Acoustic Vibration Approach for Detecting Faults in Hydroelectric Units: A Review

The health of the hydroelectric generator determines the safe, stable, and reliable operation of the hydropower station. In order to keep the hydroelectric generator in a better state of health and avoid accidents, it is crucial to detect its faults. In recent years, fault detection methods based on sound and vibration signals have gradually become research hotspots due to their high sensitivity, achievable continuous dynamic monitoring, and easy adaptation to complex environments. Therefore, this paper is a supplement to the existing state monitoring and fault diagnosis system of the hydroelectric generator; it divides the hydroelectric generator into two significant parts: hydro-generator and hydro-turbine, and summarizes the research and application of fault detect technology based on sound signal vibration in hydroelectric generator and introduces some new technology developments in recent years, and puts forward the existing problems in the current research and future development directions, and it is expected to provides some reference for the research on fault diagnosis of the hydroelectric generator.

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Recent Advances and Perspectives of Molecularly Imprinted Polymer-Based Fluorescent Sensors in Food and Environment Analysis

Nanomaterials ◽

10.3390/nano9071030 ◽

2019 ◽

Vol 9 (7) ◽

pp. 1030 ◽

Cited By ~ 7

Author(s):

Guangyang Liu ◽

Xiaodong Huang ◽

Lingyun Li ◽

Xiaomin Xu ◽

Yanguo Zhang ◽

...

Keyword(s):

Molecularly Imprinted Polymer ◽

New Technology ◽

Three Dimensional ◽

High Sensitivity ◽

Detection Methods ◽

Fluorescent Nanoparticles ◽

Imprinted Polymer ◽

Recognition Mechanism ◽

Molecularly Imprinted ◽

Wide Range

Molecular imprinting technology (MIT), also known as molecular template technology, is a new technology involving material chemistry, polymer chemistry, biochemistry, and other multi-disciplinary approaches. This technology is used to realize the unique recognition ability of three-dimensional crosslinked polymers, called the molecularly imprinted polymers (MIPs). MIPs demonstrate a wide range of applicability, good plasticity, stability, and high selectivity, and their internal recognition sites can be selectively combined with template molecules to achieve selective recognition. A molecularly imprinted fluorescence sensor (MIFs) incorporates fluorescent materials (fluorescein or fluorescent nanoparticles) into a molecularly imprinted polymer synthesis system and transforms the binding sites between target molecules and molecularly imprinted materials into readable fluorescence signals. This sensor demonstrates the advantages of high sensitivity and selectivity of fluorescence detection. Molecularly imprinted materials demonstrate considerable research significance and broad application prospects. They are a research hotspot in the field of food and environment safety sensing analysis. In this study, the progress in the construction and application of MIFs was reviewed with emphasis on the preparation principle, detection methods, and molecular recognition mechanism. The applications of MIFs in food and environment safety detection in recent years were summarized, and the research trends and development prospects of MIFs were discussed.

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RECENT TRENDS IN DENGUE DETECTION METHODS USING BIOSENSORS

IIUM Engineering Journal ◽

10.31436/iiumej.v19i2.931 ◽

2018 ◽

Vol 19 (2) ◽

pp. 134-153 ◽

Cited By ~ 2

Author(s):

AHMAD ANWAR ZAINUDDIN ◽

ANIS NURASHIKIN NORDIN ◽

ROSMINAZUIN AB RAHIM

Keyword(s):

Low Cost ◽

New Technology ◽

High Sensitivity ◽

Hemorrhagic Fever ◽

Laboratory Diagnosis ◽

Optical Biosensor ◽

Ease Of Use ◽

Detection Methods ◽

Rt Pcr ◽

Minimal Sample

ABSTRACT: Dengue illness is an infectious tropical disease, transmitted by Aedes mosquitos, that poses a serious health threat to the tropical world. This disease causes widespread infection worldwide, with about 50 million cases of dengue occurring per annum out of which 500,000 recorded cases of dengue hemorrhagic fever and 22,000 deaths. Currently, there are no effective vaccines available to prevent the spread of the infection. Accurate and rapid laboratory diagnostic tests are required for early detection to reduce patient mortality rate. In this paper, common laboratory diagnosis methods for detecting dengue virus infection are discussed. Currently, virus isolation, RT-PCR and serology methods provide the most direct and accurate response for detection of dengue. However, these methods require tedious steps, expensive requirements and expert staffs. Recent research have proposed the usage of biosensors as an alternative new technology for detection of dengue. In this work, various types of biosensors such as electrochemical, piezoelectric, and optical biosensor have been described and compared to evaluate their effectiveness in dengue detection. It is observed that the optical biosensor offers the best detection due to its high sensitivity as compared to others, although it is popularly known as an expensive method. Alternatively, the use of electrochemical and piezoelectric biosensors (QCM) is highly recommended for detection of dengue due to their ease-of-use, low cost, low reagent consumption, disposability, and minimal sample preparation. These approaches have the potential to improve the rate of survival, particularly in resource-limited countries. ABSTRAK: Virus denggi adalah penyakit berjangkit tropika bawaan nyamuk Aedes yang menimbulkan ancaman serius kepada kesihatan global. Penyakit ini menyebabkan jangkitan yang meluas di seluruh dunia, dengan kira-kira 50 juta kes denggi yang berlaku setiap tahun di mana 500,000 kes demam denggi berdarah dan 22,000 kematian direkodkan. Buat masa ini, tiada vaksin yang berkesan untuk mencegah penyebaran jangkitan ini. Ujian diagnostik makmal yang cepat dan tepat diperlukan untuk pengesanan denggi awal untuk mengurangkan kadar kematian pesakit. Dalam artikel ini, kaedah diagnosis makmal yang biasa dilakukan untuk mengesahkan jangkitan virus denggi akan dibincangkan. Pada masa kini, kaedah pengasingan virus, RT-PCR dan serologi adalah tindak balas yang paling cepat dan tepat untuk mengesan denggi. Walau bagaimanapun, kaedah-kaedah ini memerlukan langkah-langkah yang melecehkan, kos penyelenggaraan yang tinggi dan kakitangan yang terlatih. Penyelidikan terkini telah mencadangkan penggunaan biosensor sebagai teknologi baru alternatif untuk mengesan denggi. Dalam artikel ini juga pelbagai jenis biosensor seperti biosensor elektrokimia, piezoelektrik, dan biosensor optik telah dijelaskan dan dibandingkan untuk menilai keberkesanannya dalam pengesanan denggi. Difahamkan bahawa biosensor optik menawarkan pengesanan terbaik kerana kepekaannya yang tinggi berbanding dengan yang lain, walaupun ia dikenali sebagai kaedah berkos tinggi. Sebaliknya, biosensor elektrokimia dan piezoelektrik (QCM) sangat disyorkan untuk mengesan denggi kerana ia mudah digunakan, berkos rendah, penggunaan bahan uji yang terhad, boleh dipakai buang, dan mempunyai penyediaan sampel yang minima. Pendekatan-pendekatan ini berpotensi untuk meningkatkan kadar kemandirian di kawasan-kawasan sumber terhad.

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Gold Immunochromatography Assay - A Newly Rapid Detection Technique for Aquatic Products

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.690-693.1449 ◽

2013 ◽

Vol 690-693 ◽

pp. 1449-1454

Author(s):

Yuan Wang ◽

Hui Juan Yu ◽

Bei Lei Qian ◽

You Qiong Cai ◽

Dong Mei Huang ◽

...

Keyword(s):

Rapid Detection ◽

High Sensitivity ◽

Detection Technique ◽

Detection Methods ◽

Future Perspectives ◽

Auxiliary Equipment ◽

Basic Principles ◽

Aquatic Products ◽

Immunological Detection

Gold immunochromatography assay (GICA) technique has the following characteristics: rapid and simple, high sensitivity, good specificity, no auxiliary equipment, ease of interpreting results, and satisfactory stability. The technique has become one of the most rapid and sensitive immunological detection methods, which is widely used in medical, biological and other fields. The article focuses on the basic principles and technical characteristics of GICA, and briefly describes the applications and future perspectives in the rapid detection of aquatic products.

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A rapid and accurate method for screening T-2 toxin in food and feed using competitive AlphaLISA

FEMS Microbiology Letters ◽

10.1093/femsle/fnab029 ◽

2021 ◽

Vol 368 (6) ◽

Author(s):

Liwen Zhang ◽

Qingyu Lv ◽

Yuling Zheng ◽

Xuan Chen ◽

Decong Kong ◽

...

Keyword(s):

High Sensitivity ◽

Accurate Method ◽

Detection Methods ◽

Cereal Crops ◽

Detection Range ◽

Highly Sensitive ◽

Food And Feed ◽

Good Repeatability ◽

Feed Samples ◽

Better Than

ABSTRACT T-2 is a common mycotoxin contaminating cereal crops. Chronic consumption of food contaminated with T-2 toxin can lead to death, so simple and accurate detection methods in food and feed are necessary. In this paper, we establish a highly sensitive and accurate method for detecting T-2 toxin using AlphaLISA. The system consists of acceptor beads labeled with T-2-bovine serum albumin (BSA), streptavidin-labeled donor beads and biotinylated T-2 antibodies. T-2 in the sample matrix competes with T-2-BSA for antibodies. Adding biotinylated antibodies to the test well followed by T-2 and T-2-BSA acceptor beads yielded a detection range of 0.03–500 ng/mL. The half-maximal inhibitory concentration was 2.28 ng/mL and the coefficient of variation was <10%. In addition, this method had no cross-reaction with other related mycotoxins. This optimized method for extracting T-2 from food and feed samples achieved a recovery rate of approximately 90% in T-2 concentrations as low as 1 ng/mL, better than the performance of a commercial ELISA kit. This competitive AlphaLISA method offers high sensitivity, good specificity, good repeatability and simple operation for detecting T-2 toxin in food and feed.

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Study on Detection Methods for Chlorine Precipitation during Biomass and Coal Co-Combustion

Applied Mechanics and Materials ◽

10.4028/www.scientific.net/amm.229-231.1423 ◽

2012 ◽

Vol 229-231 ◽

pp. 1423-1426

Author(s):

Yong Zheng Wang ◽

Lei Jiang ◽

Mao Zhen Yue ◽

Su Fang Bian

Keyword(s):

Silver Nitrate ◽

Lower Limit ◽

Spectrophotometric Method ◽

Flue Gas ◽

High Sensitivity ◽

Volumetric Analysis ◽

Sample Solution ◽

Detection Methods ◽

Multiple Measurements ◽

Blend Fuel

In this paper, three detection methods were analyzed to determine the chlorine precipitation from the flue gas: Silver nitrate volumetric analysis (SNVA), Volhard method (VM) and Mercuric thiocyanate spectrophotometric method (MTSM). Results indicated that SNVA and VM were simple and convenient, but unsuitable for the detection of blend fuel due to the high lower limit. MTSM was suitable for biomass and coal co-combustion for its low lower limit and high sensitivity. In addition, MTSM needed less sample solution, which made it more suitable for multiple measurements to reduce errors, and the maximum proportional error was only 3.5%.

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On site investigation and continuous dynamic monitoring of a historic tower in Mantua, Italy

Emerging Technologies in Non-Destructive Testing VI ◽

10.1201/b19381-80 ◽

2015 ◽

pp. 485-492 ◽

Cited By ~ 1

Author(s):

A Saisi ◽

M Guidobaldi ◽

C Gentile

Keyword(s):

Site Investigation ◽

Dynamic Monitoring ◽

Continuous Dynamic Monitoring ◽

Continuous Dynamic

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CircRNAs and their regulatory roles in cancers

Molecular Medicine ◽

10.1186/s10020-021-00359-3 ◽

2021 ◽

Vol 27 (1) ◽

Author(s):

Mei Tao ◽

Ming Zheng ◽

Yanhua Xu ◽

Shuo Ma ◽

Weiwei Zhang ◽

...

Keyword(s):

Nuclear Export ◽

Mrna Translation ◽

High Sensitivity ◽

Detection Methods ◽

Circular Rnas ◽

Rnase L ◽

Circular Structure ◽

Dynamic Modification ◽

Non Coding Rnas

AbstractCircular RNAs (circRNAs), a novel type of non-coding RNAs (ncRNAs), have a covalently closed circular structure resulting from pre-mRNA back splicing via spliceosome and ribozymes. They can be classified differently in accordance with different criteria. As circRNAs are abundant, conserved, and stable, they can be used as diagnostic markers in various diseases and targets to develop new therapies. There are various functions of circRNAs, including sponge for miR/proteins, role of scaffolds, templates for translation, and regulators of mRNA translation and stability. Without m7G cap and poly-A tail, circRNAs can still be degraded in several ways, including RNase L, Ago-dependent, and Ago-independent degradation. Increasing evidence indicates that circRNAs can be modified by N-6 methylation (m6A) in many aspects such as biogenesis, nuclear export, translation, and degradation. In addition, they have been proved to play a regulatory role in the progression of various cancers. Recently, methods of detecting circRNAs with high sensitivity and specificity have also been reported. This review presents a detailed overview of circRNAs regarding biogenesis, biomarker, functions, degradation, and dynamic modification as well as their regulatory roles in various cancers. It’s particularly summarized in detail in the biogenesis of circRNAs, regulation of circRNAs by m6A modification and mechanisms by which circRNAs affect tumor progression respectively. Moreover, existing circRNA detection methods and their characteristics are also mentioned.

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Recent advances in fecal gene detection for colorectal cancer diagnosis

Biomarkers in Medicine ◽

10.2217/bmm-2021-0269 ◽

2021 ◽

Vol 15 (14) ◽

pp. 1299-1308

Author(s):

Siyu He ◽

Chenglin Zhou ◽

Hailin Peng ◽

Mei Lin

Keyword(s):

Colorectal Cancer ◽

Cancer Diagnosis ◽

Gradual Increase ◽

Dynamic Monitoring ◽

Gene Detection ◽

Crc Screening ◽

Prognostic Assessment ◽

Advanced Stages ◽

Continuous Dynamic Monitoring ◽

Continuous Dynamic

There has been a gradual increase in the incidence of colorectal cancer (CRC) in recent years. Most patients lack obvious early symptoms, but are commonly in mid and advanced stages when the symptoms become evident, with rather high mortalities. Early diagnosis, treatment and recurrence monitoring are crucial to improving the recovery rate of CRC. Studies have shown that tumor-related genes can be detected in the feces of CRC patients. Owing to non-invasiveness, convenient sampling and continuous dynamic monitoring, fecal gene detection may be applicable to CRC screening, diagnosis, prognostic assessment and recurrence monitoring. Herein, we review the research advances in fecal gene detection for CRC diagnosis.

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