scholarly journals COVID-19 Pandemic in Rio de Janeiro, Brazil: A Social Inequality Report

Medicina ◽  
2021 ◽  
Vol 57 (6) ◽  
pp. 596
Author(s):  
Yago Bernardo ◽  
Denes do Rosario ◽  
Carlos Conte-Junior
Keyword(s):  
Observational Study ◽  
Social Inequality ◽  
Rio De Janeiro ◽  
Case Fatality Rate ◽  
Case Fatality ◽  
Mitigation Measures ◽  
Fatality Rate ◽  
Retrospective Report ◽  
The Social ◽  
The City

Background and Objectives: To perform a retrospective report on the lethality of COVID-19 in different realities in the city of Rio de Janeiro (RJ). Materials and Methods: We accomplished an observational study by collecting the data about total confirmed cases and deaths due to COVID-19 in the top 10 high social developed neighborhoods and top 10 most populous favelas in RJ to determine the case-fatality rate (CFR) and compare these two different realities. Results: CFR was significatively higher in poverty areas of RJ, reaching a mean of 9.08% in the most populous favelas and a mean of 4.87% in the socially developed neighborhoods. Conclusions: The social mitigation measures adopted in RJ have benefited only smaller portions of the population, excluding needy communities.

scholarly journals The Uncertainties Underlying Herd Immunity against COVID-19

2020 ◽  
Author(s):  
Farid Rahimi ◽  
Amin Talebi Bezmin Abadi
Keyword(s):  
Antiviral Therapy ◽  
Case Fatality Rate ◽  
Herd Immunity ◽  
Case Fatality ◽  
Healthcare Systems ◽  
Fatality Rate ◽  
Economic Implications ◽  
Rate Transmission ◽  
The Social ◽  
And Control

Herd immunity happens when a relatively large proportion of a population becomes infected by an agent, subsequently recovers, and attains immunity against the same agent. That proportion thus indirectly protects the naïve population by preventing the spread of the infection. Herd immunity has been suggested to interrupt and control the COVID-19 pandemic. However, relying on establishing herd immunity can be catastrophic considering the virulence and lethality of SARS-CoV-2. Meanwhile our understanding of the pathogenesis, case-fatality rate, transmission routes, and antiviral therapy for COVID-19 remains limited now. Interrupting or slowing the COVID-19 transmission seems more opportune than vaccination, antiviral therapy, or herd immunity, all of which will take some time to yield. Thus, social distancing, face-masking, and hygiene are the most appropriate immediate countermeasures. Because the social fabrics, economic implications, and local demands of various nations are unique, early relaxation of restrictions may seem hasty particularly when fatality rates are high, or when the healthcare systems could be inadequate or become inundated. Conclusively, avoiding any overwhelmingly risky approach in fighting the pandemic is prudent.

scholarly journals Policy Disparities in Fighting COVID-19 Among Japan, Italy, Singapore and China

2020 ◽  
Author(s):  
Xiaohan Wang ◽  
Leiyu Shi ◽  
Yuyao Zhang ◽  
Haiqian Chen ◽  
Gang Sun
Keyword(s):  
Prevention And Control ◽  
Case Fatality Rate ◽  
Case Fatality ◽  
Mitigation Measures ◽  
Cumulative Number ◽  
Fatality Rate ◽  
Epidemic Control ◽  
Growth Trend ◽  
Control Policies ◽  
And Control

Abstract Objective This study systematically summarizes the COVID-19 prevention and control policies of Japan, Italy, China and Singapore in order to provide policy basis for other countries currently coping with the COVID-19 pandemic.Methods This study summarizes the epidemic prevention and control policies in Japan, Italy, China, and Singapore, and analyzes the effects of policies in the four countries using official statistics.Results As of May 27, 2020, the growth trend of new cases in Japan, Italy, China and Singapore has all stabilized. However, the cumulative number of confirmed cases (231139) and case-fatality rate (14.3%) in Italy far exceeded those in the other three countries, and the effect of epidemic control was inferior. Singapore began to experience a domestic resurgence after April 5, with a cumulative number of confirmed cases reaching 32876, but the case-fatality rate remained extremely low (0.1%). The growth of cumulative confirmed cases in China (84547) is almost stagnant, and the case-fatality rate is low (5.5%). The growth of cumulative confirmed cases in Japan (16661) increased slowly, and the case-fatality rate (4.8%) was slightly lower than that in China.Conclusion This study divides the epidemic prevention and control policies of the four countries into two categories: the blocking measures taken by China and Singapore, and the mitigation measures taken by Japan and Italy. According to the results of epidemic control in the four countries, we can conclude that the blocking measures are more effective. Pay attention to the admission of mild patients and cases tracking as the core strategy of blocking measures, which can be considered in countries all over the world.

scholarly journals CLINICAL PROFILE OF PLASMODIUM VIVAX MALARIA IN CHILDREN

2021 ◽  
Vol 5 (8) ◽  
Author(s):  
Kalpesh Kumar Jain ◽  
Jasraj Bohra
Keyword(s):  
Observational Study ◽  
Plasmodium Vivax ◽  
Vivax Malaria ◽  
Case Fatality Rate ◽  
Case Fatality ◽  
Fatality Rate ◽  
Common Presentation ◽  
Clinical Presentations ◽  
Plasmodium Vivax Malaria ◽  
Severity Criteria

Background: To study clinical presentations and complications of P. vivax malaria Methods: A prospective hospital-based clinical observational study was conducted on 100 patients under age of 14 years were enrolled in the study. Result: The most common presentation was fever followed by pallor. Among the total of 100 cases studied 2 cases died with a case fatality rate of 2%. Among the total of 100 cases studied 5 cases (10%) required ICU admission. Conclusion: P. vivax monoinfection tends to have severe complications in children. There is a need to review severity criteria for P. vivax malaria. Keywords: Vivax, Fever, ICU

scholarly journals Policy disparities in fighting COVID-19 among Japan, Italy, Singapore and China

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Xiaohan Wang ◽  
Leiyu Shi ◽  
Yuyao Zhang ◽  
Haiqian Chen ◽  
Gang Sun
Keyword(s):  
Prevention And Control ◽  
Case Fatality Rate ◽  
Case Fatality ◽  
Health Resources ◽  
Mitigation Measures ◽  
Cumulative Number ◽  
Fatality Rate ◽  
Epidemic Control ◽  
Control Policies ◽  
And Control

Abstract Objective In order to provide experiences for international epidemic control, this study systematically summarized the Coronavirus disease 2019 (COVID-19) prevention and control policies in Japan, Italy, China and Singapore, and also analyzed the possible inequalities that exist in these response approaches to improve global infectious disease control. Methods We summarized the epidemic prevention and control policies in Japan, Italy, China, and Singapore, and analyzed the policy effects of these four countries by using the data published by Johns Hopkins Coronavirus Resource Center. Results As of May 27, 2020, the growing trend of new cases in Japan, Italy, China and Singapore has stabilized. However, the cumulative number of confirmed cases (231139) and case-fatality rate (14.3%) in Italy far exceeded those in the other three countries, and the effect of epidemic control was inferior. Singapore began to experience a domestic resurgence after April 5, with a cumulative number of confirmed cases reaching 32,876, but the case-fatality rate remained extremely low (0.1%). The growth of cumulative confirmed cases in China (84547) was almost stagnant, and the case-fatality rate was low (5.5%). The growth of cumulative confirmed cases in Japan (16661) increased slowly, and the case-fatality rate (4.8%) was slightly lower than that in China. Conclusion This study divided the epidemic prevention and control policies of the four countries into two categories: the blocking measures adopted by China and Singapore, and the mitigation measures adopted by Japan and Italy. According to the Epidemic control results of these four countries, we can conclude that the blocking measures were generally effective. As the core strategy of blocking measures, admitting mild patients into hospital and cases tracing helped curb the spread of the outbreak in Singapore and China. Countries should choose appropriate response strategies on the premise of considering their own situation, increase investment in health resources to ensure global health equity, and eventually control the spread of infectious diseases in the world effectively.

scholarly journals A Time-dependent mathematical model for COVID-19 transmission dynamics and analysis of critical and hospitalized cases with bed requirements

2020 ◽  
Author(s):  
Avaneesh Singh ◽  
Manish Kumar Bajpai ◽  
Shyam Lal Gupta
Keyword(s):  
Case Fatality Rate ◽  
Case Fatality ◽  
The United States ◽  
Time Dependent ◽  
Fatality Rate ◽  
Proposed Model ◽  
The Social ◽  
Death Cases ◽  
Daily Hospitalization ◽  
Over Time

AbstractA time-dependent SEAIHCRD model is the extension of the SEIR model, which includes some new compartment that is asymptomatic infectious people, hospitalized people, critical people, and dead compartments. In this article, we analyzed six countries, namely the United States, Brazil, India, South Africa, Russia, and Mexico. A time-dependent SEAIHCRD model calculates the magnitude of peaks for exposed people, asymptomatic infectious people, symptomatic infectious people, hospitalized people, the number of people admitted to ICUs, and the number of COVID-19 deaths over time. It also computes the spread scenario and endpoints of disease. The proposed model also involves asymptomatic infectious individuals. To estimate the various parameters, we first collect the data and fit that using the Lavenberg-Marquardt model for death cases. Then we calculate infection rate, recovery rate, case fatality rate, and the basic reproduction number over time. We calculate two types of case fatality rates: one is the daily case fatality rate, and the other is the total case fatality rate. The proposed model includes the social distance parameter, various age classes, hospital beds for severe cases, and ICU beds or ventilators for critical cases. This model will be useful to determine various essential parameters such as daily hospitalization rate, daily death rates, including the requirement of normal and ICU beds during peak days of infection.

Impact of hydroxychloroquin/azithromycin protocol on COVID-19 case-fatality rate reduction in Algeria. (Preprint)

2020 ◽  
Author(s):  
Ahmed Youssef Kada
Keyword(s):  
Case Fatality Rate ◽  
Doubling Time ◽  
Case Fatality ◽  
World Health ◽  
Fatality Rate ◽  
Therapeutic Protocol ◽  
First Case ◽  
The World ◽  
The Impact ◽  
At Home

BACKGROUND Covid-19 is an emerging infectious disease like viral zoonosis caused by new coronavirus SARS CoV 2. On December 31, 2019, Wuhan Municipal Health Commission in Hubei province (China) reported cases of pneumonia, the origin of which is a new coronavirus. Rapidly extendable around the world, the World Health Organization (WHO) declares it pandemic on March 11, 2020. This pandemic reaches Algeria on February 25, 2020, date on which the Algerian minister of health, announced the first case of Covid-19, a foreign citizen. From March 1, a cluster is formed in Blida and becomes the epicentre of the coronavirus epidemic in Algeria, its total quarantine is established on March 24, 2020, it will be smoothly alleviated on April 24. A therapeutic protocol based on hydroxychloroquine and azithromycin was put in place on March 23, for complicated cases, it was extended to all the cases confirmed on April 06. OBJECTIVE This study aimed to demonstrate the effectiveness of hydroxychloroquin/azithromycin protocol in Algeria, in particular after its extension to all patients diagnosed COVID-19 positive on RT-PCR test. We were able to illustrate this fact graphically, but not to prove it statistically because the design of our study, indeed in the 7 days which followed generalization of therapeutic protocol, case fatality rate decrease and doubling time increase, thus confirming the impact of wide and early prescription of hydroxychloroquin/azithromycin protocol. METHODS We have analyzed the data collected from press releases and follow-ups published daily by the Ministry of Health, we have studied the possible correlations of these data with certain events or decisions having a possible impact on their development, such as confinement at home and its reduction, the prescription of hydroxychloroquine/azithromycin combination for serious patients and its extension to all positive COVID subjects. Results are presented in graphics, the data collection was closed on 31/05/2020. RESULTS Covid-19 pandemic spreads from February 25, 2020, when a foreign citizen is tested positive, on March 1 a cluster is formed in the city of Blida where sixteen members of the same family are infected during a wedding party. Wilaya of Blida becomes the epicentre of coronavirus epidemic in Algeria and lockdown measures taken, while the number of national cases diagnosed begins to increases In any event, the association of early containment measures combined with a generalized initial treatment for all positive cases, whatever their degree of severity, will have contributed to a reduction in the fatality rate of COVID 19 and a slowing down of its doubling time. CONCLUSIONS In Algeria, the rapid combination of rigorous containment measure at home and early generalized treatment with hydroxychloroquin have demonstrated their effectiveness in terms of morbidity and mortality, the classic measures of social distancing and hygiene will make it possible to perpetuate these results by reducing viral transmission, the only unknown, the reopening procedure which can only be started after being surrounded by precautions aimed at ensuring the understanding of the population. CLINICALTRIAL Algeria, Covid-19, pandemic, hydroxychloroquin, azithromycin, case fatality rate

scholarly journals Author Correction: Calcium channel blocker amlodipine besylate therapy is associated with reduced case fatality rate of COVID-19 patients with hypertension

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Lei-Ke Zhang ◽  
Yuan Sun ◽  
Haolong Zeng ◽  
Qingxing Wang ◽  
Xiaming Jiang ◽  
...  
Keyword(s):  
Calcium Channel ◽  
Calcium Channel Blocker ◽  
Case Fatality Rate ◽  
Channel Blocker ◽  
Case Fatality ◽  
Fatality Rate ◽  
Amlodipine Besylate

A Correction to this paper has been published: https://doi.org/10.1038/s41421-021-00267-0

scholarly journals Early determination of case fatality rate of COVID-19 pandemic during the ongoing Yemeni armed conflict

2021 ◽  
pp. 1-15
Author(s):  
Abdulla Salem Bin Ghouth ◽  
Ali Ahmed Al-Waleedi ◽  
Marhami Fahriani ◽  
Firzan Nainu ◽  
Harapan Harapan
Keyword(s):  
Young Adults ◽  
Intensive Care ◽  
Armed Conflict ◽  
Case Fatality Rate ◽  
Preventive Measures ◽  
Case Fatality ◽  
Fatality Rate ◽  
Mechanical Ventilators ◽  
Poor Outcomes

Abstract Objectives: To determine the case-fatality rate (CFR) of coronavirus disease 2019 (COVID-19) and its associated determinants in order to understand the true magnitude of the problem during ongoing conflict in Yemen. Methods: The CFR among confirmed COVID-19 cases in Yemen was calculated. The data was retrieved from national COVID-19 surveillance between April 10, when the first COVID-19 case reported, and May 31, 2020. Results: A total of 419 confirmed COVID-19 cases were reported. There were 14.1% and 5.7% of cases who required intensive care and mechanical ventilators, respectively. Out of total cases, 95 deaths were reported, giving CFR of 22.6% which is much higher compared to other countries. CFR was significantly higher among elderly compared to young adults and varied between governorates. Mortality was associated with preexisting hypertension (OR: 2.30; 95%CI: 1.58, 3.54) and diabetes (OR: 1.68; 95%CI: 1.08, 2.61). Conclusions: Elderly and those with comorbidities, in particular hypertension and diabetes, have higher risk for poor outcomes and therefore should receive more attention in the clinical setting. Preventive measures should also be prioritized to protect those groups in order to reduce the severe cases and deaths-associated COVID-19 in armed-conflict.

scholarly journals Regional Variability in COVID-19 Case Fatality Rate in Canada, February–December 2020

2021 ◽  
Vol 18 (4) ◽  
pp. 1839
Author(s):  
Eunha Shim
Keyword(s):  
British Columbia ◽  
Case Fatality Rate ◽  
Case Reports ◽  
Case Fatality ◽  
Health Interventions ◽  
Fatality Rate ◽  
Older Individuals ◽  
Regional Variability ◽  
Provincial Level ◽  
Mortality Burden

A total of 475,214 COVID-19 cases, including 13,659 deaths, had been recorded in Canada as of 15 December 2020. The daily reports of confirmed cases and deaths in Canada prior to 15 December 2020 were obtained from publicly available sources and used to examine regional variations in case fatality rate (CFR). Based on a factor of underestimation and the duration of time from symptom onset to death, the time-delay adjusted CFR for COVID-19 was estimated in the four most affected provinces (Quebec, Ontario, Alberta, and British Columbia) and nationwide. The model-based adjusted CFR was higher than the crude CFR throughout the pandemic, primarily owing to the incorporation in our estimation of the delay between case reports and deaths. The adjusted CFR in Canada was estimated to be 3.36% nationwide. At the provincial level, the adjusted CFR was the highest in Quebec (5.13%)—where the proportion of deaths among older individuals was also the highest among the four provinces—followed by Ontario (3.17%), British Columbia (1.97%), and Alberta (1.13%). Provincial-level variations in CFR were considerable, suggesting that public health interventions focused on densely populated areas and elderly individuals can ameliorate the mortality burden of the COVID-19 pandemic.

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