scholarly journals Utilization of Grape Seed Extract as a Natural Antioxidant in the Technology of Meat Products Inoculated with a Probiotic Strain of LAB

Foods ◽  
2020 ◽  
Vol 9 (1) ◽  
pp. 103 ◽  
Author(s):  
Justyna Libera ◽  
Agnieszka Latoch ◽  
Karolina Maria Wójciak
Keyword(s):  
Lactic Acid ◽  
Oleic Acid ◽  
Lactic Acid Bacteria ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract ◽  
Natural Antioxidant ◽  
Sodium Ascorbate ◽  
Grape Seeds ◽  
Food Ingredients

Grape seeds have been evaluated for use as food ingredients with stabilizing effects in meat technology. A pork neck, inoculated with probiotic monoculture (Lactobacillus rhamnosus LOCK900), was used as the matrix. The study compared the antioxidant potential of grape seed extract to sodium ascorbate. Three experimental variants of the products were prepared: With grape seed extract, with sodium ascorbate, and without additives. The meat ripened for two months, and during this period of time biophysicochemical analyses (product color, pH, number of lactic acid bacteria, content of free fatty acids, and thiobarbituric acid reactive substances) were carried out. It was found that the extract inhibited lipid hydrolysis occurring in the neck (1% of oleic acid) and limited oxidative processes (0.46 mg MDA kg−1), with efficacy similar to that of sodium ascorbate (0.9% of oleic acid and 0.53 mg MDA kg−1, respectively). No limitation of the desired lactic acid bacteria growth (approximately 7 log cfu g−1) was noticed in the meat samples with the extract. The results are optimistic because they indicate that not only is it possible to produce fermented pork neck inoculated with probiotic, but there are also no obstacles to utilizing grape seed extract as a natural antioxidant in this technology.

Grape Seeds Extract as Brain Food: A Review

2017 ◽  
Vol 9 (1) ◽  
Author(s):  
Souad El Gengaihi ◽  
Doha H. Abou Baker
Keyword(s):  
Antioxidant Activities ◽  
Complex Mixture ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract ◽  
Amyloid Peptide ◽  
Grape Seeds ◽  
Potential Benefits ◽  
Reduced Risk

Interest in the biological role of bioactive compounds present in medicinal herbs has increased over the last years. Of particular interest are plants that have an anti-Alzheimer activities. Several plants can be useful for Alzheimer (AD) management. Such as these which have anti-inflammatory activity, acetylcholinesterase (AChE) inhibitory action, antiapoptotic, slow the aggregation of amyloid peptide and antioxidant activities. Grape seed extract (GSE) is a complex mixture of several compounds, mostly represented by polyphenols and flavonoids. Their consumption is safe and is recognized to exert several health benefits. GS flavonoids have been associated with the reduced risk of chronic diseases, we present some findings on the potential benefits of GSE for the treatment of AD.

scholarly journals Comparative Evaluation of Immediate Bond Strength to Bleached Enamel Following Application of Various Antioxidant Solutions

2017 ◽  
Vol 05 (02) ◽  
pp. 084-089
Author(s):  
Alisha Dhingra ◽  
Ashu Gupta ◽  
Anshu Minocha ◽  
Nayantara Sen
Keyword(s):  
Bond Strength ◽  
Shear Bond Strength ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract ◽  
The Other ◽  
Sodium Ascorbate ◽  
Group V ◽  
Group I ◽  
Significant Difference

Abstract Aim: The aim of this study was to compare the reversal of shear bond strength of composite to bleached enamel immediately after bleaching followed by application of various antioxidant solutions. Material and Methods: Seventy central incisors were divided into seven groups. Groups I and II served as unbleached and bleached controls respectively. Groups III, IV, V, VI and VII served as the experimental groups and were subjected to 37.5% hydrogen peroxide bleaching followed by 10 min application of 10% sodium ascorbate, 25% alpha-tocopherol, 6.5% grape seed extract, 5% lycopene and 5% green tea extract respectively. Following composite bonding, shear bond strength was determined and the results were analyzed using ANOVA followed by Post Hoc Multiple Comparisons test. Results: The bond strength values for Group I (positive control) were maximum and significantly different than all the other groups except Grape seed extract group (Group V). When compared to Group II (bleached control), all the groups showed significantly higher bond strength. Significant difference in the bond strength values were seen between Group III (10% sodium ascorbate) and Group V. Also values for Group V were significantly different from Group VI (5% lycopene). All the other values showed insignificantly different results. Conclusion: All the antioxidant solutions improved the shear bond strength values after bleaching but only Grape seed extract application reversed the values to the non bleached levels. Lycopene was least effective. Other antioxidants showed comparable results.

scholarly journals A study on antibacterial effect of grape seed extracts in common clinical and drug resistant isolates

2016 ◽  
Vol 3 (3) ◽  
pp. 165
Author(s):  
Mohanakrishnan Kandasamy ◽  
Sowmya Nasimuddin ◽  
Jeevan Malayan ◽  
Nithyalakshmi J ◽  
Sumathi Gnanadesikan ◽  
...  
Keyword(s):  
Antibacterial Effect ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract ◽  
Clinical Isolates ◽  
Drug Resistant ◽  
Grape Seeds ◽  
Mrsa Strains ◽  
Agar Well Diffusion Assay ◽  
Grape Seed Extracts

<p class="abstract"><strong>Background:</strong> Grape seeds are proposed to have antimicrobial activity, antioxidant effect and various other benefits to mankind. A study was done to assess the antibacterial effect of grape seed extract against common clinical isolates and drug resistant pathogenic strains.</p><p class="abstract"><strong>Methods:</strong> Grape seed extract prepared was investigated for its antibacterial effect against 65 bacterial isolates obtained from clinical specimens by agar well diffusion assay and the results were compared with routinely used antibiotics namely, Gentamicin for the common clinical isolates, Vancomycin for MRSA strains and Amikacin for ESBL organisms respectively.</p><p class="abstract"><strong>Results:</strong> Grape seed extract produced moderate zone of inhibition ranging between 11-15 mm among the 35 test common clinical isolates namely <em>Staphylococcus aureus, Escherichia coli, Klebsiella </em>sp<em> </em>and<em> Pseudomonas aeruginosa</em>.  <em>E.coli </em>showed the highest susceptibility with zone ranging from 12-14 mm with increasing concentration of the extract starting from2 mg/ml to the highest being 20 mg/ml. Among the 30 drug resistant pathogenic strains like MRSA and ESBL producing organisms, the grape seed extract was found to be effective against 3 out of the 10 of MRSA and 2 out of the 10 of ESBL-<em>E.coli</em> at the highest concentration of 20 mg/ml. However, ESBL producing <em>Klebsiella </em>species were found to be resistant even to the highest concentration of the extract.  </p><p><strong>Conclusions:</strong> The results provide evidence that the grape seed extract could be a potential antibacterial agent and this effect can further be made evident with improved methodologies.</p>

scholarly journals Effects of Polyphenols from Grape Seeds on Renal Lithiasis

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Felix Grases ◽  
Rafel M. Prieto ◽  
Rafel A. Fernandez-Cabot ◽  
Antonia Costa-Bauzá ◽  
Fernando Tur ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Calcium Oxalate ◽  
Complex Disease ◽  
Urine Analysis ◽  
Calcium Oxalate Monohydrate ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Oxidative Capacity ◽  
Seed Extract ◽  
Grape Seeds

Nephrolithiasis is a complex disease that results from a combination of factors related to both urine composition and kidney morphoanatomy. Development of calcium oxalate monohydrate papillary calculi is linked to initial subepithelial calcification of renal papilla. Progressive tissue calcification depends on preexisting injury and involves reactive oxygen species. Many plant extracts that protect against oxidative stress manifest antilithiasic activity. Our study focused on determining the effects of polyphenols on a lithiasis rat model. Rats were pretreated with polyphenols and grape seed extracts, followed by posterior induction of hyperoxalosis via treatment with ethylene glycol plus NH4Cl. The concentrations of calcium and other elements in kidney were determined, along with histological examination of kidney and 24 h urine analysis. Significant differences were observed in the renal calcium content between the control plus ethylene glycol-treated group and the epicatechin plus ethylene glycol-treated, red grape seed extract plus ethylene glycol-treated, and white grape seed extract plus ethylene glycol-treated groups, with reductions of about 50%. The antioxidant activity of polyphenols extracted from red and white grape seeds may be critical in the prevention of calcium oxalate monohydrate papillary calculus formation, particularly if calculi are induced by lesions caused by cytotoxic compounds with oxidative capacity.

scholarly journals Dual Anticoagulant/Antiplatelet Activity of Polyphenolic Grape Seeds Extract

Nutrients ◽  
2019 ◽  
Vol 11 (1) ◽  
pp. 93 ◽  
Author(s):  
Michal Bijak ◽  
Agnieszka Sut ◽  
Anna Kosiorek ◽  
Joanna Saluk-Bijak ◽  
Jacek Golanski
Keyword(s):  
Blood Platelets ◽  
Adenosine Diphosphate ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Potential Effect ◽  
In Vitro Models ◽  
Seed Extract ◽  
Grape Seeds ◽  
Induced Aggregation

Because of the side-effects of commonly used anti-platelet and anticoagulant drugs, investigations into plant substances with similar activities are very common. Based on our own studies in recent years, we estimate that it is possible to use natural compounds to both inhibit coagulation pathway enzymes and to reduce blood platelets’ activation. As such, in our current study we wanted to verify the anti-platelet and anticoagulant properties of grape seed extract (GSE) using in vitro models. During our analysis, the following parameters were analyzed: Coagulation times, thromboelastometry assays (coagulation time, clot formation time and maximum clot firmness), aggregation of platelets and phosphorylation of vasodilator-stimulated phosphoprotein (VASP). Adenosine diphosphate (ADP)-induced aggregation was lower in GSE 7.5 µg/mL as well as in GSE 15.0 µg/mL. A similar dependence was observed in VASP assays for GSE 7.5 µg/mL and GSE 15 µg/mL. The effect on plasma coagulation tests was distinct only with GSE 15 µg/mL. All of the thromboelastometry variables were statistically significant with 15.0 µg/mL GSE concentration. Our results show, for the first time, the multi-potential effect of grape seed extract on coagulation systems, and clearly suggest that grape seed extract could be considered a promising nutraceutical in the prevention of cardiovascular thrombotic events caused by different mechanisms.

scholarly journals Effect of Adding Different Levels of Grapes (Vitis vinifera L.) Seeds and Leaf Powder or their Extracts on Some Bone Characteristics and Total Ash Content in Broiler Chickens

2021 ◽  
Author(s):  
Rabia J. Abbas ◽  
Taha Hasheem Khauoon
Keyword(s):  
Broiler Chickens ◽  
Leaf Extract ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract ◽  
Ash Content ◽  
Vitis Vinifera L ◽  
Grape Seeds ◽  
Leaf Powder ◽  
Grape Leaf

Background: Some natural sources of polyphenols like grape seed, leaf or extracts, have many benefits in maintaining bone health in animals. This study aimed to investigate the efficacy of grape seeds, grape leaves powder, or their extracts on some bone characteristics and total ash content in broiler chickens. Methods: Three hundred and twenty four one-day-old broilers were allocated to nine treatments with three replicates containing 12 chicks each. Chicks were fed nine experimental diets for 35 days; as a control diet without supplementation (T1), control diets supplemented with 15 and 30 g/kg grape seeds powder (GSP) (T2, T3), 15 and 30 g/kg grape leaf powder (GLP) (T4, T5), grape seed extract (GSE) at levels 2 and 4 ml/l added in drinking water (T6, T7) and with grape leaf extract (GLE ) at levels 2 and 4 ml/l (T8 and T9), respectively. Result: Significant increase (p≤0.05) in the bone length was recorded with GSP (30 g/kg), GLP (15 g/kg), GSE or GLE and calcium percent with GLE as compared with control. Furthermore, significant improvement was recorded in predictive skeletal weight of broilers fed GSE (T6 α T7) as compared to the other treatments. The study concluded that the best results were achieved at the 2 or 4 ml/l of grape seed extract in improving femur length, predicted skeletal weight and from grape leaf extract in improving calcium percentage in broiler bone ash.

scholarly journals Antioxidant/Prooxidant and Antibacterial/Probacterial Effects of a Grape Seed Extract in Complex with Lipoxygenase

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Veronica Sanda Chedea ◽  
Cornelia Braicu ◽  
Flore Chirilă ◽  
Henry Joseph Oduor Ogola ◽  
Rodica Ştefania Pelmuş ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Control Level ◽  
Grape Seed Extract ◽  
Grape Seed ◽  
Seed Extract ◽  
Grape Seeds ◽  
E Coli ◽  
Prooxidant Action ◽  
High Level ◽  
Short Time

In an attempt to determine the antioxidant/prooxidant, antibacterial/probacterial action of flavan-3-ols and procyanidins from grape seeds, pure catechin (CS), and an aqueous grape seed extract (PE), were applied in the absence and presence of pure lipoxygenase (LS) or in extract (LE) to leucocyte culture,Escherichia coli B41andBrevibacterium linens, and observed whether there was any effect on lipid peroxidation, cytotoxicity, or growth rate. Short time periods of coincubation of cells with the polyphenols, followed by the exposure to LS and LE, revealed a high level of lipid peroxidation and a prooxidative effect. Longer coincubation and addition of LS and LE resulted in the reversal of the prooxidant action either to antioxidant activity for CS + LS and PE + LS or to the control level for CS + LE and PE + LE. Lipid peroxidation was significantly reduced when cells were exposed to polyphenols over a longer period. Longer exposure ofE. colito CS or PE followed by addition of LS for 3 h resulted in bactericidal activity. Significant stimulatory effect on microbial growth was observed for PE + LS and PE + LE treatments inB. linens, illustrating the potential probacterial activity inB. linenscultures. Lipoxygenase-polyphenols complex formation was found to be responsible for the observed effects.

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