scholarly journals Blood Lead Levels and Cardiovascular Disease Risk: Results from the Korean National Health and Nutrition Examination Survey

2021 ◽  
Vol 18 (19) ◽  
pp. 10315
Author(s):  
Yoonjin Park ◽  
Jungjin Han
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Systolic Blood Pressure ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Total Cholesterol Level ◽  
Hdl Cholesterol ◽  
Blood Lead ◽  
Blood Lead Levels ◽  
Lead Levels

(1) Objective: Lead, a heavy metal that exists commonly in air, soil and crops may cause chronic disease in the cardiovascular system. The purpose of this study is to investigate how blood lead levels affect cardiovascular disease in adults. (2) Study Design and Participants: It is a cross-sectional, descriptive study using data from the Korean National Health and Nutrition Examination Survey (KNHANES). Data from a total of 1929 participants, derived from the KNHANES, conducted by the Korea Centers for Disease Control and Prevention, in 2017, were analyzed using SPSS version 25.0. (3) Measurement: The cardiovascular disease risk was calculated using the Framingham risk score. There was a strong positive correlation between blood lead levels and the Framingham risk score. Furthermore, of the FRS sub-criteria, systolic blood pressure, HDL cholesterol level and total cholesterol level all also showed a significant correlation. (4) Results: We analyzed the correlation between PbB levels and the FRS sub-criteria, including systolic blood pressure, HDL cholesterol level, total cholesterol level and the FRS total. We found a significant positive correlation between PbB levels and systolic blood pressure, FRS total and total cholesterol level (p < 0.05), as well as a significant negative correlation with HDL cholesterol level (p < 0.05). (5) Conclusion: Based on the perception that there is no lower toxicological threshold for blood lead, it is necessary to restrict lead in product manufacturing for the purpose of public health. In addition, it is necessary to be aware of the dangers of exposure to even small amounts of lead in daily life.

scholarly journals Correlation of Blood Lead Levels and Elevated Blood Pressure in Newly Detected Hypertensive Patients

2021 ◽  
Vol 10 (13) ◽  
pp. 941-946
Author(s):  
Shuaib Ahmed M. A ◽  
Raghav Sharma ◽  
Shama Prakash K
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Diastolic Blood Pressure ◽  
Lead Level ◽  
Blood Lead ◽  
Health Concern ◽  
Blood Lead Levels ◽  
P Value ◽  
Hypertensive Patients ◽  
Lead Levels

BACKGROUND Hypertension is one of the most common diseases all over the world. Lead is a common environmental and industrial pollutant with no beneficial biological role. The contribution of environmental lead exposure to hypertension is an important public health concern. The objective of this study was to determine the blood lead levels in hypertensive patients and to investigate the correlation between blood lead (B-Pb) levels and the values of blood pressure in hypertensive patients. METHODS This is a hospital based analytical cross-sectional study conducted over a period of one and half years. Subjects included 50 newly detected hypertensive and 50 healthy subjects recruited who were both age and sex matched. Mean of age, blood lead levels, systolic blood pressure (SBP), diastolic blood pressure (DBP) with standard deviation were assessed. Linear regression was used to estimate the predicted systolic blood pressure (BP) and diastolic BP with lead levels. Pearson correlation was used to estimate the correlation between blood lead and blood pressure levels. RESULTS In this study, 52 % of cases and controls were in the age group of 41 - 60 years. 22 % of the subjects were more than 61 years of age. 45 % of the total subjects were females and 55 % were males. 46 % of the controls and 44 % of the cases were females. Comparison of the serum lead levels (mcg / dl) between cases and controls showed that serum lead levels (mcg / dl) were higher in Cases group with a t-value of -7.38 and was statistically significant with a P-value of < 0.001. Comparison of the serum lead levels (mcg / dl) between the males and females showed that serum lead levels (mcg / dl) were higher in female group with a t-value of - 0.151 and was statistically non-significant with a P-value of 0.881. This study showed that there is an increase in blood lead levels in hypertensive patients compared to the control group. Stage 2 hypertension has higher serum lead level value of 21.228 compared to stage 1. Serum lead levels were higher in females compared to males. CONCLUSIONS Our study indicated that blood lead level is significantly and positively correlated to blood pressure among newly detected hypertensive patients. Increase in blood lead levels causes increase in both systolic and diastolic blood pressures. KEY WORDS Hypertension, Lead, Systolic Blood Pressure, Diastolic Blood Pressure

scholarly journals Correlation Between Total Cholesterol Level with Blood Pressure of Hypertensive Patients in Kalidoni, Palembang

2021 ◽  
pp. 207-212
Author(s):  
Tungki Pratama Umar ◽  
Mariana Mariana
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Total Cholesterol ◽  
Health Center ◽  
Cholesterol Level ◽  
Total Cholesterol Level ◽  
Blood Cholesterol ◽  
Primary Health Center ◽  
Hypertensive Patients ◽  
Primary Health

Background: Hypertension is the main problem worldwide. It has strong relationship with other component of metabolic syndrome, namely dyslipidemi. Authors are analyzing the correlation between total cholesterol level and blood pressure in the hypertensive patient at Kalidoni Primary Health Center, Palembang, Indonesia.Methods: This was a cross-sectional study involving 82 adult hypertensive patients. Data were collected from the medical record of patients who are visiting Kalidoni Primary Health Center in December 2019-January 2020. Demographic data, blood pressure, and total cholesterol level were gained. Obtained data are analyzed descriptively (frequency distribution) and analytically (correlation using Pearson or Spearman method).Result: Significant positive correlations were observed between total cholesterol level and systolic blood pressure (r=0.509, p=0.000) in addition to body weight and diastolic blood pressure (r=0.279; p=0.011).Conclusion: Blood cholesterol level had a significant correlation with moderate strength for determining systolic blood pressure level in hypertensive patients.

scholarly journals Risk Factors of Hypercholesterolemia on Obese Pre-elderly Population in Rejosari Sub-village Gunung Kidul Yogyakarta

2016 ◽  
Vol 3 (2) ◽  
pp. 92
Author(s):  
Desto Arisandi ◽  
Yesi Apriliasari ◽  
Subrata Tri Widada
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Total Cholesterol ◽  
Diastolic Blood Pressure ◽  
Cholesterol Level ◽  
Total Cholesterol Level ◽  
P Value ◽  
Spearman Correlation ◽  
Cell Recovery

Background: Obesity is one of the most epidemiological burden which is being a dangerous threat for global health. It also contributes for leading cause of hypercholesterolemia. Prevalence of stroke, diabetes mellitus, coronary heart disease, and hypertension in Indonesia has reached out 23.7% in 2007. Rejosari sub-village, Kemadang village, Tanjungsari sub-district locate in coastal area which is fisher taking mostly part of the citizen's occupation. Hence they have tendency to intake sea products such as shrimps, squids, crabs, anchovies, and  bivalves that contain amino acid required to growth and cell recovery nevertheless it also has much cholesterol contained which cause of total cholesterol level rising. The aims of this study to determine risk factors of hypercholesterolemia on obese pre-eldery population in Rejosari sub-village, Kemadang village, Tanjungsari sub-district, Gunung Kidul district, Yogyakarta. Method: This was an analytic observational study with cross sectional that conducted on February 2015 on obese pre-eldery population in Rejosari sub-village, Kemadang village, Tanjungsari sub-district, Gunung Kidul district, Yogyakarta. Data collected such age, sex, blood pressure, seafood intake frequencies, and total cholesterol. Data were analyzed by STATA version 12 software for windows with spearman correlation statistical test. Result: This study findings that 30 pre-elderly people came as respondents. Data  performed the average value of age was 49 years old, systolic blood pressure was 142 mmHg, diastolic blood pressure was 87 mmHg, seafood intake frequencies was 3 times per week, and total cholesterol level was 241 mg/dl. Spearman correlation shown age (p value=0.0477), systolic blood pressure (p value=0.0012), diasolic blood pressure (p value= 0.0435) and seafood intake frequencies (p value= 0.0018) have stattistical correlation with hypercholesterolemia. Conclusion:Age, systolic blood pressure, diastolic blood pressure, and seafood intake frequencies are correlated with total cholesterol raising within blood.

Pengaruh Pemberian Terapi Oksigen Hiperbarik Terhadap Kadar Kolesterol Total Pada Tikus Putih (Rattus novergicus) Jantan Galur Wistar Yang Di Induksi Diet Tinggi Lemak

2018 ◽  
Vol 16 (1) ◽  
pp. 1 ◽  
Author(s):  
AZRUL HILDAN SAFRIZAL
Keyword(s):  
Cardiovascular Disease ◽  
Total Cholesterol ◽  
Cholesterol Level ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
High Fat Diet ◽  
Oxygen Therapy ◽  
Total Cholesterol Level ◽  
High Fat ◽  
Cholesterol Levels

<p>The pattern and lifestyle of today's society with the presence of an interner facility makes people spend more time sitting out than on exercise and increased consumption of high-fat foods may increase the risk of cardiovascular disease. An effective therapy is needed in preventing the occurrence of cardiovascular disease. Hyperbaric oxygen now starts to develop for the treatment of several diseases, which in turn can increase the gene forming antioxidant enzymes and ROS. To determine effect of hyperbaric oxygen therapy on total cholesterol levels of wistar white rats (Rattusnovergicus) induced bye high fat. The study was carried out in an expeative post test only group control of three groups. One group is given standard feed. All groups induced high-fat diet and standard feed. Of the two groups induced, one group was given hyperbaric oxygen therapy with a dose of 3 x 30 minutes for six days on day 7 at a blood test to determine total cholesterol levels<strong>. </strong>One way Anova parametric statistic test showed that p = 0.007 &lt; α proved hypothesis that hyperbaric oxygen therapy giving effect to total cholesterol level of white mice of jantangalurist rings induced by high fat diet. Total cholesterol was significantly different between K (-) and K (+) and between K (-) and P. It was found that hyperbaric oxygen therapy had an effect on total cholesterol level dose of 3x30 minutes for six days.</p>

Stentul JJ ureteral - care este optiunea mai buna? New Considerations Regarding Chronic Kidney Disease, Cardiovascular Disease and Dyslipidemia in Diabetic Patients

2018 ◽  
Vol 69 (8) ◽  
pp. 2064-2066
Author(s):  
Mircea Munteanu ◽  
Adrian Apostol ◽  
Viviana Ivan
Keyword(s):  
Cardiovascular Disease ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Total Cholesterol ◽  
Total Cholesterol Level ◽  
Vascular Complications ◽  
Hdl Cholesterol ◽  
Controlled Study ◽  
Diabetic Patients ◽  
Artery Disease

The aim of the present study is to investigate the prevalance of chronic kidney disease (CKD), of cardiovascular disease (CVD) and dyslipidemia in patients with diabetes mellitus (DM). We conducted a prospective, controlled study involving 420 diabetic patients (120 T1DM, 300 T2DM) and investigate the following aspects: the presence of vascular complications (stroke, coronary artery disease, peripheral artery disease), lipid profile (total cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides), kidney function (glomerular filtration rate, albuminuria), blood pressure, HbA1C. The results that in diabetic patients with CKD there is an increased prevalence of CVD and of dislipidemia. Also we noticed a negative correlation between total cholesterol level and decease in eGFR in all patients, with or without CKD.

scholarly journals Blood lead level and risk of hypertension in the United States National Health and Nutrition Examination Survey 1999–2016

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Man Fung Tsoi ◽  
Chris Wai Hang Lo ◽  
Tommy Tsang Cheung ◽  
Bernard Man Yung Cheung
Keyword(s):  
Blood Pressure ◽  
Lead Exposure ◽  
Blood Lead Level ◽  
Lead Level ◽  
Blood Lead ◽  
The United States ◽  
Study Data ◽  
Blood Lead Levels ◽  
Environmental Lead ◽  
Lead Levels

AbstractLead is a heavy metal without a biological role. High level of lead exposure is known to be associated with hypertension, but the risk at low levels of exposure is uncertain. In this study, data from US NHANES 1999–2016 were analyzed. Adults with blood lead and blood pressure measurements, or self-reported hypertension diagnosis, were included. If not already diagnosed, hypertension was defined according to the AHA/ACC 2017 hypertension guideline. Results were analyzed using R statistics version 3.5.1 with sample weight adjustment. Logistic regression was used to study the association between blood lead level and hypertension. Odds ratio (OR) and 95% confidence interval (95% CI) were estimated. Altogether, 39,477 participants were included. Every doubling in blood lead level was associated with hypertension (OR [95%CI] 1.45 [1.40–1.50]), which remained significant after adjusting for demographics. Using quartile 1 as reference, higher blood lead levels were associated with increased adjusted odds of hypertension (Quartile 4 vs. Quartile 1: 1.22 [1.09–1.36]; Quartile 3 vs. Quartile 1: 1.15 [1.04–1.28]; Quartile 2 vs. Quartile 1: 1.14 [1.05–1.25]). In conclusion, blood lead level is associated with hypertension in the general population with blood lead levels below 5 µg/dL. Our findings suggest that reducing present levels of environmental lead exposure may bring cardiovascular benefits by reducing blood pressure.

Sign in / Sign up

Export Citation Format

Share Document