scholarly journals A Systematic Review on the Efficacy of Vaporized Hydrogen Peroxide as a Non-Contact Decontamination System for Pathogens Associated with the Dental Environment

Author(s):  
Rukshana Ahmed ◽  
Riaan Mulder

Aerosol generation and a wide range of pathogens originating from the oral cavity of the patient contaminate various surfaces of the dental clinic. The aim was to determine the efficacy of vaporized hydrogen peroxide fogging on pathogens related to the dental environment and its possible application in dentistry. PICOS statement (Population, Intervention, Comparison/Control, Outcome and Study design statement) was used in the review. Six electronic databases were searched for articles published from 2010 to 2020. Articles written in English reporting vaporized hydrogen peroxide on pathogens deemed to be relevant to the dental environment were assessed. The quality of the studies was assessed using the risk-of-bias assessment tool designed for the investigation of vaporized hydrogen peroxide application in dentistry. A total of 17 studies were included in the qualitative synthesis. The most commonly reported single bacterial pathogen was Methicillin-resistant Staphylococcus aureus in five studies, and the viruses Feline calicivirus, Human norovirus, and Murine norovirus were featured in three studies. The results of the studies reporting the log kill were sufficient for all authors to conclude that vaporized hydrogen peroxide generation was effective for the assessed pathogens. The studies that assessed aerosolized hydrogen peroxide found a greater log kill with the use of vaporized hydrogen peroxide generators. The overarching conclusion was that hydrogen peroxide delivered as vaporized hydrogen peroxide was an effective method to achieve large levels of log kill on the assessed pathogens. The hydrogen peroxide vapor generators can play a role in dental bio-decontamination. The parameters must be standardized and the efficacy assessed to perform bio-decontamination for the whole clinic. For vaporized hydrogen peroxide generators to be included in the dental bio-decontamination regimen, certain criteria should be met. These include the standardization and efficacy assessment of the vaporized hydrogen peroxide generators in dental clinics.

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Spyridoula Vazou ◽  
Collin A. Webster ◽  
Gregory Stewart ◽  
Priscila Candal ◽  
Cate A. Egan ◽  
...  

Abstract Background/Objective Movement integration (MI) involves infusing physical activity into normal classroom time. A wide range of MI interventions have succeeded in increasing children’s participation in physical activity. However, no previous research has attempted to unpack the various MI intervention approaches. Therefore, this study aimed to systematically review, qualitatively analyze, and develop a typology of MI interventions conducted in primary/elementary school settings. Subjects/Methods Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed to identify published MI interventions. Irrelevant records were removed first by title, then by abstract, and finally by full texts of articles, resulting in 72 studies being retained for qualitative analysis. A deductive approach, using previous MI research as an a priori analytic framework, alongside inductive techniques were used to analyze the data. Results Four types of MI interventions were identified and labeled based on their design: student-driven, teacher-driven, researcher-teacher collaboration, and researcher-driven. Each type was further refined based on the MI strategies (movement breaks, active lessons, other: opening activity, transitions, reward, awareness), the level of intrapersonal and institutional support (training, resources), and the delivery (dose, intensity, type, fidelity). Nearly half of the interventions were researcher-driven, which may undermine the sustainability of MI as a routine practice by teachers in schools. An imbalance is evident on the MI strategies, with transitions, opening and awareness activities, and rewards being limitedly studied. Delivery should be further examined with a strong focus on reporting fidelity. Conclusions There are distinct approaches that are most often employed to promote the use of MI and these approaches may often lack a minimum standard for reporting MI intervention details. This typology may be useful to effectively translate the evidence into practice in real-life settings to better understand and study MI interventions.


Neurosurgery ◽  
2021 ◽  
Author(s):  
David Bailey ◽  
Elias B Rizk

Abstract Hydrogen peroxide (H2O2) is a chemical with a wide range of applications. This includes its use in the medical field, in which its use has been ubiquitous but is most useful as an antiseptic and in achieving hemostasis. Neurosurgeons have been using H2O2 for well over a century, primarily for its hemostatic and antiseptic effects. This is in spite of the fact that the actual effectiveness of H2O2 as an antiseptic is questionable, and its use, in general, may be more dangerous than it appears. We review the application of H2O2 in medicine generally and, more specifically, in neurosurgery. This review outlines the reasoning behind the use of H2O2 as an antiseptic and details why it may not be as effective as one might think. We also detail its use as a hemostatic agent in neurosurgery, reviewing a number of techniques in which it has been useful in this role. Finally, we review the documented cases of complications associated with the use of H2O2 in neurosurgery. Ultimately, we conclude that the use of H2O2 in neurosurgery be reconsidered because of its lack of effectiveness as an antiseptic and potentially fatal complications.


ACS Catalysis ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 2454-2459
Author(s):  
Zhe Wang ◽  
Qin-Kun Li ◽  
Chenhao Zhang ◽  
Zhihua Cheng ◽  
Weiyin Chen ◽  
...  

Redox Biology ◽  
2021 ◽  
Vol 43 ◽  
pp. 101980
Author(s):  
Andree G. Pearson ◽  
Juliet M. Pullar ◽  
John Cook ◽  
Emma S. Spencer ◽  
Margreet CM. Vissers ◽  
...  

Nanomaterials ◽  
2019 ◽  
Vol 9 (11) ◽  
pp. 1525
Author(s):  
Sergey Vorobyev ◽  
Elena Vishnyakova ◽  
Maxim Likhatski ◽  
Alexander Romanchenko ◽  
Ivan Nemtsev ◽  
...  

Carey Lea silver hydrosol is a rare example of very concentrated colloidal solutions produced with citrate as only protective ligands, and prospective for a wide range of applications, whose properties have been insufficiently studied up to now. Herein, the reactivity of the immobilized silver nanoparticles toward oxidation, sulfidation, and sintering upon their interaction with hydrogen peroxide, sulfide ions, and chlorocomplexes of Au(III), Pd(II), and Pt(IV) was investigated using SEM and X-ray photoelectron spectroscopy (XPS). The reactions decreased the number of carboxylic groups of the citrate-derived capping and promoted coalescence of 7 nm Ag NPs into about 40 nm ones, excluding the interaction with hydrogen peroxide. The increased nanoparticles form loose submicrometer aggregates in the case of sulfide treatment, raspberry-like micrometer porous particles in the media containing Pd(II) chloride, and densely sintered particles in the reaction with inert H2PtCl6 complexes, probably via the formation of surface Ag-Pt alloys. The exposure of Ag NPs to HAuCl4 solution produced compact Ag films along with nanocrystals of Au metal and minor Ag and AgCl. The results are promising for chemical ambient temperature sintering and rendering silver-based nanomaterials, for example, for flexible electronics, catalysis, and other applications.


2003 ◽  
Vol 279 (3) ◽  
pp. 1665-1675 ◽  
Author(s):  
Juan A. Rosado ◽  
Pedro C. Redondo ◽  
Ginés M. Salido ◽  
Emilio Gómez-Arteta ◽  
Stewart O. Sage ◽  
...  

2012 ◽  
Vol 16 (11) ◽  
pp. 4483-4498 ◽  
Author(s):  
M. Yaeger ◽  
E. Coopersmith ◽  
S. Ye ◽  
L. Cheng ◽  
A. Viglione ◽  
...  

Abstract. The paper reports on a four-pronged study of the physical controls on regional patterns of the flow duration curve (FDC). This involved a comparative analysis of long-term continuous data from nearly 200 catchments around the US, encompassing a wide range of climates, geology, and ecology. The analysis was done from three different perspectives – statistical analysis, process-based modeling, and data-based classification – followed by a synthesis, which is the focus of this paper. Streamflow data were separated into fast and slow flow responses, and associated signatures, and both total flow and its components were analyzed to generate patterns. Regional patterns emerged in all aspects of the study. The mixed gamma distribution described well the shape of the FDC; regression analysis indicated that certain climate and catchment properties were first-order controls on the shape of the FDC. In order to understand the spatial patterns revealed by the statistical study, and guided by the hypothesis that the middle portion of the FDC is a function of the regime curve (RC, mean within-year variation of flow), we set out to classify these catchments, both empirically and through process-based modeling, in terms of their regime behavior. The classification analysis showed that climate seasonality and aridity, either directly (empirical classes) or through phenology (vegetation processes), were the dominant controls on the RC. Quantitative synthesis of these results determined that these classes were indeed related to the FDC through its slope and related statistical parameters. Qualitative synthesis revealed much diversity in the shapes of the FDCs even within each climate-based homogeneous class, especially in the low-flow tails, suggesting that catchment properties may have become the dominant controls. Thus, while the middle portion of the FDC contains the average response of the catchment, and is mainly controlled by climate, the tails of the FDC, notably the low-flow tails, are mainly controlled by catchment properties such as geology and soils. The regime behavior explains only part of the FDC; to gain a deeper understanding of the physical controls on the FDC, these extremes must be analyzed as well. Thus, to completely separate the climate controls from the catchment controls, the roles of catchment properties such as soils, geology, topography etc. must be explored in detail.


1991 ◽  
Vol 18 (2) ◽  
pp. 133-143 ◽  
Author(s):  
Hiroshi Ogasawara ◽  
Shiro Yoshimura ◽  
Takeo Kumoi

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