scholarly journals Ambient PM2.5 and Annual Lung Cancer Incidence: A Nationwide Study in 295 Chinese Counties

2020 ◽  
Vol 17 (5) ◽  
pp. 1481 ◽  
Author(s):  
Huagui Guo ◽  
Weifeng Li ◽  
Jiansheng Wu
Keyword(s):  
Lung Cancer ◽  
Cancer Incidence ◽  
Cancer Registries ◽  
Developed Countries ◽  
Incidence Rates ◽  
Lung Cancer Incidence ◽  
Lag Effects ◽  
Temperature And Precipitation ◽  
Males And Females

Most studies have examined PM2.5 effects on lung cancer mortalities, while few nationwide studies have been conducted in developing countries to estimate the effects of PM2.5 on lung cancer incidences. To fill this gap, this work aims to examine the effects of PM2.5 exposure on annual incidence rates of lung cancer for males and females in China. We performed a nationwide analysis in 295 counties (districts) from 2006 to 2014. Two regression models were employed to analyse data controlling for time, location and socioeconomic characteristics. We also examined whether the estimates of PM2.5 effects are sensitive to the adjustment of health and behaviour covariates, and the issue of the changing cancer registries each year. We further investigated the modification effects of region, temperature and precipitation. Generally, we found significantly positive associations between PM2.5 and incidence rates of lung cancer for males and females. If concurrent PM2.5 changes by 10 μg/m3, then the incidence rate relative to its baseline significantly changes by 4.20% (95% CI: 2.73%, 5.88%) and 2.48% (95% CI: 1.24%, 4.14%) for males and females, respectively. The effects of exposure to PM2.5 were still significant when further controlling for health and behaviour factors or using 5 year consecutive data from 91 counties. We found the evidence of long-term lag effects of PM2.5. We also found that temperature appeared to positively modify the effects of PM2.5 on the incidence rates of lung cancer for males. In conclusion, there were significantly adverse effects of PM2.5 on the incidence rates of lung cancer for both males and females in China. The estimated effect sizes might be considerably lower than those reported in developed countries. There were long-term lag effects of PM2.5 on lung cancer incidence in China.

scholarly journals Trends in lung cancer incidence by age, sex and histology from 2012 to 2025 in Catalonia (Spain)

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Laura Guarga ◽  
Alberto Ameijide ◽  
Rafael Marcos-Gragera ◽  
Marià Carulla ◽  
Joaquim Delgadillo ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Carcinoma ◽  
Cancer Incidence ◽  
Cancer Registries ◽  
Tobacco Consumption ◽  
Incidence Rates ◽  
Histological Type ◽  
Multidisciplinary Teams ◽  
Lung Cancer Incidence ◽  
Incident Cases

AbstractLung cancer remains one the most common cancers in Europe and ranks first in terms of cancer mortality in both sexes. Incidence rates vary by region and depend above all on the prevalence of tobacco consumption. In this study we describe recent trends in lung cancer incidence by sex, age and histological type in Catalonia and project changes according to histology by 2025. Bayesian age-period-cohort models were used to predict trends in lung cancer incidence according to histological type from 2012 to 2025, using data from the population-based Catalan cancer registries. Data suggest a decrease in the absolute number of new cases in men under the age of 70 years and an increase in women aged 60 years or older. Adenocarcinoma was the most common type in both sexes, while squamous cell carcinoma and small cell carcinoma were decreasing significantly among men. In both sexes, the incident cases increased by 16% for patients over 70 years. Increases in adenocarcinoma and rising incidence in elderly patients suggest the need to prioritize strategies based on multidisciplinary teams, which should include geriatric specialists.

scholarly journals Trends in Lung Cancer Incidence Rates, Oklahoma 2005–2010

PLoS ONE ◽  
2015 ◽  
Vol 10 (4) ◽  
pp. e0119251 ◽  
Author(s):  
Dana S. Mowls ◽  
D. Robert McCaffree ◽  
Laura A. Beebe
Keyword(s):  
Lung Cancer ◽  
Cancer Incidence ◽  
Incidence Rates ◽  
Lung Cancer Incidence ◽  
Cancer Incidence Rates

scholarly journals LUNG CANCER INCIDENCE IN VARIOUS CITIES OF THE WORLD (REVIEW)

2020 ◽  
Vol 66 (3) ◽  
pp. 239-246
Author(s):  
Liliya Zhuykova ◽  
Yevgeniy Choynzonov ◽  
Olga Ananina ◽  
Nina Lyakhova ◽  
Lidiya Pikalova
Keyword(s):  
Lung Cancer ◽  
New York ◽  
New York City ◽  
Cancer Incidence ◽  
Rural Areas ◽  
Urban Areas ◽  
New York State ◽  
Incidence Rates ◽  
Lung Cancer Incidence ◽  
Cancer Incidence Rates

Apart from smoking, an urban factor is an established risk factor for lung cancer. Lung cancer is associated with environmental factors, occupational exposure, bad habits and lifestyle factors. Approximately 17% of the annual deaths from lung cancer among adults are attributable to exposure to carcinogens located in the surface layer of the urban atmosphere, with industrial pollution and occupational hazards. According to recent data, 97% of cities in low- and middle-income countries with a population of more than 100 thousand people do not meet WHO recommendations for air quality; in high-income countries, this figure has been reduced to 49%. In the United States, the studies demonstrated that the prevalence of combined lung cancer was higher in urban areas (10.2%) than in rural areas (4.8%). There was a difference in the lung cancer incidence rates between the populations of the New York City and the New York State. In males, the lung cancer incidence rates were 1.4 times higher in the New York City than in the New York State (68.9 ± 1.2 0/0000 versus 48.5 ± 0.2 0/0000). In females, the lung cancer incidence rates were 1.2 times higher in the New York City than in the New York State (43.0 ± 0.3 and 34.9 ± 0.1 0/0000, respectively). In China, in urban areas, the lung cancer incidence mortality rates were 36.6 0/0000 and 28.9 0/0000, respectively. In rural areas, the corresponding values were 33.4 and 26.6 0/0000, respectively. Although the lung cancer incidence and mortality rates are higher in urban areas than in rural areas, these differences are gradually decreasing: the incidence rate between urban and rural areas has decreased from 2.1 to 1.1. The issue of the impact of environment on the incidence of lung cancer is challenging. The outdoor environment affects people’s health with varying degrees of intensity both in time and in space.

scholarly journals LUNG CANCER INCIDENCE AND MORTALITY IN THE KHANTY-MANSI AUTONOMOUS OKRUG – YUGRA

2021 ◽  
Vol 20 (4) ◽  
pp. 30-38
Author(s):  
A. A. Mordovskii ◽  
A. A. Aksarin ◽  
A. M. Parsadanyan ◽  
M. D. Ter-Ovanesov ◽  
P. P. Troyan
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
Mortality Rate ◽  
Cancer Incidence ◽  
Mortality Rates ◽  
Incidence Rates ◽  
Lung Cancer Incidence ◽  
Cross Correlation Analysis ◽  
Incidence And Mortality ◽  
Khanty Mansi Autonomous

The aim of the study was to assess the lung cancer incidence and mortality in the Khanty-mansi autonomous okrug – Yugra during the period 1999–2019.Material and methods. We have studied the lung cancer incidence and mortality rates in Yugra over the last 21 years (1999–2019).Results. In Yugra, the lung cancer (lc) incidence rates increased by 24.7 % from 1999 to 2019, demonstrating higher rates than those in the Russian Federation (RF), where lc incidence rates decreased by 20.3 %. In 2019, the age-standardized incidence rate was 30.5 per 100,000 (22.7 for RF); the age-standardized mortality rate was 16.4 per 100,000 (18.4 for RF). The mortality rate from lc in Yugra was 9.6 times higher in males than in females (35.5 vs. 3.7 per 100,000). The cross-correlation analysis revealed a correlation between the lc incidence/mortality and air pollution in Yugra. The main carcinogens in Yugra were formaldehyde, phenol, nitrogen dioxide, and benzapyrene. The assessment of the relationship between the age-standardized lc incidence/mortality rates and the amount of pollutants emitted into the atmosphere revealed that their synergistic effects with tobacco smoking can double the risk of lung cancer development. The increase in the number of chest computed tomography (ct) scans performed in the context of the pandemic caused by covid-19 infection led to an 18 % increase in the number of incidentally detected pulmonary nodules, of which 9 % of cases were diagnosed as lc.Conclusion. The lc incidence rates in Yugra tended to increase. The high rate of lc incidence is caused by man-made and natural factors, which requires the implementation of a screening program with the use of low-dose computed tomography in order to improve the early detection and prevention of this disease.

scholarly journals Epidemiological Study of Lung Cancer Incidence in Lebanon

Medicina ◽  
2019 ◽  
Vol 55 (6) ◽  
pp. 217 ◽  
Author(s):  
Hamza A. Salhab ◽  
Mohamad Y. Fares ◽  
Hussein H. Khachfe ◽  
Hassan M. Khachfe
Keyword(s):  
Lung Cancer ◽  
Incidence Rate ◽  
Cancer Incidence ◽  
Incidence Rates ◽  
Lung Cancer Incidence ◽  
Cancer Incidence Rate ◽  
Mena Region ◽  
Mena Countries ◽  
Common Cancer ◽  
The World

Background and Objectives: Lung cancer (LC) is the most common cancer in the world. Developing countries in the Middle East and North Africa (MENA) region, including Lebanon, have witnessed a great increase in the incidence rates of this disease. The aim of our study is to investigate the incidence rates of lung cancer in Lebanon from 2005 to 2015 and to compare these rates to other countries from the MENA region and other regions of the world. Material and Methods: Lung cancer data for the years 2005–2015 were collected from the National Cancer Registry of Lebanon and stratified by gender and age group. Age-specific and age-standardized incidence rates were calculated and analyzed using joinpoint regression. Age-standardized incidence rates to the world population (ASR(w)) for other countries were obtained from two online databases. Results: Lung cancer ranked as the second most common cancer in Lebanon and accounted for 9.2% of all newly diagnosed cancers. Lung cancer ASR(w) showed a significantly increasing trend over the period studied for males and females. Lung cancer ASR(w) among males in Lebanon came second after Malta when compared to other MENA countries, but it was among the lowest when compared to non-MENA countries. For females, Lebanon ranked first when compared to other MENA countries but was among the lowest when compared to countries in other regions of the world. The lung cancer incidence rate increased with age in both sexes and 89.2% of patients were 50 years of age or older. Conclusion: Lebanon has the highest incidence of LC in females and the second highest for males in the MENA region. The lung cancer incidence rate is on the rise and older age groups are much more burdened by this disease than the young ones. Several risk factors, particularly smoking, play a role in increased LC incidence among the Lebanese population.

scholarly journals Lung Cancer Incidence and Long-Term Exposure to Air Pollution from Traffic

2011 ◽  
Vol 119 (6) ◽  
pp. 860-865 ◽  
Author(s):  
Ole Raaschou-Nielsen ◽  
Zorana Jovanovic Andersen ◽  
Martin Hvidberg ◽  
Steen Solvang Jensen ◽  
Matthias Ketzel ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Air Pollution ◽  
Cancer Incidence ◽  
Lung Cancer Incidence
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