scholarly journals Comparison of Maternal Functioning between Iranian Mothers with and without Depressive Symptoms: A Case-Control Study

2020 ◽  
Vol 17 (10) ◽  
pp. 3350
Author(s):  
Fatemeh Karami Chamgurdani ◽  
Jennifer L. Barkin ◽  
Carolann L. Curry ◽  
Mojgan Mirghafourvand
Keyword(s):  
Depressive Symptoms ◽  
Postpartum Depression ◽  
Case Control Study ◽  
Pearson Correlation ◽  
Control Group ◽  
Case Group ◽  
Maternal Functioning ◽  
The Mean ◽  
And Control ◽  
Control Study

Postpartum depression (PPD) has adverse effects on the mother’s ability to work, her relationships, performance in other roles, and caregiving ability. The aim of this study was to compare levels of maternal functioning between mothers with depression symptoms and those without. The participants of this case-control study included 80 postpartum women (n = 40 with depressive symptoms and n = 40 with no depressive symptoms) referred to health centers in Tabriz, Iran, in 2018–2019. The case and control groups were matched for the number of deliveries (first or second deliveries) and the type of delivery (vaginal or cesarean section). A sociodemographic questionnaire, Edinburgh Postpartum Depression Scale (EPDS), and Barkin Index of Maternal Functioning (BIMF) were used for data collection. The relationship between maternal functioning and depression was assessed by conducting independent t-tests and Pearson correlation tests in bivariate analysis and applying the general linear model (GLM) in a multivariate analysis. There was no statistically significant difference between the two groups in terms of sociodemographic information. The mean (SD) total scores of maternal functioning in the case (depressed) and control (non-depressed) groups were 63.4 (12.2) and 93.3 (13.0), respectively. According to the independent t-test, this value in the control group was significantly higher than that of the case group (mean difference: −30.0; 95% confidence interval: −35.6 to −24.3; p < 0.001). In terms of the domains of the BIMF, based on the independent t-test, the mean score of all domains in the control group was significantly higher than that of the case group, except for the mother-child interaction dimension (p = 0.219). Based on the Pearson correlation test, there was significant negative correlation between the PPD score and total score of BIMF (r = −0.79, p < 0.001) and its domains (r = −0.81 to −0.54, p < 0.001). In addition, based on the GLM with adjusting the sociodemographic and obstetrics characteristics, the score of maternal functioning was significantly lower in the case group compared to the control group [β = −30.1; 95% CI: −36.8 to −23.4; p = 0.001]. The results of this study indicate that women with depressive symptoms have lower maternal functioning. Depressed women may find it difficult to perform their maternal duties and take care of themselves and other family members due to the burden of the depressive symptoms. Therefore, early diagnosis and treatment of postpartum depression can play an important role in improving daily maternal functioning.

scholarly journals Mental and personality disorders in infertile women with polycystic ovary: a case-control study

2020 ◽  
Vol 20 (3) ◽  
pp. 1241-1249
Author(s):  
Mostafa Ahmadi ◽  
Mahbobeh Faramarzi ◽  
Zahra Basirat ◽  
Farzan Kheirkhah ◽  
Mohammad Chehrazi ◽  
...  
Keyword(s):  
Personality Disorders ◽  
Polycystic Ovarian Syndrome ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
Infertile Women ◽  
The Mean ◽  
Ovarian Syndrome ◽  
Control Study

Background: Polycystic Ovarian Syndrome (PCOS) is one of the most common causes of infertility in women. Objective: The current study investigated mental and personality disorders in infertile women with and without PCOS. Methods: This case-control study evaluated 400 infertile women who referred to the Infertility Center in Babol city (North of Iran). Participants were categorized into the case group (201 PCOS) and the control group (199 without PCOS). All of the participants completed the Millon Clinical Multi-axial Inventory-III (MCMI-III). Results: The mean scores for clinical personality patterns were significantly higher for six personality disorders (schiz- oid, avoidant, antisocial, depressive, sadistic, and negativistic) and for three classes of severe personality disorder patterns (schizotypal, borderline, and paranoid) in infertile women with PCOS than in women without PCOS. The mean scores for eight clinical disorders (somatoform, manic disorder, dysthymia, alcohol-dependence, drug-dependence, post-trauma stress disorder, major depression, and delusion disorder) were also higher in infertile women with PCOS than in women without PCOS. Conclusion: The scores of many mental and personality disorders are higher in infertile women with PCOS than in women without PCOS. Thus, clinicians should prioritize recognizing and treating psychological problems of infertile women with PCOS. Keywords: Polycystic ovarian syndrome; infertility; personality disorders.

A Case-Control Study on the p73 G4A Gene Polymorphism and Susceptibility to Breast Cancer in an Iranian Population

2020 ◽  
Author(s):  
Zeinab TAVAKKOL AFSHARI ◽  
Zahra GHOLIZADEH ◽  
Amin Reza NIKPOOR ◽  
Jalil TAVAKKOL AFSHARI ◽  
Rashin GANJALI ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Iranian Population ◽  
Control Group ◽  
Case Group ◽  
Medical Sciences ◽  
Control Groups ◽  
And Control ◽  
Control Study

Background: The tumor protein p73 (TP73) is a homolog of TP53 family. Ectopic p73 overexpression largely mimics p53 activities as a tumor suppressor and activates the transcription of p53-responsive genes and as a result induce apoptosis. This study aimed to investigate the association between p73 G4A polymorphism and the risk of breast cancer in a northeastern Iranian population. Methods: This case-control study was performed on 105 patients who admitted in educational hospitals of Mashhad University of Medical Sciences, Iran during 2013-2015, with breast cancer as case group and 120 healthy women as the control group. PCR-CTPP method was used to investigate the relationship between the p73 G4A polymorphism and the risk of breast cancer. Results: There was no significant association between the AA genotype of the p73 G4A polymorphism and breast cancer in case and control groups. Although G allele frequency was higher in the case group, the abundance of this allele between case and control groups was not statistically meaningful and, as a result, not associated with the risk of breast cancer in this study group. Conclusion: There was no association between G4A p73 polymorphism and the risk of breast cancer in a northeastern Iranian population.  

scholarly journals Tooth eruption sequence and dental crowding: a case-control study

F1000Research ◽  
2014 ◽  
Vol 3 ◽  
pp. 122 ◽  
Author(s):  
Vahid Moshkelgosha ◽  
Negar Khosravifard ◽  
Ali Golkari
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Mixed Dentition ◽  
Control Group ◽  
Case Group ◽  
Significant Difference ◽  
The Mean ◽  
Mandibular Canine ◽  
Dental Crowding ◽  
Control Study

When cases of dental crowding are identified and diagnosed promptly, interceptive orthodontics is particularly successful.Aim: To assess the differences in the eruption sequence of the mandibular canine and first premolar teeth in children with and without dental crowding.Materials and Methods: Children who attended the Shiraz Dental School's orthodontic clinic (Iran) from September to December 2012 were enrolled in this case-control study. Tooth size arch length discrepancy (TSALD) of all 8-10 year olds was calculated from patients’ dental models. Thirty-six children were randomly selected from those with TSALD of equal or less than 4mm (those with crowding). Each selected case was matched for sex and age with another child (as control) with TSALD>−4mm attending the same clinic, in the same time period. The existing panoramic radiographs were traced and the eruption percentages were measured for mandibular canine and first premolar teeth. The mean difference between canine and first premolar eruption percentages was compared between the case and control groups using the SPSS (version PASW 18) software and a paired sample t-test.Results: Canine and first premolar eruption percentages in the case group were 65.82±13.00 and 78.92±10.15 percent, respectively. The mean eruption percentages for canines and first premolars of the control group were 74.12±14.55 and 75.47±11.60 percent, respectively. There was a significant difference in pre-eruptive positions of canine and first premolar teeth in those with moderate to severe crowding when compared to the control group (p<0.001).Conclusion: These findings may improve the early diagnosis of children with high risk of developing moderate to severe crowding during mixed dentition.

scholarly journals Prevalence of antinuclear antibody in patients with multiple sclerosis: a case-control study

2021 ◽  
Vol 57 (1) ◽  
Author(s):  
Hind Alnajashi ◽  
Foziah Alshamrani
Keyword(s):  
Multiple Sclerosis ◽  
Antinuclear Antibody ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Convenience Sample ◽  
The Mean ◽  
And Control ◽  
Control Study ◽  
Clinical Examination Finding

Abstract Background Antinuclear antibody (ANA) is a common test for excluding alternative diagnoses. However, the significance of ANA testing in patients with multiple sclerosis (MS) remains unclear. Objectives To compare the prevalence of positive ANA antibody and its titer between patients with MS (cases) and non-MS patients who attended neurology clinics (control) in Saudi Arabia. Methods A case-control review of ANA results for all patients who attended a neurology MS clinic. We compared a convenience sample of patients with MS with individuals with general neurology problems and no known autoimmune diseases. Results There were 115 and 103 participants in the MS and control group, respectively. The mean age in the MS and control group was 33.76 ± 8.96 years and 34.95 ± 8.56 years, respectively. In the MS group, 25.22%, 60%, 11.30%, and 3.48% were negative, mildly positive, moderately positive, and strongly positive for ANA, respectively. In the control group, there were 34.95%, 54.37%, and 10.68% were negative, mild positive, and moderate positive, respectively. There were numerically, but not significantly, more positive cases in the MS group (74.78%) than in the control group (65.05%) (p = .117). Conclusion ANA testing in routine MS screening for excluding alternative diagnoses should be discouraged unless there is a remarkable history or clinical examination finding. Mild positive ANA is common among patients with MS and does not significantly differ from the general population.

scholarly journals Association of Serum C-reactive Protein in Preeclampsia and its Effect on Fetal Birth Weight – A Case Control Study

2017 ◽  
Vol 31 (2) ◽  
pp. 75-80 ◽  
Author(s):  
Shahanaj Sharmin ◽  
Shahanara Chy ◽  
Diadrul Alam ◽  
Nasreen Banu ◽  
Fahmida Rashid ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Birth Weight ◽  
Pregnant Women ◽  
Case Control Study ◽  
Control Group ◽  
Case Group ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
The Mean ◽  
Control Study

Objective(s): The aim of this study was to evaluate the association of serum C-reactive protein (CRP) in preeclampsia (PE) and its effect on fetal birth weight.Materials and methods: This case control study was conducted in Chittagong Medical College Hospital, Bangladesh, from July 2013 to June 2014. Study population was pregnant women of third trimester with preeclampsia (case group) and normal blood pressure (control group). The maternal serum C-reactive protein (CRP) levels were measured by immune turbidometric assay between 32 weeks to term. The women were divided into three groups: mild PE, severe PE (according to ACOG criteria) and normal healthy group. The value of CRP and its correlation with birth weight was compared between groups.Results: One hundred and fifty (150) pregnant women were analyzed. Among them 50 were case and 100 control. There was no difference between age of the patients of both groups. The mean systolic blood pressure was 148.40 ± 12.35 mm Hg in case and 122.15 ± 6.44 mmHg in control group. The mean diastolic blood pressure was 100.00 ± 9.74 mmHg in case and 74.05 ± 5.97 mmHg for the control. The systolic and diastolic blood pressure was significantly higher in preeclamptic group (P < 0.000). C-reactive protein was 10.28 ± 7.25 mg/ mL in mild PE and 10.94 ± 6.32 mg/mL in severe PE and 3.45 ± 1.71 mg/mL in normotensive group, which was significantly higher in case than control group (P = 0.000). Preeclamptic women delivered at a significantly shorter gestational age than normal pregnant women. Mean gestational age during delivery for the case group and control group was 39.02 ± 1.6 and 39.58 ± 0.8 weeks respectively. Mean birth weight in PE (2.52 ± 0.42 kg) was significantly lower than normal pregnancies (2.88 ± 0.29 kg). The sensitivity and specificity of CRP were 68% and 98% respectively. Multiple regression analysis showed that there is a strong association between CRP levels and PE and birth weight.Conclusion: This small study showed that in case group CRP was raised in 68% cases which is much higher in comparison to healthy control group where CRP was high only in 2% cases. High CRP has association with low birth weight. Therefore, CRP may be used as cost effective investigation to identify the risk of preeclampsia and its effect on fetal birth weight.Bangladesh J Obstet Gynaecol, 2016; Vol. 31(2) : 75-80

scholarly journals ASSESSMENT OF QUALITY OF LIFE IN PRIMARY OPEN ANGLE GLAUCOMA PATIENTS: A CASE-CONTROL STUDY.

2020 ◽  
Vol 4 (4) ◽  
Author(s):  
Archana Kumari ◽  
Sony Sinha
Keyword(s):  
Quality Of Life ◽  
Case Control Study ◽  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
And Control ◽  
Control Study

Aim: to evaluate quality of life in primary open angle glaucoma patients using a standard questionnaire. Material and methods: The present prospective case-control study was conducted in the department of Ophthalmology, Patna Medical College and Hospital, Patna, Bihar, India. The study included 200 subjects who were divided into (case group n=100) and (control group n=100). Quality of life was assessed using Glaucoma Quality Of Life-15 Questionnaire (GQOL-15).   Results: Mean age of patients in case group (n=100) and control group (n=100) was 57.97 years, and 57.84 years respectively. Overall QOL score was significantly between the two groups (p<0001). QOL score increases as the Glaucoma Severity score increases. Conclusion: QOL of patients with glaucoma was found poor as compared to control group. It showed a clear trend of worsening QOL scores with increasing severity of disease. Keywords: Glaucoma, Quality of life, QOL-15

scholarly journals Association of Genetic Polymorphisms in FOXA1 with the Progression of Genetic Susceptibility to Gastric Cancer

2020 ◽  
Vol 2020 ◽  
pp. 1-8 ◽  
Author(s):  
Guo-wen Ding ◽  
Xu-yu Gu ◽  
Zhe Dai ◽  
Hui-wen Pan ◽  
Xiao-yan Wang ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Target Gene ◽  
Case Control Study ◽  
Control Group ◽  
Case Group ◽  
Significant Difference ◽  
Drinking Status ◽  
And Control ◽  
The Relationship ◽  
Control Study

Objective. To investigate the relationship between polymorphism of FOXA1 gene rs12894364 and rs7144658 and susceptibility to gastric cancer. Methods. A case-control study was conducted to select 577 cases of primary gastric cancer and 678 cases of normal control. We extracted whole blood genomic DNA and amplified the target gene fragment by PCR. The genotyping and allele was tested through a snapshot method. Results. There was no significant difference in the frequency distribution of genotype between the case group and control group (P>0.05). Stratified analyses showed the SNPs were not correlated with the susceptibility of GC according to different age, gender, cigarette smoking, and alcohol drinking status. Conclusion. There is no significant correlation between the polymorphisms of FOXA1 gene rs12894364 and rs7144658 and the risk of gastric cancer.

scholarly journals The Serum Level of Vitamin D in Women With Urinary Incontinence Due to Pelvic Floor Disorder and Prolapse: A Regional Case-Control Study on Iranian Population

2018 ◽  
Vol 7 (1) ◽  
pp. 67-73
Author(s):  
Shahnaz Barat ◽  
Zinatossadat Bouzari ◽  
Shabnam Mehdinia ◽  
Karimollah Hajian-Tilaki ◽  
Mojgan Naeimi Rad
Keyword(s):  
Vitamin D ◽  
Urinary Incontinence ◽  
Serum Level ◽  
Pelvic Floor ◽  
Case Control Study ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
The Mean ◽  
Control Study

Objectives: Vitamin D is important for the muscular tone and bone metabolism. Due to the high prevalence of vitamin D deficiency in Iranian women, this study aimed to investigate the difference in vitamin D levels between patients with and without pelvic floor disorder (PFD) to assess the possible effect of vitamin D on PFD. Materials and Methods: The present case-control study examined 209 women referring to Ayatollah Rouhani hospital of Babol in 2017. Patients were explored for prolapse and those with at least one disorder or without PFD were categorized as the case (n = 104) or control (n = 105) groups, respectively. Then, the serum level of 25-hydroxy vitamin D was compared between the groups. Results: The mean age and abdominal circumference of the patients were significantly higher in the case group (P < 0.001 & P = 0.046, respectively) as compared to the control group. Meanwhile, the total mean ± SD serum level of vitamin D was 20.03±17.88 ng/ mL and significantly higher in the case group (24.58 ± 20.75 ng/mL) than that of the control group (15.53±13.11 ng/mL), especially in patients with stress and urgency urinary incontinence (SIU/UIU) (both with a significance level of P < 0.001). Conclusions: As a result of PFD, the group with UI, especially the one with SIU or UIU had the highest vitamin D level compared to the control and other groups. Nonetheless, the mean age and educational level were significantly higher and lower in this group, respectively. These results could be due to the multifactorial nature of vitamin D level, that is, it varies based on nutrition, place of residence, and other factors.

scholarly journals FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN PEDICULOSIS CAPITIS DI SMP DARUL HIJRAH PUTRI MARTAPURA: CASE CONTROL STUDY

2017 ◽  
Vol 4 (2) ◽  
pp. 124
Author(s):  
Sovia Yunida ◽  
Kurnia Rachmawati ◽  
Musafaah Musafaah
Keyword(s):  
Case Control Study ◽  
Head Louse ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
Pediculosis Capitis ◽  
Sleep Habit ◽  
Pediculus Humanus ◽  
And Control ◽  
Control Study

ABSTRAKPediculosis capitis adalah infestasi yang disebabkan oleh pediculus humanus var. capitis dan merupakan masalah kesehatan anak-anak yang tinggal di asrama. Sampai saat ini penelitian tentang hal yang menyebabkan kutu kepala masih terbatas. Tujuan penelitian untuk mengetahui faktor-faktor yang berhubungan dengan kejadian pediculosis capitis pada anak-anak yang tinggal di asrama. Metode penelitian ini menggunakan studi kasus kontrol, pada siswi SMP pondok pesantren dan dilakukan tanggal 09 Desember 2015. Responden dibagi dalam 2 kelompok yaitu kelompok kasus (n=48) dan kelompok kontrol (n=48). Pemeriksaan kutu kepala dilakukan menggunakan sisir bergigi rapat dan respon pasien dicatat dalam lembar checklist. Hasil penelitian tidak terdapat hubungan antara faktor-faktor risiko yaitu panjang rambut (p=0,321), frekuensi mencuci rambut dalam seminggu (p=0,117), berbagi sisir (p=0,301), berbagi handuk (p=1,000), berbagi penutup kepala (kerudung) (p=0,323), kebiasaan tidur atau penggunaan tempat tidur bersama (p=0,784), dan frekuensi mengganti sprei tempat tidur sekali seminggu (p=0,268), dengan kejadian pediculosis capitis. kesimpulan pada penelitian tidak terdapat hubungan antara faktor-faktor dengan kejadian pediculosis capitis, hal ini mungkin disebabkan oleh faktor lain yaitu kepadatan hunian.Kata-kata kunci: pediculosis capitis, kutu kepala, faktor risiko.ABSTRACTPediculosis capitis is an infestation caused by pediculus humanus var. capitis and it is one of health problem on children who lived in a dormitory. Unfortunately, recent research about things caused head louse is still limited. The objective was to determine the factors which had correlation with pediculosis capitis incident in children who lived in dormitory. The method of this research used case control study, performed to girl students in SMP Pondok Pesantren on 09 December 2015. Respondents were divided into 2 groups, case group (n=48) and control group (n=48). The examination of head louse was performed using tight-brush comb and patient’s response has written in checklist paper. The result there was no correlation between hair long (p=0,321), frequency of hair washing in a week (p=0,117), shared comb (p=0,301), shared towel (p=1,000), shared head cover (jilbab) (p=0,323), sleep habit or shared bed (p=0,784), and frequency of changing bed cover once a week (p=0,268), with pediculosis capitis incident. It can be concluded this study there was no correlation between factors with pediculosis capitis incidence, this happened maybe because of other factor like occupancy density.Keywords: pediculosis capitis, head louse, risk factor.

scholarly journals Fecal Calprotectin in patients with Infantile Colic: A case-control study

2020 ◽  
Author(s):  
Parisa Khoshnevisasl ◽  
mansour sadeghzadeh ◽  
Neda Mahmoudirad ◽  
Nima Motamed
Keyword(s):  
Case Control Study ◽  
Fecal Calprotectin ◽  
Case Control ◽  
Control Group ◽  
Case Group ◽  
Infantile Colic ◽  
Healthy Infants ◽  
Significant Difference ◽  
And Control ◽  
Control Study

Abstract Back groundThe precise etiology of infantile colic has not been elucidated after many years of research. In this study, we aimed to determine the association of fecal calprotectin with infantile colic.MethodThis case control study was performed on colicky infants referred to pediatrics clinics in Zanjan over a 6-month period. Infantile colic was clinically defined based on wessel criteria. The control group consisted of healthy infants matched for age, sex, weight, and type of feeding with the case group. Fecal calprotectin levels were measured in both groups by the ELISA method.ResultsForty infants were divided equally into case and control groups. The cases consisted of 11 boys (55%) and 9 girls (45%) with a mean age of 63 days and in the control group there was 12 boys (60%) and 8 girls (40%) with mean age of 48 days. Fecal calprotectin was positive in 17 (85%) cases and 6 (30%) controls. This difference was statistically significant. There was no significant difference in fecal calprotectin regarding sex, age, weight and type of nutrition in both colicky infants and controlsConclusionFecal calprotectin levels in colicky infants were significantly higher than healthy infants.

Sign in / Sign up

Export Citation Format

Share Document