scholarly journals Geometrical Influence on Particle Transport in Cross-Flow Ultrafiltration: Cylindrical and Flat Sheet Membranes

Membranes ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 960
Author(s):  
Gun Woo Park ◽  
Gerhard Nägele
Keyword(s):  
Particle Transport ◽  
Colloidal Particles ◽  
Hard Spheres ◽  
Scale Up ◽  
Cross Flow ◽  
Permeate Flux ◽  
Permeable Membrane ◽  
Process Indicators ◽  
Flat Sheet ◽  
Membrane Geometry

Cross-flow membrane ultrafiltration (UF) is used for the enrichment and purification of small colloidal particles and proteins. We explore the influence of different membrane geometries on the particle transport in, and the efficiency of, inside-out cross-flow UF. For this purpose, we generalize the accurate and numerically efficient modified boundary layer approximation (mBLA) method, developed in recent work by us for a hollow cylindrical membrane, to parallel flat sheet geometries with one or two solvent-permeable membrane sheets. Considering a reference dispersion of Brownian hard spheres where accurate expressions for its transport properties are available, the generalized mBLA method is used to analyze how particle transport and global UF process indicators are affected by varying operating parameters and the membrane geometry. We show that global process indicators including the mean permeate flux, the solvent recovery indicator, and the concentration factor are strongly dependent on the membrane geometry. A key finding is that irrespective of the many input parameters characterizing an UF experiment and its membrane geometry, the process indicators are determined by three independent dimensionless variables only. This finding can be very useful in the design, optimization, and scale-up of UF processes.

scholarly journals Cross-Flow Microfiltration of Glycerol Fermentation Broths with Citrobacter freundii

Membranes ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 67 ◽  
Author(s):  
Wirginia Tomczak ◽  
Marek Gryta
Keyword(s):  
Colloidal Particles ◽  
Ceramic Membrane ◽  
Fermentation Broth ◽  
Cross Flow ◽  
Transmembrane Pressure ◽  
Citrobacter Freundii ◽  
Permeate Flux ◽  
Glycerol Fermentation ◽  
Fermentation Broths ◽  
The Impact

This paper reports the study of the cross-flow microfiltration (MF) of glycerol fermentation broths with Citrobacter freundii bacteria. A single channel tubular ceramic membrane with a nominal pore size of 0.14 µm was used. It has been demonstrated that the MF ceramic membrane has been successfully applied to bacteria cell removal and to effectively eliminate colloidal particles from glycerol fermentation broths. However, due to fouling, the significant reduction of the MF performance has been demonstrated. In order to investigate the impact of transmembrane pressure (TMP) and feed flow rate (Q) on MF performance, 24 experiments have been performed. The highest steady state permeate flux (138.97 dm3/m2h) was achieved for 0.12 MPa and 1000 dm3/h. Fouling analysis has been studied based on the resistance-in series model. It has been found that the percentage of irreversible fouling resistance during the MF increases with increasing TMP and Q. The permeate flux regeneration has been achieved by membrane cleaning with 3 wt % NaOH and 3 wt % H3PO4 at 45 °C. The results of this study are expected to be useful in industrially employing the MF process as the first step of glycerol fermentation broth purification.

Solid Lipid Nanoparticles: A Promising Drug Delivery Technology

2009 ◽  
Vol 2 (2) ◽  
pp. 509-516
Author(s):  
S. Pragati ◽  
S. Kuldeep ◽  
S. Ashok ◽  
M. Satheesh
Keyword(s):  
Drug Delivery ◽  
Solid Lipid Nanoparticles ◽  
Large Scale ◽  
Colloidal Particles ◽  
Scale Up ◽  
Lipid Nanoparticles ◽  
Scale Production ◽  
Research Activity ◽  
New Approach ◽  
Solid Lipid

One of the situations in the treatment of disease is the delivery of efficacious medication of appropriate concentration to the site of action in a controlled and continual manner. Nanoparticle represents an important particulate carrier system, developed accordingly. Nanoparticles are solid colloidal particles ranging in size from 1 to 1000 nm and composed of macromolecular material. Nanoparticles could be polymeric or lipidic (SLNs). Industry estimates suggest that approximately 40% of lipophilic drug candidates fail due to solubility and formulation stability issues, prompting significant research activity in advanced lipophile delivery technologies. Solid lipid nanoparticle technology represents a promising new approach to lipophile drug delivery. Solid lipid nanoparticles (SLNs) are important advancement in this area. The bioacceptable and biodegradable nature of SLNs makes them less toxic as compared to polymeric nanoparticles. Supplemented with small size which prolongs the circulation time in blood, feasible scale up for large scale production and absence of burst effect makes them interesting candidates for study. In this present review this new approach is discussed in terms of their preparation, advantages, characterization and special features.

A study on the fouling phenomena of a microfiltration membrane

2004 ◽  
Vol 4 (5-6) ◽  
pp. 223-231
Author(s):  
H.-H. Yeh ◽  
W.-H. Wang
Keyword(s):  
Salicylic Acid ◽  
Humic Acid ◽  
Calcium Ion ◽  
Colloidal Particles ◽  
Alginic Acid ◽  
Particle System ◽  
Feed Water ◽  
Permeate Flux ◽  
Widespread Application ◽  
Latex Beads

The utilization of membrane processes for drinking water treatment has become more popular. However, fouling by source water probably is the major factor prohibits its widespread application. In this research, the fouling phenomena of a microfiltration (MF) membrane were studied. The interactions among colloidal particles, calcium ion, and dissolved organics, such as salicylic acid, humic acid, and alginic acid, on MF fouling were focused. A lab-scale single hollow fiber MF membrane, made of polyvinylidenefluoride (PVDF), module was used. The results show that, for single organic compound, the extent of fouling caused by humic acid was higher that of alginic acid. For the latter, the permeate flux decrease at lower pH was more significant than those at higher pH. For low MW salicylic acid, both rejection and flux decrease were minor. It seems that solubility have strong correlation with fouling rate. The higher the solubility is, the lower the fouling rate. For sole colloidal particle system, latex beads with diameter close to the pore size of MF membrane showed severe fouling. Adding Ca can aggregate the latex beads, and alleviate fouling. However, calcium ion also found to increase fouling of alginic acid on membrane under neutral or alkali pH condition, probably via charge neutralization and/or bridging. In conclusion, MF fouling seems to be strongly related to the type of organics, size of colloidal particles, and the existence of divalent ions, in the feed water.

Effect of Fluidized Bed on Permeate Flux in Ceramic Membrane Cross-Flow Microfiltration

1995 ◽  
Vol 60 (12) ◽  
pp. 2074-2084
Author(s):  
Petr Mikulášek
Keyword(s):  
Fluidized Bed ◽  
Ceramic Membrane ◽  
Cross Flow ◽  
Experimental System ◽  
Experimental Results ◽  
Spherical Particles ◽  
Permeate Flux ◽  
Model Fluid ◽  
Optimum Porosity ◽  
Tubular Membranes

The microfiltration of a model fluid on an α-alumina microfiltration tubular membrane in the presence of a fluidized bed has been examined. Following the description of the basic characteristic of alumina tubular membranes, model dispersion and spherical particles used, some comments on the experimental system and experimental results for different microfiltration systems are presented. From the analysis of experimental results it may be concluded that the use of turbulence-promoting agents resulted in a significant increase of permeate flux through the membrane. It was found out that the optimum porosity of fluidized bed for which the maximum values of permeate flux were reached is approximately 0.8.

scholarly journals Clarification Processes of Orange Prickly Pear Juice (Opuntia spp.) by Microfiltration

Membranes ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 354
Author(s):  
Jaime A. Arboleda Mejia ◽  
Jorge Yáñez-Fernandez
Keyword(s):  
Suspended Solids ◽  
Cross Flow ◽  
Laboratory Scale ◽  
Prickly Pear ◽  
Permeate Flux ◽  
Color Properties ◽  
Pear Juice ◽  
Opuntia Spp

In this study, fresh orange prickly pear juice (Opuntia spp.) was clarified by a cross-flow microfiltration (MF) process on a laboratory scale. The viability of the process—in terms of productivity (permeate flux of 77.80 L/h) and the rejection of selected membranes towards specific compounds—was analyzed. The quality of the clarified juice was also analyzed for total antioxidants (TEAC), betalains content (mg/100 g wet base), turbidity (NTU) and colorimetry parameters (L, a*, b*, Croma and H). The MF process permitted an excellent level of clarification, reducing the suspended solids and turbidity of the fresh juice. In the clarified juice, a decrease in total antioxidants (2.03 TEAC) and betalains content (4.54 mg/100 g wet basis) was observed as compared to the fresh juice. Furthermore, there were significant changes in color properties due to the effects of the L, a*, b*, C and h° values after removal of turbidity of the juice. The turbidity also decreased (from 164.33 to 0.37 NTU).

scholarly journals Data-driven Modelling of Microfiltration Process with Embedded Static Mixer for Steepwater from Corn Starch Industry

2017 ◽  
Author(s):  
Laslo Šereš ◽  
Ljubica Dokić ◽  
Bojana Ikonić ◽  
Dragana Šoronja-Simović ◽  
Miljana Djordjević ◽  
...  
Keyword(s):  
Corn Starch ◽  
Desirability Function ◽  
Specific Energy Consumption ◽  
Cross Flow ◽  
Operating Conditions ◽  
Transmembrane Pressure ◽  
Static Mixer ◽  
Permeate Flux ◽  
Experimental Conditions ◽  
Starch Industry

Cross-flow microfiltration using ceramic tubular membrane was applied for treatment of steepwater from corn starch industry. Experiments are conducted according to the faced centered central composite design at three different transmembrane pressures (1, 2 and 3 bar) and cross-flow velocities (100, 150 and 200 L/h) with and without the usage of Kenics static mixer. For examination of the influence of the selected operating conditions at which usage of the static mixer is justified, a response surface methodology and desirability function approach were used. Obtained results showed improvement in the average permeate flux by using Kenics static mixer for 211 % to 269 % depending on experimental conditions when compared to the system without the static mixer. As a result of optimization, the best results considering flux improvement as well as reduction of specific energy consumption were obtained at low transmembrane pressure and lower feed cross-flow rates.

Electrokinetic Power Generation by Forward Osmosis

2012 ◽  
Author(s):  
Kar Cherng Hon ◽  
Chun Yang ◽  
Seow Chay Low
Keyword(s):  
Power Generation ◽  
Salinity Gradient ◽  
Forward Osmosis ◽  
Streaming Potential ◽  
Nacl Solution ◽  
Direct Power ◽  
Concentration Difference ◽  
Permeable Membrane ◽  
Flat Sheet ◽  
Novel Method

In this paper, an innovative direct power generation technique from salinity gradient is proposed and demonstrated. The basis of this novel method encompasses forward osmosis (FO) and electrokinetic (EK) principles. Tapping the concentration difference between seawater and river fresh water, forward osmosis (FO) is utilized to allow for spontaneously transporting water across a semi-permeable membrane. The flow of water is then directed towards array of microchannels in the form of porous medium where power is produced from the electrokinetical streaming potential. Experimentally, NaCl solution and DI water were used to model as seawater and fresh river water, respectively. Both glass and polymer based porous media and commercial flat sheet FO membranes were employed herein. Results show power density could reach the order of 101W/m2. Having features of ease of fabrication, simple configuration and no mechanical moving parts, this method provides a feasible mean to harvest enormous energy from salinity gradient. Thus the proposed technique could contribute greatly to renewable energy and towards sustainable future.

Concentration and Desalination of Protein Derived from Tuna Cooking Juice by Nanofiltration

2013 ◽  
Vol 65 (4) ◽  
Author(s):  
Muhammadameen Hajihama ◽  
Wirote Youravong
Keyword(s):  
Membrane Filtration ◽  
Protein Concentration ◽  
Protein Hydrolysate ◽  
Salt Content ◽  
Cross Flow ◽  
Transmembrane Pressure ◽  
Permeate Flux ◽  
Batch Mode ◽  
Additional Process ◽  
Canning Industry

Tuna cooking juice is a co-product of tuna canning industry. It riches in protein, currently used for production of feed meal as well as protein hydrolysate. The finish products are usually in the form of concentrate, produced by evaporation process. However, evaporation is energy consumable process and the salt content level of the concentrate is often over the standard, thus required additional process for lowering salt content e.g. crystallization. The use of membrane technology, therefore, is of interest, since it required less energy and footprint compared with evaporation and is also able to reduce salt content of the concentrate. The aim of this study were to employ and select the membrane filtration process, and optimize the operating condition for protein concentration and desalination of tuna cooking juice. The results indicated that nanofiltration (NF) was more suitable than the ultrafiltration (UF) process, regarding the ability in protein recovery and desalination. The NF performance was evaluated in terms of permeation flux and protein and salt retentions. The protein and salt rejections of NF were 96 % and 5 %, respectively. The permeate flux(J) increased as transmembrane pressure (TMP) or cross flow rate (CFR) increased and the highest flux was obtained at TMP of 10 bar and CFR of 800 L/h. Operating with batch mode, the permeate flux was found to decrease as protein concentration increased, and at volume concentration factor about 4, the protein concentration  about 10% while salt removal was aproximately 70 % of the initial value. This work clearly showed that NF was successfully employed for concentration and desalination of protein derived from tuna cooking juice.

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