scholarly journals The Impact of ABO Blood Grouping on COVID-19 Vulnerability and Seriousness: A Retrospective Cross-Sectional Controlled Study among the Arab Community

Author(s):  
Nagla A. El-Shitany ◽  
Manal El-Hamamsy ◽  
Ahlam A. Alahmadi ◽  
Basma G. Eid ◽  
Thikryat Neamatallah ◽  
...  

Background and Objectives: Studies have noted that some ABO blood types are more susceptible to COVID-19 virus infection. This study aimed to further confirm the relationship between different blood groups on the vulnerability, symptoms, cure period, and severity among COVID-19 recovered patients. Subjects and Methods: This cross-sectional study approached the participants from the Arab community via social media (mainly Facebook and WhatsApp). The data were collected through two Google Form questionnaires, one for COVID-19 recovered patients (COVID-19 group, n = 726), and the other for the healthy people (Control group, n = 707). Results: The subjects with blood group O were the least likely to be infected with the COVID-19 virus, while those with blood group A were not likely to be the most susceptible. There were significant differences among different ABO blood groups regarding the distribution of oxygen saturation percentage, myalgia, and recovery time after COVID-19 infection (p < 0.01, 0.01, and 0.05, respectively). The blood group A showed the highest percentage of patients who experienced an oxygen saturation range of 90–100%, whereas the blood group O showed the highest percentage of patients who experienced an oxygen saturation range of 70–80%. The blood group A showed the lowest percentage of patients who required artificial respiration, whereas the blood group O showed the highest percentage of patients who required artificial respiration. The blood group B showed the lowest percentage of patients who experienced myalgia and exhibited the lowest percentage of patients who needed 3 weeks or more to recover. Conclusion: The people of blood group O may be the least likely to be infected with COVID-19, however, they may be the more in need of treatment in hospital and artificial respiration compared to the other blood groups.

2008 ◽  
Vol 41 (02) ◽  
pp. 138-140
Author(s):  
Rasoul Gheisari ◽  
Mehdi Ghoreishian ◽  
Movahedian Bijan ◽  
Roozbehi Amrolah

ABSTRACT Background: Blood group is a genetic characteristic which is associated with some diseases and deformities. Multifactorial characteristics of facial development make it difficult to predict a genetic pattern in a specific maxillofacial deformity, but epidemiological evaluations can reveal relationships between such deformities and some genetic characteristics or accompanied diseases, and this will help to recognise and treat them. The aim of this study is evaluation of the relationship between blood groups and maxillofacial deformities. Materials and Methods: In this study, blood groups of 190 patients with maxillofacial deformities who had had orthognathic surgery in Alzahra hospital, Isfahan, were compared with the general Iranian population. Results: Among 190 patients, 93 cases (49%) were men and 97 cases (51%) were women. Fifteen cases (8%) were < 20 years old, 130 cases (68%) were 20-30 years old, and the others (45 cases, 24%) were > 30 years old. The blood group distribution in our samples was as follows: blood group O = 76 cases (40%), blood group A = 58 cases (30%), blood group B = 41 cases (22%), and blood group AB = 15 cases (8%). Among these patients, 31 cases (16%) had maxillary deformities and 27 cases (14%) suffered from mandibular deformities while the other 132 cases (70%) had bimaxillary problems. The Chi-square test showed statistically significant differences between the blood group distribution of the patients of this study and the normal Iranian population ( P < 0.001). Conclusion: It was shown that among different blood groups; those with blood group B have a greater likelihood of association with maxillofacial deformities. On the other hand, the probability of the association of such deformities was the least with blood group A.


2019 ◽  
Vol 26 (11) ◽  
pp. 1820-1824
Author(s):  
Benash Altaf ◽  
Shireen Jawed ◽  
Fakiha Behram ◽  
Zeeshan Ali Khan ◽  
Shakeela Naz

Objectives: Pakistan has highest mortality rate due to hypertension and its complications. Hypertension is a squealed of Pre- hypertension which is believed to start at adolescent and continue to adulthood. Association of blood group with hypertension is evident but still hypothesized. This study aims to find the frequency of prehypertension and its association with blood group. Study Design: Cross sectional study. Setting:  Aziz Fatimah Medical and Dental College, Faisalabad. Period: 15 March’18 to 15 Sep’18. Material and Methods:  It was comprised of in comprised of 100 MBBS students. Demographic data including age, weight, height, waist and hip circumference, and BMI was determined. Blood group was determined with help of conventional slide method. Blood pressure was measured by auscultatory method. Data was analyzed by using SPSS 21. Continuous variables are given in mean and standard deviation. Categorical data was given in frequency and percentages. P value≤ 0.05 is taken as significant. Results: Out of 100 participants most common blood group was group ‘O’ (43%) followed by B (35 %) and AB (13%) and A (9%).36% of total population was pre-hypertensive and 64% were normotensive. Prehypertension is most commonly found in blood group ‘A’ (77%) followed by blood group ‘O’ (46.5%). Significant difference was found in means of SBP (p value= 0.001*) and DBP (p value= 0.000*) among the various blood groups. Conclusion: Most common blood group in studied population was ‘O’ although hypertension was most commonly observed in blood group A followed by ‘O’.


2016 ◽  
Vol 23 (08) ◽  
pp. 1001-1004
Author(s):  
Naila Parveen ◽  
Javeria Rehman ◽  
Syed Hafeezul Hassan ◽  
Zoya Hassan ◽  
Madiha Rehman

Objectives: To find out the association of body mass index with different bloodgroups in medical students. Background: Increased body mass index leads to obesity and is aprominent risk factor for hypertension and diabetes. Blood groups are known to be associatedwith various diseases and recent studies have shown that a particular blood group with thehighest body mass index appeared to be more susceptible to predisposition to hypertension.Study Design: Cross-sectional study. Setting: Liaquat National Medical College, Karachi.Period: June 2015 to September 2015. Methodology: 181 medical students with 85 malesand 96 females and age ranging from 18-22 years. Weight and height of each student wasmeasured using the standard stadiometer and blood groups were determined using the antisera.Results: Mean age of the participants was 19.92 ± 1.10 years. Blood group “O” wasfound to be most prevalent (39.2%) while blood group “AB” was found to be the least (8.3%).Mean BMI of subjects with blood group A, B, AB and O were found to be 24.3 ± 5.04, 22.6 ±3.59, 23.0 ± 2.91 and 23.7 ± 4.20 kg/m2 respectively. The highest BMI was found in subjectswith blood group “A” 24.3 ± 5.04 kg/m2 and lowest in blood group “AB” 23.0 ± 2.91kg/m2. TheRhesus-D positive and male students had greater body mass index 23.6 ± 3.56 than females23.2 ± 3.44. Comparison of overall mean BMI values among different blood groups showedsignificant difference with p-value < 0.001. Conclusion: Blood group “A” and Rhesus-D positivesubjects especially males were found to be the high risk blood type with predisposition tomorbidity associated with increased body mass index.


2019 ◽  
Vol 26 (08) ◽  
pp. 1333-1338
Author(s):  
Muhammad Tahir ◽  
Gohar Ali ◽  
Ali Ismail

The objective of this study was to determine the blood groups among the patients presenting with ischemic stroke either AB blood group or O blood group is more common (frequent) among these patients irrespective of other known factors responsible for stroke. Study Design: Descriptive, Cross-sectional study. Setting: Department of Medicine, Nishtar Hospital Multan. Period: January 2015 to August 2015. Materials & Methods: We included total 292 patients (40-70 years of age), with ischemic stroke documented on CT scan brain of both gender (male and female). Blood sample of these patients were sent to the central laboratory of Nishtar hospital for blood group determination using standard techniques. Results: Mean age was 56.26 ± 8.28 years. Out of the 292 patients, 163 (55.82%) were male and 129 (44.18%). Frequency of blood group A, B, AB and O in patients with ischemic stroke was found to be 114 patients having blood group A (39.04%), 53 patients having blood group B (18.15%), 26 patients having blood group AB (8.90%) and 99 patients having blood group O (33.90%) respectively. Conclusion: Our study results concluded that there is an association between ABO blood groups and ischemic stroke, irrespective of other risk factors. Our study results have observed that individuals belonging to non-O blood groups (A, B, or AB) are at an increased risk of ischemic stroke as compared to O blood group carriers however we did not control possible impact of confounders such as diabetes, hypertension and dyslipidemia etc. Many studies proved that persons with AB blood groups are at increased of atherosclerosis but no study showed that these persons have increased risk of ischemic stroke or not.


2020 ◽  
Author(s):  
Mourad Belaouni ◽  
Elhoucine Malki ◽  
Rabii El Bahraouy ◽  
Bouchra El Maliki ◽  
Mohammed Er-Rami ◽  
...  

AbstractIntroductionGiven the rapid spread, significant morbidity and mortality associated with COVID-19, there has been scientific interest in obtaining data detailing the factors influencing the risk of COVID-19 infection. The aim of this study was to reveal a possible association between the ABO-RH system and the risk of COVID-19 in the Moroccan population.Materials and methodsThis is an analytical cross-sectional study. It was carried out on 1094 patients for the diagnosis of Covid-19 by Rt-PCR at the Moulay Ismaïl military hospital in the province of Meknes. All Rt-PCR negative individuals were used as a comparison group.ResultsAmong the 1094 individuals who were diagnosed, RT-PCR for detection of SARS-CoV-2 was positive for 242 individuals. Comparison of the proportions of blood groups of the two groups showed that the proportion of blood group A in patients with COVID-19 was significantly higher than in people in the comparison group (P = 0.007), while the proportion of blood group O in patients with COVID-19 was significantly lower than in people in the control group (P = 0.017). Comparison of the Rh blood groups of the two groups did not find a significant association (P = 0.608).ConclusionAs demonstrated by several previous studies, we concluded that blood group A was associated with a higher risk of acquiring COVID-19. Equally, the O blood group was associated with a lower risk of infection.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Yuan Fu ◽  
Mulei Chen ◽  
Hao Sun ◽  
Zongsheng Guo ◽  
Yuanfeng Gao ◽  
...  

Abstract Introduction Studies have been performed to identify the association between ABO blood groups and coronary artery disease. However, data is scarce about the impact of ABO blood groups on heart rupture (HR) after acute myocardial infarction (AMI). Methods We conducted a retrospective case–control study that included 61 consecutive patients with HR after AMI during a period from 1 January 2012 to 1 December 2019. The controls included 600 patients who were selected randomly from 8143 AMI patients without HR in a ratio of 1:10. Univariate and multivariate logistic regression analysis were used to identify the association between ABO blood groups and HR. Results Patients with blood group A had a greater risk of HR after AMI than those with non-A blood groups (12.35% vs 7.42%, P < 0.001). After adjusting for age, gender, heart rate at admission, body mass index (BMI), and systolic blood pressure (SBP), blood group A was independently related to the increased risk of HR after AMI (OR = 2.781, 95% CI 1.174–7.198, P = 0.035), and remained as an independent risk factor of HR after AMI in different multivariate regression models. Conclusion Blood group A is significantly associated with increased HR risk after AMI.


2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Richmond Afoakwah ◽  
Edmond Aubyn ◽  
James Prah ◽  
Ekene Kwabena Nwaefuna ◽  
Johnson N. Boampong

The clinical outcome of falciparum malaria in endemic areas is influenced by erythrocyte polymorphisms including the ABO blood groups. Studies have reported association of ABO blood group to resistance, susceptibility, and severity ofP. falciparummalaria infection. Individuals with blood group “A” have been found to be highly susceptible to falciparum malaria whereas blood group “O” is said to confer protection against complicated cases. We analyzed samples from 293 young children less than six years old with malaria in the Korle-Bu Teaching Hospital in Accra, Ghana. It was observed that group O was present in about 16.1% of complicated cases weighed against 40.9% of uncomplicated controls. Individuals with complicated malaria were about twice likely to be of blood groups A and B compared to group O (A versus O, OR = 1.90, 95% CI = 1.59–2.26,P<0.0001; B versus O, OR = 1.82. 95% CI = 1.57–2.23,P<0.0001). Blood group O participants with complicated diseases had low parasitaemia compared to the other blood groups (P<0.0001). This may give blood group O individuals a survival advantage over the other groups in complicated malaria as suggested. Participants with complicated falciparum malaria were generally anaemic and younger than those with uncomplicated disease.


2021 ◽  
Author(s):  
Nazaneen Omer ◽  
Sarwer Ismael ◽  
Heshu Sulaiman Rahman ◽  
Maryam Mohammed

Abstract Background ABO blood group types are among the risk factors of COVID-19 infection in many recent studies. Thus, the objective of this study is to find the relations between ABO types and COVID-19 infection as well as to find out the riskier group that is associated with hospitalization and the need for O2 support. Methods This observational cross-sectional study was done to identify the risk and relations between ABO blood groups and Rh factor of 530 Iraqi-Kurdish patients affected with COVID-19 infection. Among them, 184 patients were severe cases that needed hospitalization while 346 patients were mild to moderate cases that were treated at home. The diagnosis of COVID-19 infection was based on Real-Time Polymerase Chain Reaction (RT-PCR) test, high-resolution Chest CT scan, strong clinical suspicion plus history of the close home or job contact with COVID-19 confirmed patient. Results There were no significant differences in the distribution of ABO blood grouping in the total COVID-19 cases, however, the severity in form of hospitalization and O2 demand was higher in blood group A whereas the lowest in group B. Male patient were significantly older than females with more prolonged illness duration. The duration of COVID-19 illness, the need for plasma, and the rate of mortality were very significantly higher among hospitalized COVID-19 patients than non-hospitalized. In 37.2% of the patient, the initial presentation was a combination of more than one symptom. In 28% of cases, myalgia was the 1st mono-symptomatic presentation. Conclusions Blood group A is associated with the highest rate of hospitalization and O2 demand, besides, the duration of illness and rate of mortality in males were more than females.


2000 ◽  
Vol 6 (1) ◽  
pp. 156-158
Author(s):  
T. Pramanik ◽  
S. Pramanik

The frequencies of ABO and rhesus blood groups vary from one population to another. We studied blood group distribution in 120 Nepalese students; 34% were blood group A, 29% group B, 4% group AB and 32.5% group O. The frequency of Rh-negative blood was 3.33% and Rh-positive 96.66%


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