scholarly journals Sensorineural Hearing Loss as the Prominent Symptom in Meningeal Carcinomatosis

2021 ◽  
Vol 28 (5) ◽  
pp. 3240-3250
Author(s):  
Xiaoqin Huang ◽  
Yu Jia ◽  
Lidong Jiao
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Cranial Nerves ◽  
Case Fatality ◽  
Whole Brain Radiotherapy ◽  
Meningeal Carcinomatosis ◽  
Sensorineural Hearing ◽  
Initial Symptom ◽  
Brain Radiotherapy ◽  
Total Deafness

Sensorineural hearing loss (SNHL) has been reported rarely in patients with meningeal carcinomatosis (MC). We summarized the clinical data of eight MC patients with SNHL and 35 patients reported from publications. In the eight patients with SNHL, the medium onset age was 48 (range from 37 to 66) years and six (75%) were male. Seven (87.5%) suffered from headaches as the initial symptom, and they experienced SNHL during the first two months after the occurrence of headaches (0.5 to 2 months, average 1.5 months). The audiogram configuration was flat in three patients (37.5%) and showed total deafness in five patients (62.5%). The damage of cranial nerves VI (abducens) was observed in six patients (75%), and four patients (50%) had cranial nerves VII (facial) injury during the disease course. The percentage of damage of cranial nerves was higher than the patients without SNHL (VIth, 75.0% vs. 13.3%, p = 0.002 and VIIth 50.0% vs. 6.7%, p = 0.012). Four (50%) patients suffered from lung adenocarcinoma as primary tumor, two (25%) experienced stomach adenocarcinoma, one had colon cancer, and one patient was unknown. The symptom of SNHL improved after individualized therapy in four patients (focal radiotherapy and chemotherapy for three patients and whole brain radiotherapy for one patient), but all passed away from 2 to 11 months after diagnosis. Total deafness and flat hearing loss in audiogram were the common types of SNHL resulting from MC. MC patients with SNHL were more likely to suffer from the damage of other cranial nerves, especially to cranial nerves VI and VII. Treatment might improve SNHL, but not improve the case fatality rate.

scholarly journals Association of multiple sclerosis and sudden sensorineural hearing loss

2016 ◽  
Vol 2 ◽  
pp. 205521731665215 ◽  
Author(s):  
S Atula ◽  
ST Sinkkonen ◽  
R Saat ◽  
T Sairanen ◽  
T Atula
Keyword(s):  
Multiple Sclerosis ◽  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Normal Population ◽  
Cranial Nerves ◽  
Sudden Sensorineural Hearing Loss ◽  
Sensorineural Hearing ◽  
University Hospital ◽  
Initial Symptom ◽  
Mri Findings

Background Multiple sclerosis (MS) may affect other cranial nerves besides the optic nerve. Sudden sensorineural hearing loss (SSHL), possibly caused by a deficit in the auditory tract, including the vestibulocochlear nerve, is sometimes associated with MS. Objectives We aimed to assess the incidence of SSHL among MS patients, its frequency as an initial symptom of MS, and magnetic resonance imaging (MRI) findings associated with SSHL in MS. Methods We collected retrospectively all patients diagnosed with MS and SSHL at the Helsinki University Hospital between 2004 and 2014. Patients with both diagnoses were re-evaluated using hospital medical records, audiograms and head MRI scans. Results A total of 2736 patients were diagnosed with MS, 1581 patients with SSHL, and 18 patients (0.7% of all MS patients) with both; two patients presented with SSHL as an initial symptom of MS. The annual incidence of SSHL was 59.8/100 000 (95% confidence interval (CI) 37.7–94.9) in MS patients, and 12.4/100 000 (95% CI 11.8–13.0) in the normal population. Conclusion SSHL is a rare symptom of MS and is even less frequent as an initial symptom. Its incidence in MS patients, however, markedly exceeds that in the normal population.

Ethmoidal Adenocarcinoma Presenting as Sensorineural Hearing Loss

1993 ◽  
Vol 7 (5) ◽  
pp. 241-244
Author(s):  
Faustino Nuñez ◽  
Ignacio Alvarez ◽  
Carlos Suarez ◽  
Valentin Mateos ◽  
Dulce M. Campos ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Clinical Manifestation ◽  
Relevant Literature ◽  
Meningeal Carcinomatosis ◽  
Sensorineural Hearing ◽  
Histopathological Findings ◽  
Early Stages ◽  
Patient’S History ◽  
Bilateral Deafness

We present a case of ethmoidal adenocarcinoma which in early stages of the disease produced a meningeal carcinomatosis. Its first clinical manifestation, bilateral deafness, is exceptional. The patient's history and endoscopic and histopathological findings are presented and the relevant literature is reviewed.

MAIN ISSUES OF CHILDREN'S INCIDENCE OF ACUTE OTITIS MEDIA AND PROSPECTS TO SOLVE THEM

2021 ◽  
pp. 73-76
Author(s):  
O. O. Kulikova ◽  
Yu. V. Lozova
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Otitis Media ◽  
Rapid Development ◽  
Cranial Nerves ◽  
Acute Otitis Media ◽  
Sensorineural Hearing ◽  
Social Significance ◽  
Number Of Patients ◽  
Medical Histories

The problem of acute otitis media in children is relevant because of the prevalence, social significance, possibility of rapid development of both life−threatening intracranial and intralabyrinthine, mastoid complications, as well as acute or prolonged dysfunction of adjacent cranial nerves, especially auditory, vestibular ones. In order to determine the frequency of various forms of acute otitis media, the nature and extent of its complications in children of different ages there was conducted a retrospective analysis of medical histories of patients treated at the City Clinical Hospital № 30 Kharkiv within 2015−2019. There was stated that the biggest group was composed by the patients with a purulent form of the disease, a slightly smaller number of patients had secretory and viral processes. But when analyzing the data over the years, of interest is the fact that during the period when the number of purulent forms decreased, the number of viral ones increased. Complications include mastoiditis, acute sensorineural hearing loss, cerebrospinal fluid and hypertension and intoxication syndromes. It is important that in acute purulent and viral otitis there is an intoxication syndrome along with the manifestations of acute sensorineural hearing loss. Signs of vestibular dysfunction in children can be disguised as symptoms of intoxication, they are much more difficult to detect. Considering the fact that the snail and the labyrinth are washed by the same liquid, it is logical to assume that in this situation the vestibular analyzer suffers together with the auditory one. Therefore, along with otoneurological research it is necessary to apply instrumental methods for establishment of latent disturbances of function of the vestibular analyzer. According to the research results it was concluded that a more detailed study of vestibular analyzer dysfunction in children with acute otitis media, as they are disguised as symptoms of intoxication. Key words: acute otitis media, frequency, complications, vestibular disorders, children.

Superficial Siderosis of the Central Nervous System: A Neglected Cause of Sensorineural Hearing Loss

1992 ◽  
Vol 107 (1) ◽  
pp. 69-77 ◽  
Author(s):  
Steven M. Parnes ◽  
Susan A. Weaver
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Imaging Techniques ◽  
Cranial Nerves ◽  
Sensorineural Hearing ◽  
Superficial Siderosis ◽  
System A ◽  
The Central Nervous System

Superficial siderosis of the central nervous system is a rare, often unrecognized condition in which there is a deposition of intracellular and extracellular hemosiderin in the leptomeninges, subpial tissue, spinal cord, and cranial nerves as a result of chronic bleeding in the subarachnoid space. On the basis of our cases and a review of the literature, the majority of patients manifest sensorineural hearing loss in addition to cerebellar dysfunction, pyramidal tract signs, and progressive mental deterioration. Recent imaging techniques—particularly CT and MRI—can define the presence of iron deposition, confirming the diagnosis ante mortem. From post mortem specimens, histologic sections demonstrate severe damage to the eighth nerve, with microglial metabolism of iron. Cases will be presented to illustrate these points.

Pontine Tegmental Cap Dysplasia

2011 ◽  
Vol 145 (6) ◽  
pp. 992-998 ◽  
Author(s):  
Nilesh K. Desai ◽  
Lindsay Young ◽  
Mario A. Miranda ◽  
Joe Walter Kutz ◽  
Peter S. Roland ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Cochlear Implantation ◽  
Cranial Nerves ◽  
Internal Auditory Canal ◽  
Sensorineural Hearing ◽  
Imaging Findings ◽  
Membranous Labyrinth ◽  
Brainstem Response ◽  
Temporal Bones

Objectives. Pontine tegmental cap dysplasia (PTCD) is a rare congenital malformation. Clinical and imaging findings in 3 patients and the authors’ experience with bilateral cochlear implantation in 1 patient are described. Study Design. Retrospective review. Setting. Two tertiary medical centers. Subjects and Methods. Three patients were evaluated by an otolaryngologist and underwent magnetic resonance imaging (MRI) of the temporal bones and brain. High-resolution computed tomography (CT) scanning of the temporal bones was performed in 2 patients. Imaging findings of the brain, the presence and course of resolvable cranial nerves, the membranous labyrinth, and internal auditory canals were reviewed. Clinical data were reviewed. Results. All patients demonstrated typical brain characteristics of PTCD. Mild, bilateral cochlear dysplasia was noted in 2, and all had a normal vestibular labyrinth. The cochleovestibular nerves were universally absent bilaterally. The facial nerves were subjectively deficient bilaterally in 1 patient, unilaterally in the second patient, and normal in the third. An accessory canal for the seventh cranial nerve, referred to as a duplicated internal auditory canal, was present in all patients. Auditory brainstem response testing revealed profound bilateral sensorineural hearing loss in all of the patients; none suffered facial weakness. A single patient underwent bilateral cochlear implantation with only minimal response. Conclusion. The authors report 3 cases of PTCD with emphasis on imaging of the seventh and eighth cranial nerves and clinical neurotologic findings. All patients manifested duplicated internal auditory canals, a previously unreported finding in PTCD. Bilateral profound sensorineural hearing loss is due to absence of the cochleovestibular nerve. Prognosis for cochlear implantation is poor.

A Case of Meningeal Carcinomatosis with Initial Symptoms of Acute Sensorineural Hearing Loss and Rapid Turning Point

2015 ◽  
Vol 143 (0) ◽  
pp. 107-111
Author(s):  
Sawako Minemura ◽  
Kouta Wada ◽  
Toshihito Suda ◽  
Chiaki Arai ◽  
Masato Nagaoka ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Turning Point ◽  
Meningeal Carcinomatosis ◽  
Sensorineural Hearing ◽  
Initial Symptoms

scholarly journals Hubungan Kadar Low Density Lipoprotein Dengan Gangguan Pendengaran Sensorineural

2020 ◽  
Vol 5 (2) ◽  
pp. 115-127
Author(s):  
Nurfadhilah Amini Nasution ◽  
Muhammad Edy Syahputra Nasution ◽  
Siti Masliana Siregar ◽  
Des Suryani
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Low Density Lipoprotein ◽  
Cranial Nerves ◽  
Density Lipoprotein ◽  
Sensorineural Hearing ◽  
Low Density ◽  
Research Subjects ◽  
Chi Square ◽  
Cross Sectional

Abnormalities of lipid metabolism in hyperlipidemia are the cause of atherosclerotic plaque in the inner ear and cranial nerves VIII, which can cause sensorineural hearing loss. Based on previous research, this theory is still questionable. Objective: To determine the relationship of LDL levels with sensorineural hearing loss. Method: This study is an analytic study with a cross-sectional approach. The research sample was taken based on a categorical descriptive formula with a large sample of 38 people. The data obtained is the result of laboratory tests, physical examination of the ears, nose and throat and audiometry examination of pure tone. This research was conducted at Medan Haji General Hospital and Putri Hijau Hospital II Medan. The number of research subjects was determined using consecutive sampling techniques. Data were analyzed using chi square test statistics. Results: There was a significant correlation of LDL levels with sensorineural hearing loss with a value of p = 0.001. The highest age in this study was 50-60 years of age, the most sex was female, the highest degree of hearing loss was moderateConclusion: There is a significant relationship between LDL levels with sensorineural hearing loss.   Keywords: Audiometry, Hearing Loss, Sensorineural Hearing Loss, Low Density Lipoprotein, Lipid Profile  

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