scholarly journals Rosemary (Rosmarinus officinalis L., syn Salvia rosmarinus Spenn.) and Its Topical Applications: A Review

Plants ◽  
2020 ◽  
Vol 9 (5) ◽  
pp. 651 ◽  
Author(s):  
Lucas Malvezzi de Macedo ◽  
Érica Mendes dos Santos ◽  
Lucas Militão ◽  
Louise Lacalendola Tundisi ◽  
Janaína Artem Ataide ◽  
...  

Topical application is an important administration route for drugs requiring local action on the skin, thereby avoiding their systemic absorption and adverse side effects. Rosmarinus officinalis L. (syn. Salvia rosmarinus Spenn.), popularly known as rosemary, is an aromatic plant with needle-like leaves belonging to the Lamiaceae family. Rosemary has therapeutic properties and has been used in the folk medicine, pharmaceutical, and cosmetics industries, mainly for its antioxidant and anti-inflammatory properties, which are attributed to the presence of carnosol/carnosic and ursolic acids. The therapeutic use of rosemary has been explored for the treatment of inflammatory diseases; however, other uses have been studied, such as wound healing and skin cancer and mycoses treatments, among others. Besides it therapeutic uses, rosemary has potential applications in cosmetic formulations and in the treatment of pathological and non-pathological conditions, such as cellulite, alopecia, ultraviolet damage, and aging. This review aims to critically discuss the topical applications of rosemary found in the literature while also offering relevant information for the development of topical formulations of its bioactive compounds.

Cosmetics ◽  
2020 ◽  
Vol 7 (4) ◽  
pp. 77
Author(s):  
Francisco José González-Minero ◽  
Luis Bravo-Díaz ◽  
Antonio Ayala-Gómez

This work is a bibliographical review of rosemary (Rosmarinus officinalis) that focuses on the application of derivatives of this plant for cosmetic products, an application which has been recognized and valued since Ancient Egyptian times. Rosemary is a plant of Mediterranean origin that has been distributed throughout different areas of the world. It has many medicinal properties, and its extracts have been used (mainly orally) in folk medicine. It belongs to the Labiatae family, which contains several genera—such as Salvia, Lavandula, and Thymus—that are commonly used in cosmetics, due to their high prevalence of antioxidant molecules. Rosemary is a perennial shrub that grows in the wild or is cultivated. It has glandular hairs that emit fragrant volatile essential oils (mainly monoterpenes) in response to drought conditions in the Mediterranean climate. It also contains diterpenes such as carnosic acid and other polyphenolic molecules. Herein, the botanical and ecological characteristics of the plant are discussed, as well as the main bioactive compounds found in its volatile essential oil and in leaf extracts. Afterward, we review the applications of rosemary in cosmetics, considering its preservative power, the kinds of products in which it is used, and its toxicological safety, as well as its current uses or future applications in topical preparations, according to recent and ongoing studies.


2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Myrna Déciga-Campos ◽  
Karla Lizet Beltrán-Villalobos ◽  
Hidemi Aguilar-Mariscal ◽  
María Eva González-Trujano ◽  
Guadalupe Esther Ángeles-López ◽  
...  

The use of alternative medicine to treat pain has been increased, and the combination of several medicinal plants for its relief is a common practice in traditional medicine. The present study is aimed at determining whether a combination of Syzygium aromaticum (S. aromaticum) and Rosmarinus officinalis L. (R. officinalis) potentiates their antinociceptive and anti-inflammatory effects. These effects were explored using the formalin and carrageenan assays in rats, respectively. Animals received local pretreatment with S. aromaticum oil or R. officinalis ethanolic extract (0.1–100 μg/paw) alone or combined in a 1 : 1 rate. Concentration-response curves were built to compare pharmacological responses after an individual administration of S. aromaticum, R. officinalis, or their combination. The pharmacological interaction was investigated by an isobolographic study using the EC50 of each component in a fixed 1 : 1 ratio. S. aromaticum and R. officinalis administered alone showed significant and concentration-dependent antinociceptive and anti-inflammatory effects, but R. officinalis was more potent than S. aromaticum in both the antinociceptive and anti-inflammatory effects (EC50 = 7.96 ± 0.6 μg/paw vs. EC50 = 41.6 ± 1.7 μg/paw; EC50 = 1.97 ± 0.3 μg/paw vs. EC50 = 26.9 ± 2.5 μg/paw, respectively). The isobolographic analysis of the combination of these species in a 1 : 1 ratio showed a synergistic interaction between S. aromaticum and R. officinalis since Zmix (experimental value) was lower than Zadd (theoretical value) for both the antinociceptive effect (Zmix = 0.45 ± 0.1 < Zadd = 24.8 ± 1.3) and the anti-inflammatory effect (Zmix = 5.2 ± 0.6 < Zadd = 14.4 ± 2.2), suggesting a potentiation for both pharmacological effects. These results prove evidence of the efficacy of mixture herb-herb used in folk medicine for pain therapy. It also emphasizes the requirement of pharmacological studies to explore the efficacy and safety of herb interactions.


2019 ◽  
Vol 2 (2) ◽  
pp. 16
Author(s):  
Eloisa Lorenzetti ◽  
Dablieny Hellen Garcia Souza ◽  
Juliano Tartaro ◽  
José Renato Stangarlin ◽  
Gilberto Costa Braga

A banana apresenta elevada suscetibilidade a doenças como as podridões que diminuem o tempo de prateleira do fruto. Uma das formas de controlar as doenças seria a utilização de métodos alternativos como os extratos de plantas medicinais. Assim, o objetivo deste estudo foi verificar a ação de formulados de alecrim (Rosmarinus officinalis L.) pó e líquido no controle de antracnose causada pelo fungo Colletotrichum musae (Berk & Curt.) Von Arx. e na maturação de banana ‘Nanicão’ em pós-colheita. Foram utilizadas as concentrações 0%; 0,25%; 0,5%; 1%; 1,5% e 2% do pó solúvel de extrato de alecrim diluído em água destilada, e as concentrações 0%; 0,5%; 1%; 2%; 4% e 6% do formulado aquoso contendo 21% de resíduo seco de alecrim diluído em água destilada. Foi realizada a mensuração da área de cada fruto e avaliada a severidade e a maturação a partir de porcentagem de área dos frutos, sendo os resultados utilizados para calcular a área abaixo da curva de progresso da doença (AACPD) e a porcentagem de maturação dos frutos. Realizou-se analise de regressão a partir dos dados obtidos e pode-se verificar que para o formulado de alecrim em pó a AACPD reduziu mais de 29% e para a maturação a redução foi de 21,72%. Para o formulado líquido a redução foi de 14,31% para AACPD e cerca de 10% para maturação. Assim, concluiu-se que houve eficiência por parte dos formulados de alecrim no controle da antracnose e no aumento da vida de prateleira da banana ‘Nanicão’.


2016 ◽  
Vol 72 (9) ◽  
Author(s):  
Dr. Ayman Salah El-Seedy ◽  
Hany George Shalaby ◽  
Mohamed Ahmed El-Sehrigy ◽  
Madiha Mohiy El-Dein Ghoneim

2020 ◽  
Vol 06 ◽  
Author(s):  
Saheed Sabiu ◽  
Christiana Eleojo Aruwa ◽  
Viresh Mohanlall ◽  
Himansu Baijnath

Background: Momordica balsamina L. is a monoecious climbing vine and perennial herb native to the tropical regions of Asia, Arabia and the Caribbean, and with prominent presence in Nigeria, Botswana, Namibia, Swaziland and Southern African provinces. While evidence of its anecdotal usage as medicine exist, scientific reports complementing the claims are still emerging or at their infancy. Objective: This review appraised the morphology, therapeutic and biotechnological significance of M. balsamina. Method: Online resources such as Google Scholar, PubMed, ScienceDirect and MeSH were utilized for literature search and included relevant information from inception till May 2020 to streamline sought outcomes for in-depth discussion. Results: The data gathered and considered worthy of inclusion in this study revealed that M. balsamina is rich in phytonutrients of medicinal significance with cucurbitane-type triterpenoids, balsamin and momordins well characterized and fully elucidated. These compounds and other novel bioactive agents in M. balsamina have found remarkable pharmacological relevance and could further be harnessed for use against several debilitating human disorders. Conclusion: The potential applications of M. balsamina as nutraceutical and pharmaceutical agent should not be undermined. Also, with the inadequate toxicological data on this wild species, its consumption should be with caution and translational studies that could advance scientific knowledge and aid better understanding of both its pharmacokinetics and pharmacodynamics without sidelining its potent biotechnological applications are highly encouraged. It is hoped that this paper will provide baseline information that could serve as a guide and inspiration for further studies on the prospects of M. balsamina.


2011 ◽  
Vol 44 (5) ◽  
pp. 1541-1548 ◽  
Author(s):  
Geíza Alves de Azeredo ◽  
Tânia Lúcia Montenegro Stamford ◽  
Pollyana Campos Nunes ◽  
Nelson Justino Gomes Neto ◽  
Maria Elieidy Gomes de Oliveira ◽  
...  

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