scholarly journals Reviewing Evidence for the Relationship of EEG Abnormalities and RTT Phenotype Paralleled by Insights from Animal Studies

2021 ◽  
Vol 22 (10) ◽  
pp. 5308
Author(s):  
Kirill Smirnov ◽  
Tatiana Stroganova ◽  
Sophie Molholm ◽  
Olga Sysoeva
Keyword(s):  
Animal Studies ◽  
Large Scale ◽  
Neurodevelopmental Disorder ◽  
Systematic Investigation ◽  
Mu Rhythm ◽  
Cognitive Domains ◽  
Eeg Abnormalities ◽  
Relationship Of ◽  
The Relationship ◽  
Electroencephalogram Eeg

Rett syndrome (RTT) is a rare neurodevelopmental disorder that is usually caused by mutations of the MECP2 gene. Patients with RTT suffer from severe deficits in motor, perceptual and cognitive domains. Electroencephalogram (EEG) has provided useful information to clinicians and scientists, from the very first descriptions of RTT, and yet no reliable neurophysiological biomarkers related to the pathophysiology of the disorder or symptom severity have been identified to date. To identify consistently observed and potentially informative EEG characteristics of RTT pathophysiology, and ascertain areas most worthy of further systematic investigation, here we review the literature for EEG abnormalities reported in patients with RTT and in its disease models. While pointing to some promising potential EEG biomarkers of RTT, our review identify areas of need to realize the potential of EEG including (1) quantitative investigation of promising clinical-EEG observations in RTT, e.g., shift of mu rhythm frequency and EEG during sleep; (2) closer alignment of approaches between patients with RTT and its animal models to strengthen the translational significance of the work (e.g., EEG measurements and behavioral states); (3) establishment of large-scale consortium research, to provide adequate Ns to investigate age and genotype effects.

scholarly journals Development and Application of the Owner-Bird Relationship Scale (OBRS) to Assess the Relation of Humans to Their Pet Birds

2020 ◽  
Vol 7 ◽  
Author(s):  
Anne-Kathrin Burmeister ◽  
Katrin Drasch ◽  
Monika Rinder ◽  
Sebastian Prechsl ◽  
Andrea Peschel ◽  
...  
Keyword(s):  
Quantitative Research ◽  
Animal Studies ◽  
Online Survey ◽  
Major Influence ◽  
Four Dimensions ◽  
Sociological Approach ◽  
Pet Birds ◽  
Human Animal ◽  
Relationship Of ◽  
The Relationship

Only a few birds besides domestic pigeons and poultry can be described as domesticated. Therefore, keeping a pet bird can be challenging, and the human-avian relationship will have a major influence on the quality of this cohabitation. Studies that focus on characterizing the owner-bird relationship generally use adapted cat/dog scales which may not identify its specific features. Following a sociological approach, a concept of human-animal relationship was developed leading to three types of human-animal relationship (impersonal, personal, and close personal). This concept was used to develop a 21-item owner-bird-relationship scale (OBRS). This scale was applied to measure the relationship between pet bird owners (or keepers) (n = 1,444) and their birds in an online survey performed in Germany. Factor analysis revealed that the relationship between owner and bird consisted of four dimensions: the tendency of the owner to anthropomorphize the bird; the social support the bird provides for the owner; the empathy, attentiveness, and respect of the owner toward the bird; and the relationship of the bird toward the owner. More than one quarter of the German bird owners of this sample showed an impersonal, half a personal, and less than a quarter a close personal relationship to their bird. The relationship varied with the socio-demographic characteristics of the owners, such as gender, marital status, and education. This scale supports more comprehensive quantitative research into the human-bird relationship in the broad field of human-animal studies including the psychology and sociology of animals as well as animal welfare and veterinary medicine.

Respiratory Periodicity and Electroencephalogram Arousals During Sleep in Older Adults

2007 ◽  
Vol 8 (4) ◽  
pp. 249-260 ◽  
Author(s):  
Barbara Waag Carlson ◽  
Virginia J. Neelon ◽  
John R. Carlson ◽  
Marilyn Hartman ◽  
Sunil Dogra
Keyword(s):  
Older Adults ◽  
Exploratory Study ◽  
High Variability ◽  
Arterial Oxygenation ◽  
Type B ◽  
Breathing Patterns ◽  
The Mean ◽  
Relationship Of ◽  
The Relationship ◽  
Electroencephalogram Eeg

The aim of this exploratory study was to examine the relationship of electroencephalogram (EEG) arousals to breathing patterns and the relationship of both arousals and breathing patterns to arterial oxygenation during sleep in older adults. Five older adults were monitored using standard polysomnography. Records were divided into 5-min segments and breathing patterns identified based on the level of respiratory periodicity and the variability in the frequency of breathing cycles. Standard criteria were used to determine sleep states and occurrence of EEG arousals. High respiratory periodicity was seen in 23% of the segments, whereas 24% had low respiratory periodicity with minimal variability in the frequency of breathing (Type A low respiratory periodicity) and 53% had low respiratory periodicity with high variability in the frequency of breathing (Type B low respiratory periodicity). Nearly all (97%) segments with high respiratory periodicity had EEG arousals, whereas fewer segments (33%) with low respiratory periodicity had arousals, regardless of the stage of sleep. Desaturations occurred more often in segments with high respiratory periodicity, F (2,4) = 57.3, p < .001, but overall, the mean SaO2 of segments with high respiratory periodicity did not differ from levels seen in segments with low respiratory periodicity, F( 2,4) = 0.77, ns. Our findings suggest that high respiratory periodicity is a common feature of EEG arousals and, in older adults, may be important for maintaining oxygen levels during desaturations during sleep.

scholarly journals The power of materialism among young adults: exploring the effects of values on impulsiveness and responsible financial behavior

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Andrea Lučić ◽  
Marija Uzelac ◽  
Andrea Previšić
Keyword(s):  
Young Adults ◽  
Large Scale ◽  
Brand Management ◽  
Mediating Effect ◽  
Financial Behavior ◽  
Purchase Decisions ◽  
Content Type ◽  
Financial Behaviour ◽  
Relationship Of ◽  
The Relationship

Purpose The purpose of this paper is to investigate the effects of values of materialism on cognitive and affective impulsiveness and responsible financial behavior among young adults. Design/methodology/approach A large-scale study (n = 483) was conducted on a sample of young adults 18 to 25 years of age in Croatia. Findings The research found that materialism has no direct effect on responsible financial behaviour (RFB), however, cognitive impulsiveness fully mediates the relationship of all three there three elements of materialism, centrality, success and happiness and RFB. Affective impulsiveness has no effect on the relationship. Furthermore, only materialism as centrality strongly and positively influences cognitive and affective impulsiveness. Practical implications Presented conclusions could be used by policymakers as guidelines for developing educational plans and curriculum to build financial capability and consumer protection among young adults and could be helpful for brand management activities targeting young people purchase decisions. Originality/value This paper’s ultimate purpose is to uncover the mechanism and the power of materialism on impulsiveness and responsible financial behavior. The paper’s originality is established by the focus on the investigation of materialism as an antecedent factor of impulsiveness and by questioning the nature of the relationship between materialism and responsible financial behavior through the mediating effect of impulsiveness.

scholarly journals Governance and Financial Difficulties of Conventional Banks

2019 ◽  
Vol 2 (2) ◽  
pp. 121-134
Author(s):  
La Ode Sumail
Keyword(s):  
Fixed Effects ◽  
Large Scale ◽  
Lagrange Multiplier Test ◽  
Fixed Effects Model ◽  
Insider Ownership ◽  
Financial Difficulties ◽  
Private Banks ◽  
Conventional Banks ◽  
Relationship Of ◽  
The Relationship

This study examines the connection between governance, financial performance, and financial difficulties of 27 conventional private banks during the pe3riod of 2015-2018. In order to meet the accuracy of the model in the regression analysis, the Lagrange Multiplier test was previously performed so that the Fixed Effects model was chosen. The relationship of insider ownership with ROA tends to be in the shape of inversed-U and the relationship between institutional ownership and ROA is significantly positive. The relationship between ROA and financial difficulties is significantly negative. Older or established large scale banks tend to have high ROA. This happens because the greater the assets, the healthier the cash flow of the bank, so that the potential for return of asset is quite high and financial difficulties tend to be low or avoidable.

CREATING KIN: NEW FAMILY ASSOCIATIONS AS WELFARE PROVIDERS IN LIBERALIZING JORDAN

2006 ◽  
Vol 38 (3) ◽  
pp. 349-368 ◽  
Author(s):  
Anne Marie Baylouny
Keyword(s):  
Large Scale ◽  
Family Relations ◽  
The State ◽  
National Politics ◽  
New Family ◽  
Traditional Elite ◽  
Family Associations ◽  
Relationship Of ◽  
Social Provisioning ◽  
The Relationship

In the decade and a half since economic liberalization began in Jordan, a little noticed but large-scale organizing trend has taken over the formal provision of social welfare, redefining the institutional conception of familial identity in the process. For over one third of the population, kin solidarities have been reorganized, formalized, and registered as nongovernmental organizations in an attempt to cope with the removal of basic social provisioning by the state. Although kinship clearly has been a major element in Jordan's history, the present phenomena alter traditional familial institutions, change kin lineages, and institutionalize the economic salience of family relations. In turn, the relationship of the populace to the state has changed, marginalizing previously regime-supporting groups and facilitating the implementation of economic neoliberalism without significant protest. Repackaged as charitable elements of civil society, these family associations are sanctioned and encouraged by the state and international community. Although they are not regime creations, family associations reinforce the Jordanian regime's efforts at political deliberalization. The new elites who head the organizations have been placated through indirect incorporation into the regime; they now wield significant economic power over fellow kin and have enhanced social status backed by the new group. Furthermore, the trend mainly consists of families without immediate ambitions of entering national politics. These are not the traditional elite families.

Normative Sexual Behavior in Children

PEDIATRICS ◽  
1991 ◽  
Vol 88 (3) ◽  
pp. 456-464 ◽  
Author(s):  
William N. Friedrich ◽  
Patricia Grambsch ◽  
Daniel Broughton ◽  
James Kuiper ◽  
Robert L. Beilke
Keyword(s):  
Sexual Behavior ◽  
Sexual Behaviors ◽  
Large Scale ◽  
Older Children ◽  
Community Based ◽  
History Of ◽  
Family Variables ◽  
Relationship Of ◽  
The Relationship ◽  
Internalizing And Externalizing

A large-scale, community-based survey was done to assess the frequency of a wide variety of sexual behaviors in normal preadolescent children and to measure the relationship of these behaviors to age, gender, and socioeconomic and family variables. A sample of 880 2-through 12-year-old children screened to exclude those with a history of sexual abuse were rated by their mothers using several questionnaire measures. The frequency of different behaviors varied widely, with more aggressive sexual behaviors and behaviors imitative of adults being rare. Older children (both boys and girls) were less sexual than younger children. Sexuality was found to be related to the level of general behavior problems, as measured by the Achenbach Internalizing and Externalizing T scores and to a measure of family nudity. It was not related to socioeconomic variables.

Gold–copper–bismuth mineralization in hedenbergitic skarn, Tombstone Mountains, Yukon

1987 ◽  
Vol 24 (12) ◽  
pp. 2362-2372 ◽  
Author(s):  
Isobel J. Brown ◽  
Bruce E. Nesbitt
Keyword(s):  
Large Scale ◽  
Small Volume ◽  
Gold Mineralization ◽  
Rock Interaction ◽  
The North ◽  
Mineral Assemblages ◽  
Intrusive Rocks ◽  
Porosity And Permeability ◽  
Relationship Of ◽  
The Relationship

Gold mineralization on the Marn property, Yukon, occurs in two pyroxene skarn bodies, which are adjacent to the Mount Brenner Stock in the Ogilvie Mountains. The skarns are separated by a 600 m wide monzonite intrusion and show contrasting mineralogical and geochemical characteristics in addition to quite different metal values. Significant but uneconomic Au, Ag, W, and Cu mineralization is found in skarn on the north side of the intrusion, while very low Au grades (0.052 g/t) occur at the southern contact. The mineral assemblages of both skarns are dominated by iron-rich pyroxenes. The iron content of the pyroxenes varies between Hd40 and Hd80 in the northern location and Hd80 and Hd100 in the southern skarn. A well-developed sequence of retrograde alteration affected only the northern skarn. This was probably the result of porosity and permeability differences in the early, high-temperature pyroxene skarn, which permitted greater fluid–rock interaction in the northern skarn during cooling. A small volume of diopsidic, aluminous, wollastonite-bearing skarn occurs in both the northern and southern localities. The relationship of this type of skarn to the hedenbergitic skarn is ambiguous, since there is no large-scale mineralogical zoning. The Marn is similar to hedenbergitic, auriferous skarns of Japan, where the oxidation state of the intrusive rocks is believed to be the controlling factor in the development of skarn mineralogy.

The Cultural Affiliations and Chronological Position of the Clear Fork Focus

1947 ◽  
Vol 13 (2) ◽  
pp. 97-109 ◽  
Author(s):  
J. Charles Kelley
Keyword(s):  
Large Scale ◽  
Temporal Distribution ◽  
University Of Texas ◽  
Projectile Points ◽  
Additional Information ◽  
Central Texas ◽  
The University ◽  
Relationship Of ◽  
Archaeological Cultures ◽  
The Relationship

The importance of the Clear Fork Focus as a pre-pottery archaeological complex of north-central Texas has become generally known to archaeologists through the industry of its discoverer and principal proponent, Dr. Cyrus N. Ray, of Abilene, Texas. Unfortunately, the relationship of this complex to other and comparable archaeological cultures of Texas has been largely neglected and some regrettable misinformation in regard to its chronological position has been widely disseminated. In this paper the cultural affiliations and age of the Clear Fork Focus will be discussed in terms of the evidence presented by its discoverers and from the standpoint of new data derived from large scale excavations completed by the University of Texas in the terraces of the Colorado River near Austin, Texas. Additional information obtained by the writer through study of some twelve thousand projectile points from central, south, and western Texas, and their geographic and temporal distribution also is used.

Metopes and architecture: the Hephaisteion and the Parthenon

1998 ◽  
Vol 93 ◽  
pp. 401-425 ◽  
Author(s):  
Marina Yeroulanou
Keyword(s):  
Large Scale ◽  
Relationship Of ◽  
The Relationship ◽  
Working Out

The relationship of the metopes to the architecture of the peristasis of the Hephaisteion and the Parthenon is examined in order to ascertain the extent of planning which took place before the erection of a Classical Greek temple. All relevant published measurements are taken into consideration and critically compared. On the basis of the discrepancies of the corresponding architectural and sculptural members, it is argued that the working-out of the details of the plan was not the result of large-scale drawings, but was affected after the commencement of construction. While the Hephaisteion is built largely in accordance with the conventions of a Classical Doric temple, the Parthenon, due to its unique plan, provides indications of experimentation inferred from the extensive inconsistencies at its eastern end.

scholarly journals The relationship of physical fitness and motor competence with behavioral and neuroelectric indices of attention in preschool children

2021 ◽  
Author(s):  
SHIH-CHUN KAO ◽  
Yu-Jung Tsaii ◽  
Sara Schmitt ◽  
Tsung-Min Hung
Keyword(s):  
Preschool Children ◽  
Physical Fitness ◽  
Response Selection ◽  
Muscular Endurance ◽  
Motor Competence ◽  
Controlled Attention ◽  
Competence Test ◽  
Relationship Of ◽  
The Relationship ◽  
Electroencephalogram Eeg

The present study examined the associations of physical fitness and motorcompetence with P3 and alpha desynchronization (ERD), two neuroelectric indices ofbrain development underlying controlled attention, in 4-6 year-old preschool children. Allparticipants completed physical fitness and motor competence test batteries and anauditory oddball task while electroencephalogram (EEG) was recorded. Resultsrevealed that increased muscular power, muscular endurance, physical fitness, andmotor competence were associated better attentional task performance. Analysis onneuroelectric indices showed that muscular endurance was related to increased P3amplitude, while the increases in physical fitness and motor competence wereassociated with greater upper alpha (10-12 Hz) ERD following the stimulus evaluationand response selection. Further, the negative associations of physical fitness and motorcompetence with task response time were mediated by the upper alpha ERD. Thesefindings highlight the importance of early childhood motor competence and physicalfitness, especially muscular endurance, to neurocognitive function.

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