Direct Photoexcitation of Benzothiazolines: Acyl Radical Generation and Application to Access Heterocycles
Keyword(s):
An acyl radical generation and functionalization strategy through direct photoexcitation of benzothiazolines has been developed. The formed acyl radical species can either be trapped by quinoxalin-2-ones to realize their C(3)-H functionalization or trigger a cascade radical cyclization with isonitriles to synthesise biologically important phenanthridines. The synthetic value of this protocol can be further illustrated by the modification of quinoxalin-2-ones, containing important natural products and drug-based complex molecules.
Keyword(s):
Expedient Access to Enantiopure Cyclopentanic Natural Products: Total Synthesis of (-)-Cyclonerodiol
2015 ◽
Vol 10
(1)
◽
pp. 1934578X1501000
Keyword(s):
2009 ◽
Vol 81
(6)
◽
pp. 1075-1084
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