The Manuscript Preparation chapter of the 11th edition of the AMA Manual of Style considers each element of a manuscript (with the exception of references and figures, tables, and boxes, which are dealt with in separate chapters): titles and subtitles, author bylines and end-of-text signatures, notes, running heads and running feet, abstracts, key words, epigraphs, headings and subheadings and side headings, addenda, acknowledgments, appendixes, online-only supplementary material, and ancillary educational and promotional material. Guidance is directed to both authors, for manuscript preparation and submission, and editors, for manuscript publication. Requirements of specific journals as well as reporting guidelines such as EQUATOR are taken into account. For some sections, both print and online examples are provided.