Relative Susceptibilities of ABO Blood Groups toPlasmodium falciparumMalaria in Ghana

The clinical outcome of falciparum malaria in endemic areas is influenced by erythrocyte polymorphisms including the ABO blood groups. Studies have reported association of ABO blood group to resistance, susceptibility, and severity ofP. falciparummalaria infection. Individuals with blood group “A” have been found to be highly susceptible to falciparum malaria whereas blood group “O” is said to confer protection against complicated cases. We analyzed samples from 293 young children less than six years old with malaria in the Korle-Bu Teaching Hospital in Accra, Ghana. It was observed that group O was present in about 16.1% of complicated cases weighed against 40.9% of uncomplicated controls. Individuals with complicated malaria were about twice likely to be of blood groups A and B compared to group O (A versus O, OR = 1.90, 95% CI = 1.59–2.26,P<0.0001; B versus O, OR = 1.82. 95% CI = 1.57–2.23,P<0.0001). Blood group O participants with complicated diseases had low parasitaemia compared to the other blood groups (P<0.0001). This may give blood group O individuals a survival advantage over the other groups in complicated malaria as suggested. Participants with complicated falciparum malaria were generally anaemic and younger than those with uncomplicated disease.

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ABO Blood Group is Associated with COVID-19 Susceptibility: a Systematic Review and Meta-Analysis

Iberoamerican Journal of Medicine ◽

10.53986/ibjm.2021.0012 ◽

2020 ◽

Vol 3 (1) ◽

pp. 71-84

Author(s):

Richard Chinaza Ikeagwulonu ◽

◽

Chinonyelum Thecla Ezeonu ◽

Mark Uchejeso Obeta ◽

Ngozi Immaculata Ugwu ◽

...

Keyword(s):

Blood Group ◽

Meta Analysis ◽

Blood Groups ◽

Blood Type ◽

Abo Blood Group ◽

Abo Blood Groups ◽

Blood Group A ◽

Search Terms ◽

Group A

Introduction: Conflicting evidences exist that ABO blood groups correlate with the susceptibility to COVID-19 and its clinical outcomes. This study aimed to pool available articles that assessed a possible relationship between COVID-19 and ABO blood groups. Materials and methods: A search was conducted in four databases comprising Pubmed/Medline, Google scholar, Journal storage (JSTOR) and African Journals Online (AJOL) for relevant studies available before 25th August 2020 and contained extractable data on ABO blood type distribution and COVID-19 disease. Search terms included a combination of “ABO blood group, and COVID-19, coronavirus, and SARS-COV-2”. Results: Fourteen articles that met study inclusion criteria were selected from a total of five hundred and eighty-five articles identified through database search. The fourteen articles reviewed comprised of a total of 73934 subjects (13189 SARS-COV-2 positive cases and 60745 controls). Overall, the risk of SARS-COV-2 infection was found to be significantly increased in patients with blood group A with ORs: 1.24 (95%Cl: 1.09-1.41, P = 0.001). Additionally, blood group O subjects were seen to have decreased odds of contracting COVID-19 infection (OR: 0.78, 95%Cl: 0.68 – 0.89, P=0.0003). No significant association was found between ABO blood groups and COVID -19 severity and mortality. Conclusions: Blood group A was associated with a higher risk of SARS-COV-2 infection whereas risk of infection was lower in blood group O subjects. No statistical significant association was found between ABO blood groups and COVID-19 severity and mortality. The precise role of ABO blood group in COVID-19 susceptibility, severity and mortality requires further research for clarification.

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Variations of prothrombin time among ABO blood groups in healthy adults

World Journal of Advanced Research and Reviews ◽

10.30574/wjarr.2021.11.3.0484 ◽

2021 ◽

Vol 11 (3) ◽

pp. 429-435

Author(s):

Afrina Binte Azad ◽

Qazi Shamima Akhter ◽

Mohammad Aminul Islam ◽

Farzana Yeasmin Mukta ◽

Lily Afroz ◽

...

Keyword(s):

Prothrombin Time ◽

Blood Group ◽

Blood Groups ◽

Healthy Adults ◽

Abo Blood Group ◽

Abo Blood Groups ◽

Medical College ◽

Blood Group A ◽

Group A ◽

Group B

Background and objectives: ABO blood group distribution defers with racial and geographic variations. They are related with diseases like cardiovascular diseases, cerebral thromboembolism. Prothrombin time may varies among ABO blood group system which may increase the future risk of thrombosis. The present study is to assess prothrombin time among ABO blood groups in healthy adults. Materials and methods: A prospective type of analytical cross-sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from July 2019 to June 2020. After obtaining ethical clearance, a total 190 healthy adults were selected from different areas of Dhaka city based on inclusion and exclusion criteria, with age ranging from 18-45 years. The subjects were interviewed and detailed history regarding personal, family, medical and drug were taken. Prior to sample collection, informed written consent was taken from the participants. Individuals of blood group A was selected as group A, blood group B as group B, blood group AB as group AB and blood group O as group O. Prothrombin time was measured in the Department of Hematology and BMT Unit, Dhaka Medical College Hospital, Dhaka. Blood grouping was done in the Department of Physiology, Dhaka Medical College, Dhaka.For statistical analysis, One way ANOVA followed by Bonferroni test were considered using SPSS 25.0 version. Results: In this study, blood group B was most common (33.2%). Prothrombin time was lower in blood group A (12.93±0.30 sec), B (12.92±0.61 sec), AB (12.98±0.54 sec) than blood group O (13.08±0.39 sec) which was not statistically significant. Conclusion: It can be concluded that blood group A, B, AB individuals may have more chance of thrombosis due to lower prothrombin time than blood group O individuals.

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Prognostic impact of ABO blood group on type I endometrial cancer in a population of Iranian patients

Human Antibodies ◽

10.3233/hab-200416 ◽

2020 ◽

Vol 28 (4) ◽

pp. 313-317

Author(s):

Shima Mohammadian ◽

Farkhondeh Pouresmaeili ◽

Aida Mohammadian

Keyword(s):

Blood Group ◽

Significant Relationship ◽

Blood Groups ◽

Abo Blood Group ◽

Type I ◽

Prognostic Impact ◽

Abo Blood Groups ◽

Blood Group A ◽

Group A ◽

Iranian Patients

BACKGROUND: Inherited ABO blood group has been shown to play an important role in the pathogenesis of various gynecological cancers including endometrial carcinoma (EC). OBJECTIVE: Our study aimed to determine the prevalence of ABO blood groups in Iranian patients with EC and to investigate the relationship between the blood group and several clinicopathologic parameters in Imam Hossein Hospital. METHODS: One hundred and seventy-five EC patients were selected and analyzed for their clinicopathologic details including ABO blood group, age, menopausal status, body mass index (BMI), tumor grade, and stage of the International Federation of Obstetrics and Gynecology (FIGO). RESULTS: Endometrioid carcinoma was the most common histological type in this case study. Early stages (I and II) were present in 135 individuals (77.1%) and advanced stages (III and IV) appeared in 40 (22.9%) patients. Blood group A was prominent in patients with EC. There was a significant relationship between blood group A and cancer grade (P= 0.024). 23.1% of group A had grade III EC, while this grade appeared in 35.2% of the non-A blood group. There was no significant association between ABO blood groups and other EC clinic-pathological results (P> 0.05). CONCLUSION: Although there was no significant relationship between the ABO blood group and the patients’ clinicopathological characteristics, more studies could provide extensive information about any possible relation between the blood group, especially blood group A, EC, and the grade of the tumor.

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Association of ABO blood groups with presentation and outcomes of confirmed SARS CoV-2 infection: A prospective study in the largest COVID-19 dedicated hospital in Bangladesh

PLoS ONE ◽

10.1371/journal.pone.0249252 ◽

2021 ◽

Vol 16 (4) ◽

pp. e0249252

Author(s):

Reaz Mahmud ◽

Mohammad Aftab Rassel ◽

Farhana Binte Monayem ◽

S. K. Jakaria Been Sayeed ◽

Md Shahidul Islam ◽

...

Keyword(s):

Blood Group ◽

Blood Groups ◽

Abo Blood Groups ◽

Duration Of Symptoms ◽

Presenting Symptoms ◽

Blood Group A ◽

Group I ◽

Significant Difference ◽

Group A ◽

Group Ii

Background Globally, studies have shown conflicting results regarding the association of blood groups with SARS CoV-2 infection. Objective To observe the association between ABO blood groups and the presentation and outcomes of confirmed COVID-19 cases. Design, setting, and participants This was a prospective cohort study of patients with mild-to-moderately severe COVID-19 infections who presented in the COVID-19 unit of Dhaka Medical College Hospital and were enrolled between 01 June and 25 August, 2020. Patients were followed up for at least 30 days after disease onset. We grouped participants with A-positive and A-negative blood groups into group I and participants with other blood groups into group II. Results The cohort included 438 patients; 52 patients were lost to follow-up, five died, and 381 completed the study. The prevalence of blood group A [144 (32.9%)] was significantly higher among COVID-19 patients than in the general population (p < 0.001). The presenting age [mean (SD)] of group I [42.1 (14.5)] was higher than that of group II [38.8 (12.4), p = 0.014]. Sex (p = 0.23) and co-morbidity (hypertension, p = 0.34; diabetes, p = 0.13) did not differ between the patients in groups I and II. No differences were observed regarding important presenting symptoms, including fever (p = 0.72), cough (p = 0.69), and respiratory distress (p = 0.09). There was no significant difference in the median duration of symptoms in the two group (12 days), and conversion to the next level of severity was observed in 26 (20.6%) and 36 patients (13.8%) in group I and II, respectively. However, persistent positivity of RT-PCR at 14 days of initial positivity was more frequent among the patients in group I [24 (19%)] than among those in group II [29 (11.1%)]. Conclusions The prevalence of blood group A was higher among COVID-19 patients. Although ABO blood groups were not associated with the presentation or recovery period of COVID-19, patients with blood group A had delayed seroconversion.

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Assessing ABO/Rh Blood Group Frequency and Association with Asymptomatic Malaria among Blood Donors Attending Arba Minch Blood Bank, South Ethiopia

Malaria Research and Treatment ◽

10.1155/2016/8043768 ◽

2016 ◽

Vol 2016 ◽

pp. 1-7 ◽

Cited By ~ 2

Author(s):

Getaneh Alemu ◽

Mohammedaman Mama

Keyword(s):

Blood Group ◽

Malaria Infection ◽

Blood Donors ◽

Blood Groups ◽

High Rate ◽

Abo Blood Group ◽

Asymptomatic Malaria ◽

Abo Blood Groups ◽

Group Frequency ◽

Rh Blood Group

Background. Determination of the various ABO/Rh blood group distributions and their association with malaria infection has paramount importance in the context of transfusion medicine and malaria control. Methods. Facility based cross-sectional study was conducted from February to June, 2015, to assess ABO/Rh blood groups distribution and their association with asymptomatic malaria. A structured questionnaire was used to collect data. Blood grouping was done using monoclonal antibodies. Thin and thick blood films were examined for Plasmodium parasites. Data were analyzed using SPSS version 20.0. Results. A total of 416 blood donors participated with median age of 22±0.29 (median ± standard error of the mean). Distribution of ABO phenotypes, in decreasing order, was O (175, 42.1%), A (136, 32.7%), B (87, 20.9%), and AB (18, 4.3%). Most of them were Rh+ (386, 92.8%). The overall malaria prevalence was 4.1% (17/416). ABO blood group is significantly associated with malaria infection (P=0.022). High rate of parasitemia was seen in blood group O donors (6.899, P=0.003) compared to those with other ABO blood groups. Conclusion. Blood groups O and AB phenotypes are the most and the least ABO blood groups, respectively. There is significant association between ABO blood group and asymptomatic malaria parasitemia.

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The association between blood groups and maxillofacial deformities

Indian Journal of Plastic Surgery ◽

10.1055/s-0039-1699254 ◽

2008 ◽

Vol 41 (02) ◽

pp. 138-140

Author(s):

Rasoul Gheisari ◽

Mehdi Ghoreishian ◽

Movahedian Bijan ◽

Roozbehi Amrolah

Keyword(s):

Blood Group ◽

Blood Groups ◽

Iranian Population ◽

The Other ◽

Chi Square ◽

Genetic Characteristics ◽

Blood Group A ◽

Group A ◽

Group B ◽

Group Distribution

ABSTRACT Background: Blood group is a genetic characteristic which is associated with some diseases and deformities. Multifactorial characteristics of facial development make it difficult to predict a genetic pattern in a specific maxillofacial deformity, but epidemiological evaluations can reveal relationships between such deformities and some genetic characteristics or accompanied diseases, and this will help to recognise and treat them. The aim of this study is evaluation of the relationship between blood groups and maxillofacial deformities. Materials and Methods: In this study, blood groups of 190 patients with maxillofacial deformities who had had orthognathic surgery in Alzahra hospital, Isfahan, were compared with the general Iranian population. Results: Among 190 patients, 93 cases (49%) were men and 97 cases (51%) were women. Fifteen cases (8%) were < 20 years old, 130 cases (68%) were 20-30 years old, and the others (45 cases, 24%) were > 30 years old. The blood group distribution in our samples was as follows: blood group O = 76 cases (40%), blood group A = 58 cases (30%), blood group B = 41 cases (22%), and blood group AB = 15 cases (8%). Among these patients, 31 cases (16%) had maxillary deformities and 27 cases (14%) suffered from mandibular deformities while the other 132 cases (70%) had bimaxillary problems. The Chi-square test showed statistically significant differences between the blood group distribution of the patients of this study and the normal Iranian population ( P < 0.001). Conclusion: It was shown that among different blood groups; those with blood group B have a greater likelihood of association with maxillofacial deformities. On the other hand, the probability of the association of such deformities was the least with blood group A.

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Cardiovascular disease and ABO blood-groups in Africans. Are blood-group A individuals at higher risk of ischemic disease?: A pilot study

The Egyptian Heart Journal ◽

10.1016/j.ehj.2017.03.002 ◽

2017 ◽

Vol 69 (4) ◽

pp. 229-234 ◽

Cited By ~ 3

Author(s):

Djibril Marie BA ◽

Mamadou Saidou Sow ◽

Aminata Diack ◽

Khadidiatou Dia ◽

Mouhamed Cherif Mboup ◽

...

Keyword(s):

Cardiovascular Disease ◽

Pilot Study ◽

Blood Group ◽

Blood Groups ◽

Abo Blood Groups ◽

Ischemic Disease ◽

Blood Group A ◽

Group A

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Frequency of ABO and Rhesus blood groups in Saudi healthy blood donors versus non-Saudi in a retrospective study in Makkah City

Saudi Medical Horizons Journal ◽

10.54293/smhj.v1i1.16 ◽

2021 ◽

Vol 1 (1) ◽

pp. 2-13

Author(s):

Amal z. Moustafa ◽

Mohammed S. Aldosari ◽

Talat A. AL-Bukhari ◽

Younis A. Allohibi ◽

Shirin H . Teama ◽

...

Keyword(s):

Retrospective Study ◽

Blood Group ◽

Blood Donors ◽

Blood Groups ◽

Abo Blood Group ◽

Sri Lankan ◽

Blood Storage ◽

Blood Group A ◽

Group A ◽

Makkah City

Purpose: to assess the frequency of ABO and Rh blood groups among Saudi and non-Saudi healthy blood donors and to compare between them. Methods: A retrospective study was conducted; in Makkah City, Saudi Arabia. It included 15,365 participants of 44 nationalities who have attended the blood bank of King Abdul Aziz Hospital. The collected data were age, sex, nationality, ABO, and Rhesus blood groups. Results: 46.8 % of the participants were O, 28.8 % A, 19.5 % B, and 4.9% AB. The nationalities with a higher frequency of blood group O were Saudi, Mauritanian, Yemeni, Thai, Malian, Sudanese, Jordanian, Indian, Moroccan, Somali, Malaysian, Indonesian, Myanmar, Nigerian, Pakistani, Bangladeshi, Algerian, Djibouti, Burkinabe, Eritrean, Ghanaian, Bahraini, Bosnian, Canadian, Gambian, Iraqi, and Sri Lankan. Those with a higher frequency of blood group A were Turkish, Palestinian, Syrian, Lebanese, Egyptian, Afghan, Chadian, French, Tunisian, Cameroonian, Ethiopian, and British. Those with a higher frequency of B were Nigerien, American, Nepalese, and two nationalities with higher AB frequency Filipino and Chinese. 91.6 % of all populations were Rh-positive, and 8.4% were Rh-negative. The Saudi participants were like some nationalities and differed from others. Conclusion: In Makkah city, the higher frequency of ABO blood group in Saudi and non -Saudi people is O followed by A, then B, and AB. The Rh-positive is predominant, and 8.4% of the participants are negative. The ABO and Rh blood groups' identifications are essential for providing suitable blood storage for individuals in need.

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Dermatophytosis: association between ABO blood groups and reactivity to the trichophytin

Revista do Instituto de Medicina Tropical de São Paulo ◽

10.1590/s0036-46651999000500004 ◽

1999 ◽

Vol 41 (5) ◽

pp. 285-289 ◽

Cited By ~ 1

Author(s):

Fátima Regina VILANI-MORENO ◽

Maria Sueli Parreira de ARRUDA ◽

Simone Guadgnucci CLARO ◽

Elaine Valim Camarinha MARCOS ◽

Somei URA

Keyword(s):

Immune Response ◽

Blood Group ◽

Cellular Immune Response ◽

Blood Groups ◽

Abo Blood Groups ◽

Blood Group A ◽

Number Of Patients ◽

Group A ◽

Group B ◽

Cellular Immune

The authors investigated the relationship between dermatophytosis and ABO blood groups through blood typing, identification of isolated dermatophytes and specific cellular immune response of 40 individuals carriers of this mycosis. They verified that the fungus Trichophyton rubrum, isolated from 54.5% of the patients, was more frequent in individuals belonging to blood group A. The cellular immune response, evaluated through the trichophytin antigen, was positive in 25% of the studied patients; the presence of immediate reactions (30 minutes) was verified in 35%. The blood group distribution among patients with dermatophytosis and control groups was, respectively: 47.5% X 36% in group A, 40% X 50% in group O, 12.5% X 11% in group B. Even though the authors have found a higher number of patients belonging to blood group A infected by T. rubrum, these results suggest that there is no statistical evidence that these individuals are more susceptible to dermatophytosis.

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Association of ABO Blood Groups with Incidence of renal Lithiasis

Acta geneticae medicae et gemellologiae ◽

10.1017/s1120962300015778 ◽

1964 ◽

Vol 13 (2) ◽

pp. 167-172 ◽

Cited By ~ 1

Author(s):

Swadesh Anand

Keyword(s):

Blood Group ◽

Blood Groups ◽

Degree Of Freedom ◽

Abo Blood Groups ◽

Renal Lithiasis ◽

Blood Group A ◽

Group A ◽

The Difference

SUMMARY187 patients suffering from renal lithiasis have been examined to find out an association with ABO blood groups. It has been found that the incidence of Renal Lithiasis is comparatively higher in the patients of blood group A than in those of blood group O. The difference in percentage ratios A/(A+0)% in patients and controls is 17.96; the χ2 17.4331 for one degree of freedom shows that it differs from unity significantly. The frequencies of renal lithiasis in persons of blood group A against those of B, O and AB are 1.91, 1.59 and 1.31 respectively.

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