces with a slightly pre-relaxed FBG and 25mm distance between the two fixed ends has been demonstrated with the crest-to-trough sensitivity 1.1nm/g at 5Hz and the resonant frequency 42Hz. It reveals that making the FBG slightly pre-relaxed rather than pre-stretched also improves the tradeoff between the sensitivity and resonant frequency. Full Text: PDF References:Kawasaki, B. S. , Hill, K. O , Johnson, D. C. , & Fujii, Y. , "Narrow-band Bragg reflectors in optical fibers", Optics Letters 3, 66 (1978) [CrossRef]K. O. Hill, and G. Meltz, "Fiber Bragg grating technology fundamentals and overview", Journal of Lightwave Technology 15, 1263 (1997) [CrossRef]B. Lee, "Review of the present status of optical fiber sensors", Optical Fiber Technology, 9, 57-79 (2003) [CrossRef]Laudati, A. , Mennella, F. , Giordano, M. , D"Altrui, G. , Tassini, C. C. , & Cusano, A., "A Fiber-Optic Bragg Grating Seismic Sensor", IEEE Photonics Technology Letters, 19, 1991 (2007) [CrossRef]P. F. Costa Antunes, C. A. Marques, H. Varum, and P. S. Andre, "Biaxial Optical Accelerometer and High-Angle Inclinometer With Temperature and Cross-Axis Insensitivity", IEEE Sens. J. 12, 2399 (2012) [CrossRef]Guo, Y. , Zhang, D. , Zhou, Z. , Xiong, L. , & Deng, X., "Welding-packaged accelerometer based on metal-coated FBG", Chinese Optics Letters, 11, 21 (2013). [CrossRef]Zhang, Y. , Zhang, W. , Zhang, Y. , Chen, L. , Yan, T. , & Wang, S. , et al., "2-D Medium–High Frequency Fiber Bragg Gratings Accelerometer", IEEE Sensors Journal, 17, 614(2017) [CrossRef]Xiu-bin Zhu, "A novel FBG velocimeter with wind speed and temperature synchronous measurement", Optoelectronics Letters, 14, 276-279 (2018) [CrossRef]Li, K. , Yau, M. H. , Chan, T. H. T. , Thambiratnam, D., "Fiber Bragg grating strain modulation based on nonlinear string transverse-force amplifier", & Tam, H. Y. , Optics Letters, 38, 311 (2013) [CrossRef]Li, K. , Chan, T. H. T. , Yau, M. H. , Nguyen, T. , Thambiratnam, D. P. , & Tam, H. Y., "Very sensitive fiber Bragg grating accelerometer using transverse forces with an easy over-range protection and low cross axial sensitivity", Applied Optics, 52, 6401 (2013) [CrossRef]Li, K. , Chan, T. H. T. , Yau, M. H. , Thambiratnam, D. P. , & Tam, H. Y., "Biaxial Fiber Bragg Grating Accelerometer Using Axial and Transverse Forces", IEEE Photonics Technology Letters, 26, 1549 (2014). [CrossRef]Li, K. , Chan, T. H. , Yau, M. H. , Thambiratnam, D. P. , & Tam, H. Y., "Experimental verification of the modified spring-mass theory of fiber Bragg grating accelerometers using transverse forces", Applied Optics, 53, 1200-1211(2014) [CrossRef]


Author(s):  
Nélia Jordão Alberto ◽  
Lúcia Maria Botas Bilro ◽  
Paulo Fernando da Costa Antunes ◽  
Cátia Sofia Jorge Leitão ◽  
Hugo Filipe Teixeira Lima ◽  
...  

In the last years, optical fiber based sensors and systems for ehealthcare attracted the attention of the scientific community. Over this chapter, optical fiber technology is presented, referring the different types of optical fibers, its main characteristics, and advantages over other sensing methodologies. In addition, optical fiber based sensors and sensing techniques are discussed and several works reported in the literature are reviewed showing that they are a valuable technique to improve healthcare service to the community and as a potential solution to answer different problems. The final section of the chapter consists of the description of three applications of optical sensors in healthcare, namely monitoring of human joint movement, measuring strain of biological tissues, and characterization of medical materials.


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