scholarly journals Robust SERS Platforms Based on Annealed Gold Nanostructures Formed on Ultrafine Glass Substrates for Various (Bio)Applications

Biosensors ◽  
2019 ◽  
Vol 9 (2) ◽  
pp. 53 ◽  
Author(s):  
Lan Zhou ◽  
Simone Poggesi ◽  
Giuliocesare Casari Bariani ◽  
Rakesh Mittapalli ◽  
Pierre-Michel Adam ◽  
...  
Keyword(s):  
Surface Enhanced Raman Spectroscopy ◽  
Thin Layers ◽  
Gold Nanostructures ◽  
Hot Plate ◽  
Glass Substrates ◽  
Model Molecule ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
The Stability ◽  
First Time

In this study, stable gold nanoparticles (AuNPs) are fabricated for the first time on commercial ultrafine glass coverslips coated with gold thin layers (2 nm, 4 nm, 6 nm, and 8 nm) at 25 °C and annealed at high temperatures (350 °C, 450 °C, and 550 °C) on a hot plate for different periods of time. Such gold nanostructured coverslips were systematically tested via surface enhanced Raman spectroscopy (SERS) to identify their spectral performances in the presence of different concentrations of a model molecule, namely 1,2-bis-(4-pyridyl)-ethene (BPE). By using these SERS platforms, it is possible to detect BPE traces (10−12 M) in aqueous solutions in 120 s. The stability of SERS spectra over five weeks of thiol-DNA probe (2 µL) deposited on gold nano-structured coverslip is also reported.

Electrochemical surface-enhanced Raman spectroscopy (EC-SERS) study of the interaction between protein aggregates and biomimetic membranes

2018 ◽  
Vol 20 (6) ◽  
pp. 4513-4526 ◽  
Author(s):  
Reem Ahmed Karaballi ◽  
Soraya Merchant ◽  
Sasha R. Power ◽  
Christa L. Brosseau
Keyword(s):  
Raman Spectroscopy ◽  
Protein Aggregates ◽  
Surface Enhanced Raman Spectroscopy ◽  
Protein Aggregate ◽  
Biomimetic Membranes ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
First Time

EC-SERS is used for the first time to characterize protein aggregate–biomembrane interactions.

scholarly journals Gold Nanostructures for Surface-Enhanced Raman Spectroscopy, Prepared by Electrodeposition in Porous Silicon

Materials ◽  
2011 ◽  
Vol 4 (4) ◽  
pp. 791-800 ◽  
Author(s):  
Kazuhiro Fukami ◽  
Mohamed L. Chourou ◽  
Ryohei Miyagawa ◽  
Álvaro Muñoz Noval ◽  
Tetsuo Sakka ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Porous Silicon ◽  
Surface Enhanced Raman Spectroscopy ◽  
Gold Nanostructures ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

scholarly journals Electromagnetic Modelling of Raman Enhancement from Nanoscale Structures as a Means to Predict the Efficacy of SERS Substrates

2007 ◽  
Vol 2007 ◽  
pp. 1-10 ◽  
Author(s):  
Richard J. C. Brown ◽  
Jian Wang ◽  
Martin J. T. Milton
Keyword(s):  
Surface Enhanced Raman Spectroscopy ◽  
Sers Substrate ◽  
Structured Surfaces ◽  
Nanoscale Structures ◽  
Sers Substrates ◽  
Raman Enhancement ◽  
Electromagnetic Modelling ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
First Time

The requirement to optimise the balance between signal enhancement and reproducibility in surface enhanced Raman spectroscopy (SERS) is stimulating the development of novel substrates for enhancing Raman signals. This paper describes the application of finite element electromagnetic modelling to predict the Raman enhancement produced from a variety of SERS substrates with differently sized, spaced and shaped morphologies with nanometre dimensions. For the first time, a theoretical comparison between four major generic types of SERS substrate (including metal nanoparticles, structured surfaces, and sharp tips) has been performed and the results are presented and discussed. The results of the modelling are consistent with published experimental data from similar substrates.

pH Dependence of the Size and Shape of the Gold Nanoparticles Prepared by Peptides

2013 ◽  
Vol 785-786 ◽  
pp. 484-487
Author(s):  
Chun Rong Wang
Keyword(s):  
Electron Microscopy ◽  
Gold Nanoparticles ◽  
Ph Dependence ◽  
Surface Enhanced Raman Spectroscopy ◽  
Gold Nanostructures ◽  
Size And Shape ◽  
Transmission Electron ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Potential Applications

The size and shape of gold nanoparticles controlled by pH was studied in the reacted solutions containing peptides (NH2-Leu-Aib-Trp-Ome) as reducing agent. The resulting gold nanostructures were characterized by transmission electron microscopy (TEM), XRD and UV-vis-NIR spectra. Different shape of gold nanoparticles such as spheres, multipod and branch were prepared by changing the pH of solution. The resulting gold nanostructures may be have potential applications in the Surface Enhanced Raman Spectroscopy (SERS) and NIR-absorbing filters and coatings.

scholarly journals High optical enhancement in Au/Ag alloys and porous Au using Surface-Enhanced Raman spectroscopy technique

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
C. Awada ◽  
C. Dab ◽  
M. G. Grimaldi ◽  
A. Alshoaibi ◽  
F. Ruffino
Keyword(s):  
Raman Spectroscopy ◽  
Enhancement Factor ◽  
Specific Area ◽  
Surface Enhanced Raman Spectroscopy ◽  
Gold Nanostructures ◽  
Localized Surface Plasmon ◽  
Porous Gold ◽  
Alloy Particles ◽  
Surface Enhanced ◽  
Surface Enhanced Raman

AbstractWe report high optical enhancement in Ag/Au alloys and porous gold nanostructures using Surface Enhanced Raman Spectroscopy (SERS) technique. Scanning electron microscopy investigation shows the formation of Ag/Au alloys particles during irradiation of Ag–Au bilayer deposited on FTO (SnO2:F) substrate by laser fluency equal to 0.5 J/cm2 or 1.0 J/cm2 with 12 ns laser pulse duration. The dealloying process of these Au–Ag alloy particles leads to the formation of Au nanoporous particles. The obtained nanostructures were studied with SERS and revealed a promising enhancement factor in porous Au nanostructure and tunability of localized surface plasmon resonance. The highly dense strong hot spots and large specific area in porous structure of gold nanostructures is the origin of the highly enhancement factor observed experimentally and theoretically. A very good agreement between simulation and experimental results was found confirming the potential of Au/Ag alloys and particularly porous gold nanostructure in SERS application.

scholarly journals Characterization of Human Tear Fluid by Means of Surface-Enhanced Raman Spectroscopy

Sensors ◽  
2019 ◽  
Vol 19 (5) ◽  
pp. 1177 ◽  
Author(s):  
Carlo Camerlingo ◽  
Mikhail Lisitskiy ◽  
Maria Lepore ◽  
Marianna Portaccio ◽  
Daniela Montorio ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Surface Enhanced Raman Spectroscopy ◽  
Whole Body ◽  
Sources Of Information ◽  
Glass Substrates ◽  
Organic Components ◽  
Interesting Insight ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Unique Method

Tears are exceptionally rich sources of information on the health status of the eyes, as well as of whole body functionality, due to the presence of a large variety of salts and organic components whose concentration can be altered by pathologies, eye diseases and/or inflammatory processes. Surface enhanced Raman spectroscopy (SERS) provides a unique method for analyzing low concentrations of organic fluids such as tears. In this work, a home-made colloid of gold nanoparticles has been used for preparing glass substrates able to efficiently induce an SERS effect in fluid samples excited by a He–Ne laser ( λ = 633 nm). The method has been preliminary tested on Rhodamine 6G aqueous solutions at different concentrations, proving the possibility to sense substance concentrations as low as few μ M, i.e., of the order of the main tear organic components. A clear SERS response has been obtained for human tear samples, allowing an interesting insight into tear composition. In particular, aspartic acid and glutamic acid have been shown to be possible markers for two important human tear components, i.e., lactoferrin and lysozyme.

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