scholarly journals Early determination of case fatality rate of COVID-19 pandemic during the ongoing Yemeni armed conflict

2021 ◽  
pp. 1-15
Author(s):  
Abdulla Salem Bin Ghouth ◽  
Ali Ahmed Al-Waleedi ◽  
Marhami Fahriani ◽  
Firzan Nainu ◽  
Harapan Harapan
Keyword(s):  
Young Adults ◽  
Intensive Care ◽  
Armed Conflict ◽  
Case Fatality Rate ◽  
Preventive Measures ◽  
Case Fatality ◽  
Fatality Rate ◽  
Mechanical Ventilators ◽  
Poor Outcomes

Abstract Objectives: To determine the case-fatality rate (CFR) of coronavirus disease 2019 (COVID-19) and its associated determinants in order to understand the true magnitude of the problem during ongoing conflict in Yemen. Methods: The CFR among confirmed COVID-19 cases in Yemen was calculated. The data was retrieved from national COVID-19 surveillance between April 10, when the first COVID-19 case reported, and May 31, 2020. Results: A total of 419 confirmed COVID-19 cases were reported. There were 14.1% and 5.7% of cases who required intensive care and mechanical ventilators, respectively. Out of total cases, 95 deaths were reported, giving CFR of 22.6% which is much higher compared to other countries. CFR was significantly higher among elderly compared to young adults and varied between governorates. Mortality was associated with preexisting hypertension (OR: 2.30; 95%CI: 1.58, 3.54) and diabetes (OR: 1.68; 95%CI: 1.08, 2.61). Conclusions: Elderly and those with comorbidities, in particular hypertension and diabetes, have higher risk for poor outcomes and therefore should receive more attention in the clinical setting. Preventive measures should also be prioritized to protect those groups in order to reduce the severe cases and deaths-associated COVID-19 in armed-conflict.

scholarly journals An Assessment of the Philippine Hospital Resources as Predictors of the Case Fatality Rate of COVID – 19

2022 ◽  
Vol 4 (1) ◽  
pp. 118-130
Author(s):  
Paul Benjamin Barrion ◽  
Ray Patrick Basco ◽  
Kevin jamir Pigao
Keyword(s):  
Case Fatality Rate ◽  
Case Fatality ◽  
Health Resources ◽  
Ordinary Least Squares ◽  
The Philippines ◽  
Medical Attention ◽  
Fatality Rate ◽  
Mechanical Ventilators ◽  
Department Of Health ◽  
Hospital Resources

In the heightened effects of the pandemic, health resources have been in constant limbo as supplies and availability of hospital resources take a toll as COVID-19 cases surge, resulting in shortages. Thus, health systems are overwhelmed, resulting in a higher fatality rate since the capacity to provide medical attention is diminished. In this paper, hospital resources refer to mechanical ventilators, ICU, isolation, and ward beds which are the critical factors of the case fatality rate (CFR) of COVID-19 in the Philippines. Data were retrieved from the Department of Health (DOH) Case Bulletins from October 26, 2020, to June 30, 2021, with 248 total observations. This research used the Ordinary Least Squares (OLS) Multiple Regression to determine if hospital resources are the predictors of the case fatality rate of COVID-19. Furthermore, the results show a significant relationship between the hospital resources and the case fatality rate of COVID-19 in the Philippines. This study can become a framework for further research concerned about hospital resources as the predictors of case fatality rates of different diseases in a pandemic.  

scholarly journals An Epidemiological Analysis of COVID-19 cases from Jan to July 2020 in Kelantan, Malaysia

2021 ◽  
pp. 149-165
Author(s):  
Hazlienor Mohd Hatta ◽  
Nik Mohd Hafiz Mohd Fuzi ◽  
Nur Dalilah Mohd Zin ◽  
Afiq Izzudin A Rahim ◽  
Najihah Mahfuzah Zakria ◽  
...  
Keyword(s):  
Case Fatality Rate ◽  
Case Fatality ◽  
Older Age ◽  
Diabetic Patients ◽  
Fatality Rate ◽  
Mechanical Ventilators ◽  
Icu Admission ◽  
Local Setting ◽  
Adjusted Incidence Rate ◽  
Choropleth Map

As the global battle against COVID-19 rages on, Malaysia’s concerted effort in stemming the spread is commendable. This study characterized the epidemiology of COVID-19 aiming towards understanding the disease in a local setting for better preparation and management. A nation-based e-COVID reporting system was used to collect data on laboratory-confirmed COVID-19 cases in Kelantan from January to July 2020. Information from investigation reports was also reviewed. Analyses comprised of the estimation of incidence and case-fatality rate, summary of demographic and clinical characteristics including the age and sex distributions, construction of the epidemiological curve and choropleth map, and appraisal of healthcare usage. Multiple logistic regression was used to determine the risk factors for Intensive Care Unit (ICU) admission. A total of 166 cases reported in Kelantan until July 2020. Cases peaked during March before steadily declining and were concentrated in the capital. The age-adjusted incidence rate was 9.4/100,000 populations with a case-fatality rate of 2.4%. The median age was 37 years and 78% were male. The predominant symptoms were fever and cough while 25% of cases were asymptomatic. About 57% of cases were identified by active case detection and 97% had exposure risk. Potentially infected cases were isolated within a median of 7 days after exposure, even before the diagnosis. All cases were hospitalized with a median of 14 bed days, while 12% admitted to ICU, and 3% required mechanical ventilators. Significant factors for ICU admission were older age (AOR: 1.05, 95% CI: 1.02, 1.09, P = 0.001) and diabetes mellitus (AOR 4.55, 95% CI: 1.36, 15.25, P = 0.014). Although all ages appeared susceptible to COVID-19, older age and diabetic patients were more vulnerable. Kelantan’s targeted approaches of prompt identification and isolation of potentially infected individuals have been effective in limiting the transmission, allowing sufficient healthcare capacity in managing the pandemic.

COVID-19 (NOVEL CORONA VIRUS-2019)- TRENDS OF CORONA PANDEMIC OVER A PERIOD OF ONE YEAR IN HIMALAYAN REGION IN INDIA.

2021 ◽  
pp. 12-14
Author(s):  
Kamlesh Sharma ◽  
Ram Lal Sharma
Keyword(s):  
Public Health ◽  
Recovery Rate ◽  
Case Fatality Rate ◽  
Preventive Measures ◽  
Case Fatality ◽  
Himalayan Region ◽  
Fatality Rate ◽  
Public Health Threat ◽  
One Year ◽  
Authentic Data

COVID-19 is a emerging disease and is of public health importance.This study was done to analyse the trends of corona pandemic over a period of one year in Himalayan region in India. Data regarding state statistics from January 2020 to January 2021,was gathered from various sources. Since objective and authentic data was released by different agencies daily and reported to WHO, so the state prole of new cases, cumulative cases, recoveries, cumulative deaths, samples tested, positive samples was taken based on availability of information from National Health Mission site, other state websites and news papers and analysed for various parameters. The current study conducted in Himachal Pradesh showed Case fatality rate as 1.7%, recovery rate 99% and positivity rate 6.1% with Shimla having highest CFR 2.5%. Population wise most affected district was Lahul & Spiti with affected population 4.0%.It may be considered as a severe public health threat of this decade. COVID-19 trends, pattern and its analysis will be very important for control and preventive measures.

Mortality of tetanus at the Lagos University Teaching Hospital, Nigeria

2005 ◽  
Vol 35 (3) ◽  
pp. 178-181 ◽  
Author(s):  
F I Ojini ◽  
M A Danesi
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Teaching Hospital ◽  
Case Fatality Rate ◽  
Case Fatality ◽  
Developed Countries ◽  
University Teaching ◽  
Age Group ◽  
Fatality Rate ◽  
Medical Wards

Records of 349 tetanus patients, aged 10 years and above, admitted to the Lagos University Teaching Hospital, Nigeria, between 1990 and 1999 were reviewed. The male:female ratio was 1.98:1, and the ages were between 10 and 88 years, with a mean age of 29.8 years. The overall case fatality rate (CFR) of tetanus was 36.96% (33.19% for men and 44.44% for women). The CFR is similar to that previously reported in the hospital, but higher than that reported from Europe and North America. The lowest CFR was in the 10-19-year age group, and there was a trend towards increasing CFR with increasing age. Tetanus patients in the intensive care unit (ICU) had a significantly higher CFR than those in the medical wards. Unlike in developed countries, where management of tetanus in ICU has resulted in a decrease in CFR, the CFR of tetanus at the Lagos University Teaching Hospital has not significantly reduced over the years.

scholarly journals COVID-19, Australia: Epidemiology Report 20. Fortnightly reporting period ending 5 July 2020

2020 ◽  
Vol 44 ◽  
Author(s):  
Keyword(s):  
Intensive Care ◽  
Vulnerable Populations ◽  
Small Proportion ◽  
Surveillance System ◽  
Case Fatality Rate ◽  
Severe Disease ◽  
Case Fatality ◽  
Fatality Rate ◽  
Notifiable Diseases ◽  
The Past

Notified cases of COVID-19 and associated deaths reported to the National Notifiable Diseases Surveillance System (NNDSS) to 5 July 2020. Cumulative confirmed cases in Australia notified up to 5 July 2020: notifications = 8,566, deaths = 106. Over the past fortnightly reporting period (22 June to 5 July), 897 cases were notified, with 4 deaths. The national incidence of COVID-19 remained low, with very few cases reported by most jurisdictions in this reporting period. The majority of the current cases reported over this fortnight are from Victoria, with an increasing number and proportion of cases reported as being locally acquired. Total case numbers have increased with an average of 54 cases reported on any one day, more than twice the average number reported in the previous reporting period. The number and proportion of deaths associated with COVID-19 remains low and it appears that vulnerable populations have not been disproportionately affected by COVID-19 overall. Testing rates continue to be high across all jurisdictions, with the nationwide positivity rate remaining very low at less than 0.3%. In this reporting period, the number of cases reported nationally has increased from 214 (8 June to 21 June) to 897 (22 June to 5 July). Of the cases notified in this reporting period, 87% (781 cases) were notified from Victoria and 89% of these cases were acquired locally. Of the remaining 116 cases reported from other jurisdictions only 6% were locally acquired. The increase in Victoria is attributable to multiple epidemiologically linked outbreaks across a range of settings and locations. A small proportion of cases have experienced severe disease, requiring hospitalisation or intensive care, with some fatalities. The crude case fatality rate amongst Australian cases is 1.2%. People who are older and have one or more comorbidities are more likely to experience severe disease.

VENTILATOR ASSOCIATED PNEUMONIA IN INTENSIVE CARE UNIT OF A TERTIARY LEVEL HOSPITAL

2021 ◽  
pp. 21-24
Author(s):  
J. D. Bhalerao ◽  
R.M. Tambey
Keyword(s):  
Risk Factors ◽  
Mechanical Ventilation ◽  
Intensive Care ◽  
Case Fatality Rate ◽  
Prolonged Mechanical Ventilation ◽  
Case Fatality ◽  
Tertiary Level ◽  
Ventilator Associated Pneumonia ◽  
Fatality Rate ◽  
Level Hospital

Background: Ventilator associated pneumonia (VAP) is the most common nosocomial infection diagnosed in the intensive care units (ICUs). Hence the present study was undertaken to study the incidence, risk factors, case fatality rate of ventilator associated events (VAE) and VAP in ICU of a tertiary level hospital. Method: Total 100 patient of either sex, having the age of >18 years and who was received mechanical ventilation more than 48 hrs for any indication over a period of 12-18 months in an ICU of a tertiary level hospital were studied. Results: The incidence of VAP was 38.0% and VAP rate was 59.6/1000 ventilator days. Post op status (71%) and trauma (22%) were the most common risk factors which lead to VAP and VAE. Acinetobacter spp (19%) and Klebsiella spp (12%) were the two most common microorganisms causing VAP. Mortality or case fatality rate was 42.10%. In ventilator associated events, 45% patients developed VAC (Ventilator associated condition), 44% patients developed IVAC ( Infection related Ventilator associated condition) and 38% patients developed possible VAP. Conclusion: VAP is a serious problem in the ICU leading to longer hospital stay higher treatment costs and increased mortality and morbidity. Prolonged mechanical ventilation is an important risk factor.

scholarly journals Mortality risk factors show similar trends in modern and historic populations exposed to plague

2016 ◽  
Vol 10 (05) ◽  
pp. 488-493 ◽  
Author(s):  
Mauro Rubini ◽  
Emanuela Gualdi-Russo ◽  
Vanessa S. Manzon ◽  
Natascia Rinaldo ◽  
Raffaella Bianucci
Keyword(s):  
Risk Factors ◽  
Young Adults ◽  
Case Fatality Rate ◽  
Age Groups ◽  
Case Fatality ◽  
Fatality Rate ◽  
Risk Of Mortality ◽  
Three Samples ◽  
Poor Nutrition ◽  
European Populations

Introduction: Plague has been responsible for two major historic pandemics (6th–8th century CE; 14th–19th century CE) and a modern one. The recent Malagasy plague outbreaks raised new concerns on the deadly potential of the plague-causing bacteria Yersinia pestis. Between September 2014 and April 2015, outbreaks of bubonic and pneumonic plague hit the Malagasy population. Two hundred and sixty-three cases, including 71 deaths, have been reported in 16 different districts with a case fatality rate of 27%. The scope of our study was to ascertain whether the risk factors for health in modern-day populations exposed to plague and in ancient populations that faced the two historic pandemics varied or remained substantially unaltered. Methodology: The risk of mortality of the Malagasy population with those obtained from the reconstruction of three samples of European populations exposed to the historic pandemics was contrasted. Results: The evidence shows that the risks of death are not uniform across age neither in modern nor in historic populations exposed to plague and shows precise concentrations in specific age groups (children between five and nine years of age and young adults). Conclusions: Although in the post-antibiotic era, the fatality rates have drastically reduced, both modern and historic populations were exposed to the same risk factors that are essentially represented by a low standard of environmental hygiene, poor nutrition, and weak health systems.

scholarly journals Age, Multiple Chronic Conditions, and COVID-19: A literature review

2020 ◽  
Author(s):  
Mayra Tisminetzky ◽  
Christopher Delude ◽  
Tara Hebert ◽  
Catherine Carr ◽  
Robert J Goldberg ◽  
...  
Keyword(s):  
Chronic Conditions ◽  
Case Fatality Rate ◽  
Age Groups ◽  
Case Fatality ◽  
Multiple Chronic Conditions ◽  
Fatality Rate ◽  
Inclusion Criteria ◽  
Increased Risk ◽  
Poor Outcomes ◽  
The Impact

Abstract Background Various patient demographic and clinical characteristics have been associated with poor outcomes for individuals with coronavirus disease 2019 (COVID-19). To describe the importance of age and chronic conditions in predicting COVID-19 related outcomes. Methods Search strategies were conducted in PubMed/MEDLINE. Daily alerts were created. Results A total of 28 studies met our inclusion criteria. Studies varied broadly in sample size (n=21 to more than 17,000,000). Participants mean age ranged from 48 years to 80 years and the proportion of male participants ranged from 44%-82%. The most prevalent underlying conditions in patients with COVID-19 were hypertension (range: 15% - 69%), diabetes (8% - 40%), cardiovascular disease (4% - 61%), chronic pulmonary disease (1% - 33%), and chronic kidney disease (range 1% - 48%). These conditions were each associated with an increased in-hospital case fatality rate ranging from 1% to 56%. Overall, older adults have a substantially higher case fatality rate (CFR) as compared with younger individuals affected by COVID-19 (42% for those <65 vs 65% > 65 years ). Only one study examined the association of chronic conditions and the risk of dying across different age groups; their findings suggested similar trends of increased risk in those < 65 and those > 65 years as compared to those without these conditions. Conclusions There has been a traditional, single condition approach to consideration of how chronic conditions and advancing age relate to COVID-19 outcomes. A more complete picture of the impact of burden of multimorbidity and advancing patient age is needed.

scholarly journals COVID-19 in Conflict Border Regions: A Case of South Kordofan, Sudan

2021 ◽  
Author(s):  
Quraish Sserwanja ◽  
Mohammed Bashir Adam ◽  
Joseph Kawuki ◽  
Emmanuel Olal
Keyword(s):  
Case Fatality Rate ◽  
Case Fatality ◽  
Fatality Rate ◽  
Mechanical Ventilators ◽  
Governmental Organizations ◽  
Non Governmental Organizations ◽  
Displaced People ◽  
Set Up ◽  
Novel Coronavirus ◽  
South Kordofan

Abstract The novel coronavirus disease (COVID-19) was first reported in Sudan on 13 March 2020. Since then, Sudan has experienced one of the highest COVID-19 spread and fatalities in Africa. As per 12 December 2020, Sudan had a total of 21,591 cases, 1,355 cumulative deaths at a case fatality rate (CFR) of 6.28%. South Kordofan State has 17.4% COVID-19 case fatality rate, the fifth highest rate among the 18 States. The State is home to over 200,000 poor and displaced people from years of destructive civil unrests. To date, several localities such as the Nubba mountains region remain under rebel control and are not accessible. South Kordofan State Ministry of Health in collaboration with the federal government and non-governmental organizations set up four isolation centres with 40 total bed capacity, but with only two mechanical ventilators and no testing centre. There is still need for further multi-sectoral coalition and equitable allocation of resources to strengthen the health systems of rural and conflict affected regions. This article aims at providing insight into the current State of COVID-19 in South Kordofan amidst the second wave to address the dearth of COVID-19 information in rural and conflict affected regions.

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