scholarly journals A Comparative Study of the Bioavailability of Fe, Cu and Zn from Gluten-Free Breads Enriched with Natural and Synthetic Additives

Foods ◽  
2020 ◽  
Vol 9 (12) ◽  
pp. 1853
Author(s):  
Anna Rogaska ◽  
Julita Reguła ◽  
Joanna Suliburska ◽  
Zbigniew Krejpcio

The aim of this study was to compare the bioavailability of iron, copper and zinc from newly designed gluten-free breads enriched with natural and synthetic additives. The study was conducted on rats with induced Fe, Cu and Zn deficiency. The nutritional intervention with diets supplemented with a 70% addition of gluten-free breads enriched with natural additives and organic compounds to the control diet AIN-93M lasted 40 days. After the intervention, the rats were euthanized, the organs were collected and their mineral content was measured. Chemical analysis of diets with the addition of fortified gluten-free breads showed significantly higher amounts of iron, zinc and copper in diets with the addition of fortified breads compared to diets with the addition of unenriched breads. The type of additives did not influence the amount of minerals in diets. It is necessary to conduct further research to explain the interactions of ingredients and the factors affecting the bioavailability of Fe, Cu and Zn from gluten-free breads in order to obtain a product with a high bioavailability of these ingredients.

Author(s):  
Abera Admasu Birhanu ◽  
Bezuayehu Kerisew Semahagn ◽  
Endalkachew Nibret Simegn ◽  
Melaku Adal Eshetie ◽  
Abayneh Munshea Abitew

Aims: To evaluate serum copper (Cu) and zinc (Zn) concentration in relation to clinical status among people living with HIV/AIDS for possible interventions. Study Design: A cross-sectional study design was used. Place and Duration of Study: The study was conducted between January and February 2013 in Felege Hiwot Referral Hospital, Bahir Dar, Ethiopia. Methods: Serum concentrations of Cu and Zn from 150 people living with HIV/AIDS were measured using a fully automated flame atomic absorption spectrophotometer. Besides, world health organization (WHO) clinical staging, CD4+ T-cell count, CD8+ T-cell count, hemoglobin determination, and Body Mass Index (BMI) were performed to evaluate the clinical status of study participants. Results: Multivariate logistic regression analysis showed that being serum Zn and Cu deficient was higher where there is no antiretroviral therapy (ART) than on ART (adjusted odds ratio (AOR)=3.56, 95% confidence interval (CI)=1.52-8.33, P=0.003 and 5.85, 95% CI=1.22-28.058, P= 0.027respectively).Similarly, the odds of being serum Zn deficient were significantly associated to lower BMI than normal (AOR=2.61, 95% CI=1.02 - 6.67, P= 0.046) and abnormal hemoglobin was found to be a factor to having high serum Cu/Zn ratio than normal hemoglobin (AOR=3.26, 95% CI=1.07 - 9.94, P= 0.038). Conclusions: A relatively high percentage of subjects had serum Cu and Zn deficiency and high serum Cu/Zn ratio. Early evaluation of serum Cu and Zn deficiency should be carried out and mineral supplementation along with antiretroviral treatment should be provided for pre-ART, malnourished and anemic people living with HIV/AIDS.


1984 ◽  
Vol 52 (3) ◽  
pp. 545-560 ◽  
Author(s):  
R. Giugliano ◽  
D. J. Millward

1. Male weanling rats were fed on diets either adequate (55 mg/kg), or severely deficient (0.4 mg/kg) in zinc, either ad lib. or in restricted amounts in four experiments. Measurements were made of growth rates and Zn contents of muscle and several individual tissues.2. Zn-deficient rats exhibited the expected symptoms of deficiency including growth retardation, cyclic changes in food intake and body-weight.3. Zn deficiency specifically reduced whole body and muscle growth rates as indicated by the fact that (a) growth rates were lower in ad lib.-fed Zn-deficient rats compared with rats pair-fed on the control diet in two experiments, (b) Zn supplementation increased body-weights of Zn-deficient rats given a restricted amount of diet at a level at which they maintained weight if unsupplemented, (c) Zn supplementation maintained body-weights of Zn-deficient rats fed a restricted amount of diet at a level at which they lost weight if unsupplemented (d) since the ratio, muscle mass:body-weight was lower in the Zn-deficient rats than in the pair-fed control groups, the reduction in muscle mass was greater than the reduction in body-weight.4. Zn concentrations were maintained in muscle, spleen and thymus, reduced in comparison to some but not all control groups in liver, kidney, testis and intestine, and markedly reduced in plasma and bone. In plasma, Zn concentrations varied inversely with the rate of change of body-weight during the cyclic changes in body-weight.5. Calculation of the total Zn in the tissues examined showed a marked increase in muscle Zn with a similar loss from bone, indicating that Zn can be redistributed from bone to allow the growth of other tissues.6. The magnitude of the increase in muscle Zn in the severely Zn-deficient rat, together with the magnitude of the total losses of muscle tissue during the catabolic phases of the cycling, indicate that in the Zn-deficient rat Zn may be highly conserved in catabolic states.


Author(s):  
P. Ramamoorthy ◽  
P. Christy Nirmala Mary ◽  
P. Saravanapandian ◽  
A. Gurusamy ◽  
K. Kumutha

A soil resource inventory was conducted at village level in the Melur block of Madurai district, Tamil Nadu to assess the micronutrients status in the soils and to prepare fertility maps depicting the extent of soil micronutrient deficiency/sufficiency using GIS and GPS techniques. Soil samples were collected at revenue village wise along with geo coordinates and analysed for available micronutrients such as Zn, Fe, Cu and Mn by adopting standard procedures. Based on the nutrient status, the soils were grouped as deficient or sufficient using the critical limits. Per cent deficiency of micronutrients in Melur block was worked out and the thematic maps showing status of different available micronutrients were generated. The results indicated that, Fe and Zn  deficiency is most prevalent in the soils of Melur block  in Madurai district to an extent of more than 35 per cent, followed by Cu (1.1%) and Mn (10%).


2019 ◽  
Vol 13 (4) ◽  
pp. 66-74
Author(s):  
U. A. Yakubova ◽  
O. V. Bugrova ◽  
S. I. Krasikov ◽  
N. P. Setko ◽  
R. I. Saifutdirov

The role of trace elements (TEs) and their imbalance in the physiology of bone tissue and in the development of inflammatory diseases of the joints and spine has been discussed in recent years; however, there is no evidence for the TE status of patients with ankylosing spondylitis (AS) and its possible impact on the course of the disease.Objective: to investigate the impact of the TE status of patients with AS on the course, clinical manifestations, and activity of the disease.Patients and methods. Examinations were made in 58 patients (39 men and 19 women), residents of the Orenburg Region, with a reliable diagnosis of AS, the duration of which was 16 [11; 26] years. The patients’ mean age was 38 [31; 48] years. HLA-B27 antigen was detected in 91.4% of cases. In addition to the generally accepted examination, atomic absorption spectrophotometry was used to determine the hair levels of 9 TEs: Cu, Zn, Fe, Mn, Cr, Co, Ni, Pb, and Cd in all the patients.Results and discussion. The AS patients living in the Orenburg Region showed TE imbalance manifested by Cu and Zn deficiency and Ni, Cr, and Mn accumulation in the hair. Multidirectional correlations were found between the values of these TEs and the presence of extra-axial (peripheral arthritis, dactylitis) and extra-skeletal (uveitis) manifestations of AS, its activity, and severity of functional disorders.Conclusion. The preliminary results may suggest that the emerging imbalance of TEs can affect the course of AS, maintaining and increasing its activity.


1993 ◽  
Vol 57 (2) ◽  
pp. 224-228 ◽  
Author(s):  
S Mora ◽  
G Weber ◽  
G Barera ◽  
A Bellini ◽  
D Pasolini ◽  
...  

2008 ◽  
Vol 69 (2) ◽  
pp. 101-105 ◽  
Author(s):  
Gisèle Léger-Leblanc ◽  
France M. Rioux

Purpose: To evaluate initiation and duration of breastfeeding of infants born to mothers who participated in the Early Childhood Initiative (ECI) program. Factors affecting the initiation and the early cessation of breastfeeding were also explored. Methods: Twenty-five pregnant women participating in the ECI program completed this prospective study. At 36 weeks’ gestation, a questionnaire was administered to assess socioeconomic status, intention to breastfeed and breastfeeding experience. When the infants were three and six months of age, feeding practices were assessed with a questionnaire. Results: The breastfeeding initiation rate was 62.5%. At one and three months postpartum, exclusive breastfeeding rates were 39% and 4%, respectively. At six months, none of the women was exclusively breastfeeding. Primiparity, prenatal classes, having been breastfed and intention to breastfeed at 36 weeks’ gestation were positively associated with breastfeeding initiation. Father’s education, intention to breastfeed at 36 weeks’ gestation, no water or formula given to the infant during hospitalization and higher maternal hemoglobin level at 36 weeks’ gestation were positively associated with the duration of breastfeeding. Conclusions: The rate of initiation and duration of breastfeeding for ECI participants were low. To achieve successful interventions, it is important to target modifiable factors known to influence the initiation and duration of breastfeeding within this population.


1999 ◽  
Vol 79 (3) ◽  
pp. 405-408 ◽  
Author(s):  
J. M. Bell ◽  
G. Rakow ◽  
R. K. Downey

Three cultivars of Brassica (Westar, Brassica napus; Tobin, B. rapa; Cutlass, B. juncea) were grown in four locations in 4 successive years, with duplicate samples taken from each treatment. Harvested seed was hexane-extracted, ground and analyzed for mineral content. The average contents (mg kg−1) were: Ca, 0.64; P, 1.12; Mg, 0.56%; Cu, 6.2; Zn, 46; Fe, 188; and Mn, 55. Values for Westar and Tobin were generally similar but Cutlass contained less Ca, Mg, Fe and Mn and more Cu and Zn (P < 0.01). Locations affected all mineral levels. One location produced samples lower in Ca, P, Cu and Mn but higher in Zn than the other locations (P < 0.01). Year-to-year variability was of minor consequence. Key words: Brassica napus, Brassica rapa, Brassica juncea, mineral, seed


1990 ◽  
Vol 114 (2) ◽  
pp. 133-138 ◽  
Author(s):  
C. L. Johnson ◽  
G. Powley

SUMMARYA balance experiment was carried out using four young lactating goats in a Latin square design, fed with perennial ryegrass (Lolium perenne) from plots that had received 377 kg K/ha (diet 1); 63 kg K plus 377 kg Na/ha (diet 2); 188 kg K plus 188 kg Na/ha (diet 3) or no fertilizer (control diet 4).The apparent availability of Mg was high in all the grass diets (0·355–0·469); it was significantly depressed (P < 0·05) when the intake of K was high (diet 1); but was not significantly different when a high intake of K was accompanied by a high intake of Na (diet 3).There was a significantly lower (P < 0·05) apparent availability of Na in diet 4 and a significantly higher (P < 0·05) apparent availability of K in diet 3. There were no significant differences in the apparent availability of Ca.The plasma Mg concentration was not significantly affected by any dietary treatment but did decrease temporarily when diets were changed.There were no significant effects on mineral concentrations in the milk.


1980 ◽  
Vol 43 (3) ◽  
pp. 551-559 ◽  
Author(s):  
Mary H Stevenson ◽  
N. Jackson

1. Cereal-based diets containing 0, 500, 1000 or 2000 mg added copper/kg were offered ad lib. to laying hens for 8 weeks. All the hens were subsequently offered the control diet (no added Cu, 7.5 mg Cu/kg).2. Hens from each treatment were killed at 0, 2, 4, 6 and 8 weeks after removal of the Cu-supplemented diets. Records were kept of body-weight, food consumption and egg production.3. After slaughter, blood haemoglobin, packed cell volume, serum Cu and aspartate aminotransferase (AAT; EC 2.6.1.1) were assayed. The liver, kidneys, oviduct, ovary, gizzard, caeca and bile duct were weighed.4. Mean Cu, zinc and iron concentration of liver, kidneys and caecal contents were determined.5. The adverse effects of Cu on body-weight, food intake, egg production and liver, oviduct, ovary, gizzard and bile weights were rapidly reversed by removal of added Cu from the diets.6. Greatly enhanced liver Cu concentration resulted from feeding the high-Cu diets but this effect was rapidly reversed on removal of added Cu from the diets. Liver Fe concentration showed a less marked but similar effect.7. The Cu concentration of caecal contents was increased by Cu supplementation and rapidly reduced after withdrawal of the Cu-containing diets.


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