scholarly journals Gender Differences in Depression and Quality of Life in Current and Abstinent Ketamine Users

2021 ◽  
Vol 18 (18) ◽  
pp. 9567
Author(s):  
Peng-Wei Wang ◽  
Cheng-Fang Yen ◽  
Hung-Chi Wu ◽  
Chih-Yao Hsu ◽  
Yu-Yi Yang
Keyword(s):  
Quality Of Life ◽  
Gender Differences ◽  
Demographic Data ◽  
Severe Depression ◽  
Healthy Controls ◽  
Moderator Analysis ◽  
The Past ◽  
Severity Of Depression

Ketamine use has become of increasing concern because it has spread in many parts of the world during the past few years. Substance users usually have depression and a lower quality of life (QoL). The aim of this study was to explore depression and QoL in ketamine users, and to further examine the role of gender in relation to differences in depression and QoL in ketamine users. This study recruited 204 current ketamine users, 102 abstinent ketamine users and 102 healthy controls. The demographic data, severity of depression and QoL were recorded. Analysis of Variance (ANOVA) was employed to compare the associations of ketamine use status with depression and QoL. Gender differences were examined by moderator analysis. The current ketamine users with and without ketamine use disorder, in addition to the abstinent ketamine users with ketamine use disorder, have more severe depression and a lower QoL than healthy controls. There were significant gender differences in depression and QoL in abstinent ketamine users with ketamine use disorder. Ketamine users have more severe depression and a lower QoL. In particular, depression and a lower QoL are still prominent in abstinent ketamine users. The gender differences in depression and QoL are significant in abstinent ketamine users.

Self-stigma and quality of life in Psychopharmacs treated outpatients with schizophrenia and related disorders - A cross-sectional study

2016 ◽  
Vol 33 (S1) ◽  
pp. s253-s254
Author(s):  
M. Holubova ◽  
J. Prasko ◽  
K. Latalova ◽  
M. Ociskova ◽  
A. Grambal ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Negative Impact ◽  
Demographic Data ◽  
The Self ◽  
Control Group ◽  
Healthy Controls ◽  
Schizophrenia Spectrum Disorders ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders

IntroductionSelf-stigma is a maladaptive psychosocial phenomenon that can disturb self-image and quality of life in psychiatric outpatients and may lead to dysphoria, social isolation and reduced adherence to treatment.ObjectivesSelf-stigma and QoL could be reflected as important factors for patients, who suffer from schizophrenia spectrum disorders, their caregivers and mental health specialists. Focus on reducing the self-stigma in supportive and educational therapy could be an important factor in promoting a higher QoL.AimsCurrent research moved attention to the relationship between demographic data, the severity of symptoms, self-stigma and quality of life in schizophrenic outpatients compared to the QoL in healthy controls.MethodsPatients who met ICD-10 criteria for schizophrenia spectrum disorder were recruited in the study. The Quality of Life Satisfaction and Enjoyment questionnaire (Q-LES-Q), Internalized Stigma of Mental Illness (ISMI) and severity of the disorder measured by objective and subjective Clinical Global Impression severity scales (CGI) were assessed.ResultsOne hundred and nine psychotic patients and 91 healthy controls participated in the study. Compared to the control group, there was a lower QoL and a higher score of self-stigma in psychotic patients. We found the correlation between the self-stigma, duration of disorder and QoL. The level of self-stigma correlated positively with total symptom severity score and negatively with the QoL. Stepwise regression analysis revealed that the objective severity and self-stigma score were significantly associated with the quality of life (Figure 2 and 3, Fig. 1).ConclusionsOur study suggests a negative impact of self-stigma level on the quality of life in patients suffering from schizophrenia spectrum disorders.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Gender differences in health-related quality of life among the elderly: The role of objective functional capacity and chronic conditions

2006 ◽  
Vol 63 (9) ◽  
pp. 2367-2380 ◽  
Author(s):  
Francesc Orfila ◽  
Montserrat Ferrer ◽  
Rosa Lamarca ◽  
Cristian Tebe ◽  
Antonia Domingo-Salvany ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gender Differences ◽  
Chronic Conditions ◽  
The Elderly ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Objective Functional

Review on immunosenescence

2007 ◽  
Vol 17 (3) ◽  
pp. 161-169 ◽  
Author(s):  
Lia Ginaldi ◽  
Lucia Paola Mengoli ◽  
Massimo De Martinis
Keyword(s):  
Quality Of Life ◽  
Morbidity And Mortality ◽  
Old People ◽  
The Past ◽  
Human Lifespan ◽  
Age Related ◽  
Consequent Reduction ◽  
General Improvement

The improvements of socio-environmental conditions, medical care and quality of life have caused a general improvement in the health status of the population and a consequent reduction of morbidity and mortality, resulting in an overall increased life-expectancy. The role of immunosenescence was negligible in the past, when the human lifespan was 40–50 years, and its impact on morbidity and mortality has emerged in combination with the extension of lifespan. Immunosenescence results from multifactorial processes that act on all components of the immune system. The changes associated with immunosenescence are playing an increasingly important role in the emergence of a series of age-related pathologies, conditioning the present epidemiology of old people.

scholarly journals In Chronic Spontaneous Urticaria, Comorbid Depression Linked to Higher Disease Activity, and Substance P Levels

2021 ◽  
Vol 12 ◽  
Author(s):  
Bachar Memet ◽  
Eren Vurgun ◽  
Fatma Barlas ◽  
Martin Metz ◽  
Marcus Maurer ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Substance P ◽  
Disease Activity ◽  
Chronic Spontaneous Urticaria ◽  
Healthy Controls ◽  
Comorbid Depression ◽  
Healthy Control ◽  
Severity Of Depression ◽  
Urticaria Activity Score

Background: Patients with chronic spontaneous urticaria often exhibit psychiatric comorbidities including depression that contribute to the impairment of their quality of life. How CSU and depression are linked isn't well-understood. Substance P has been shown to be increased in patients with CSU and is held to contribute to the pathogenesis of depression.Methods: We measured disease activity in 30 CSU patients without depression and 30 CSU patients with depression by using the urticaria activity score. The severity of depression was assessed with the Beck Depression Inventory. We measured SP levels in these patients as well as in 30 healthy control subjects. In patients with comorbid depression, we correlated SP levels with CSU disease activity and the severity of depression.Results: In CSU patients, disease activity and the severity of depression were positively linked. UAS7 values were higher in CSU patients with comorbid depression as compared to those without (p < 0.05). SP levels were higher in CSU patients with depression than in those without (p < 0.001), but was similar in all CSU patients compared to healthy controls. SP levels weren't correlated with UAS7 values in CSU patients with depression, whereas they were weakly but significantly correlated with BDI scores (p < 0.05).Conclusion: Our results suggest that, in CSU patients with comorbid depression, CSU disease activity affects the severity of depression. CSU patients with high disease activity should be explored for comorbid depression.

scholarly journals Expulsion from the Motherland: Association between Depression & Health-Related Quality of Life for Ethnic Rohingya Living with Refugee Status in Bangladesh

2020 ◽  
Vol 16 (1) ◽  
pp. 46-52
Author(s):  
K M Amran Hossain ◽  
Lori M. Walton ◽  
S. M. Yasir Arafat ◽  
Nidiorin Maybee ◽  
Rubel Hossen Sarker ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Severe Depression ◽  
Refugee Camps ◽  
Displaced Persons ◽  
Health Related Quality ◽  
Prevalence Of Depression ◽  
Related Quality ◽  
Health Related ◽  
Severity Of Depression

Background: The Rohingyas are an ethnic minority group from Myanmar who have experienced severe forms of violence such as murder, rape, humanitarian defilement and forcible expellation from their motherland. Exposure to trauma has a long-lasting impact on psychological well-being and Health-related Quality of Life (HRQoL). Objective: The purpose of this study was to examine the prevalence of depression and association with HRQoL for Rohingya displaced persons. Methodology: This was a prospective, cross-sectional study in two refugee camps in Southern Bangladesh, with a structured and language validated questionnaire. Results: The study indicates the prevalence of depression was 70% (n=150 respondents), with 8.7% reporting “severe depression” in PHQ-9. WHOQOL-BREF scores were inversely associated with symptoms on the depression scale with a strong and significant correlation (r= 0.652; p<0.01) in total and physical health; psychological (r= 0.757, p<0.01), social relationship (r= 0.479, p<0.01), environment (r= 0.443, p<0.01), increasing age (r= 0.272, p<0.01), severity of depression (r= 0.489, p<0.01). Furthermore, there was a statistically significant correlation with overall quality of life with same variables subsequently (r =0.600, 0.309, 0.482, 0.170, 0.103, 0.272, 0.339; p<0.01), also correlation was observed between married individuals and severity of depression in PHQ (r= 0.346), physical state (r= 0.353), psychological state (r= 0.358), and with social relationship (r= 0.435), with statistical significance (p= <0.01). Conclusion: There are higher incidence rates of moderate to severe depression than the population norms and low health-related quality of life than published population norms for Rohingya displaced persons living in refugee camps. Depression rates were inversely associated with HRQoL for Rohingya displaced persons living in refugee camps. Future research may consider the prevention of related medical issues for long term program implementation.

A Changing Islamist Order? From Civic Empowerment to Civic Regression—the Second Intifada and Beyond

2013 ◽  
Author(s):  
Sara Roy
Keyword(s):  
Quality Of Life ◽  
Social Institutions ◽  
The Political ◽  
The Past ◽  
Political Impact ◽  
Second Intifada ◽  
Political Economic ◽  
Islamist Movement

This chapter evaluates the political impact on the Islamist movement and its social institutions of the following: the second Intifada, Israel's 2005 “disengagement” from Gaza, Hamas' 2006 electoral victory, the subsequent international boycott of the Hamas-led government, and Hamas' June 2007 military takeover of Gaza. Particular consideration is given to how the role of social institutions changed after the second Intifada and after the 2006 elections. The chapter also shows how in the almost two decades since the Oslo process began, the quality of life in Palestine has declined markedly. The political, economic, and social possibilities of the past—both real and illusory—have since disappeared.

THE SEVERITY OF DEPRESSION IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN COMBINATION WITH ESSENTIAL HYPERTENSION

2020 ◽  
pp. 36-41
Author(s):  
Kochetova E.V.
Keyword(s):  
Quality Of Life ◽  
Essential Hypertension ◽  
Severe Depression ◽  
Chronic Obstructive ◽  
Study Group ◽  
Hypertensive Disease ◽  
Obstructive Pulmonary Disease ◽  
Severity Of Depression ◽  
Grade 3

The purpose of this study was to assess the severity of depression in patients with chronic obstructive pulmonary disease (COPD) with hypertensive disease. Research methods: patients with COPD in combination with hypertensive disease (n = 41) were studied. The study group consisted of patients with COPD with a long history of smoking. The study group was dominated by men (78.05%). The av-erage age of the patients was 64.51 ± 8.66 years. Research of function of external breath was studied with multimodular installation of type «Master-Lab/Jaeger». Exercise tolerance (6MWD, m), degree of dyspnea (MRC scale) were studied. The CAT test (COPD Assessment Test) was used to assess the state of health. Patients were asked to complete a Beck Depression Inventory. Results: Patients with grade 2 COPD accounted for 43.9%, with grade 3 COPD - 39.02%, with grade 4 COPD - 17.08%. Severe depression was diagnosed in 16.67% of patients with grade 2 COPD, in 37.50% of patients with grade 3 COPD and in 42.86% of patients with grade 4 COPD. Very Severe depression was noted in 28.57% of patients with grade 4 COPD. In 50% of patients with severe and very severe depression, a serious effect of COPD on the quality of life (21– 30 CAT points) was re-vealed, a very serious effect of COPD on the quality of life (31– 40 CAT points) was noted in 35.71% of patients. In general, in the group of COPD patients with essential hypertension, severe depression according to the Beck scale was found in 29.27%. Very severe depression was noted in 4.88% of pa-tients with COPD with essential hypertension.

scholarly journals PERAN KESEIMBANGAN PEKERJAAN-KELUARGA DAN KUALITAS HIDUP TERHADAP KEBAHAGIAAN KERJA PADA PETUGAS PEMASYARAKATAN PEREMPUAN

2019 ◽  
Vol 18 (1) ◽  
pp. 82
Author(s):  
Ika Zenita Ratnaningsih ◽  
Anggun Resdasari Prasetyo
Keyword(s):  
Quality Of Life ◽  
Correctional Officers ◽  
Demographic Data ◽  
Sampling Technique ◽  
Correctional Institutions ◽  
Family Balance ◽  
Work Family Balance ◽  
Work Family

Correctional officers encounter vulnerable working conditions that may cause psychological discomfort at work. This study aims to determine the role of work-family balance, and quality of life to happiness at work in female correctional officers. The subjects in this study were 87 female correctional officers from three correctional institutions in Semarang and Malang. The age of subjects ranged from 22 - 57 years (Mage = 41.80); and the work period of the subjects ranged from 3-34 years (Mtenure = 18.80). The sampling technique used was convenience sampling. Instruments that used for data collection were demographic data questionnaires, Work-Family Balance Scale (32 items; α = .898), WHOQOL-BREF Scale (26 items; α = .906), and Happiness at Work Scale (22 items; α = .801). Data analysis using multiple regression analysis show there a positive and significant correlation between work-family balance and happiness at work (r = .613; p <.001), there was a positive and significant correlation between quality of life and work happiness (r = .394; p <.001), furthermore work-family balance and quality of life together can predict happiness at work in female correctional officers (r = .633; R2 = .401; F = 28.115; p <.001). Work-family balance and quality of life effectively contributed 39.7%  to predicting happiness at work in female correctional officers.

What is the role of prophylaxis in the improvement of health-related quality of life of patients with hemophilia?

Hematology ◽  
2013 ◽  
Vol 2013 (1) ◽  
pp. 52-55 ◽  
Author(s):  
David Buchbinder ◽  
Margaret V. Ragni
Keyword(s):  
Quality Of Life ◽  
Health Related Quality ◽  
The Past ◽  
Related Quality ◽  
Health Related ◽  
History Of ◽  
Lost Time ◽  
The Impact

Abstract A 32-year-old male with severe hemophilia presents for his annual evaluation. He has a history of multiple joint bleeds that he has always treated on-demand, that is, after they occur. You have recommended prophylaxis, that is, preventively, before they occur, to decrease his episodes of bleeding; however, he had been reluctant to comply in the past. He is having difficulty keeping up at work because of interruptions, pain, and lost time at work. He is willing to consider a trial of prophylaxis. You discuss the impact of hemophilia on his health-related quality of life (HRQOL) and consider measuring his HRQOL over time using a generic measure of HRQOL to determine whether prophylaxis will reduce interruptions, pain, and lost time from work and improve his HRQOL.

scholarly journals Gender features of the influence of depressive and dissominal symptoms on the quality of life of patients with psoriasis

2021 ◽  
pp. 60-66
Author(s):  
N. S. Olshevskaya ◽  
N. A. Olshevsky ◽  
D. V. Prohorov ◽  
V. N. Klinkov ◽  
H. N. Primysheva ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gender Differences ◽  
Depressive Symptoms ◽  
Sleep Disorders ◽  
Sleep Disturbances ◽  
Rating Scale ◽  
Negative Effect ◽  
Severity Of Depression ◽  
Index Of Severity

Quality of life indicators (QL) of patients are widely used in dermatological practice, but the influence of depressive and dissomnic symptoms on QL of patients with gender differences is not sufficiently studied.Objective: to identify depressive and dissominal symptoms in patients with psoriasis and evaluate its impact on the quality of life of these patients taking into account gender differences.Materials and methods: 34 patients with psoriasis were examined. Clinical examination included: analysis of complaints, medical history, assessment of dermatological status. Diagnosis of the presence and severity of depression was performed using a PHQ-9 patient health rating scale. Dissominal symptoms in patients with psoriasis were determined using the index of severity of insomnia ISI. To assess the quality of life, a dermatological index of quality of life (DLQI) was used.Results and discussion. Sleep disorders were detected in 15 patients (44.1%), depressive symptoms were determined in all patients, a negative effect of the disease on the quality of life of patients was found in 32 people (94.1%).Correlation analysis of data from the entire population of patients revealed statistically significant correlations of DLQI with the severity of depressive symptoms (r = 0.45, p = 0.008) and sleep disorders (r = 0.35, p = 0.04). In women, DLQI significantly correlates with the severity of depression (r = 0.48, p = 0.04) and tends to be associated with sleep disturbances (r = 0.43, p = 0.07). In men, the relationship between DLQI and indicators of depression and sleep disturbances is significantly weaker and is not statistically significant ((r = 0.34, p = 0.22) and (r = 0.17, p = 0.55), respectively).Conclusion.depressive symptoms and sleep disorders are interrelated with the quality of life of patients with psoriasis, and this relationship is more pronounced in women. Consequently, it is advisable to include effects aimed at normalizing mood and sleep in the program of complex therapy of psoriasis, taking into account gender differences.

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