scholarly journals The impact of in-hospital nutritional status deterioration on treatment outcome of adult gastroenterological patients

2016 ◽  
Vol 73 (8) ◽  
pp. 764-769
Author(s):  
Branka Roganovic ◽  
Sasa Peric ◽  
Snezana Jankovic

Background/Aim. In the current literature, data on impact of intrahospital changes in patients? nutritional status on the treatment outcome are limited. The aim of this study was to investigate the relationship between nutritional status deterioration and the treatment outcome among hospitalized gastroenterological patients. Methods. In 650 adult gastroenterological patients nutritional status on admission and at discharge was evaluated using the 6 nutritional status assessment parameters: body mass index, triceps skinfold thickness, mid-upper arm muscle circumference, serum albumin concentration, lymphocyte count and unintentional weight loss. The influence on treatment outcome was tested for the nutritional status on admission, nutritional status at discharge and intrahospital nutritional status deterioration. Results. The incidence of favorable outcome in the non-undernourished and undernourished patients on admission was in the range 93.4-97.3% and 81.2- 91.2%, respectively. The incidence of favorable outcome in the non-undernourished and undernourished patients at discharge was in the range 94-97.4% and 80.8-88.1%, respectively. Favorable outcomes were obtained in 95.6-98.9% of the patients without nutritional status deterioration and in 87.1-90.3% of the patients with nutritional status deterioration. Intrahospital nutritional status deterioration significantly influenced the outcome, no matter what assessment parameter had been used (p < 0.001 for all the applied parameters). Furthermore, only the deterioration of nutritional status was found to be an independent predictor of treatment outcome (multivariate analysis Forwald Wald, p ? 0.001; relative risk (RR) = 0.104-0.350; confidence intervals (CI) = 0.037-0.186/0.297-0.657). Conclusion. Deterioration of nutritional status is an independent predictor of adverse outcome.

2007 ◽  
Vol 64 (8) ◽  
pp. 549-553
Author(s):  
Branka Roganovic ◽  
Sasa Peric ◽  
Dino Tarabar

Background/Aim. There are no recommendations for the optimal nutritional status assessment parameters (NSAPs) in the current literature. The aim of this study was to define the optimal NSAPs for nutritional status assessing in gastroenterological patients on hospital admission. Methods. Nutritional status of 612 gastroenterological patients was evaluated at the admission using 6 NSAPs: unintentional weight loss (WL), body mass index (BMI), triceps skinfold thickness (TSF), mid-upper arm muscle circumference (MAMC), serum albumin concentration (ALB), and lymphocyte counts (LYM). According to their nutritive status, the patients were classified as well nourished (normally nourished and obese), moderately undernourished and severely undernourished. Based on the similarities and differences in the assessment results, obtained according to each of 6 parameters, the optimal nutritional assessment parameters were defined, separately for the well-nourished / undernourished patients and for moderately / severely undernourished patients. Results. The incidence of malnutrition was in the range 5.9-29.7%. The results based on MAMC, ALB, and LYM were similar (25.2- 29.7%; p > 0.05), while the results based on WL, BMI, and TSF differed significantly (5.9-19.9%; p = 0.001-0.015). The assessment based on BMI was the most severe criterion, while the assessment according to MAMC was the mildest criterion in selection of malnourished patients. The assessment according to MAMC was the mildest criterion for the selection of severe malnourished patients (severely malnouorished patients accounted for 70.l%), while BMI and LYM were the most severe criteria (severely malnouorished patients accounted for 22.2% and 27.3%, respectively). The results based on BMI and LYM were similar (Wilcoxon test; p > 0.05). Conclusion. Combining BMI with MAMC is sufficient for the assessment of the nutritional status of gastroenterological patients on admission, as well as for differentiation between severely malnourished and moderately malnourished patients. .


2021 ◽  
Vol 108 (Supplement_5) ◽  
Author(s):  
A T O Nickinson ◽  
I Black ◽  
J S M Houghton ◽  
R D Sayers

Abstract Introduction Serum albumin is a recognised marker of nutritional status. Whilst associated with post-operative outcomes, the relationship with amputation-related outcomes in chronic limb-threatening ischaemia (CLTI) remains unclear. It is also uncertain whether any relationship may be confounded by systematic inflammation. We aimed to investigate whether hypoalbuminaemia is associated with amputation-related outcomes and evaluate its relationship with other inflammatory markers. Method A retrospective study of patients managed for CLTI at a vascular centre between 01/01/2013–31/12/2015 was undertaken. Patients were identified from local coding databases. Patient demographics and comorbidities, results of admission bloods and procedural data were recorded from electronic records. Hypoalbuminaemia was defined as albumin concentration &lt;35 g/L. One-year amputation-free survival (AFS) was the primary outcome. Cox’s proportional hazard models were calculated to compare the risk of amputation/death. Linear regression was performed to investigate the relationship between albumin and other inflammatory markers. Result 374 patients were included (mean albumin concentration = 38.8g/L [SD = 5.2]), with 72 patients being hypoalbuminaemic. No differences were observed in sex (P=0.678), age (P=0.207), history of tissue loss (P=0.057), or cardiovascular comorbidities between groups, however a greater proportion of patients with hypoalbuminaemia had COPD (P=0.002). Patients with hypoalbuminaemia had a significantly higher combined risk of 1-year amputation/death compared to those with normal albumin concentration (HR 1.94, 95% CI 1.29–2.91). White cell count and CRP concentration were significant predictors of albumin concentration (r2=0.113, P&lt;0.001). Conclusion Hypoalbuminaemia is an important prognostic biomarker of AFS in CLTI, however this association may relate to a complex relationship between nutritional status and inflammation. Take-home Message Albumin is more than just a marker of nutritional status in patients with chronic limb-threatening ischaemia.


Author(s):  
Zahra Yaghtin ◽  
Richard Webb ◽  
Sayyed Saeid Khayyatzadeh

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has been the cause of a global pandemic. Given the impact of nutritional status upon immune function, it is crucial to understand the relationship between micronutrient intake and severity of the disease. This mini-review aimed to summarize the known associations between specific micronutrients (vitamin A, D, E, C and zinc, selenium and magnesium) and the health of coronavirus-infected patients. Low serum levels of these micronutrients are associated with the incidence and severity of SARS-CoV-2. However, further studies are needed to evaluate the outcomes of supplementation with these nutrients.


2014 ◽  
Vol 75 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Veronique Groleau ◽  
Maxime Thibault ◽  
Myriam Doyon ◽  
Eve-Emmanuelle Brochu ◽  
Claude C. Roy ◽  
...  

Purpose Malnutrition in hospitalized children has been reported since the late 1970s. The prevalence of acute and chronic malnutrition was examined in hospitalized patients in a general pediatric unit, and the impact and management of malnutrition were assessed. Methods The nutritional risk score (NRS) and nutritional status (NS) (weight, height, body mass index, and skinfold thickness) of children aged zero to 18 years were assessed upon hospital admission. Growth and energy intake were monitored every three days until discharge. Results A total of 173 children (median age three years, 88 girls) participated; 79.8% had a moderate to severe NRS and 13.3% were acutely and/or chronically malnourished. A high NRS was associated with a longer hospital stay in children older than three years (P<0.05), while a poor NS (weight for height percentile) was correlated with prolonged hospitalization in children aged three years or younger (P<0.05). Although weight did not change during hospitalization, a decrease in skinfolds was documented (n=43, P<0.05). Patients with a high NRS had lower energy intake than those not at risk. However, children with abnormal NS received 92.5% of recommended energy intake. Conclusions This study suggests that all children admitted to hospital should have an evaluation of their NRS and NS, so that they can receive appropriate nutrition interventions provided by a multidisciplinary nutrition team.


2021 ◽  
pp. 23-24
Author(s):  
Apeksha Patrikar ◽  
Swati Sharma ◽  
Rekha Shrivastava

Background: Wasting syndrome is very common in cancer due to metabolic and clinical factors and it affects half of the patients at the time of diagnosis. Early nutritional assessment can identify problems to help patients increase or maintain weight, improve their response to treatment, and reduce complications.This study aimed to determine the nutritional status of patients receiving chemotherapy. Methods: Aprospective study was conducted among 30 subjects between 30 and 70 years of age diagnosed with carcinoma breast and scheduled for rst cycle of chemotherapy. Nutritional status of each subject was assessed based on nutritional parameters i.e. Anthropometric [BMI (body mass index), MAMC (mid-arm muscle circumference), TSF (triceps skinfold thickness)], MAC (mid-arm circumference) and Biochemical [(Hb and Albumin)] measurements before the initiation of chemotherapy, and follow-up assessment was performed on the third week after the rst cycle of chemotherapy. Results: In this study it has been found that 90% of subjects suffered from weight loss after the rst cycle of chemotherapy (3wks post treatment). The't' test showed a signicant decrease in TSF [t=5.1(p<0.01)] and MAC [t=7.02 (p<0.01)] before and after 3 weeks of chemotherapy. The't' test showed a decrease in MAMC, t=5.78(p<0.01) before and after 3 weeks of chemotherapy. The mean serum Albumin level of the patients before and after 3weeks of chemotherapy was 3.27±.20 g/dl and 2.87±.62 g/dl respectively. A signicant decrease in albumin [t=3.97 at p<0.01 level] was observed in patients after chemotherapy. The mean haemoglobin level of the patients before and after 3weeks of chemotherapy was10.64±1.88 g/dl and10.41 ± 1.89 g/dl respectively, which showed a signicant decrease [(t=12.92 at p<0.01 level)]. Conclusion: The nutritional status assessment must be carried out on each patient at the beginning and during the treatment. The cancer patients who are receiving chemotherapy are at risk of malnutrition.


Nutrients ◽  
2019 ◽  
Vol 11 (3) ◽  
pp. 582 ◽  
Author(s):  
Irene Rodríguez-Gómez ◽  
Asier Mañas ◽  
José Losa-Reyna ◽  
Leocadio Rodríguez-Mañas ◽  
Sebastien Chastin ◽  
...  

The aim of this study was to determine the relationship between bone mass (BM) and physical activity (PA) and sedentary behavior (SB) according to frailty status and sex using compositional data analysis. We analyzed 871 older people with an adequate nutritional status. Fried criteria were used to classify by frailty status. Time spent in SB, light intensity PA (LPA) and moderate-to-vigorous intensity PA (MVPA) was assessed from accelerometry for 7 days. BM was determined by dual-energy X-ray absorptiometry (DXA). The combined effect of PA and SB was significantly associated with BM in robust men and women (p ≤ 0.05). In relation to the other behaviors, SB was negatively associated with BM in robust men while BM was positively associated with SB and negatively with LPA and MVPA in robust women. Moreover, LPA also was positively associated with arm BM (p ≤ 0.01). Finally, in pre-frail women, BM was positively associated with MVPA. In our sample, to decrease SB could be a good strategy to improve BM in robust men. In contrast, in pre-frail women, MVPA may be an important factor to consider regarding bone health.


2006 ◽  
Vol 7 (1) ◽  
pp. 58-70
Author(s):  
Ila Fadila

The study was conducted to explore the relationship between anthropometric measurement, i.e. skinfold thickness and cholesterol consentration in adult male and female blood. Other variables assumed as confounders including respondent characters namely: age, sex, ethnic, smoking habit, and activity. Analysis was done to a data from Health and Nutrition Survey on Adult on six cities in Indonesia. Prediction model of serum cholesterol with nutritional status assessment was developed by multiple regression analysis. Backward elimination procedure was used for model processing. The study result indicated that there was positive correlation between cholesterol and skinfold, age, and ethnic. Prediction model of serum cholesterol can be showed:  Serum Cholesterol  = 153,58 + 0,36 Skinfold + 0,34 age – 1,46 Sex – 48,71 Activity + 27,84 Ethnic


2014 ◽  
Vol 14 (63) ◽  
pp. 8821-8836
Author(s):  
SS Klobodu ◽  
◽  
M Steiner-Asiedu ◽  
E Colecraft ◽  
AK Anderson ◽  
...  

Alcoholism is a common problem in developing countries. Epidemiological studies on the relationship among excessive alcohol consumption, malnutrition and anaemia are inconclusive. The present study examined the association between alcohol intake and nutritional status of alcoholics in the Greater Accra Region of Ghana. The study was cross-sectional involving 107 participants (men and women) aged between 20 and 76 years. Participants were identified as alcoholics after screening with a combined, but modified CAGE and AUDIT questionnaires. Anthropometric data including weight, biceps skinfold thickness, triceps skinfold thickness, hip circumference and waist circumference were collected. Body mass index (BMI) and Waist-to-hip ratio were computed using appropriate measures. Haemoglobin levels of participants were also assessed. Dietary intakes of respondents were estimated by 24-hour recall which was further converted into nutrients and energy using ESHA food processor. A pretested questionnaire was also used to obtain data on sociodemographic and lifestyle characteristics of participants. Differences between participants based on level of alcohol intake and correlations among variables were tested for statistical significance using ANOVA and correlation analyses, respectively. Logistic regression was performed to examine the relationship between levels of total ethanol intake and overweight and obesity factors while controlling for age, smoking status, physical activity and total energy intake. There was an inverse correlation between triceps skinfold and level of alcohol consumption irrespective of predominant type of alcoholic beverage consumed (r= -0.213, P= 0.028). Further, there was a positive correlation between alcohol consumption and hip circumference among predominant beer consumers (r= 0.585, P= 0.046). A strong positive correlation was observed between alcohol intake and haemoglobin concentration for women (r= 0.729, P= 0.040) but not among men (r= -0.053, P= 0.722). Predominant beer consumers tend to have higher weight and BMI. Moderate level of total ethanol intake was associated with greater odds of being overweight/obese, whereas high levels of intake was associated with lower odds of being overweight/obesity although these were not statistically significant. The mechanisms for the observation of higher weight, BMI and hip circumference among predominant beer consumers in this population need further exploration.


PEDIATRICS ◽  
1971 ◽  
Vol 47 (3) ◽  
pp. 633-633
Author(s):  
S. P. Gupte

May I support the opinion expressed by Dr. Keet, et al.1 concerning the value of skinfold measurement in the assessment of nutritional status. Our own observations regarding detailed anthropometry on infants and children with advanced protein-calorie malnutrition are reported elsewhere.2,3 Triceps skinfold thickness in our cases of nutritional marasmus is consistently far below the 3rd percentile, the average being 3.2 ± 0.83 mm, which is about 40% of the Western standard. In kwashiorkor, on the other hand, it measures 6.5 ± 1.06 mm which is about 68.1% of the Western standard.


1998 ◽  
Vol 19 (4) ◽  
pp. 321-333 ◽  
Author(s):  
Detty Siti Nurdiati ◽  
Mohammad Hakimi ◽  
Abdul Wahab ◽  
Anna Winkvist

There are few studies on the nutritional status of nonpregnant women. A population-based, cross-sectional study of nutritional status in 5,817 non-pregnant women 15 to 49 years of age was conducted in Purworejo District, Indonesia, in 1996. Weight, height, mid-upper-arm circumference (MUAC), and triceps skinfold thickness were measured, and information on socio-economic, demographic, and reproductive factors was collected. Seventeen percent of the women had chronic energy deficiency and 11% were obese. Mean weight, MUAC, and triceps skinfold thickness corresponded to the 25th percentile of standards and mean height to the 5th percentile. Obesity was more common among older women and chronic energy deficiency among both the oldest and the youngest women. Women working in agriculture, not using contraceptives, and not owning a television, radio, or refrigerator were more likely to have chronic energy deficiency. In summary, both chronic energy deficiency and obesity existed in Purworejo, and risk factors were identified. Interventions are needed to improve the nutritional status of girls and women before and after pregnancy.


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