scholarly journals pcPromoter-CNN: A CNN-Based Prediction and Classification of Promoters

Genes ◽  
2020 ◽  
Vol 11 (12) ◽  
pp. 1529
Author(s):  
Muhammad Shujaat ◽  
Abdul Wahab ◽  
Hilal Tayara ◽  
Kil To Chong

A promoter is a small region within the DNA structure that has an important role in initiating transcription of a specific gene in the genome. Different types of promoters are recognized by their different functions. Due to the importance of promoter functions, computational tools for the prediction and classification of a promoter are highly desired. Promoters resemble each other; therefore, their precise classification is an important challenge. In this study, we propose a convolutional neural network (CNN)-based tool, the pcPromoter-CNN, for application in the prediction of promotors and their classification into subclasses σ70, σ54, σ38, σ32, σ28 and σ24. This CNN-based tool uses a one-hot encoding scheme for promoter classification. The tools architecture was trained and tested on a benchmark dataset. To evaluate its classification performance, we used four evaluation metrics. The model exhibited notable improvement over that of existing state-of-the-art tools.

2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
Yizhe Wang ◽  
Cunqian Feng ◽  
Yongshun Zhang ◽  
Sisan He

Precession is a common micromotion form of space targets, introducing additional micro-Doppler (m-D) modulation into the radar echo. Effective classification of space targets is of great significance for further micromotion parameter extraction and identification. Feature extraction is a key step during the classification process, largely influencing the final classification performance. This paper presents two methods for classifying different types of space precession targets from the HRRPs. We first establish the precession model of space targets and analyze the scattering characteristics and then compute electromagnetic data of the cone target, cone-cylinder target, and cone-cylinder-flare target. Experimental results demonstrate that the support vector machine (SVM) using histograms of oriented gradient (HOG) features achieves a good result, whereas the deep convolutional neural network (DCNN) obtains a higher classification accuracy. DCNN combines the feature extractor and the classifier itself to automatically mine the high-level signatures of HRRPs through a training process. Besides, the efficiency of the two classification processes are compared using the same dataset.


2019 ◽  
Vol 14 (1) ◽  
pp. 124-134 ◽  
Author(s):  
Shuai Zhang ◽  
Yong Chen ◽  
Xiaoling Huang ◽  
Yishuai Cai

Online feedback is an effective way of communication between government departments and citizens. However, the daily high number of public feedbacks has increased the burden on government administrators. The deep learning method is good at automatically analyzing and extracting deep features of data, and then improving the accuracy of classification prediction. In this study, we aim to use the text classification model to achieve the automatic classification of public feedbacks to reduce the work pressure of administrator. In particular, a convolutional neural network model combined with word embedding and optimized by differential evolution algorithm is adopted. At the same time, we compared it with seven common text classification models, and the results show that the model we explored has good classification performance under different evaluation metrics, including accuracy, precision, recall, and F1-score.


2021 ◽  
Author(s):  
Anh Nguyen ◽  
Khoa Pham ◽  
Dat Ngo ◽  
Thanh Ngo ◽  
Lam Pham

This paper provides an analysis of state-of-the-art activation functions with respect to supervised classification of deep neural network. These activation functions comprise of Rectified Linear Units (ReLU), Exponential Linear Unit (ELU), Scaled Exponential Linear Unit (SELU), Gaussian Error Linear Unit (GELU), and the Inverse Square Root Linear Unit (ISRLU). To evaluate, experiments over two deep learning network architectures integrating these activation functions are conducted. The first model, basing on Multilayer Perceptron (MLP), is evaluated with MNIST dataset to perform these activation functions.Meanwhile, the second model, likely VGGish-based architecture, is applied for Acoustic Scene Classification (ASC) Task 1A in DCASE 2018 challenge, thus evaluate whether these activation functions work well in different datasets as well as different network architectures.


Author(s):  
Qi Xin ◽  
Shaohao Hu ◽  
Shuaiqi Liu ◽  
Ling Zhao ◽  
Shuihua Wang

As one of the important tools of epilepsy diagnosis, the electroencephalogram (EEG) is noninvasive and presents no traumatic injury to patients. It contains a lot of physiological and pathological information that is easy to obtain. The automatic classification of epileptic EEG is important in the diagnosis and therapeutic efficacy of epileptics. In this article, an explainable graph feature convolutional neural network named WTRPNet is proposed for epileptic EEG classification. Since WTRPNet is constructed by a recurrence plot in the wavelet domain, it can fully obtain the graph feature of the EEG signal, which is established by an explainable graph features extracted layer called WTRP block . The proposed method shows superior performance over state-of-the-art methods. Experimental results show that our algorithm has achieved an accuracy of 99.67% in classification of focal and nonfocal epileptic EEG, which proves the effectiveness of the classification and detection of epileptic EEG.


2021 ◽  
pp. 1-10
Author(s):  
Gayatri Pattnaik ◽  
Vimal K. Shrivastava ◽  
K. Parvathi

Pests are major threat to economic growth of a country. Application of pesticide is the easiest way to control the pest infection. However, excessive utilization of pesticide is hazardous to environment. The recent advances in deep learning have paved the way for early detection and improved classification of pest in tomato plants which will benefit the farmers. This paper presents a comprehensive analysis of 11 state-of-the-art deep convolutional neural network (CNN) models with three configurations: transfers learning, fine-tuning and scratch learning. The training in transfer learning and fine tuning initiates from pre-trained weights whereas random weights are used in case of scratch learning. In addition, the concept of data augmentation has been explored to improve the performance. Our dataset consists of 859 tomato pest images from 10 categories. The results demonstrate that the highest classification accuracy of 94.87% has been achieved in the transfer learning approach by DenseNet201 model with data augmentation.


2020 ◽  
Vol 10 (2) ◽  
pp. 84 ◽  
Author(s):  
Atif Mehmood ◽  
Muazzam Maqsood ◽  
Muzaffar Bashir ◽  
Yang Shuyuan

Alzheimer’s disease (AD) may cause damage to the memory cells permanently, which results in the form of dementia. The diagnosis of Alzheimer’s disease at an early stage is a problematic task for researchers. For this, machine learning and deep convolutional neural network (CNN) based approaches are readily available to solve various problems related to brain image data analysis. In clinical research, magnetic resonance imaging (MRI) is used to diagnose AD. For accurate classification of dementia stages, we need highly discriminative features obtained from MRI images. Recently advanced deep CNN-based models successfully proved their accuracy. However, due to a smaller number of image samples available in the datasets, there exist problems of over-fitting hindering the performance of deep learning approaches. In this research, we developed a Siamese convolutional neural network (SCNN) model inspired by VGG-16 (also called Oxford Net) to classify dementia stages. In our approach, we extend the insufficient and imbalanced data by using augmentation approaches. Experiments are performed on a publicly available dataset open access series of imaging studies (OASIS), by using the proposed approach, an excellent test accuracy of 99.05% is achieved for the classification of dementia stages. We compared our model with the state-of-the-art models and discovered that the proposed model outperformed the state-of-the-art models in terms of performance, efficiency, and accuracy.


Author(s):  
Santosh Tiwari ◽  
Georges Fadel ◽  
Vladimir Gantovnik

In this paper, we investigate the current state-of-the-art in packing algorithms. The focus of this survey is on the different types of encoding schemes and associated placement techniques used to represent the layout of a set of objects. The encoding schemes are investigated with respect to their suitability to different types of packing problems, specific scenarios where a given representation may outperform others and their limitations. The different types of placement algorithms that can be used with a given encoding are described. Some common desirable characteristics that an encoding scheme should follow are also discussed. Finally a qualitative comparison of the various encoding schemes is presented to help in selecting a specific representation based on a set of criteria.


2020 ◽  
Vol 10 (5) ◽  
pp. 1040-1048 ◽  
Author(s):  
Xianwei Jiang ◽  
Liang Chang ◽  
Yu-Dong Zhang

More than 35 million patients are suffering from Alzheimer’s disease and this number is growing, which puts a heavy burden on countries around the world. Early detection is of benefit, in which the deep learning can aid AD identification effectively and gain ideal results. A novel eight-layer convolutional neural network with batch normalization and dropout techniques for classification of Alzheimer’s disease was proposed. After data augmentation, the training dataset contained 7399 AD patient and 7399 HC subjects. Our eight-layer CNN-BN-DO-DA method yielded a sensitivity of 97.77%, a specificity of 97.76%, a precision of 97.79%, an accuracy of 97.76%, a F1 of 97.76%, and a MCC of 95.56% on the test set, which achieved the best performance in seven state-of-the-art approaches. The results strongly demonstrate that this method can effectively assist the clinical diagnosis of Alzheimer’s disease.


2020 ◽  
Vol 17 (2) ◽  
pp. 445-458
Author(s):  
Yonghui Dai ◽  
Bo Xu ◽  
Siyu Yan ◽  
Jing Xu

Cardiovascular disease is one of the diseases threatening the human health, and its diagnosis has always been a research hotspot in the medical field. In particular, the diagnosis technology based on ECG (electrocardiogram) signal as an effective method for studying cardiovascular diseases has attracted many scholars? attention. In this paper, Convolutional Neural Network (CNN) is used to study the feature classification of three kinds of ECG signals, which including sinus rhythm (SR), Ventricular Tachycardia (VT) and Ventricular Fibrillation (VF). Specifically, different convolution layer structures and different time intervals are used for ECG signal classification, such as the division of 2-layer and 4-layer convolution layers, the setting of four time periods (1s, 2s, 3s, 10s), etc. by performing the above classification conditions, the best classification results are obtained. The contribution of this paper is mainly in two aspects. On the one hand, the convolution neural network is used to classify the arrhythmia data, and different classification effects are obtained by setting different convolution layers. On the other hand, according to the data characteristics of three kinds of ECG signals, different time periods are designed to optimize the classification performance. The research results provide a reference for the classification of ECG signals and contribute to the research of cardiovascular diseases.


2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Enbiao Jing ◽  
Haiyang Zhang ◽  
ZhiGang Li ◽  
Yazhi Liu ◽  
Zhanlin Ji ◽  
...  

Based on a convolutional neural network (CNN) approach, this article proposes an improved ResNet-18 model for heartbeat classification of electrocardiogram (ECG) signals through appropriate model training and parameter adjustment. Due to the unique residual structure of the model, the utilized CNN layered structure can be deepened in order to achieve better classification performance. The results of applying the proposed model to the MIT-BIH arrhythmia database demonstrate that the model achieves higher accuracy (96.50%) compared to other state-of-the-art classification models, while specifically for the ventricular ectopic heartbeat class, its sensitivity is 93.83% and the precision is 97.44%.


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