Dietary Heavy Metal Exposure among Finnish Adults in 2007 and in 2012

For the non-smoking and non-occupationally exposed population in Europe, food is the main source of heavy metal exposure. The aim of the study was to estimate the dietary exposure of the Finnish adult population to cadmium, lead, inorganic arsenic, inorganic mercury and methyl mercury as well as nickel using governmental as well as industry data on heavy metal occurrence in foodstuffs and the data from two national food consumption surveys conducted in 2007 and 2012. The sources of heavy metal exposure were estimated for the working-age population (25 to 64 years) and for the elderly (65 to 74 years). Exposure differences between years and between population groups were compared statistically. The mean exposure of women aged 25 to 45 years to cadmium and lead was statistically significantly (p < 0.001) higher, and the methyl mercury exposure lower (p = 0.001) than that of women aged 46 to 64 years. For nickel and inorganic arsenic the differences were lower but still statistically significant (p < 0.05). Between genders, significant difference (p < 0.05) was only seen for lead and nickel. Mean cadmium exposure was significantly higher in 2012 than in 2007. For at least 95% of the adult population, the risk of health damage from mercury or nickel exposure is negligible, but the margin of exposure for lead and inorganic arsenic is small and shows a possible risk of cancer or neurotoxic effects.

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Association between Pb, Cd, and Hg Exposure and Liver Injury among Korean Adults

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18136783 ◽

2021 ◽

Vol 18 (13) ◽

pp. 6783

Author(s):

Do-won Kim ◽

Jeongwon Ock ◽

Kyong-Whan Moon ◽

Choong-Hee Park

Keyword(s):

Heavy Metals ◽

Heavy Metal ◽

Liver Injury ◽

Liver Function ◽

Large Population ◽

Metal Exposure ◽

Gamma Glutamyl Transferase ◽

Heavy Metal Exposure ◽

Significant Difference ◽

Glutamyl Transferase

Background: Exposure to lead (Pb), cadmium (Cd), and mercury (Hg) has been reported to be associated with liver-related diseases. However, studies examining the association between heavy metal exposure and liver injury in a large population are scant and characterized by inconsistent results. This study aimed to evaluate the association between levels of heavy metal exposure and liver injury in the general population. Methods: Data for 2953 participants aged 19 years or more obtained from the Korean National Environmental Health Survey (KoNEHS) Cycle 3 (2015–2017) were used. The associations between levels of blood or urine heavy metals (Pb, Cd, and Hg) and liver function biomarkers [aspartate aminotransferase (AST), alanine aminotransferase (ALT), and gamma-glutamyl transferase (GGT)] were evaluated using multiple linear regression analysis. Results: Regarding the blood Pb (BPb), AST was higher in those of the 4th quartile, ALT was higher in those of the 2nd and 4th quartiles, and GGT was higher in those of the 3rd and 4th quartiles than in the 1st quartile. For urinary Cd (UCd), AST was higher in those of the 4th quartile; ALT was higher in those of the 2nd, 3rd, and 4th quartiles; and GGT was higher in the 4th quartile than in the 1st quartile. For the blood Hg (BHg), AST was higher in those of the 2nd and 4th quartile, ALT was higher in those of the 2nd, 3rd, and 4th quartiles; and GGT was higher in those of the 3rd and 4th quartiles than in the 1st quartile. There was no significant difference between urinary Hg (UHg) and liver function markers. Conclusion: Heavy metal exposure showed an association with liver injury among the general adult population in Korea. Further studies are required to clarify the relationship between heavy metals and liver injury.

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Bioaccessibility-corrected health risk of heavy metal exposure via shellfish consumption in coastal region of China

Environmental Pollution ◽

10.1016/j.envpol.2021.116529 ◽

2021 ◽

Vol 273 ◽

pp. 116529

Author(s):

Minwei Chai ◽

Ruili Li ◽

Yuan Gong ◽

Xiaoxue Shen ◽

Lingyun Yu

Keyword(s):

Heavy Metal ◽

Health Risk ◽

Coastal Region ◽

Metal Exposure ◽

Heavy Metal Exposure

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Relationship between heavy metal exposure and type 2 diabetes: a large-scale retrospective cohort study using occupational health examinations

BMJ Open ◽

10.1136/bmjopen-2020-039541 ◽

2021 ◽

Vol 11 (3) ◽

pp. e039541

Author(s):

Jun Ho Ji ◽

Mi Hyeon Jin ◽

Jung-Hun Kang ◽

Soon Il Lee ◽

Suee Lee ◽

...

Keyword(s):

Heavy Metals ◽

Type 2 Diabetes ◽

Heavy Metal ◽

Cohort Study ◽

Retrospective Cohort ◽

Metal Exposure ◽

Heavy Metal Exposure ◽

Lead And Cadmium

ObjectivesTo investigate the associations between heavy metal exposure and serum ferritin levels, physical measurements and type 2 diabetes mellitus (DM).DesignA retrospective cohort study.SettingChangwon, the location of this study, is a Korean representative industrial city. Data were obtained from medical check-ups between 2002 and 2018.ParticipantsA total of 34 814 male subjects were included. Of them, 1035 subjects with lead exposure, 200 subjects with cadmium exposure and the 33 579 remaining were assigned to cohort A, cohort B and the control cohort, respectively. Data including personal history of alcohol and smoking, age, height, weight, the follow-up duration, haemoglobin A1c (HbA1c), fasting blood sugar (FBS), ferritin levels, and lead and cadmium levels within 1 year after exposure were collected.Primary outcome measureIn subjects without diabetes, changes in FBS and HbA1c were analysed through repeated tests at intervals of 1 year or longer after the occupational exposure to heavy metals.ResultsIn Cohort A, DM was diagnosed in 33 subjects. There was a significant difference in lead concentrations between the subjects diagnosed with DM and those without DM during the follow-up period (3.94±2.92 mg/dL vs 2.81±2.03 mg/dL, p=0.002). Simple exposure to heavy metals (lead and cadmium) was not associated with DM in Cox regression models (lead exposure (HR) 1.01, 95% CI: 0.58 to 1.77, p 0.971; cadmium exposure HR 1.48, 95% CI: 0.61 to 3.55, p=0.385). Annual changes in FBS according to lead concentration at the beginning of exposure showed a positive correlation (r=0.072, p=0.032).ConclusionOur findings demonstrated that simple occupational exposure to heavy metals lead and cadmium was not associated with the incidence of DM. However, lead concentrations at the beginning of the exposure might be an indicator of DM and glucose elevations.

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Environmental Heavy Metal Exposure and Chronic Kidney Disease in the General Population

Journal of Korean Medical Science ◽

10.3346/jkms.2015.30.3.272 ◽

2015 ◽

Vol 30 (3) ◽

pp. 272 ◽

Cited By ~ 66

Author(s):

Nam Hee Kim ◽

Young Youl Hyun ◽

Kyu-Beck Lee ◽

Yoosoo Chang ◽

Seungho Rhu ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Heavy Metal ◽

Kidney Disease ◽

General Population ◽

Metal Exposure ◽

Heavy Metal Exposure

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Evaluation of heavy metal exposure pathways on children from an informal e-waste processing village in Viet Nam

Human and Ecological Risk Assessment An International Journal ◽

10.1080/10807039.2021.2000362 ◽

2021 ◽

pp. 1-17

Author(s):

Hien Thi Thu Ngo ◽

Pensri Watchalayann ◽

Diep Bich Nguyen ◽

Hai Ngoc Doan ◽

Li Liang

Keyword(s):

Heavy Metal ◽

Metal Exposure ◽

Viet Nam ◽

Waste Processing ◽

Heavy Metal Exposure ◽

Exposure Pathways

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Reproductive parameters as assessment tools for arsenic and chromium induced toxicity in Eudrilus eugeniae

Indian Journal of Agricultural Research ◽

10.18805/ijare.a-5009 ◽

2018 ◽

Author(s):

Shefali . ◽

Jyoti Yadav ◽

R.K. Gupta

Keyword(s):

Body Weight ◽

Adult Population ◽

Assessment Tools ◽

Time Dependent ◽

Metal Exposure ◽

Reproductive Parameters ◽

Eudrilus Eugeniae ◽

Heavy Metal Exposure ◽

Cocoon Production ◽

Emergence And Reduction

The present study of 28 days was carried out to assess the effect of arsenic and chromium on biomass gain and reproduction parameters (cocoon and hatchling production) of E. eugeniae. The worms were cultured in substrate having different concentrations of arsenic and chromium alongwith control in triplicates. Dose and time dependent decreased in number of adults, cocoon production and hatchling emergence and reduction in growth was observed. In worms exposed to Cr (0.1 ppm), reduction in population (24.66%), body weight (2.44%), cocoon production (47.14%) and hatchling emergence (39.99%) was observed. While As (0.1 ppm) exposure resulted in reduction of adult population (10.66%), body weight (0.24%), cocoon production (37.05%) and hatchling emergence (28.53%) was observed. Cocoon production was observed to be the most sensitive parameter for heavy metal exposure in all treatments. Chromium was observed to be more detrimental to earthworms when compared with arsenic.

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Prospective associations between environmental heavy metal exposure and renal outcomes in adults with chronic kidney disease

Nephrology ◽

10.1111/nep.13089 ◽

2018 ◽

Vol 23 (9) ◽

pp. 830-836 ◽

Cited By ~ 13

Author(s):

Chun-Chieh Tsai ◽

Chia-Lin Wu ◽

Chew-Teng Kor ◽

Ie-Bin Lian ◽

Chin-Hua Chang ◽

...

Keyword(s):

Chronic Kidney Disease ◽

Heavy Metal ◽

Kidney Disease ◽

Metal Exposure ◽

Heavy Metal Exposure ◽

Renal Outcomes

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Effect of Probiotic and Amla Powder Supplementation on Metabolic Profile and Milk Production of Summer Stressed Buffaloes Residing in Heavy Metal Polluted Areas of Ludhiana

Indian Journal of Animal Research ◽

10.18805/ijar.b-4270 ◽

2021 ◽

Author(s):

Pranesh V. Yeotikar ◽

Shashi Nayyar ◽

Chanchal Singh ◽

C.S. Mukhopadhyay ◽

Sandeep Sodhi Kakkar ◽

...

Keyword(s):

Oxidative Stress ◽

Heavy Metal ◽

Milk Production ◽

Metabolic Profile ◽

Antioxidant Status ◽

Live Cells ◽

Metal Exposure ◽

Heavy Metal Exposure ◽

Exposed Area ◽

Oral Supplementation

Background: Oxidative stress is a unified concept for the assessment of metabolic status of buffaloes affected by a cocktail of heavy metal exposure from environment and it may significantly affect the metabolic profile and milk production during summer season. The present study aimed at evaluation of effect of probiotic (Saccharomyces cerevisiae strain 1026) and amla powder (Embilica officinalis) supplementation on levels of heavy metals, antioxidant status, oxidative stress in lymphocytes, metabolic profile and milk production of summer stressed buffaloes exposed to environmental heavy metal pollution. Methods: Twenty summer stressed lactating Murrah buffaloes of the same age group, close parity and in early lactation from the heavy metal exposed area were divided into two groups: Control (without supplementation) and Treatment group (supplemented with Saccharomyces cerevisiae1026) @ 50 billion live cells / animal /day and Amla powder @ 86 mg/kg body weight for 30 days. Blood and milk samples were collected from both the groups on the day of starting of supplementation (i.e. day 0) and on there after days 15 and 30 and analyzed for antioxidant status, metabolic profile, milk yield and quality.Result: Oral supplementation of probiotic and amla powder for 30 days improved the antioxidant status, metabolic profile and milk production of summer stressed buffaloes residing in heavy metal exposed area. The percentage monetary gains from buffaloes fed probiotic and amla powder was 13.68% more as compared to control.

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