scholarly journals Anthropometric Measurements and Frailty in Patients with Liver Diseases

Diagnostics ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 433 ◽  
Author(s):  
Hiroki Nishikawa ◽  
Kazunori Yoh ◽  
Hirayuki Enomoto ◽  
Naoto Ikeda ◽  
Nobuhiro Aizawa ◽  
...  
Keyword(s):  
Liver Diseases ◽  
Body Weight Loss ◽  
Skinfold Thickness ◽  
Cutoff Point ◽  
Operating Characteristics ◽  
Slow Walking ◽  
Arm Circumference ◽  
The Relationship ◽  
Triceps Skinfold Thickness ◽  
Slow Walking Speed

There have been scarce data regarding the relationship between frailty and anthropometry measurements (AMs) in patients with chronic liver diseases (CLDs). We aimed to elucidate the influence of AMs on frailty in CLDs (median age = 66 years, 183 men and 192 women). AMs included arm circumference, triceps skinfold thickness, calf circumference (CC), waist circumference, and body mass index. Frailty assessment was done by using five phenotypes (body weight loss, exhaustion, decreased muscle strength, slow walking speed, and low physical activity). Robust (frailty point 0), prefrail (frailty point 1 or 2), and frailty (frailty point 3 or more) were observed in 63 (34.4%), 98 (53.6%), and 22 (12.0%) of males, respectively, and 63 (32.8%), 101 (52.6%), and 28 (14.6%) of females, respectively. In receiver operating characteristics (ROC) curve analyses for the presence of frailty, CC had the highest area under the ROC (AUC) both in male (AUC = 0.693, cutoff point = 33.7 cm) and female (AUC = 0.734, cutoff point = 33.4 cm) participants. In the multivariate analysis associated with frailty, for the male participants, only the presence of liver cirrhosis (p = 0.0433) was identified to be significant, while among the female participants, serum albumin (p = 0.0444) and CC (p = 0.0010) were identified to be significant. In conclusion, CC can be helpful for predicting frailty, especially in female CLD patients.

scholarly journals Frailty and Sleep Disorder in Chronic Liver Diseases

Life ◽  
2020 ◽  
Vol 10 (8) ◽  
pp. 137
Author(s):  
Hiroki Nishikawa ◽  
Kazunori Yoh ◽  
Hirayuki Enomoto ◽  
Yoshinori Iwata ◽  
Takashi Nishimura ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Sleep Disorder ◽  
Liver Diseases ◽  
Body Weight Loss ◽  
Japanese Version ◽  
Chronic Liver ◽  
Chronic Liver Diseases ◽  
Sleep Complaints ◽  
Slow Walking ◽  
Slow Walking Speed

We aimed to investigate the association in frailty and sleep disorder as assessed by the Japanese version of Pittsburgh Sleep Quality Index (PSQI-J) in patients with chronic liver diseases (CLDs, n = 317, 141 males). Frailty was determined using the following five phenotypes: unintentional body weight loss, self-reported exhaustion, muscle weakness, slow walking speed, and low physical activity. Sleep disorder was defined as patients with PSQI-J score 6 or greater. Robust (phenotype, 0), prefrail (1 or 2 phenotypes) and frailty (3 phenotypes or greater) were observed in 101 (31.9%), 174 (54.9%) and 42 (13.2%), respectively. The median (interquartile range (IQR)) PSQI-J score was 4 (3, 7). Sleep disorder was found in 115 patients (36.3%). The median (IQR) PSQI-J scores in patients of the robust, prefrail, and frail groups were 3 (2, 5), 5 (3, 7), and 8 (4.75, 10.25), respectively (p < 0.0001 between any two groups and overall p < 0.0001). The ratios of sleep disorder in patients with robust, prefrail and frailty were 15.8% (16/101), 39.1% (68/174), and 73.8% (31/42), respectively (overall p < 0.0001). In conclusion, CLD patients with frailty can involve poorer sleep quality. As sleep disorder in CLDs is potentially remediable, future frailty-preventive strategies must take sleep complaints into account.

scholarly journals Close Correlation between Frailty and Depressive State in Chronic Liver Diseases

Medicina ◽  
2020 ◽  
Vol 56 (7) ◽  
pp. 319
Author(s):  
Hiroki Nishikawa ◽  
Kazunori Yoh ◽  
Hirayuki Enomoto ◽  
Yoshinori Iwata ◽  
Yoshiyuki Sakai ◽  
...  
Keyword(s):  
Body Weight Loss ◽  
Close Correlation ◽  
Clinical Syndrome ◽  
Chronic Liver ◽  
Depressive State ◽  
Slow Walking ◽  
Few Data ◽  
The Relationship ◽  
Slow Walking Speed ◽  
Frailty Score

Background and objectives: Few data with regard to the relevance between depression and frailty in chronic liver disease (CLD) patients are currently available. We aimed to elucidate the relationship between frailty and depression as evaluated by the Beck Depression Inventory—2nd edition (BDI-II) in CLD patients (n = 340, median age = 65.0 years). Methods: Frailty was defined as a clinical syndrome in which three or more of the following criteria were met: body weight loss, exhaustion, muscle weakness, slow walking speed and low physical activity. Depressive state was defined as BDI-II score 11 or greater. Results: Robust (frailty score = zero), prefrail (frailty score = one or two) and frailty were identified in 114 (33.5%), 182 (53.5%) and 44 (12.9%). The median BDI-II score was five. Depressive state was identified in 84 patients (24.7%). The median BDI-II scores in patients with robust, prefrail and frail traits were 2, 7 and 12.5 (robust vs. prefrail, p < 0.0001; prefrail vs. robust, p = 0.0003; robust vs. frail, p < 0.0001; overall p < 0.0001). The proportions of depressive state in patients with robust, prefrail and frail traits were 3.51%, 30.77% and 54.55% (robust vs. prefrail, p < 0.0001; prefrail vs. robust, p = 0.0046; robust vs. frail, p < 0.0001; overall p < 0.0001). BDI-II score significantly correlated with frailty score (rs = 0.5855, p < 0.0001). Conclusions: The close correlation between frailty and depression can be found in CLD. Preventing frailty in CLD should be approached both physiologically and psychologically.

scholarly journals Is total lymphocyte count related to nutritional markers in hospitalized older adults?

2017 ◽  
Vol 54 (1) ◽  
pp. 79-82 ◽  
Author(s):  
Vânia Aparecida LEANDRO-MERHI ◽  
Vitória Negri BRÁZ ◽  
José Luis Braga de AQUINO
Keyword(s):  
Older Adults ◽  
Lymphocyte Count ◽  
Skinfold Thickness ◽  
Total Lymphocyte Count ◽  
Nutritional Risk ◽  
Total Lymphocyte ◽  
Arm Circumference ◽  
Hospitalized Older Adults ◽  
Mid Upper Arm Circumference ◽  
Triceps Skinfold Thickness

ABSTRACT BACKGROUND Older patients are commonly malnourished during hospital stay, and a high prevalence of malnutrition is found in hospitalized patients aged more than 65 years. OBJECTIVE To investigate whether total lymphocyte count is related to other nutritional markers in hospitalized older adults. METHODS Hospitalized older adults (N=131) were recruited for a cross-sectional study. Their nutritional status was assessed by the Nutritional Risk Screening (NRS), anthropometry, and total lymphocyte count. The statistical analyses included the chi-square test, Fisher's exact test, and Mann-Whitney test. Spearman's linear correlation coefficient determined whether total lymphocyte count was correlated with the nutritional markers. Multiple linear regression determined the parameters associated with lymphocyte count. The significance level was set at 5%. RESULTS According to the NRS, 41.2% of the patients were at nutritional risk, and 36% had mild or moderate depletion according to total lymphocyte count. Total lymphocyte count was weakly correlated with mid-upper arm circumference (r=0.20507); triceps skinfold thickness (r=0.29036), and length of hospital stay (r= -0.21518). Total lymphocyte count in different NRS categories differed significantly: older adults who were not at nutritional risk had higher mean and median total lymphocyte count ( P =0.0245). Multiple regression analysis showed that higher lymphocyte counts were associated with higher triceps skinfold thicknesses and no nutritional risk according to the NRS. CONCLUSION Total lymphocyte count was correlated with mid-upper arm circumference, triceps skinfold thickness, and nutritional risk according to the NRS. In multiple regression the combined factors that remained associated with lymphocyte count were NRS and triceps skinfold thickness. Therefore, total lymphocyte count may be considered a nutritional marker. Other studies should confirm these findings.

scholarly journals Anthropometry and body composition of south Indian babies at birth

2006 ◽  
Vol 9 (7) ◽  
pp. 896-903 ◽  
Author(s):  
S Muthayya ◽  
P Dwarkanath ◽  
T Thomas ◽  
M Vaz ◽  
A Mhaskar ◽  
...  
Keyword(s):  
Body Composition ◽  
Birth Weight ◽  
Gestational Age ◽  
Skinfold Thickness ◽  
Fat Free Mass ◽  
Upper Arm ◽  
South Indian ◽  
Arm Circumference ◽  
Mid Upper Arm Circumference ◽  
The Relationship

AbstractObjectivesTo assess the consequences on body composition of increasing birth weight in Indian babies in relation to reported values in Western babies, and to assess the relationship between maternal and neonatal anthropometry and body composition.DesignProspective observational study.SettingBangalore City, India.SubjectsA total of 712 women were recruited at 12.5±3.1 weeks of gestation (mean±standard deviation, SD) and followed up until delivery; 14.5% were lost to follow-up. Maternal body weight, height, mid upper-arm circumference and skinfold thicknesses were measured at recruitment. Weight and body composition of the baby (skinfold thicknesses, mid upper-arm circumference, derived arm fat index and arm muscle index; AFI and AMI, respectively) were measured at birth in hospital.ResultsThe mean±SD birth weight of all newborns was 2.80±0.44 kg. Birth weight was significantly related to the triceps and subscapular skinfold thickness of the baby. In a small number of babies with large birth weight for gestational age, there was a relatively higher normalised AFI relative to AMI than for babies with lower or appropriate birth weight for gestational age. Maternal height and fat-free mass were significantly associated with the baby's length at birth.ConclusionsSkinfold thicknesses in Indian babies were similar to those reported in a Western population with comparable birth weights, and the relationship of AFI to birth weight appeared to be steeper in Indian babies. Thus, measures to increase birth weight in Indian babies should take into account possible adverse consequences on body composition. There were no significant relationships between maternal anthropometry and body composition at birth on multivariate analysis, except for sum of the baby's skinfold thicknesses and maternal fat-free mass (P<0.02).

scholarly journals The impact of in-hospital nutritional status deterioration on treatment outcome of adult gastroenterological patients

2016 ◽  
Vol 73 (8) ◽  
pp. 764-769
Author(s):  
Branka Roganovic ◽  
Sasa Peric ◽  
Snezana Jankovic
Keyword(s):  
Treatment Outcome ◽  
Nutritional Status ◽  
Independent Predictor ◽  
Skinfold Thickness ◽  
Favorable Outcome ◽  
Albumin Concentration ◽  
Status Assessment ◽  
The Impact ◽  
The Relationship ◽  
Triceps Skinfold Thickness

Background/Aim. In the current literature, data on impact of intrahospital changes in patients? nutritional status on the treatment outcome are limited. The aim of this study was to investigate the relationship between nutritional status deterioration and the treatment outcome among hospitalized gastroenterological patients. Methods. In 650 adult gastroenterological patients nutritional status on admission and at discharge was evaluated using the 6 nutritional status assessment parameters: body mass index, triceps skinfold thickness, mid-upper arm muscle circumference, serum albumin concentration, lymphocyte count and unintentional weight loss. The influence on treatment outcome was tested for the nutritional status on admission, nutritional status at discharge and intrahospital nutritional status deterioration. Results. The incidence of favorable outcome in the non-undernourished and undernourished patients on admission was in the range 93.4-97.3% and 81.2- 91.2%, respectively. The incidence of favorable outcome in the non-undernourished and undernourished patients at discharge was in the range 94-97.4% and 80.8-88.1%, respectively. Favorable outcomes were obtained in 95.6-98.9% of the patients without nutritional status deterioration and in 87.1-90.3% of the patients with nutritional status deterioration. Intrahospital nutritional status deterioration significantly influenced the outcome, no matter what assessment parameter had been used (p < 0.001 for all the applied parameters). Furthermore, only the deterioration of nutritional status was found to be an independent predictor of treatment outcome (multivariate analysis Forwald Wald, p ? 0.001; relative risk (RR) = 0.104-0.350; confidence intervals (CI) = 0.037-0.186/0.297-0.657). Conclusion. Deterioration of nutritional status is an independent predictor of adverse outcome.

SAT-026-Mid-arm circumference and triceps skinfold thickness independently predicts mortality in hospitalized patients with decompensated cirrhosis

2019 ◽  
Vol 70 (1) ◽  
pp. e636
Author(s):  
Camila Saueressig ◽  
Pâmela Kremer Ferreira ◽  
Joana Hoch Glasenapp ◽  
Thais Ortiz Hammes ◽  
Vivian Cristine Luft ◽  
...  
Keyword(s):  
Skinfold Thickness ◽  
Hospitalized Patients ◽  
Decompensated Cirrhosis ◽  
Arm Circumference ◽  
Triceps Skinfold Thickness

scholarly journals Adductor pollicis muscle as predictor of malnutrition in surgical patients

2014 ◽  
Vol 27 (1) ◽  
pp. 13-17 ◽  
Author(s):  
Camila Yandara Sousa Vieira de MELO ◽  
Silvia Alves da SILVA
Keyword(s):  
Weight Loss ◽  
Nutritional Assessment ◽  
Skinfold Thickness ◽  
Adductor Pollicis ◽  
Surgical Patients ◽  
Muscle Area ◽  
Cross Sectional ◽  
Adductor Pollicis Muscle ◽  
Arm Circumference ◽  
Triceps Skinfold Thickness

Background - In the compromised nutritional status, there is excessive skeletal muscle loss and decreased inflammatory response, contributing to increased morbidity and mortality and length of stay. Aim: To estimate the prevalence of malnutrition by measuring adductor pollicis muscle using cutoffs for surgical patients suggested in the literature. Methods: Cross-sectional study with 151 patients scheduled for elective surgical procedure. Nutritional assessment was performed by classical anthropometric measurements: arm circumference, triceps skinfold thickness, arm muscle circumference, corrected arm muscle area, BMI and percentage of weight loss and the extent of the adductor pollicis muscle in both hands. Results: The prevalence of malnutrition in patients was high. A significant association between nutritional diagnosis according to the measures of adductor pollicis muscle and arm circumference, BMI and triceps skinfold thickness but there was no association with arm muscular circumference, arm muscular area or percentage of weight loss. Conclusion: The adductor pollicis muscle has proved to be a good method to diagnose muscle depletion and malnutrition in surgical patients.

Weight Gain and Loss In Cancer Patients Undergoing Chemotherapy: Importance of Dose Adjustment

2021 ◽  
Vol 08 ◽  
Author(s):  
Maria Ayanny de Lima Fernandes ◽  
Andreza Tallyne de Aguiar Silva ◽  
Iago Dillion Lima Cavalcanti ◽  
Adrya Lúcia Peres Bezerra de Medeiros ◽  
Lígia Maria de Oliveira Lima ◽  
...  
Keyword(s):  
Weight Loss ◽  
Weight Gain ◽  
Cancer Patients ◽  
Antineoplastic Agent ◽  
Skinfold Thickness ◽  
Significant Loss ◽  
Arm Circumference ◽  
Gain And Loss ◽  
Triceps Skinfold Thickness ◽  
Anthropometric Assessment

Introduction: The established dose of chemotherapy is based on the values of the patient's body weight, where variations during treatment can increase the toxicity of chemotherapy, with the development of nephrotoxicity, among other toxicity profiles, as well as in cases of weight gain, patients may receive low doses and compromise the therapeutic response to the tumor. Objective: to evaluate weight gain and loss in cancer patients undergoing chemotherapy. Methods: Longitudinal analytical study with patients at the end of chemotherapy treatment of both genders. The type, location of the tumor and the antineoplastic agent used were collected from the medical records, as well as height and weight at the beginning of treatment. At the time of collection, anthropometric assessment was performed using body mass index, arm circumference, arm muscle circumference, triceps skinfold thickness and percentage of weight loss. Results: Among the patients included in the study, 47.5% had a weight gain of around 2.5 kg, while the remaining patients (52.5%) had a weight loss of around 2.8 kg. Of the patients who had GFR, 55.5% had severe PP, 33.4% had no significant loss and 11.1 had significant loss. In the current study, only 22% had a GFR <60ml/min/1.73m², but they would already need to readjust the medication calculation. Conclusion: It is important to evaluate body surface variations and also the GFR to adjust the dose of the antineoplastic agent and to prevent or minimize nephrotoxicity, as well as to reduce the risk of underdosing and inefficiency of the therapy.

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