scholarly journals The Association of Upper Body Obesity with Insulin Resistance in the Newfoundland Population

Author(s):  
Sherif Youssef ◽  
Matthew Nelder ◽  
Guang Sun

Body-fat distribution is a primary risk factor for insulin resistance and cardiovascular disease. Visceral fat explains only a portion of this risk. The link between upper-body fat and insulin resistance is uncertain. Furthermore, upper-body fat is not clearly defined. Dual-energy X-ray absorptiometry (DXA) can accurately quantify body fat. In this study, we explored the relationship between non-visceral upper-body adiposity and insulin resistance and other markers of metabolic syndrome. Fat proportions in the upper body, leg, and visceral regions were quantified by using DXA in 2547 adult Newfoundlanders aged 19 and older. Adjusting for remaining fat regions, we performed partial correlation analysis for each body region and insulin resistance defined by the Homeostatic Model of Assessment (HOMA). Similarly, partial correlation analysis was also performed between each fat region and other markers of metabolic syndrome, including high-density lipoprotein cholesterol (HDL), triglycerides (TG), body mass index (BMI), and blood pressure. Major confounding factors, including age, caloric intake, and physical activity, were statistically controlled by using partial correlation analysis. Interactions between sex, menopausal status, and medication status were also tested. Arm adiposity was correlated with HOMA-IR (R = 0.132, p < 0.001) and HOMA-β (R = 0.134, p < 0.001). Visceral adiposity was correlated with HOMA-IR (R = 0.230, p < 0.001) and HOMA-β (R = 0.160, p < 0.001). No significant correlation between non-visceral trunk adiposity and insulin resistance was found. Non-visceral trunk adiposity was negatively correlated with HDL in men (R = −0.110, p < 0.001) and women (R = −0.117, p < 0.001). Non-visceral trunk adiposity was correlated with TG (total: R = 0.079, p < 0.001; men: R = 0.105, p = 0.012; women: R = 0.078, p = 0.001). In menopausal women, leg adiposity was negatively correlated with HOMA-IR (R = −0.196, p < 0.001) and HOMA-β (R = −0.101, p = 0.012). Upper-body adiposity in the arms is an independent contributor to insulin resistance. Upper-body adiposity in the non-visceral trunk region is an independent contributor to metabolic syndrome. Leg adiposity is protective against metabolic syndrome in women.

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Lingshu Wang ◽  
Jun Song ◽  
Chuan Wang ◽  
Peng Lin ◽  
Kai Liang ◽  
...  

Betatrophin and irisin are two recently identified hormones which may participate in regulating pancreaticβ-cell function. However, the associations of these two hormones withβ-cell function remain unclear. The present study aims to demonstrate the associations of circulating betatrophin and irisin levels withβ-cell function, assessed by the area under the curve (AUC) of C-peptide, and the possible correlation between these two hormones in previously diagnosed type 2 diabetes mellitus (T2DM) patients. In total, 20 age-, sex-, and body mass index- (BMI-) matched normal glucose tolerance (NGT) subjects and 120 previously diagnosed T2DM patients were included in this study. Partial correlation analysis was used to evaluate the relationships between these two hormones and indexes ofβ-cell function and insulin resistance. Our results showed that betatrophin levels were significantly elevated, while irisin levels were significantly decreased, in patients with T2DM compared with NGT subjects. However, partial correlation analysis showed that betatrophin levels did not correlate withβ-cell function-related variables or insulin resistance-related variables before or after controlling multiple covariates, while irisin correlated positively with insulin sensitivity but is not associated withβ-cell function-related variables. Besides, no correlation was observed between betatrophin and irisin levels. Hence we concluded that betatrophin and irisin were not associated withβ-cell function in previously diagnosed T2DM patients.


Foods ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 86
Author(s):  
So-Ra Yoon ◽  
Yun-Mi Dang ◽  
Su-Yeon Kim ◽  
Su-Yeon You ◽  
Mina K. Kim ◽  
...  

Capsaicinoid content, among other factors, affects the perception of spiciness of commercial kimchi. Here, we investigated whether the physicochemical properties of kimchi affect the spicy taste of capsaicinoids perceived by the tasting. High-performance liquid chromatography (HPLC) was used to evaluate the capsaicinoid content (mg/kg) of thirteen types of commercial kimchi. The physicochemical properties such as pH, titratable acidity, salinity, free sugar content, and free amino acid content were evaluated, and the spicy strength grade was determined by selected panel to analyze the correlation between these properties. Panels were trained for 48 h prior to actual evaluation by panel leaders trained for over 1000 h according to the SpectrumTM method. Partial correlation analysis was performed to examine other candidate parameters that interfere with the sensory evaluation of spiciness and capsaicinoid content. To express the specific variance after eliminating the effects of other variables, partial correlations were used to estimate the relationships between two variables. We observed a strong correlation between spiciness intensity ratings and capsaicinoid content, with a Pearson’s correlation coefficient of 0.78 at p ≤ 0.001. However, other specific variables may have influenced the relationship between spiciness intensity and total capsaicinoid content. Partial correlation analysis indicated that the free sugar content most strongly affected the relationship between spiciness intensity and capsaicinoid content, showing the largest first-order partial correlation coefficient (rxy/z: 0.091, p ≤ 0.01).


Author(s):  
Mizanur Rahman ◽  
Mahmuda Islam ◽  
Mehedi Hasan Shimanto ◽  
Jannatul Ferdous ◽  
Abdullah Al-Nur Shanto Rahman ◽  
...  

We performed a global analysis with data from 149 countries to test whether temperature can explain the spatial variability of the spread rate and mortality of COVID-19 at the global scale. We performed partial correlation analysis and linear mixed effect modelling to evaluate the association of the spread rate and motility of COVID-19 with maximum, minimum, average temperatures and temperature extreme (difference between maximum and minimum temperature) and other environmental and socioeconomic parameters. After controlling the effect of the duration after the first positive case, partial correlation analysis revealed that temperature was not related with the spatial variability of the spread rate of COVID-19. Mortality was negatively related with temperature in the countries with high-income economies. In contrast, temperature extreme was significantly and positively correlated with mortality in the low-and middle-income countries. Taking the country heterogeneity into account, mixed effect modelling revealed that inclusion of temperature as a fixed effect in the model significantly improved model skill predicting mortality in the low-and middle-income countries. Our analysis suggest that warm climate may reduce the mortality rate in high-income economies but in low and middle-income countries temperature extreme may increase the mortality risk.


1994 ◽  
Vol 58 (393) ◽  
pp. 533-541 ◽  
Author(s):  
J. T. Temple ◽  
J. N. Walsh

AbstractRelative concentrations of elements in the minerals of fine-grained sediments can be inferred from element-mineral correlation coefficients. The technique is applied to the distribution of REE in Middle Ordovician shales from South Wales analysed by ICPAES, Leco C/S125 and XRD. Phosphate and chlorite show mid-REE enrichment; muscovite + biotite shows mid-REE depletion. The complementarity of the chlorite and muscovite + biotite patterns may be due to fractionation during diagenetic recrystallisation. Partial correlation analysis is used to infer the presence of zircon.


2014 ◽  
Vol 625 ◽  
pp. 398-401
Author(s):  
Nur Hidayah Kamal Iqbal ◽  
Nooryusmiza Yusoff ◽  
Lemma Dendena Tufa

Partial correlation analysis is used in detecting the model-plant mismatch as it will give accurate location of mismatched submodel. In this work of model parameter mismatch detection in closed-loop system, a simplified method of partial correlation analysis is proposed. In this method, the identification step for input sensitivities relating setpoints and manipulated variables,Sru, is omitted due the ability of ARX model structure to capture the dynamic of the input-output data even though in the presence of unmeasured disturbance in closed-loop system. The ARX model structure is implemented in decorrelating the observed data from the correlated inputs. By using the ARX model, the mismatch is detected at the precise location compared to the detection using FIR decorrelation model.


TAMAN VOKASI ◽  
2017 ◽  
Vol 5 (1) ◽  
pp. 46
Author(s):  
Rizal Ardianto ◽  
Slamet Priyanto

The aims of this study is to find out; (1) the correlation between the type of job information, socio-economic status of parents and the practice facilities with a working interest (X1); (2) the correlation between the type of job information with the working interest (X2); (3) the correlation between socio-economic status of parents with working interests (X3); and (4) the correlation between practice facilities with a working interest of students of class XII Automotive Engineering Program SMK Negeri 2 Bima 2015/2016 academic year (Y).The research was conducted at SMK Negeri 2 Bima. The research was conducted in the first semester of the 2015/2016 academic year. The population in this study are 127 students taken from all of the students of class XII Automotive Engineering Expertise program. This study used applied try out technique. This research is a Ex Post Facto research. Data collection technique used a questionnaire method. Data analysis techniques used trials using multiple correlation analysis and partial correlation analysis.Based on the data analysis obtained the following results: (1) the results of the analysis of multiple correlation obtained coefficient rhitung 0433 and Fhitung 5629> Ftable 3:32 so it can be concluded that simultaneous correlation exists a positive and significant correlation between information type of work (X1) socioeconomic status (X2) and the practice facilities (X3) with working interests (Y); (2) the results of partial correlation analysis obtained rhitung 0312> rtabel 0176 so it can be concluded that there is a positive and significant correlation between the information type of work with work interests; (3) the results of partial correlation analysis obtained rhitung 0305> rtabel 0176 so it can be concluded that there is a positive and significant correlation between socio-economic status of parents with working interests; and (4) the results of partial correlation analysis obtained rhitung 0.244> 0.176 rtabel so it can be concluded that there is a positive and significant correlation between the practice facilities with a working interest of students of class XII Automotive Engineering Program SMK Negeri 2 Bima the academic year 2015/2016


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