scholarly journals Central But Not General Obesity Is Positively Associated with the Risk of Hyperhomocysteinemia in Middle-Aged Women

Nutrients ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1614 ◽  
Author(s):  
Yingying Wang ◽  
Yonggen Jiang ◽  
Na Wang ◽  
Meiying Zhu ◽  
Xing Liu ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Regression Models ◽  
Central Obesity ◽  
Multiple Logistic Regression ◽  
Obese Women ◽  
General Obesity ◽  
Middle Aged ◽  
Logistic Regression Models ◽  
Serum Homocysteine ◽  
The Mean

Objective: Obesity and homocysteine (Hcy) are two important risk factors for cardiovascular disease (CVD). However, evidence on the association between obesity and Hcy concentration was conflicting. The aim of our study is to explore the associations of general and central obesity with hyperhomocysteinemia (HHcy) in middle-aged women. Methods: The current analysis was based on data from 11,007 women aged 40–60 years. Height, weight, and waist circumference (WC) were measured and serum homocysteine was determined. Multiple logistic regression models were used to assess the associations of the risk of hyperhomocysteinemia (HHcy, Hcy > 15 μmol/L) with BMI and WC. Results: 13.71% women had HHcy. The prevalences of BMI-based general obesity and WC-based central obesity were 11.17% and 22.88%, respectively. Compared with non-obese women, the mean serum Hcy concentration was significantly higher in WC-based central obese women (p = 0.002), but not in BMI-based general obese women (p > 0.05). In the multiple logistic regression models, central obesity was positively related to the risk of HHcy (OR = 1.30, 95% CI = 1.10 to 1.52), while general obesity was inversely related to the risk of HHcy (OR = 0.82, 95% CI = 0.72 to 0.93 and OR = 0.71, 95% CI = 0.57 to 0.89). Conclusions: Central obesity was positively related to the risk of HHcy, while general obesity was negatively related. Menopause showed no effect modification on these associations.

scholarly journals 1400Central but not general obesity is positively associated with risk of hyperhomocysteinemia in middle-aged women

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Yingying Wang
Keyword(s):  
Cardiovascular Disease ◽  
Logistic Regression ◽  
Regression Models ◽  
Central Obesity ◽  
Multiple Logistic Regression ◽  
Obese Women ◽  
General Obesity ◽  
Middle Aged ◽  
Logistic Regression Models ◽  
The Relationship

Abstract Background Obesity and homocysteine (Hcy) are two important risk factors for cardiovascular disease (CVD); however, there were conflicting results for the relationship between them. Our study is to explore the associations of general and central obesity with hyperhomocysteinemia (HHcy) in middle-aged women. Methods The current analysis was based on data from 11007 women aged 40-60 years. Height, weight, and waist circumference (WC) were measured and serum homocysteine was determined. Multiple logistic regression models were used to assess the associations of the risk of hyperhomocysteinemia (HHcy, Hcy>15μmol/L) with BMI and WC. Results 13.71% women had HHcy. The prevalences of BMI-based general obesity and WC-based central obesity were 11.17% and 22.88%, respectively. Compared with non-obese women, the mean serum Hcy concentration was significantly higher in WC-based central obese women (P = 0.002), but not in BMI-based general obese women (P > 0.05). In the multiple logistic regression models, central obesity was positively related to the risk of HHcy (OR = 1.30, 95%CI=1.10 to 1.52), while general obesity was inversely related to the risk of HHcy (OR = 0.82, 95%CI=0.72 to 0.93 and OR = 0.71,95% CI = 0.57 to 0.89). Conclusions Central obesity was positively, while general obesity was negatively related to the risk of HHcy. Menopause showed no effect modification on these associations. Key messages Homocysteine; Central obesity; Menopause; Cardiovascular Disease

scholarly journals Aplicación de modelos de regresión logística en metodología observacional: modalidades de competición en la iniciación al fútbol.

2015 ◽  
Vol 32 (1) ◽  
pp. 288 ◽  
Author(s):  
Daniel Lapresa ◽  
Javier Arana ◽  
M.Teresa Anguera ◽  
J.Ignacio Pérez-Castellanos ◽  
Mario Amatria
Keyword(s):  
Physical Activity ◽  
Logistic Regression ◽  
Regression Model ◽  
Regression Models ◽  
Logistic Regression Model ◽  
Multiple Logistic Regression ◽  
Observational Methodology ◽  
Logistic Regression Models ◽  
Game Format ◽  
Simple Logistic

This study shows how simple and multiple logistic regression can be used in observational methodology and more specifically, in the fields of physical activity and sport. We demonstrate this in a study designed to determine whether three-a-side futsal or five-a-side futsal is more suited to the needs and potential of children aged 6-to-8 years. We constructed a multiple logistic regression model to analyze use of space (depth of play) and three simple logistic regression models to determine which game format is more likely to potentiate effective technical and tactical performance.

scholarly journals 1402Thyroid stimulating hormone (TSH) is associated with general and abdominal obesity in girls during puberty

2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Yingying Wang
Keyword(s):  
Logistic Regression ◽  
Abdominal Obesity ◽  
Regression Models ◽  
Population Based ◽  
Thyroid Stimulating Hormone ◽  
General Obesity ◽  
Logistic Regression Models ◽  
The Impact ◽  
Serum Tsh ◽  
Stimulating Hormone

Abstract Background Childhood is an important public health issue. Although both thyroid hormone and menarche are known to play a role in body metabolism and energy expenditure, no population-based study has been conducted to investigate the impact of TSH on adipogenesis among population-based girls around puberty. Methods A multi-stage cluster sampling method was used to select one junior middle school from each of 4 study areas: Minhang District in Shanghai, Haimen City in Jiangsu Province, Yuhuan City and Deqing County in Zhejiang Province. A total of 474 girls aged 11 to 14 years from 4 schools were enrolled. Information on demographic factors and puberty stage were collected, and anthropometric measurements and thyroid hormones were determined. Multivariate logistic regression models were used to assess the associations of Thyroid stimulating hormone (TSH) with the risk of obesity measured by body mess index (BMI) and waist circumference (WC). Results Of the 474 girls, the prevalences of BMI-based general obesity and WC-based abdominal obesity were 19.8% (94/474) and 21.7% (103/474), respectively. Compared with normal weight girls, the mean serum TSH concentration was significantly higher in BMI-based general overweight or obese girls (P = 0.037), but not in WC-based central overweight or obese girls (P = 0.173). In the multiple logistic regression models, for girls with highest tertile of serum TSH concentration relative to those in the lowest tertile, the odds ratios were 2.58 (95% CI 1.32 to 5.04) and 2.50 (95% CI 1.30 to 4.81) for overweight or obesity based on BMI and WC after adjustment for puberty stage and other covariates. Conclusions Serum TSH concentration was positively associated with both general and abdominal obesity in school-age girls and the association was independent of puberty. Key messages thyroid stimulating hormone; general obesity; central obesity; school-aged girls; puberty

Use of Logistic Regression for Developing Risk-adjusted Quality Indicators in Nursing

2010 ◽  
Vol 49 (06) ◽  
pp. 608-612 ◽  
Author(s):  
D. Renner ◽  
B. Fischer ◽  
M. Kutschmann
Keyword(s):  
Risk Factors ◽  
Logistic Regression ◽  
Quality Indicators ◽  
Regression Models ◽  
Pressure Ulcers ◽  
Logistic Function ◽  
Multiple Logistic Regression ◽  
Logistic Regression Models ◽  
Joint Influence ◽  
Developed Pressure

Summary Objectives: A low rate of newly developed pressure ulcers is considered as an important quality indicator in nursing. However, the result of a hospital depends not only on the quality of care but on the risk profile of its patients as well. Therefore, based on multiple logistic regression models we describe a method for calculating risk-adjusted quality indicators in nursing. Method: Based on data of 1,009,989 patients from 1747 hospitals in 2009, we developed two multiple logistic regression models to identify and to weigh a possible joint influence of several risk factors on newly developed pressure ulcers. In a further step, we calculated risk-adjusted rates. Results: Factors remaining in the regression models were “micro-movements on admission”, “diabetes mellitus”, “age” and “days on intensive care unit”. Based on the corresponding regression coefficients and the logistic function, the expected rate of newly developed pressure ulcers was calculated for every hospital. Fi nally, expected rates and observed rates both were used to calculate risk-adjusted rates. Conclusion: The simultaneous consideration of relevant risk factors by means of risk- adjusted quality indicators ensures a fair comparison of hospitals.

scholarly journals THE MODE CHOICES AND COMMUTING STRESS: EMPIRICAL EVIDENCE FROM JAKARTA AND DENPASAR

2019 ◽  
Vol 7 (1) ◽  
pp. 68
Author(s):  
Ismatulloh Rosida ◽  
Dyah Wulan Sari ◽  
Amelia Dertta Irjayanti
Keyword(s):  
Logistic Regression ◽  
Public Transport ◽  
Regression Models ◽  
Toll Roads ◽  
Multiple Logistic Regression ◽  
Logistic Regression Models ◽  
High Impedance ◽  
Logistic Regressions ◽  
Using Data ◽  
The Relationship

Jabodetabek and Sarbagita have the highest worker commuter population in Indonesia. However, Jabodetabek has various and larger coverage of public transport than Sarbagita. This study also analyzes the relationship between the usage of specific transport modes and commuting stress. Multiple logistic regression models have been estimated using data of both Jabodetabek Commuter Survey and Sarbagita Commuter Survey. Using logistic regressions, the results show that mode choices, gender, and travel time have a significant effect on commuting stress. The analysis also indicates that both in high impedance and low impedance metropolitans, car commuting is perceived to be more stressful than non-car commuting. In a condition of restricted mode choices, commuters who use cars have a greater probability of commuting stress. Furthermore, the findings of this study imply limitation of car usage and as an evaluation of the policy of opening toll roads as a solution to urban congestion.

scholarly journals The Association of Sleep Duration With Vision Impairment in Middle-Aged and Elderly Adults: Evidence From the China Health and Retirement Longitudinal Study

2021 ◽  
Vol 8 ◽  
Author(s):  
Mengsha Sun ◽  
Qiyu Bo ◽  
Bing Lu ◽  
Xiaodong Sun ◽  
Minwen Zhou
Keyword(s):  
Logistic Regression ◽  
Longitudinal Study ◽  
Sleep Duration ◽  
Regression Models ◽  
Vision Impairment ◽  
Multilevel Logistic Regression ◽  
Elderly Adults ◽  
Middle Aged ◽  
Logistic Regression Models ◽  
Long Sleep

Objective: This study aims to investigate the association of sleep duration with vision impairment (VI) in middle-aged and elderly adults.Methods: This cross-sectional study used the data from the baseline survey of the China Health and Retirement Longitudinal Study (CHARLS) 2011–2012, a national survey of adults aged 45 years or older. Weighted multilevel logistic regression models were used to evaluate the association between self-reported sleep duration and VI.Results: Of the 13,959 survey respondents, a total of 4,776 (34.2%) reported VI. The prevalence of short (≤6 h/night) and long (>8 h/night) sleep durations was higher among respondents with VI than those without VI (P < 0.001). Multilevel logistic regression models showed that compared with a sleep duration of 6–8 h/night, a sleep duration of ≤6 h/night was associated with a 1.45-fold [95% confidence interval (CI) = 1.34–1.56] higher VI risk, and a sleep duration of >8 h/night was associated with a 1.18-fold (95% CI = 1.03–1.34) higher VI risk, after adjusting for sociodemographic data, lifestyle factors, and health conditions. Vision impairment was associated with short sleep duration in respondents from all age or gender categories. However, VI was associated with long sleep duration in respondents from the elderly or female categories. The association between VI and long sleep duration disappeared in respondents of middle-aged or male categories.Conclusions: The potential impact of sleep on the risk of visual functions requires further attention. A more comprehensive and integrated health care and rehabilitation system covering vision and sleep is also needed.

scholarly journals Association of biomass fuel smoke with respiratory symptoms among children under 5 years of age in urban areas: results from Bangladesh Urban Health Survey, 2013

2019 ◽  
Vol 24 (1) ◽  
Author(s):  
Md. Hasan ◽  
Sadia Tasfina ◽  
S. M. Raysul Haque ◽  
K. M. Saif-Ur-Rahman ◽  
Md. Khalequzzaman ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Urban Health ◽  
Health Survey ◽  
Regression Models ◽  
Respiratory Symptoms ◽  
Smoke Exposure ◽  
Biomass Fuel ◽  
Multiple Logistic Regression ◽  
Logistic Regression Models ◽  
Children Under 5

Abstract Background Little is known regarding the effect of exposure to biomass fuel smoke inhalation on respiratory symptoms in the Bangladeshi population which is a major health hazard in most of the developing countries. This study aims to explore the association between respiratory symptoms and biomass fuel smoke exposure among children under 5 years of age. Methods Data were extracted from the Bangladesh Urban Health Survey conducted in 2013. A total of 10,575 mothers with at least one surviving children were selected. Respiratory symptoms among children under 5 years of age were considered as the primary outcome. Sequential multiple logistic regression models were used to observe the association between respiratory symptoms and biomass fuel smoke exposure adjusting the effect of residential factors and mother and child characteristics. Results Around 40% of the mothers exclusively used biomass fuel irrespective of the kitchen location and 54% of them were habituated in indoor cooking. The prevalence of respiratory symptoms of under-five children among in-house and outdoor biomass fuel users was 23.0% and 21.9%, respectively. Results of fitted multiple logistic regression models showed that the odds of having respiratory symptoms among children under 5 years of age were increased due to in-house biomass fuel use [OR = 1.18; 95% CI, 1.04–1.36] compared with the non-biomass user. An increased risk of respiratory symptoms was also significantly associated with mother’s birth complication [OR = 1.51; 95% CI, 1.36–1.67], non-government organization (NGO) membership of mothers [OR = 1.32; 95% CI, 1.16–1.51], age of the child (6–23m) [OR = 1.29; 95% CI, 1.10–1.52], and nutritional status (stunting) [OR = 1.18; 95% CI, 1.06–1.31]. Conclusion This study found the use of in-house biomass fuel as a significant risk factor associated with respiratory symptoms of children under 5 years of age. More longitudinal studies should be designed to establish a causal relationship between HAP (household air pollution) and respiratory symptoms among children with more direct measures of HAP and clinical procedure.

scholarly journals Impact of peer review on discussion of study limitations and strength of claims in randomized trial reports: a before and after study

2019 ◽  
Vol 4 (1) ◽  
Author(s):  
Kerem Keserlioglu ◽  
Halil Kilicoglu ◽  
Gerben ter Riet
Keyword(s):  
Logistic Regression ◽  
Peer Review ◽  
Regression Models ◽  
Randomized Trials ◽  
Median Number ◽  
Logistic Regression Models ◽  
Before And After ◽  
The Mean ◽  
Before And After Study ◽  
Manuscript Publication

Abstract Background In their research reports, scientists are expected to discuss limitations that their studies have. Previous research showed that often, such discussion is absent. Also, many journals emphasize the importance of avoiding overstatement of claims. We wanted to see to what extent editorial handling and peer review affects self-acknowledgment of limitations and hedging of claims. Methods Using software that automatically detects limitation-acknowledging sentences and calculates the level of hedging in sentences, we compared the submitted manuscripts and their ultimate publications of all randomized trials published in 2015 in 27 BioMed Central (BMC) journals and BMJ Open. We used mixed linear and logistic regression models, accounting for clustering of manuscript-publication pairs within journals, to quantify before-after changes in the mean numbers of limitation-acknowledging sentences, in the probability that a manuscript with zero self-acknowledged limitations ended up as a publication with at least one and in hedging scores. Results Four hundred forty-six manuscript-publication pairs were analyzed. The median number of manuscripts per journal was 10.5 (interquartile range 6–18). The average number of distinct limitation sentences increased by 1.39 (95% CI 1.09–1.76), from 2.48 in manuscripts to 3.87 in publications. Two hundred two manuscripts (45.3%) did not mention any limitations. Sixty-three (31%, 95% CI 25–38) of these mentioned at least one after peer review. Changes in mean hedging scores were negligible. Conclusions Our findings support the idea that editorial handling and peer review lead to more self-acknowledgment of study limitations, but not to changes in linguistic nuance.

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