scholarly journals Relationship between Dietary Patterns with Benign Prostatic Hyperplasia and Erectile Dysfunction: A Collaborative Review

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4148
Author(s):  
Giorgio Russo ◽  
Giuseppe Broggi ◽  
Andrea Cocci ◽  
Paolo Capogrosso ◽  
Marco Falcone ◽  
...  
Keyword(s):  
Erectile Dysfunction ◽  
Benign Prostatic Hyperplasia ◽  
Dietary Patterns ◽  
Muscle Tone ◽  
Prostatic Hyperplasia ◽  
Beneficial Effects ◽  
Search Terms ◽  
Regulatory Effects ◽  
English Articles ◽  
The Impact

Interest in the role of dietary patterns has been consistently emerging in recent years due to much research that has documented the impact of metabolism on erectile dysfunction (ED) and/or benign prostatic hyperplasia (BPH). We conducted a non-systematic review of English articles published from 1964 to September 2021. The search terms were: (“dietary patterns” OR “diet”) AND/OR (“erectile dysfunction”) AND/OR (“benign prostatic hyperplasia”). In the present review, we have highlighted how the association between dietary patterns and two of the most frequent pathologies in urology, namely erectile dysfunction and benign prostatic hyperplasia, is present in the literature. The data suggested that a diet that is more adherent to the Mediterranean diet or that emphasizes the presence of vegetables, fruits, nuts, legumes, and fish or other sources of long-chain (n-3) fats, in addition to reduced content of red meat, may have a beneficial role on erectile function. At the same time, the same beneficial effects can be transferred to BPH as a result of the indirect regulatory effects on prostatic growth and smooth muscle tone, thus determining an improvement in symptoms. Certainly, in-depth studies and translational medicine are needed to confirm these encouraging data.

scholarly journals The Impact of Diabetes Type 2 in the Pathogenesis of Benign Prostatic Hyperplasia: A Review

2009 ◽  
Vol 2009 ◽  
pp. 1-3 ◽  
Author(s):  
K. Stamatiou ◽  
M. Lardas ◽  
E. Kostakos ◽  
V. Koutsonasios ◽  
E. Michail
Keyword(s):  
Diabetes Mellitus ◽  
Benign Prostatic Hyperplasia ◽  
Diabetes Mellitus Type 2 ◽  
Diabetes Type 2 ◽  
Prostatic Hyperplasia ◽  
Diabetes Mellitus Type ◽  
Search Terms ◽  
Relationship Of ◽  
The Impact

Introduction. Clinical observation of larger prostate glands in men with diabetes mellitus type 2 led some investigators to hypothesize that an association between these two conditions exists. In fact, both diseases are very common in men as they age and seem to be sharing similar epidemiologic features. Several studies examining the above hypothesis were yielded.Aim. The purpose of this paper is to summarize the existing literature focusing on the coexistence of BPH and diabetes mellitus type 2 and to elucidate whether or not an association among these conditions exists.Methods. We identified studies published from 1990 onwards by searching the MEDLINE database of the National Library of Medicine. Initial search terms werebenign prostatic hyperplasia, epidemiology, andrisk factor,combined withdiet hyperinsulinemia, and diabetes mellitus type 2.Results. Diabetes mellitus type 2 and hyperinsulinemia are quite common conditions and often coexist with BPH. There are several studies (observational, epidemiological, and experimental) examining the association between them in literature.Conclusion. Evidence suggests that an association between BPH and diabetes through a common pathogenic mechanism is possible. The specific pathway interfering in the development of both conditions is still poorly investigated; thus, the exact relationship of BPH to diabetes remains unclear.

Finasteride, not tamsulosin, increases severity of erectile dysfunction and decreases testosterone levels in men with benign prostatic hyperplasia

2015 ◽  
Vol 23 (3) ◽  
Author(s):  
Abdulmaged M. Traish ◽  
Karim Sultan Haider ◽  
Gheorghe Doros ◽  
Ahmad Haider
Keyword(s):  
Erectile Dysfunction ◽  
Benign Prostatic Hyperplasia ◽  
Side Effects ◽  
Adverse Effects ◽  
Erectile Function ◽  
Prostatic Hyperplasia ◽  
Continuous Treatment ◽  
Plasma Testosterone ◽  
The Impact

Abstract5α-reductase inhibitors (5α-RIs) (finasteride and dutasteride) have been proven useful in treatment of lower urinary tract symptoms (LUTS) related to benign prostatic hyperplasia (BPH). However, these inhibitors exert undesirable sexual side effects and, in some cases, these effects are persistent. There is considerable disagreement with regard to whether the adverse side effects resolve with continuous treatment.To investigate the long-term adverse effects of finasteride treatment in men with BPH on erectile function and to compare these adverse effects in men treated with the α1-adrenergic receptor blocker, tamsolusin.In this retrospective registry study, a cohort of 470 men aged between 47 and 68 years (mean 57.78±4.81) were treated with finasteride (5 mg/day). A second cohort of 230 men aged between 52 and 72 years (mean 62.62±4.65) were treated with tamsulosin (0.4 mg). All men were followed up for 45 months. At intervals of 3 months and at each visit, plasma testosterone (T) levels and the international index of erectile function (IIEF-EF) questionnaire scores were determined.Long-term treatment with finasteride therapy is associated with worsening of erectile dysfunction (ED) as shown by the significant decrease in the IIEF-EF scores in men treated with finasteride. No worsening of ED was observed in men treated with tamsulosin. The increase in ED due to finasteride did not resolve with continued treatment with finasteride. Most importantly, long-term finasteride therapy resulted in reduction in total T levels, contributing to a state of hypogonadism. On the contrary, no changes in T levels were noted in men treated with tamsolusin.Our findings suggest that in men with BPH, long-term finasteride therapy but not tamsulosin results in worsening of ED and reduces total T concentrations. Clinicians are urged to discuss the impact of 5α-RIs therapy on sexual function with their patients before commencing this therapy.

scholarly journals The impact of prostate-transurethral resection on erectile dysfunction in benign prostatic hyperplasia

2019 ◽  
Vol Volume 11 ◽  
pp. 91-96
Author(s):  
Anak Agung Gde Oka ◽  
Gede Wirya Kusuma Duarsa ◽  
Putu Astri Novianti ◽  
Tjokorda Gde Bagus Mahadewa ◽  
Christopher Ryalino
Keyword(s):  
Erectile Dysfunction ◽  
Benign Prostatic Hyperplasia ◽  
Transurethral Resection ◽  
Prostatic Hyperplasia ◽  
The Impact

scholarly journals Clinical significance of prostatic-urethral angulation on the treatment outcome of patients with symptomatic benign prostatic hyperplasia treated with tamsulosin hydrochloride

2015 ◽  
Vol 87 (3) ◽  
pp. 238
Author(s):  
Hassan El-Tatawy ◽  
Tarek Gameel ◽  
Mohammed Abo El-enen ◽  
Ayman Hagras ◽  
Ayman Mousa ◽  
...  
Keyword(s):  
Benign Prostatic Hyperplasia ◽  
Clinical Significance ◽  
Treatment Efficacy ◽  
Specific Antigen ◽  
Prostatic Hyperplasia ◽  
Final Conclusion ◽  
P Value ◽  
Significant Difference ◽  
Group A ◽  
The Impact

Objectives: To evaluate the impact of the prostatic-urethral angulation (PUA) on the treatment efficacy of selective alpha-1A receptor blocker in male patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia (LUTS/BPH). Materials and methods: A total of 80 patients with LUTS/BPH and with mean age 53.3 ± 6.3 (range 47-70) were included in our prospective comparative study. The patients were classified into 2 groups as a consecutive cases 40 in each one depending on the PUA either ≤ 35° (group A) or &gt; 35° (group B). PUA and different prostatic parameters were measured using transrectal ultrasound. Prostate-specific antigen (PSA), the International Prostate Symptom Score and quality of life score (IPSS/QoL score), maximum flow rate (Q<sub>max</sub>), and postvoid residual (PVR) volume were compared between the groups. The clinical significance of PUA was evaluated after 8 weeks of medical treatment with tamsulosin hydrochloride 0.4 mg daily. Results: Baseline evaluation (pre-treatment) for both groups were comparable to each other with no clinically significant difference regarding age, PSA, IPSS/QoL score, Qmax and PVR volume (P-value &gt; 0.05). Comparison of parameters after 8 weeks showed that tamsulosin hydrochloride improved the total IPSS and all subscores (P &lt; 0.001), QoL (P = 0.001), Q<sub>max</sub> (P = 0.002), and PVR (P = 0.04) in group A (Table 1). Conclusion: Tamsulosin hydrochloride appears to be less effective in improving IPSS/Qol score, Qmax and PVR in patients with lager PUA. The PUA might be a predictor for the treatment efficacy of α-blockers and more studies are warranted in the future before the final conclusion.

scholarly journals Gambaran disfungsi ereksi pada pasien dengan benign prostatic hyperplasia (BPH) di Klinik Advent Tikala Manado

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Michael B. Tawale ◽  
Lydia Tendean ◽  
Lusiana Setiawati
Keyword(s):  
Erectile Dysfunction ◽  
Benign Prostatic Hyperplasia ◽  
Clinical Signs ◽  
Sampling Technique ◽  
Descriptive Study ◽  
Prostatic Hyperplasia ◽  
Cross Sectional ◽  
Purposive Sampling ◽  
Post Surgery ◽  
Cross Sectional Design

Abstract: Erectile dysfunction (ED) is an inability to achieve an erection sufficient for intercourse with his partner which causes dissatisfaction for both of them. The etiology of ED is classified as psychogenic, organic, drug abuse, and also by post-surgery. Benign prostatic hyperplasia (BPH) is a disease caused by aging. BPH clinical signs usually appear in more than 50% of men aged ≥50 years. This was a survey-descriptive study with a cross sectional design. Samples were obtained by using purposive sampling technique. Respondents were patients at Efrata Adventist Clinic in Manado. The instrument in this study was modified IIEF-5 questionnaire. The results showed that based on the duration of BPH, respondents who suffered from BPH >3 years were as many as 75.0% and <1 year were 7.1%. Based on the ages, respondents of 61-70 years were 46.5 and of 41-50 years were 7.1%. The erectile dysfunction of respondents was classified as moderate 42.9%, mild-moderate 32.1%, severe 17.9%, and mild 7.1%. Conclusion: Most of the erectile dysfunction with BPH >3 years was classified as moderate.Keywords: erectile dysfunction, BPH Abstrak: Disfungsi ereksi (DE) yaitu suatu ketidakmampuan untuk mencapai ereksi yang cukup untuk melakukan senggama bersama pasangannya sehingga menimbulkan ketidakpuasan diantara keduanya. Etiologi DE diklasifikasikan menjadi psikogenik, organik, penyalahgunaan obat-obatan dan juga oleh pasca tindakan bedah. Benign prostatic hyperplasia (BPH) adalah penyakit yang disebabkan oleh penuaan. Tanda klinis BPH biasanya muncul pada lebih dari 50% laki-laki yang berusia 50 tahun ke atas. Jenis penelitian ialah survei deskriptif-observasional dengan desain potong lintang. Pengambilan sampel dilakukan dengan teknik purposive sampling pada seluruh pasien di Klinik Advent Efrata Tikala Manado. Variabel penelitian ialah pasien BPH di Klinik Advent Tikala Manado. Instrumen penelitian menggunakan kuesioner IIEF-5 yang telah dimodifikasi. Hasil penelitian mendapatkan berdasarkan lama menderita BPH, responden yang menderita BPH >3 tahun sebesar 75,0%; 1-2 tahun sebesar 17,9%; dan <1 tahun sebesar 7,1%. Berdasarkan usia responden berusia 61-70 tahun sebesar 46,5% dan 41-50 tahun sebesar 7,1%. DE pada BPH paling banyak termasuk klasifikasi sedang (42,9%), diikuti ringan-sedang (32,1%), berat (17,9%) dan ringan (7,1%). Simpulan: Sebagian besar pasien DE dengan BPH >3 tahun termasuk dalam klasifikasi sedang. Kata kunci: disfungsi ereksi, BPH

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