scholarly journals Bio-Recognition in Spectroscopy-Based Biosensors for *Heavy Metals-Water and Waterborne Contamination Analysis

Biosensors ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 96 ◽  
Author(s):  
Aloisi ◽  
Della Torre ◽  
De Benedetto ◽  
Rinaldi
Keyword(s):  
Heavy Metal Contamination ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Primary Source ◽  
Relevant Information ◽  
Surface Enhanced Raman Spectroscopy ◽  
Optical Biosensors ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Key Aspects

: Microsystems and biomolecules integration as well multiplexing determinations are key aspects of sensing devices in the field of heavy metal contamination monitoring. The present review collects the most relevant information about optical biosensors development in the last decade. Focus is put on analytical characteristics and applications that are dependent on: (i) Signal transduction method (luminescence, colorimetry, evanescent wave (EW), surface-enhanced Raman spectroscopy (SERS), Förster resonance energy transfer (FRET), surface plasmon resonance (SPR)); (ii) biorecognition molecules employed (proteins, nucleic acids, aptamers, and enzymes). The biosensing systems applied (or applicable) to water and milk samples will be considered for a comparative analysis, with an emphasis on water as the primary source of possible contamination along the food chain.

Intelligent Janus nanoparticles for intracellular real-time monitoring of dual drug release

Nanoscale ◽  
2016 ◽  
Vol 8 (12) ◽  
pp. 6754-6760 ◽  
Author(s):  
Han Cao ◽  
Yuhong Yang ◽  
Xin Chen ◽  
Zhengzhong Shao
Keyword(s):  
Energy Transfer ◽  
Real Time ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
Janus Particle ◽  
Janus Nanoparticles ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Dual Drug

A novel nanosystem, Janus particle Dox-CMR-MS/Au-6MP with opposing mesoporous silica and gold faces is able to monitor intracellular dual-drug responsive release in real time based on fluorescence resonance energy transfer (FRET) and surface-enhanced Raman scattering (SERS).

Bacterial detection and differentiation via direct volatile organic compound sensing with surface enhanced Raman spectroscopy

2017 ◽  
Author(s):  
Caitlin S. DeJong ◽  
David I. Wang ◽  
Aleksandr Polyakov ◽  
Anita Rogacs ◽  
Steven J. Simske ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Bacterial Infections ◽  
Direct Detection ◽  
Point Of Care ◽  
Surface Enhanced Raman Spectroscopy ◽  
E Coli ◽  
Recent Emergence ◽  
Surface Enhanced ◽  
Volatile Organic ◽  
Surface Enhanced Raman

Through the direct detection of bacterial volatile organic compounds (VOCs), via surface enhanced Raman spectroscopy (SERS), we report here a reconfigurable assay for the identification and monitoring of bacteria. We demonstrate differentiation between highly clinically relevant organisms: <i>Escherichia coli</i>, <i>Enterobacter cloacae</i>, and <i>Serratia marcescens</i>. This is the first differentiation of bacteria via SERS of bacterial VOC signatures. The assay also detected as few as 10 CFU/ml of <i>E. coli</i> in under 12 hrs, and detected <i>E. coli</i> from whole human blood and human urine in 16 hrs at clinically relevant concentrations of 10<sup>3</sup> CFU/ml and 10<sup>4</sup> CFU/ml, respectively. In addition, the recent emergence of portable Raman spectrometers uniquely allows SERS to bring VOC detection to point-of-care settings for diagnosing bacterial infections.

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