scholarly journals Convolutional Neural Network Classifies Pathological Voice Change in Laryngeal Cancer with High Accuracy

2020 ◽  
Vol 9 (11) ◽  
pp. 3415
Author(s):  
HyunBum Kim ◽  
Juhyeong Jeon ◽  
Yeon Jae Han ◽  
YoungHoon Joo ◽  
Jonghwan Lee ◽  
...  

Voice changes may be the earliest signs in laryngeal cancer. We investigated whether automated voice signal analysis can be used to distinguish patients with laryngeal cancer from healthy subjects. We extracted features using the software package for speech analysis in phonetics (PRAAT) and calculated the Mel-frequency cepstral coefficients (MFCCs) from voice samples of a vowel sound of /a:/. The proposed method was tested with six algorithms: support vector machine (SVM), extreme gradient boosting (XGBoost), light gradient boosted machine (LGBM), artificial neural network (ANN), one-dimensional convolutional neural network (1D-CNN) and two-dimensional convolutional neural network (2D-CNN). Their performances were evaluated in terms of accuracy, sensitivity, and specificity. The result was compared with human performance. A total of four volunteers, two of whom were trained laryngologists, rated the same files. The 1D-CNN showed the highest accuracy of 85% and sensitivity and sensitivity and specificity levels of 78% and 93%. The two laryngologists achieved accuracy of 69.9% but sensitivity levels of 44%. Automated analysis of voice signals could differentiate subjects with laryngeal cancer from those of healthy subjects with higher diagnostic properties than those performed by the four volunteers.

Risks ◽  
2021 ◽  
Vol 9 (11) ◽  
pp. 202
Author(s):  
Ge Gao ◽  
Hongxin Wang ◽  
Pengbin Gao

In China, SMEs are facing financing difficulties, and commercial banks and financial institutions are the main financing channels for SMEs. Thus, a reasonable and efficient credit risk assessment system is important for credit markets. Based on traditional statistical methods and AI technology, a soft voting fusion model, which incorporates logistic regression, support vector machine (SVM), random forest (RF), eXtreme Gradient Boosting (XGBoost), and Light Gradient Boosting Machine (LightGBM), is constructed to improve the predictive accuracy of SMEs’ credit risk. To verify the feasibility and effectiveness of the proposed model, we use data from 123 SMEs nationwide that worked with a Chinese bank from 2016 to 2020, including financial information and default records. The results show that the accuracy of the soft voting fusion model is higher than that of a single machine learning (ML) algorithm, which provides a theoretical basis for the government to control credit risk in the future and offers important references for banks to make credit decisions.


Author(s):  
Oguz Akbilgic ◽  
Liam Butler ◽  
Ibrahim Karabayir ◽  
Patricia P Chang ◽  
Dalane W Kitzman ◽  
...  

Abstract Aims Heart failure (HF) is a leading cause of death. Early intervention is the key to reduce HF-related morbidity and mortality. This study assesses the utility of electrocardiograms (ECGs) in HF risk prediction. Methods and results Data from the baseline visits (1987–89) of the Atherosclerosis Risk in Communities (ARIC) study was used. Incident hospitalized HF events were ascertained by ICD codes. Participants with good quality baseline ECGs were included. Participants with prevalent HF were excluded. ECG-artificial intelligence (AI) model to predict HF was created as a deep residual convolutional neural network (CNN) utilizing standard 12-lead ECG. The area under the receiver operating characteristic curve (AUC) was used to evaluate prediction models including (CNN), light gradient boosting machines (LGBM), and Cox proportional hazards regression. A total of 14 613 (45% male, 73% of white, mean age ± standard deviation of 54 ± 5) participants were eligible. A total of 803 (5.5%) participants developed HF within 10 years from baseline. Convolutional neural network utilizing solely ECG achieved an AUC of 0.756 (0.717–0.795) on the hold-out test data. ARIC and Framingham Heart Study (FHS) HF risk calculators yielded AUC of 0.802 (0.750–0.850) and 0.780 (0.740–0.830). The highest AUC of 0.818 (0.778–0.859) was obtained when ECG-AI model output, age, gender, race, body mass index, smoking status, prevalent coronary heart disease, diabetes mellitus, systolic blood pressure, and heart rate were used as predictors of HF within LGBM. The ECG-AI model output was the most important predictor of HF. Conclusions ECG-AI model based solely on information extracted from ECG independently predicts HF with accuracy comparable to existing FHS and ARIC risk calculators.


2021 ◽  
Author(s):  
Seong Hwan Kim ◽  
Eun-Tae Jeon ◽  
Sungwook Yu ◽  
Kyungmi O ◽  
Chi Kyung Kim ◽  
...  

Abstract We aimed to develop a novel prediction model for early neurological deterioration (END) based on an interpretable machine learning (ML) algorithm for atrial fibrillation (AF)-related stroke and to evaluate the prediction accuracy and feature importance of ML models. Data from multi-center prospective stroke registries in South Korea were collected. After stepwise data preprocessing, we utilized logistic regression, support vector machine, extreme gradient boosting, light gradient boosting machine (LightGBM), and multilayer perceptron models. We used the Shapley additive explanations (SHAP) method to evaluate feature importance. Of the 3,623 stroke patients, the 2,363 who had arrived at the hospital within 24 hours of symptom onset and had available information regarding END were included. Of these, 318 (13.5%) had END. The LightGBM model showed the highest area under the receiver operating characteristic curve (0.778, 95% CI, 0.726 - 0.830). The feature importance analysis revealed that fasting glucose level and the National Institute of Health Stroke Scale score were the most influential factors. Among ML algorithms, the LightGBM model was particularly useful for predicting END, as it revealed new and diverse predictors. Additionally, the SHAP method can be adjusted to individualize the features’ effects on the predictive power of the model.


2017 ◽  
Vol 25 (3) ◽  
pp. 321-330 ◽  
Author(s):  
Shang Gao ◽  
Michael T Young ◽  
John X Qiu ◽  
Hong-Jun Yoon ◽  
James B Christian ◽  
...  

Abstract Objective We explored how a deep learning (DL) approach based on hierarchical attention networks (HANs) can improve model performance for multiple information extraction tasks from unstructured cancer pathology reports compared to conventional methods that do not sufficiently capture syntactic and semantic contexts from free-text documents. Materials and Methods Data for our analyses were obtained from 942 deidentified pathology reports collected by the National Cancer Institute Surveillance, Epidemiology, and End Results program. The HAN was implemented for 2 information extraction tasks: (1) primary site, matched to 12 International Classification of Diseases for Oncology topography codes (7 breast, 5 lung primary sites), and (2) histological grade classification, matched to G1–G4. Model performance metrics were compared to conventional machine learning (ML) approaches including naive Bayes, logistic regression, support vector machine, random forest, and extreme gradient boosting, and other DL models, including a recurrent neural network (RNN), a recurrent neural network with attention (RNN w/A), and a convolutional neural network. Results Our results demonstrate that for both information tasks, HAN performed significantly better compared to the conventional ML and DL techniques. In particular, across the 2 tasks, the mean micro and macroF-scores for the HAN with pretraining were (0.852,0.708), compared to naive Bayes (0.518, 0.213), logistic regression (0.682, 0.453), support vector machine (0.634, 0.434), random forest (0.698, 0.508), extreme gradient boosting (0.696, 0.522), RNN (0.505, 0.301), RNN w/A (0.637, 0.471), and convolutional neural network (0.714, 0.460). Conclusions HAN-based DL models show promise in information abstraction tasks within unstructured clinical pathology reports.


2021 ◽  
pp. 22-37
Author(s):  
Han Gao ◽  
Pei Shan Fam ◽  
Lea Tien Tay ◽  
Heng Chin Low

Tree-based gradient boosting (TGB) models gain popularity in various areas due to their powerful prediction ability and fast processing speed. This study aims to compare the landslide spatial prediction performance of TGB models and non-tree-based machine learning (NML) models in Penang Island, Malaysia. Two specific instances of TGB models, eXtreme Gradient Boosting (XGBoost) and Light Gradient Boosting Machine (LightGBM) and two specific instances of NML models, artificial neural network (ANN) and support vector machine (SVM), are applied to make predictions of landslide susceptibility. Feature selection and oversampling techniques are considered to improve the prediction performance as well. The results are analyzed and discussed mainly based on receiver operating characteristic (ROC) curves as well as the area under the curves (AUC). The results show that TGB models give better prediction performance compared to NML models, no matter what the sample size is. The TGB models’ performances are improved when training with the dataset considering either feature selection or oversampling techniques. The highest AUC value of 0.9525 is obtained from the combination of XGBoost and SMOTE. The landslide susceptibility maps (LSMs) produced by XGBoost and LightGBM can provide valuable information in landslide management and mitigation in Penang Island, Malaysia.


IEEE Access ◽  
2020 ◽  
Vol 8 ◽  
pp. 17804-17818 ◽  
Author(s):  
Halefom Tekle Weldegebriel ◽  
Han Liu ◽  
Anwar Ul Haq ◽  
Emmanuel Bugingo ◽  
Defu Zhang

Sensors ◽  
2021 ◽  
Vol 21 (20) ◽  
pp. 6714
Author(s):  
Artur Klepaczko ◽  
Eli Eikefjord ◽  
Arvid Lundervold

Quantification of renal perfusion based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) requires determination of signal intensity time courses in the region of renal parenchyma. Thus, selection of voxels representing the kidney must be accomplished with special care and constitutes one of the major technical limitations which hampers wider usage of this technique as a standard clinical routine. Manual segmentation of renal compartments—even if performed by experts—is a common source of decreased repeatability and reproducibility. In this paper, we present a processing framework for the automatic kidney segmentation in DCE-MR images. The framework consists of two stages. Firstly, kidney masks are generated using a convolutional neural network. Then, mask voxels are classified to one of three regions—cortex, medulla, and pelvis–based on DCE-MRI signal intensity time courses. The proposed approach was evaluated on a cohort of 10 healthy volunteers who underwent the DCE-MRI examination. MRI scanning was repeated on two time events within a 10-day interval. For semantic segmentation task we employed a classic U-Net architecture, whereas experiments on voxel classification were performed using three alternative algorithms—support vector machines, logistic regression and extreme gradient boosting trees, among which SVM produced the most accurate results. Both segmentation and classification steps were accomplished by a series of models, each trained separately for a given subject using the data from other participants only. The mean achieved accuracy of the whole kidney segmentation was 94% in terms of IoU coefficient. Cortex, medulla and pelvis were segmented with IoU ranging from 90 to 93% depending on the tissue and body side. The results were also validated by comparing image-derived perfusion parameters with ground truth measurements of glomerular filtration rate (GFR). The repeatability of GFR calculation, as assessed by the coefficient of variation was determined at the level of 14.5 and 17.5% for the left and right kidney, respectively and it improved relative to manual segmentation. Reproduciblity, in turn, was evaluated by measuring agreement between image-derived and iohexol-based GFR values. The estimated absolute mean differences were equal to 9.4 and 12.9 mL/min/1.73 m2 for scanning sessions 1 and 2 and the proposed automated segmentation method. The result for session 2 was comparable with manual segmentation, whereas for session 1 reproducibility in the automatic pipeline was weaker.


Author(s):  
Naipeng Liu ◽  
Hui Gao ◽  
Zhen Zhao ◽  
Yule Hu ◽  
Longchen Duan

AbstractIn gas drilling operations, the rate of penetration (ROP) parameter has an important influence on drilling costs. Prediction of ROP can optimize the drilling operational parameters and reduce its overall cost. To predict ROP with satisfactory precision, a stacked generalization ensemble model is developed in this paper. Drilling data were collected from a shale gas survey well in Xinjiang, northwestern China. First, Pearson correlation analysis is used for feature selection. Then, a Savitzky-Golay smoothing filter is used to reduce noise in the dataset. In the next stage, we propose a stacked generalization ensemble model that combines six machine learning models: support vector regression (SVR), extremely randomized trees (ET), random forest (RF), gradient boosting machine (GB), light gradient boosting machine (LightGBM) and extreme gradient boosting (XGB). The stacked model generates meta-data from the five models (SVR, ET, RF, GB, LightGBM) to compute ROP predictions using an XGB model. Then, the leave-one-out method is used to verify modeling performance. The performance of the stacked model is better than each single model, with R2 = 0.9568 and root mean square error = 0.4853 m/h achieved on the testing dataset. Hence, the proposed approach will be useful in optimizing gas drilling. Finally, the particle swarm optimization (PSO) algorithm is used to optimize the relevant ROP parameters.


Author(s):  
Robin Ghosh ◽  
Anirudh Reddy Cingreddy ◽  
Venkata Melapu ◽  
Sravanthi Joginipelli ◽  
Supratik Kar

Alzheimer's disease (AD) is one of the most common forms of dementia and the sixth-leading cause of death in older adults. The presented study has illustrated the applications of deep learning (DL) and associated methods, which could have a broader impact on identifying dementia stages and may guide therapy in the future for multiclass image detection. The studied datasets contain around 6,400 magnetic resonance imaging (MRI) images, each segregated into the severity of Alzheimer's classes: mild dementia, very mild dementia, non-dementia, moderate dementia. These four image specifications were used to classify the dementia stages in each patient applying the convolutional neural network (CNN) algorithm. Employing the CNN-based in silico model, the authors successfully classified and predicted the different AD stages and got around 97.19% accuracy. Again, machine learning (ML) techniques like extreme gradient boosting (XGB), support vector machine (SVM), k-nearest neighbor (KNN), and artificial neural network (ANN) offered accuracy of 96.62%, 96.56%, 94.62, and 89.88%, respectively.


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