scholarly journals Ketosis an Old Story Under a New Approach

Dairy ◽  
2020 ◽  
Vol 1 (1) ◽  
pp. 42-60
Author(s):  
Guanshi Zhang ◽  
Burim N. Ametaj

Ketosis, characterized by high concentrations of ketone bodies in the blood, urine, and milk, affects a considerable number of cows immediately after calving. Although much is known about ketosis, dairy cows continue to be affected in every herd world-wide. Cows affected by ketosis are treated with palliative treatments after the disease is diagnosed. This is a very expensive approach and costs the dairy industry extra expenses, contributing to lower profitability of dairy herds. In this review article, we summarize the mainstream view on ketosis, classification of ketosis into three types, current diagnostic approaches to ketosis, and the economic impact of ketosis on dairy farms. Additionally, we discuss the most recent applications of the new ‘omics’ science of metabolomics in studying the etiopathology of ketosis as well as its contribution in identification of novel screening or diagnostic biomarkers of ketosis.

Author(s):  
Oleksandr Ostrohliad

Purpose. The aim of the work is to consider the novelties of the legislative work, which provide for the concept and classification of criminal offenses in accordance with the current edition of the Criminal Code of Ukraine and the draft of the new Code developed by the working group and put up for public discussion. Point out the gaps in the current legislation and the need to revise individual rules of the project in this aspect. The methodology. The methodology includes a comprehensive analysis and generalization of the available scientific and theoretical material and the formulation of appropriate conclusions and recommendations. During the research, the following methods of scientific knowledge were used: terminological, logical-semantic, system-structural, logical-normative, comparative-historical. Results In the course of the study, it was determined that despite the fact that the amendments to the Criminal Code of Ukraine came into force in July of this year, their perfection, in terms of legal technology, raises many objections. On the basis of a comparative study, it was determined that the Draft Criminal Code of Ukraine needs further revision taking into account the opinions of experts in the process of public discussion. Originality. In the course of the study, it was established that the classification of criminal offenses proposed in the new edition of the Criminal Code of Ukraine does not stand up to criticism, since other elements of the classification appear in subsequent articles, which are not covered by the existing one. The draft Code, using a qualitatively new approach to this issue, retains the elements of the previous classification and has no practical significance in law enforcement. Practical significance. The results of the study can be used in law-making activities to improve the norms of the current Criminal Code, to classify criminal offenses, as well as to further improve the draft Criminal Code of Ukraine.


2021 ◽  
Vol 11 (4) ◽  
pp. 1855
Author(s):  
Franco Guzzetti ◽  
Karen Lara Ngozi Anyabolu ◽  
Francesca Biolo ◽  
Lara D’Ambrosio

In the construction field, the Building Information Modeling (BIM) methodology is becoming increasingly predominant and the standardization of its use is now an essential operation. This method has become widespread in recent years, thanks to the advantages provided in the framework of project management and interoperability. Hoping for its complete dissemination, it is unthinkable to use it only for new construction interventions. Many are experiencing what happens with the so-called Heritage Building Information Modeling (HBIM); that is, how BIM interfaces with Architectural Heritage or simply with historical buildings. This article aims to deal with the principles and working methodologies behind BIM/HBIM and modeling. The aim is to outline the themes on which to base a new approach to the instrument. In this way, it can be adapted to the needs and characteristics of each type of building. Going into the detail of standards, the text also contains a first study regarding the classification of moldable elements. This proposal is based on current regulations and it can provide flexible, expandable, and unambiguous language. Therefore, the content of the article focuses on a revision of the thinking underlying the process, also providing a more practical track on communication and interoperability.


2002 ◽  
Vol 2002 ◽  
pp. 18-18
Author(s):  
G. E. Pollott ◽  
J. D. Leaver

In recent years there has been an influx of Holstein genes into the UK dairy herd, largely achieved by a ‘grading up’ process using imported Holstein semen on Friesian cows. The research reported here investigates this process using performance records from UK dairy herds.


2021 ◽  
Vol 22 (4) ◽  
pp. 2024
Author(s):  
Natalie Turner ◽  
Pevindu Abeysinghe ◽  
Pawel Sadowski ◽  
Murray D. Mitchell

The reproductive status of dairy cows remains a challenge for dairy farmers worldwide, with impaired fertility linked to a significant reduction in herd profitability, due in part to impaired immunity, increased metabolic pressure, and longer postpartum anestrous interval (PPAI). Exosomes are nanovesicles released from a variety of cell types and end up in circulation, and carry proteins, bioactive peptides, lipids, and nucleic acids specific to the place of origin. As such, their role in health and disease has been investigated in humans and animals. This review discusses research into exosomes in the context of reproduction in dairy herds and introduces recent advances in mass-spectrometry (MS) based proteomics that have a potential to advance quantitative profiling of exosomal protein cargo in a search for early biomarkers of cattle fertility.


1985 ◽  
Vol 29 (2) ◽  
pp. 213 ◽  
Author(s):  
Rene T. A. Lysloff ◽  
Jim Matson
Keyword(s):  

Biomedicines ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 310
Author(s):  
Yuta Tezuka ◽  
Yuto Yamazaki ◽  
Yasuhiro Nakamura ◽  
Hironobu Sasano ◽  
Fumitoshi Satoh

For the last seven decades, primary aldosteronism (PA) has been gradually recognized as a leading cause of secondary hypertension harboring increased risks of cardiovascular incidents compared to essential hypertension. Clinically, PA consists of two major subtypes, surgically curable and uncurable phenotypes, determined as unilateral or bilateral PA by adrenal venous sampling. In order to further optimize the treatment, surgery or medications, diagnostic procedures from screening to subtype differentiation is indispensable, while in the general clinical practice, the work-up rate is extremely low even in the patients with refractory hypertension because of the time-consuming and labor-intensive nature of the procedures. Therefore, a novel tool to simplify the diagnostic flow has been recently in enormous demand. In this review, we focus on recent progress in the following clinically important topics of PA: prevalence of PA and its subtypes, newly revealed histopathological classification of aldosterone-producing lesions, novel diagnostic biomarkers and prediction scores. More effective strategy to diagnose PA based on better understanding of its epidemiology and pathology should lead to early detection of PA and could decrease the cardiovascular and renal complications of the patients.


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